Loading...


  • asenapine
  • Based on its extremely high, unequaled (among antipsychotics) affinity for the 5-HT2A, 5-HT2C, 5-HT6, and 5-HT7 receptors, and high affinity for the H1 receptor, asenapine, given normal tolerability, should theoretically demonstrate among the highest improvements in the negative symptomology of schizophrenia among all current antipsychotics (August 2017), such as high cognitive improvements and positive mood maintenance. (wikipedia.org)
  • treatment
  • Since the randomization in the study until the start with subcutaneous trastuzumab , patients will receive a treatment cycle of intravenous trastuzumab as usual. (clinicaltrials.gov)
  • Patients will be randomised by a dynamic randomisation method called minimization which allocates patients to treatment group by checking the allocation of similar patients already randomised, and allocating the next treatment group 'live' to best balance the treatment groups across all stratification variables. (clinicaltrials.gov)
  • Ezetimibe also is an acceptable treatment option for patients with hyperlipidemia who are intolerant of statins, as long as they understand that there is no proven benefit regarding clinical outcomes. (aafp.org)
  • On the fifth day of treatment, patient will be hospitalized in the clinical trial unit in order to obtaine plasma concentrations previous to the administration of the corresponding dose (basal) and at the following times post-administration: 30min, 1h, 1h30min, 2h, 3h, 4h, 6h, 8h, and 12h. (clinicaltrials.gov)
  • I am extremely pleased with and impressed by the culture conversion results that ALIS demonstrated in treatment-refractory patients with NTM lung disease caused by MAC. (pharmiweb.com)
  • The eradication of MAC is the first and most important goal for treatment of patients with MAC lung disease," said David Griffith, M.D., Professor of Medicine, W.A and E.B. Moncrief Distinguished Professor at The University of Texas Health Sciences Center and Principal Investigator in the CONVERT study. (pharmiweb.com)
  • Today marks an important advance in our quest to bring a safe and effective treatment to patients who suffer from NTM lung disease caused by MAC. (pharmiweb.com)
  • In other words, 90% of patients are responding to a treatment. (sciencemag.org)
  • Lesinurad: Positive top-line results from CLEAR1 and CLEAR2, the pivotal Phase III clinical trials investigating the potential of lesinurad, a selective uric acid re-absorption inhibitor (SURI), as a combination therapy with xanthine oxidase (XO) inhibitor, allopurinol for the treatment of patients with symptomatic gout. (astrazeneca.se)
  • Patients whose tumor(s) are not suitable for other local treatment, such as surgery, trans-arterial chemoembolization (TAE), ethanol injection, or radiofrequency ablation. (knowcancer.com)
  • HIV-infected patients taking cenicriviroc had significant reductions in viral load, with the effect persisting up to two weeks after discontinuation of treatment. (wikipedia.org)
  • American Psychiatric Association treatment guidelines recommend that initial treatment should be individually tailored based on factors that include severity of symptoms, co-existing disorders, prior treatment experience, and patient preference. (wikipedia.org)
  • They recommended antidepressant medication as an initial treatment choice in people with mild, moderate, or severe major depression, that should be given to all patients with severe depression unless ECT is planned. (wikipedia.org)
  • Clozapine is an effective treatment for those who respond poorly to other drugs, but it has the potentially serious side effect of agranulocytosis (lowered white blood cell count) in 1-4% of patients. (wikipedia.org)
  • NCI) An AE is any untoward medical occurrence in a patient or clinical investigation subject administered a pharmaceutical product and that does not necessarily have a causal relationship with this treatment. (wikipedia.org)
  • study
  • Patients were recruited into a prospective national multicenter cohort study for an observational period of 2 years. (biomedcentral.com)
  • At the start of the study, patients opted to use a digital (DiD) or paper diary (PD) to document self-administered injections of interferon beta-1b. (biomedcentral.com)
  • GEICAM/2012-07 is a study phase III, prospective, open, randomized, multicenter and national designed to assess patient preference for intravenous (IV) or subcutaneous (SC) of trastuzumab , and within the SC by the administration through the vial or device self-administration in patients with disseminated breast cancer HER2. (clinicaltrials.gov)
  • To the recruiting time alkoholabstinently living, i.e. after successful alcohol decontamination, the patients must have understood the meaning and consequence of the study and have delivered before beginning of study your written agreement to the participation. (clinicaltrials.gov)
  • The number of patients undergoing the randomisation procedure, the number of patients who completed the study and the number of improved patients were extracted. (biopsychiatry.com)
  • In the tolerability analysis, the number of patients failing to complete the study and the number of patients complaining of side-effects was extracted. (biopsychiatry.com)
  • Tolerability of a particular drug can be discussed in a general sense, or it can be a quantifiable measurement as part of a clinical study. (wikipedia.org)
  • For instance, cancer patients will generally tolerate an immense amount of pain or discomfort during a chemotherapeutic study with the hope of prolonging survival or finding a cure, whereas patients experiencing a benign condition, such as a headache, will not. (wikipedia.org)
  • Patients with cancer pain who meet entrance criteria for the study will be identified. (knowcancer.com)
  • A single dose pharmacokinetic study of raltegravir in patients with mild to moderate hepatic insufficiency (Steigbigel et al. (clinicaltrials.gov)
  • Phase I, Open Label, Unicentric Study of Multiple-dose Pharmacokinetics of Raltegravir in Patients Infected With Human Immunodeficiency Virus and Hepatitis C Virus With and Without Advanced (Child-Pugh C) Hepatic Cirrhosis. (clinicaltrials.gov)
  • INSM ), a global biopharmaceutical company focused on the unmet needs of patients with rare diseases, today announced top-line data from its Phase 3 CONVERT study. (pharmiweb.com)
  • The CONVERT study enrolled 336 adult patients with NTM lung disease caused by MAC who were refractory to at least six months of GBT. (pharmiweb.com)
  • Although it is not a parameter routinely used in clinical practice, I also find it encouraging that patients who achieved culture conversion showed improvement in 6-minute walk distance, a quality of life parameter, as was seen in a prior ALIS study. (pharmiweb.com)
  • This is a pilot study of concomitant radiotherapy and thalidomide for patients with locally advanced HCC. (knowcancer.com)
  • burden
  • However, the burden of side-effects in patients receiving it was greater. (biopsychiatry.com)
  • The results confirm the hypothesis that rIFN -2b preferentially targets the malignant clone in PV and raises the possibility that the JAK2V617F allele burden, and a reversion of clonal hematopoiesis monitored in females by expression of X-chromosome polymorphic alleles maybe useful in monitoring minimal residual disease in PV patients. (clinicaltrials.gov)
  • rates
  • Although dropout rates for toxicity were low, that is not to say the therapy was without symptomatic toxicity, and indeed a spectrum of toxicities might be encountered and need to be weighed in the analysis of the net clinical benefit patients experience on a clinical trial with Pegylated Interferon Alfa-2a. (clinicaltrials.gov)
  • Phase IIb data presented at the 20th Conference on Retroviruses and Opportunistic Infections (CROI) in March 2013 showed similar viral suppression rates of 76% for patients taking 100 mg cenicriviroc, 73% with 200 mg cenicriviroc, and 71% with efavirenz. (wikipedia.org)
  • Non-response rates were higher with cenicriviroc, however, largely due to greater drop-out of patients. (wikipedia.org)
  • therapy
  • Non-adherence of MS patients to their DMD may be defined as either termination of therapy or interruption of regular administration. (biomedcentral.com)
  • Ezetimibe is reasonable adjunct therapy for patients who have not reached LDL goals on maximum statin dosage or who cannot tolerate maximum doses of statins. (aafp.org)
  • This controlled-release patch formulation offers the advantage of achieving more consistent drug delivery in a convenient, noninvasive way and could contribute to improved patient adherence to therapy. (knowcancer.com)
  • 1.3 Patients without any local or systemic therapy for HCC within 4 weeks. (knowcancer.com)
  • 1.6.6 Serum creatinine tumors less than one half of the whole liver and the tumors can be encompassed within RT fields 1.8 Signed informed consent 1.9 Sexually active patients, in conjunction with their partner, must practice birth control during, and for 2 months after, thalidomide therapy. (knowcancer.com)
  • Patients who have major systemic diseases that the attending physicians consider inappropriate for radiotherapy or thalidomide therapy. (knowcancer.com)
  • psychosis
  • Behavioural and psychological symptoms in dementia (BPSD), such as agitation, aggression and psychosis, occur at some point in over 80% of patients with dementia ( Ballard et al , 1995 ). (rcpsych.org)
  • proportion of patients
  • however, the estimate of the proportion of patients who experienced side-effects significantly favoured control agents in comparison with amitriptyline (odds ratio 0.63, 95% confidence interval 0.56, 0.71). (biopsychiatry.com)
  • interferon
  • Interferon (rIFN -2b), is a drug that appears to be non-leukemogenic, and may have a preferential activity on the malignant clone in PV, as suggested by cytogenetic remissions obtained in patients treated with rIFN -2b. (clinicaltrials.gov)
  • Primary
  • Out-patients with alcohol dependence recently detoxified Primary goal size is the duration of the Abstinenz up to the heavy relapse. (clinicaltrials.gov)
  • These disorders include Polycythemia Vera (PV), Essential Thrombocythemia (ET) and Primary Myelofibrosis (PM). Recently an acquired somatic mutation in the intracellular kinase, JAK2 (JAK2V617F) has been observed in 95% of patients with PV, 50% of patients with ET and 50% of patients with primary myelofibrosis. (clinicaltrials.gov)
  • outcomes
  • Patient-related health outcomes will also be evaluated. (biomedcentral.com)
  • Ezetimibe is safe and effective for lowering LDL cholesterol and triglyceride levels but has not been shown to affect patient-oriented outcomes. (aafp.org)
  • The discussion on effectiveness will include a comparison of the new drug against the drugs in current use, with an emphasis on patient-oriented outcomes rather than physiologic or disease-oriented end points. (aafp.org)
  • symptoms
  • These symptoms are distressing to patients and troublesome to carers, and often precipitate admission to residential facilities. (rcpsych.org)
  • The elderly are particularly vulnerable to these side-effects, and Parkinsonian symptoms reportedly occur in over 50% of all elderly patients receiving these drugs ( Avorn et al , 1994 ). (rcpsych.org)
  • Drug
  • Drug tolerability should not be confused with drug tolerance, which refers to subjects' reduced reaction to a drug following its repeated use. (wikipedia.org)
  • We then address special considerations in the use of antipsychotics in the elderly, including pharmacokinetic and pharmacodynamic changes in ageing, medical comorbidity, drug-drug interactions and tolerability. (rcpsych.org)
  • alcohol
  • 1.1 Patients with measurable, locally advanced HCC that are not suitable for other local therapies, including surgery, TAE, alcohol injection, or radiofrequency ablation. (knowcancer.com)
  • injection
  • 383 patients opted for the digital diary, 192 of which included an injection reminder. (biomedcentral.com)
  • Approximately 195 patients will be included to receive subcutaneous trastuzumab a fixed dose of 600 mg every 3 weeks for 4 cycles (2 administered from the injection of a vial with a syringe and 2 with the injection device). (clinicaltrials.gov)
  • investigators
  • The investigators hypothesized that pharmacokinetics will not be altered in HIV/HCV patients with advanced (Child-Pugh grade C) cirrhosis or in those with no histologic liver damage. (clinicaltrials.gov)
  • Several investigators recently reported that patients with PV treated with rIFN -2b had lower JAK2V617F allele burdens as compared to a control group that included patients treated with phlebotomy, hydroxyurea, or anagrelide, or who remained untreated. (clinicaltrials.gov)
  • less
  • Atypicals are less likely than haloperidol - the most widely used typical antipsychotic - to cause extrapyramidal motor control disabilities in patients such as unsteady Parkinson's disease-type movements, body rigidity, and involuntary tremors. (wikipedia.org)
  • quality
  • Up to one in four patients with diabetes may be affected by chronic diabetic painful neuropathy (DPN) ( 1 , 2 ) and suffer substantial morbidity and impaired quality of life ( 3 ). (diabetesjournals.org)
  • chronic
  • 1.2 Patients with histological confirmed HCC or patients who do not have histological diagnosis but have met all of the following criteria: 1.2.1 Presence of chronic viral hepatitis and/or cirrhosis 1.2.2 Presence of hepatic tumor(s) with image findings (sonography, CT scan) compatible with HCC. (knowcancer.com)
  • diseases
  • Briggs Morrison, Executive Vice President, Global Medicines Development and Chief Medical Officer, AstraZeneca, said: "The breadth of research we will present at ACR reinforces our commitment to delivering medicines that could help to improve the lives of millions of patients suffering from inflammation and autoimmune diseases. (astrazeneca.se)
  • We continue to push scientific boundaries, advancing our understanding of the drivers and mechanisms of these diseases for the benefit of patients. (astrazeneca.se)
  • Patients with other systemic diseases that required concurrent usage of glucocorticosteroid or immunosuppressant agent(s). (knowcancer.com)
  • phase
  • Its Phase IIb of 147 patients underwent different dosages of Bryostatin along different timelines to see which worked best. (sciencemag.org)
  • asenapine
  • Based on its extremely high, unequaled (among antipsychotics) affinity for the 5-HT2A, 5-HT2C, 5-HT6, and 5-HT7 receptors, and high affinity for the H1 receptor, asenapine, given normal tolerability, should theoretically demonstrate among the highest improvements in the negative symptomology of schizophrenia among all current antipsychotics (August 2017), such as high cognitive improvements and positive mood maintenance. (wikipedia.org)
  • treatment
  • Since the randomization in the study until the start with subcutaneous trastuzumab , patients will receive a treatment cycle of intravenous trastuzumab as usual. (clinicaltrials.gov)
  • Patients will be randomised by a dynamic randomisation method called minimization which allocates patients to treatment group by checking the allocation of similar patients already randomised, and allocating the next treatment group 'live' to best balance the treatment groups across all stratification variables. (clinicaltrials.gov)
  • Ezetimibe also is an acceptable treatment option for patients with hyperlipidemia who are intolerant of statins, as long as they understand that there is no proven benefit regarding clinical outcomes. (aafp.org)
  • On the fifth day of treatment, patient will be hospitalized in the clinical trial unit in order to obtaine plasma concentrations previous to the administration of the corresponding dose (basal) and at the following times post-administration: 30min, 1h, 1h30min, 2h, 3h, 4h, 6h, 8h, and 12h. (clinicaltrials.gov)
  • I am extremely pleased with and impressed by the culture conversion results that ALIS demonstrated in treatment-refractory patients with NTM lung disease caused by MAC. (pharmiweb.com)
  • The eradication of MAC is the first and most important goal for treatment of patients with MAC lung disease," said David Griffith, M.D., Professor of Medicine, W.A and E.B. Moncrief Distinguished Professor at The University of Texas Health Sciences Center and Principal Investigator in the CONVERT study. (pharmiweb.com)
  • Today marks an important advance in our quest to bring a safe and effective treatment to patients who suffer from NTM lung disease caused by MAC. (pharmiweb.com)
  • In other words, 90% of patients are responding to a treatment. (sciencemag.org)
  • Lesinurad: Positive top-line results from CLEAR1 and CLEAR2, the pivotal Phase III clinical trials investigating the potential of lesinurad, a selective uric acid re-absorption inhibitor (SURI), as a combination therapy with xanthine oxidase (XO) inhibitor, allopurinol for the treatment of patients with symptomatic gout. (astrazeneca.se)
  • Patients whose tumor(s) are not suitable for other local treatment, such as surgery, trans-arterial chemoembolization (TAE), ethanol injection, or radiofrequency ablation. (knowcancer.com)
  • HIV-infected patients taking cenicriviroc had significant reductions in viral load, with the effect persisting up to two weeks after discontinuation of treatment. (wikipedia.org)
  • American Psychiatric Association treatment guidelines recommend that initial treatment should be individually tailored based on factors that include severity of symptoms, co-existing disorders, prior treatment experience, and patient preference. (wikipedia.org)
  • They recommended antidepressant medication as an initial treatment choice in people with mild, moderate, or severe major depression, that should be given to all patients with severe depression unless ECT is planned. (wikipedia.org)
  • Clozapine is an effective treatment for those who respond poorly to other drugs, but it has the potentially serious side effect of agranulocytosis (lowered white blood cell count) in 1-4% of patients. (wikipedia.org)
  • NCI) An AE is any untoward medical occurrence in a patient or clinical investigation subject administered a pharmaceutical product and that does not necessarily have a causal relationship with this treatment. (wikipedia.org)
  • study
  • Patients were recruited into a prospective national multicenter cohort study for an observational period of 2 years. (biomedcentral.com)
  • At the start of the study, patients opted to use a digital (DiD) or paper diary (PD) to document self-administered injections of interferon beta-1b. (biomedcentral.com)
  • GEICAM/2012-07 is a study phase III, prospective, open, randomized, multicenter and national designed to assess patient preference for intravenous (IV) or subcutaneous (SC) of trastuzumab , and within the SC by the administration through the vial or device self-administration in patients with disseminated breast cancer HER2. (clinicaltrials.gov)
  • To the recruiting time alkoholabstinently living, i.e. after successful alcohol decontamination, the patients must have understood the meaning and consequence of the study and have delivered before beginning of study your written agreement to the participation. (clinicaltrials.gov)
  • The number of patients undergoing the randomisation procedure, the number of patients who completed the study and the number of improved patients were extracted. (biopsychiatry.com)
  • In the tolerability analysis, the number of patients failing to complete the study and the number of patients complaining of side-effects was extracted. (biopsychiatry.com)
  • Tolerability of a particular drug can be discussed in a general sense, or it can be a quantifiable measurement as part of a clinical study. (wikipedia.org)
  • For instance, cancer patients will generally tolerate an immense amount of pain or discomfort during a chemotherapeutic study with the hope of prolonging survival or finding a cure, whereas patients experiencing a benign condition, such as a headache, will not. (wikipedia.org)
  • Patients with cancer pain who meet entrance criteria for the study will be identified. (knowcancer.com)
  • A single dose pharmacokinetic study of raltegravir in patients with mild to moderate hepatic insufficiency (Steigbigel et al. (clinicaltrials.gov)
  • Phase I, Open Label, Unicentric Study of Multiple-dose Pharmacokinetics of Raltegravir in Patients Infected With Human Immunodeficiency Virus and Hepatitis C Virus With and Without Advanced (Child-Pugh C) Hepatic Cirrhosis. (clinicaltrials.gov)
  • INSM ), a global biopharmaceutical company focused on the unmet needs of patients with rare diseases, today announced top-line data from its Phase 3 CONVERT study. (pharmiweb.com)
  • The CONVERT study enrolled 336 adult patients with NTM lung disease caused by MAC who were refractory to at least six months of GBT. (pharmiweb.com)
  • Although it is not a parameter routinely used in clinical practice, I also find it encouraging that patients who achieved culture conversion showed improvement in 6-minute walk distance, a quality of life parameter, as was seen in a prior ALIS study. (pharmiweb.com)
  • This is a pilot study of concomitant radiotherapy and thalidomide for patients with locally advanced HCC. (knowcancer.com)
  • burden
  • However, the burden of side-effects in patients receiving it was greater. (biopsychiatry.com)
  • The results confirm the hypothesis that rIFN -2b preferentially targets the malignant clone in PV and raises the possibility that the JAK2V617F allele burden, and a reversion of clonal hematopoiesis monitored in females by expression of X-chromosome polymorphic alleles maybe useful in monitoring minimal residual disease in PV patients. (clinicaltrials.gov)
  • rates
  • Although dropout rates for toxicity were low, that is not to say the therapy was without symptomatic toxicity, and indeed a spectrum of toxicities might be encountered and need to be weighed in the analysis of the net clinical benefit patients experience on a clinical trial with Pegylated Interferon Alfa-2a. (clinicaltrials.gov)
  • Phase IIb data presented at the 20th Conference on Retroviruses and Opportunistic Infections (CROI) in March 2013 showed similar viral suppression rates of 76% for patients taking 100 mg cenicriviroc, 73% with 200 mg cenicriviroc, and 71% with efavirenz. (wikipedia.org)
  • Non-response rates were higher with cenicriviroc, however, largely due to greater drop-out of patients. (wikipedia.org)
  • therapy
  • Non-adherence of MS patients to their DMD may be defined as either termination of therapy or interruption of regular administration. (biomedcentral.com)
  • Ezetimibe is reasonable adjunct therapy for patients who have not reached LDL goals on maximum statin dosage or who cannot tolerate maximum doses of statins. (aafp.org)
  • This controlled-release patch formulation offers the advantage of achieving more consistent drug delivery in a convenient, noninvasive way and could contribute to improved patient adherence to therapy. (knowcancer.com)
  • 1.3 Patients without any local or systemic therapy for HCC within 4 weeks. (knowcancer.com)
  • 1.6.6 Serum creatinine tumors less than one half of the whole liver and the tumors can be encompassed within RT fields 1.8 Signed informed consent 1.9 Sexually active patients, in conjunction with their partner, must practice birth control during, and for 2 months after, thalidomide therapy. (knowcancer.com)
  • Patients who have major systemic diseases that the attending physicians consider inappropriate for radiotherapy or thalidomide therapy. (knowcancer.com)
  • psychosis
  • Behavioural and psychological symptoms in dementia (BPSD), such as agitation, aggression and psychosis, occur at some point in over 80% of patients with dementia ( Ballard et al , 1995 ). (rcpsych.org)
  • proportion of patients
  • however, the estimate of the proportion of patients who experienced side-effects significantly favoured control agents in comparison with amitriptyline (odds ratio 0.63, 95% confidence interval 0.56, 0.71). (biopsychiatry.com)
  • interferon
  • Interferon (rIFN -2b), is a drug that appears to be non-leukemogenic, and may have a preferential activity on the malignant clone in PV, as suggested by cytogenetic remissions obtained in patients treated with rIFN -2b. (clinicaltrials.gov)
  • Primary
  • Out-patients with alcohol dependence recently detoxified Primary goal size is the duration of the Abstinenz up to the heavy relapse. (clinicaltrials.gov)
  • These disorders include Polycythemia Vera (PV), Essential Thrombocythemia (ET) and Primary Myelofibrosis (PM). Recently an acquired somatic mutation in the intracellular kinase, JAK2 (JAK2V617F) has been observed in 95% of patients with PV, 50% of patients with ET and 50% of patients with primary myelofibrosis. (clinicaltrials.gov)
  • outcomes
  • Patient-related health outcomes will also be evaluated. (biomedcentral.com)
  • Ezetimibe is safe and effective for lowering LDL cholesterol and triglyceride levels but has not been shown to affect patient-oriented outcomes. (aafp.org)
  • The discussion on effectiveness will include a comparison of the new drug against the drugs in current use, with an emphasis on patient-oriented outcomes rather than physiologic or disease-oriented end points. (aafp.org)
  • symptoms
  • These symptoms are distressing to patients and troublesome to carers, and often precipitate admission to residential facilities. (rcpsych.org)
  • The elderly are particularly vulnerable to these side-effects, and Parkinsonian symptoms reportedly occur in over 50% of all elderly patients receiving these drugs ( Avorn et al , 1994 ). (rcpsych.org)
  • Drug
  • Drug tolerability should not be confused with drug tolerance, which refers to subjects' reduced reaction to a drug following its repeated use. (wikipedia.org)
  • We then address special considerations in the use of antipsychotics in the elderly, including pharmacokinetic and pharmacodynamic changes in ageing, medical comorbidity, drug-drug interactions and tolerability. (rcpsych.org)
  • alcohol
  • 1.1 Patients with measurable, locally advanced HCC that are not suitable for other local therapies, including surgery, TAE, alcohol injection, or radiofrequency ablation. (knowcancer.com)
  • injection
  • 383 patients opted for the digital diary, 192 of which included an injection reminder. (biomedcentral.com)
  • Approximately 195 patients will be included to receive subcutaneous trastuzumab a fixed dose of 600 mg every 3 weeks for 4 cycles (2 administered from the injection of a vial with a syringe and 2 with the injection device). (clinicaltrials.gov)
  • investigators
  • The investigators hypothesized that pharmacokinetics will not be altered in HIV/HCV patients with advanced (Child-Pugh grade C) cirrhosis or in those with no histologic liver damage. (clinicaltrials.gov)
  • Several investigators recently reported that patients with PV treated with rIFN -2b had lower JAK2V617F allele burdens as compared to a control group that included patients treated with phlebotomy, hydroxyurea, or anagrelide, or who remained untreated. (clinicaltrials.gov)
  • less
  • Atypicals are less likely than haloperidol - the most widely used typical antipsychotic - to cause extrapyramidal motor control disabilities in patients such as unsteady Parkinson's disease-type movements, body rigidity, and involuntary tremors. (wikipedia.org)
  • quality
  • Up to one in four patients with diabetes may be affected by chronic diabetic painful neuropathy (DPN) ( 1 , 2 ) and suffer substantial morbidity and impaired quality of life ( 3 ). (diabetesjournals.org)
  • chronic
  • 1.2 Patients with histological confirmed HCC or patients who do not have histological diagnosis but have met all of the following criteria: 1.2.1 Presence of chronic viral hepatitis and/or cirrhosis 1.2.2 Presence of hepatic tumor(s) with image findings (sonography, CT scan) compatible with HCC. (knowcancer.com)
  • diseases
  • Briggs Morrison, Executive Vice President, Global Medicines Development and Chief Medical Officer, AstraZeneca, said: "The breadth of research we will present at ACR reinforces our commitment to delivering medicines that could help to improve the lives of millions of patients suffering from inflammation and autoimmune diseases. (astrazeneca.se)
  • We continue to push scientific boundaries, advancing our understanding of the drivers and mechanisms of these diseases for the benefit of patients. (astrazeneca.se)
  • Patients with other systemic diseases that required concurrent usage of glucocorticosteroid or immunosuppressant agent(s). (knowcancer.com)
  • phase
  • Its Phase IIb of 147 patients underwent different dosages of Bryostatin along different timelines to see which worked best. (sciencemag.org)