• dentistry
  • The theory of Guided tissue regeneration has been challenged in dentistry. (wikipedia.org)
  • Additionally, due to the inordinate amount of control and broad range of possible porous microstructures that freeze-casting can produce, the technique has found its niche in a number of disparate fields such as tissue scaffolds, photonics, metal-matrix composites, dentistry, materials science, and even food science There are three possible end results to uni-directionally freezing a suspension of particles. (wikipedia.org)
  • Headquartered in Basel, Switzerland, the Straumann Group (SIX: STMN) acts in implant and restorative dentistry and oral tissue regeneration. (wikipedia.org)
  • scaffold materials
  • For many years research has been dedicated to understanding the biochemical environment that is required to encourage bone regeneration and the desired properties of biocompatible scaffold materials. (nuigalway.ie)
  • Researchers at Rice University, Stony Brook University, Radboud University Nijmegen Medical Centre and University of California, Riverside have shown that carbon nanotubes and their polymer nanocomposites are suitable scaffold materials for bone tissue engineering and bone formation. (wikipedia.org)
  • cortical bone
  • We hypothesize the joining of a porous trabecular scaffold with the addition of hydroxyapatite (HAp), pre-vascularized cortical bone scaffold and HAp columns will promote the differentiation of human mesenchymal stem cells (hMSCs) along the osteoblastic and angiogenic lineage for improved mechanics and graft viability in vivo. (rutgers.edu)
  • amount of bone
  • A diagnosis of periodontitis is established by inspecting the soft gum tissues around the teeth with a probe (i.e., a clinical examination) and by evaluating the patient's X-ray films (i.e., a radiographic examination), to determine the amount of bone loss around the teeth. (wikipedia.org)
  • osteogenic
  • Together with Nuno Pires he won the prize for the Altis Osteogenic Bone Matrix. (wikipedia.org)
  • July 1996) Recombinant transforming growth factor-beta1 induces endochondral bone in the baboon and synergizes with recombinant osteogenic protein-1 (bone morphogenetic protein-7) to initiate rapid bone formation. (wikipedia.org)
  • October 1997) Transforming growth factor-beta 1: induction of bone morphogenetic protein genes expression during endochondral bone formation in the baboon, and synergistic interaction with osteogenic protein-1 (BMP-7). (wikipedia.org)
  • teeth
  • Periodontal or gum disease causes bone loss around teeth, which can increase the chances for tooth loss. (sacperio.com)
  • When gum disease is present, this supporting tissue and bone are destroyed and pockets in between the teeth and gums develop. (sacperio.com)
  • By repairing the damage caused by gum disease, this procedure will increase the chances of keeping your natural teeth by preventing further bone loss and will decrease the odds of serious health problems associated with gum disease. (sacperio.com)
  • For those patients that would benefit from replacing missing teeth with dental implants, guided tissue regeneration may first be recommended by your doctor. (sacperio.com)
  • If you have lost bone due to missing teeth or gum disease, your doctor can help. (sacperio.com)
  • Transverse expansion or proclination of the teeth are valid alternatives to extraction in cases of crowding, but lack of stability and development of bone dehiscences have been demonstrated as side effects subsequent to anterior displacement of the incisors. (quintpub.com)
  • Eventually, if too much bone is lost, the teeth will need to be extracted. (drgums.com)
  • There are many options to enhance support for your teeth and to restore your bone to a healthy level. (drgums.com)
  • Periodontitis, also known as gum disease and pyorrhea, is a set of inflammatory diseases affecting the tissues surrounding the teeth. (wikipedia.org)
  • Periodontitis involves progressive loss of the alveolar bone around the teeth, and if left untreated, can lead to the loosening and subsequent loss of teeth. (wikipedia.org)
  • Deep pockets between the teeth and the gums (pockets are sites where the attachment has been gradually destroyed by collagen-destroying enzymes, known as collagenases) Loose teeth, in the later stages (though this may occur for other reasons, as well) Patients should realize gingival inflammation and bone destruction are largely painless. (wikipedia.org)
  • Periodontitis is an inflammation of the periodontium, i.e., the tissues that support the teeth. (wikipedia.org)
  • severely resorbed
  • Eight patients with tumor resection for oral cancer and severely resorbed maxillary bone received materials according to a split mouth design for 6 months. (uzh.ch)
  • Restorative
  • Socket preservation procedure prevents immediate bone resorption after extraction thus keeping the contour and integrity of the socket with successful and natural looking appearance for tooth restorative procedures. (wikipedia.org)
  • vitro
  • Materials and Methods: In vitro and in vivo analyses of the tissue-engineered constructs were conducted using imaging techniques, immunohistochemistry, and histology. (quintpub.com)
  • mechanical
  • 4 . A process according to claim 1 , characterized in that the tissue is one of a type wherein cell proliferation and differentiation is initiated through bio-mechanical transmission of stimuli onto the cytoscleleton and growth or regeneration of tissue can be attained. (google.es)
  • Most TE options for bone replacement seek to replace only the trabecular bone leading to low mechanical properties or lack the ability to promote early vascularization in vivo. (rutgers.edu)
  • Material characterization of the scaffold confirmed pore ranges necessary for neovascularization and osteoblast infiltration and mechanical properties comparable to native bone. (rutgers.edu)
  • Poor mechanical properties, short degradation time, and the lack of integrated biologic components result in the inability to create and maintain an appropriate environment and to actively support tissue remodeling. (quintpub.com)
  • Researchers from Rice University and State University of New York - Stony Brook have shown that the addition of low weight % of carbon nanotubes can lead to significant improvements in the mechanical properties of biodegradable polymeric nanocomposites for applications in tissue engineering including bone, cartilage, muscle and nerve tissue. (wikipedia.org)
  • tooth
  • Once a tooth has been lost, the supporting jaw bone has a tendency to disappear over time. (sacperio.com)
  • Eventually, if too much bone is lost as a result of gum disease, the tooth will likely need to be extracted. (sacperio.com)
  • When a fixed bridge is placed, the bone under the pontic, or middle, portion of the bridge where the tooth has been lost has a tendency to sink and can affect the overall facial structure. (sacperio.com)
  • without the strain stimulus, the jaw bone behaves (with or without socket preservation) as if the space occupied by the tooth and periodontal ligament was empty. (wikipedia.org)
  • In collaboration with leading clinics, research institutes, and universities, Straumann researches and develops implants, instruments, and tissue regeneration products for use in tooth replacement solutions or to prevent tooth loss. (wikipedia.org)
  • Preservation
  • Without socket preservation, the bone quickly resorbs resulting in 30-60% loss in bone volume in the six months after dental extraction. (wikipedia.org)
  • Without socket preservation, residual bones could lose volume resulting in loss of facial vertical and horizontal dimension and changes in facial soft tissues aesthetics. (wikipedia.org)
  • hydroxyapatite
  • The present study was first to evaluate the material-specific cellular tissue response of patients with head and neck cancer to a nanocrystalline hydroxyapatite bone substitute NanoBone (NB) in comparison with a deproteinized bovine bone matrix Bio-Oss (BO) after implantation into the sinus cavity. (uzh.ch)
  • porous
  • However the field of tissue regeneration is faced with the specific challenge to develop novel tissue regeneration approaches to produce tissue that can simultaneously support loading, but is also porous to allow for cell migration and diffusion of nutrients into the regenerated tissue to maintain viability. (nuigalway.ie)
  • Porous implantable materials are designed for bone to grow not only onto the material but also into its pores, and in some cases interconnecting within the material's structure, in a process called osseoincorporation. (wikipedia.org)
  • dental
  • The placement of dental implants may also generate the need for guided tissue regeneration. (sacperio.com)
  • All dental prosthesis requires good jaw bone support for it to be successful in the long run. (wikipedia.org)
  • A breakthrough in the use of non-corroding alloys for treating bone fractures prompted Dr Fritz Straumann to enter the fields of orthopedics and dental implantology, which began the second phase of the company's history. (wikipedia.org)
  • 2003 Straumann acquires the Swedish company Biora, a pioneer in the area of biologically based regeneration of dental tissue. (wikipedia.org)
  • Extent
  • No significant difference was observed in the extent of new bone formation between both groups. (uzh.ch)
  • growth
  • 6 . The process according to claim 5 , further comprising the step of initiating and attaining cell proliferation and differentiation through biomechanical transmission of stimuli onto the cytoskeleton and growth or regeneration of tissue. (google.es)
  • The theoretical principles basic to guided tissue regeneration were developed by Melcher in 1976, who outlined the necessity of excluding unwanted cell lines from healing sites to allow growth of desired tissues. (wikipedia.org)