• augmentation
  • Within its limits, the present study showed for the first time that both material classes evaluated, despite their induction of different cellular tissue reactions, may be useful as augmentation materials for dental and maxillofacial surgical applications, particularly in patients who previously had oral cancer. (uzh.ch)
  • In cases where augmentation materials used are autografts or allografts the bone density is quite low and resorption of the grafted site in these cases can reach up to 30% of original volume. (wikipedia.org)
  • in socket preservation, the graft or scaffold is placed inside the tooth socket immediately after extraction, whereas the ridge augmentation grafting procedure is done to bring back the lost bone after the bone has resorbed and there is insufficient ridge height or width for further treatment procedure. (wikipedia.org)
  • Surgically, it is known for its position against using animal or human cadaver products in bone or soft tissue augmentation due to their potential for contamination of the surgical site. (wikipedia.org)
  • Straumann offers surgical, restorative, and regenerative solutions - from bone augmentation and tissue regeneration, through implants and prosthetics, to individualized crowns and bridges. (wikipedia.org)
  • PRF is used in guided bone and tissue regeneration PRF enhances alveolar bone augmentation and necrotic dental pulp and open tooth apex can be revitalized in regenerative endodontics with platelet-rich fibrin. (wikipedia.org)
  • Biomaterials
  • Scientific advances in biomaterials, stem cells, growth and differentiation factors, and biomimetic environments have created unique opportunities to fabricate tissues in the laboratory from combinations of engineered extracellular matrices ("scaffolds"), cells, and biologically active molecules. (wikipedia.org)
  • dentistry
  • The theory of Guided tissue regeneration has been challenged in dentistry. (wikipedia.org)
  • Additionally, due to the inordinate amount of control and broad range of possible porous microstructures that freeze-casting can produce, the technique has found its niche in a number of disparate fields such as tissue scaffolds, photonics, metal-matrix composites, dentistry, materials science, and even food science There are three possible end results to uni-directionally freezing a suspension of particles. (wikipedia.org)
  • Headquartered in Basel, Switzerland, the Straumann Group (SIX: STMN) acts in implant and restorative dentistry and oral tissue regeneration. (wikipedia.org)
  • scaffold materials
  • For many years research has been dedicated to understanding the biochemical environment that is required to encourage bone regeneration and the desired properties of biocompatible scaffold materials. (nuigalway.ie)
  • Researchers at Rice University, Stony Brook University, Radboud University Nijmegen Medical Centre and University of California, Riverside have shown that carbon nanotubes and their polymer nanocomposites are suitable scaffold materials for bone tissue engineering and bone formation. (wikipedia.org)
  • cortical bone
  • We hypothesize the joining of a porous trabecular scaffold with the addition of hydroxyapatite (HAp), pre-vascularized cortical bone scaffold and HAp columns will promote the differentiation of human mesenchymal stem cells (hMSCs) along the osteoblastic and angiogenic lineage for improved mechanics and graft viability in vivo. (rutgers.edu)
  • amount of bone
  • A diagnosis of periodontitis is established by inspecting the soft gum tissues around the teeth with a probe (i.e., a clinical examination) and by evaluating the patient's X-ray films (i.e., a radiographic examination), to determine the amount of bone loss around the teeth. (wikipedia.org)
  • osteogenic
  • Together with Nuno Pires he won the prize for the Altis Osteogenic Bone Matrix. (wikipedia.org)
  • July 1996) Recombinant transforming growth factor-beta1 induces endochondral bone in the baboon and synergizes with recombinant osteogenic protein-1 (bone morphogenetic protein-7) to initiate rapid bone formation. (wikipedia.org)
  • October 1997) Transforming growth factor-beta 1: induction of bone morphogenetic protein genes expression during endochondral bone formation in the baboon, and synergistic interaction with osteogenic protein-1 (BMP-7). (wikipedia.org)
  • field of tissue
  • However the field of tissue regeneration is faced with the specific challenge to develop novel tissue regeneration approaches to produce tissue that can simultaneously support loading, but is also porous to allow for cell migration and diffusion of nutrients into the regenerated tissue to maintain viability. (nuigalway.ie)
  • Powerful developments in the multidisciplinary field of tissue engineering have yielded a novel set of tissue replacement parts and implementation strategies. (wikipedia.org)
  • mechanical properties
  • Most TE options for bone replacement seek to replace only the trabecular bone leading to low mechanical properties or lack the ability to promote early vascularization in vivo. (rutgers.edu)
  • Material characterization of the scaffold confirmed pore ranges necessary for neovascularization and osteoblast infiltration and mechanical properties comparable to native bone. (rutgers.edu)
  • Poor mechanical properties, short degradation time, and the lack of integrated biologic components result in the inability to create and maintain an appropriate environment and to actively support tissue remodeling. (quintpub.com)
  • Researchers from Rice University and State University of New York - Stony Brook have shown that the addition of low weight % of carbon nanotubes can lead to significant improvements in the mechanical properties of biodegradable polymeric nanocomposites for applications in tissue engineering including bone, cartilage, muscle and nerve tissue. (wikipedia.org)
  • surgical
  • There are limitations in treating patients with advanced disease but GTR may be able to achieve regeneration and therefore improve upon conventional surgical results. (wikipedia.org)
  • teeth
  • Periodontal or gum disease causes bone loss around teeth, which can increase the chances for tooth loss. (sacperio.com)
  • When gum disease is present, this supporting tissue and bone are destroyed and pockets in between the teeth and gums develop. (sacperio.com)
  • By repairing the damage caused by gum disease, this procedure will increase the chances of keeping your natural teeth by preventing further bone loss and will decrease the odds of serious health problems associated with gum disease. (sacperio.com)
  • For those patients that would benefit from replacing missing teeth with dental implants, guided tissue regeneration may first be recommended by your doctor. (sacperio.com)
  • If you have lost bone due to missing teeth or gum disease, your doctor can help. (sacperio.com)
  • Transverse expansion or proclination of the teeth are valid alternatives to extraction in cases of crowding, but lack of stability and development of bone dehiscences have been demonstrated as side effects subsequent to anterior displacement of the incisors. (quintpub.com)
  • Eventually, if too much bone is lost, the teeth will need to be extracted. (drgums.com)
  • Dr. Linden may recommend a regenerative procedure if the bone supporting your teeth has been destroyed. (drgums.com)
  • There are many options to enhance support for your teeth and to restore your bone to a healthy level. (drgums.com)
  • Periodontitis, also known as gum disease and pyorrhea, is a set of inflammatory diseases affecting the tissues surrounding the teeth. (wikipedia.org)
  • Periodontitis involves progressive loss of the alveolar bone around the teeth, and if left untreated, can lead to the loosening and subsequent loss of teeth. (wikipedia.org)
  • Deep pockets between the teeth and the gums (pockets are sites where the attachment has been gradually destroyed by collagen-destroying enzymes, known as collagenases) Loose teeth, in the later stages (though this may occur for other reasons, as well) Patients should realize gingival inflammation and bone destruction are largely painless. (wikipedia.org)
  • Periodontitis is an inflammation of the periodontium, i.e., the tissues that support the teeth. (wikipedia.org)
  • severely resorbed
  • Eight patients with tumor resection for oral cancer and severely resorbed maxillary bone received materials according to a split mouth design for 6 months. (uzh.ch)
  • Restorative
  • Socket preservation procedure prevents immediate bone resorption after extraction thus keeping the contour and integrity of the socket with successful and natural looking appearance for tooth restorative procedures. (wikipedia.org)
  • cartilage
  • Play media While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, skin, muscle etc. (wikipedia.org)
  • Cartilage: lab-grown tissue was successfully used to repair knee cartilage. (wikipedia.org)
  • tooth
  • Once a tooth has been lost, the supporting jaw bone has a tendency to disappear over time. (sacperio.com)
  • Eventually, if too much bone is lost as a result of gum disease, the tooth will likely need to be extracted. (sacperio.com)
  • When a fixed bridge is placed, the bone under the pontic, or middle, portion of the bridge where the tooth has been lost has a tendency to sink and can affect the overall facial structure. (sacperio.com)
  • without the strain stimulus, the jaw bone behaves (with or without socket preservation) as if the space occupied by the tooth and periodontal ligament was empty. (wikipedia.org)
  • In collaboration with leading clinics, research institutes, and universities, Straumann researches and develops implants, instruments, and tissue regeneration products for use in tooth replacement solutions or to prevent tooth loss. (wikipedia.org)
  • vascularization
  • In vivo mineralized tissue formation in association with vascularization was observed. (quintpub.com)
  • Among the major challenges now facing tissue engineering is the need for more complex functionality, as well as both functional and biomechanical stability and vascularization in laboratory-grown tissues destined for transplantation. (wikipedia.org)
  • Preservation
  • Without socket preservation, the bone quickly resorbs resulting in 30-60% loss in bone volume in the six months after dental extraction. (wikipedia.org)
  • Without socket preservation, residual bones could lose volume resulting in loss of facial vertical and horizontal dimension and changes in facial soft tissues aesthetics. (wikipedia.org)
  • hydroxyapatite
  • The present study was first to evaluate the material-specific cellular tissue response of patients with head and neck cancer to a nanocrystalline hydroxyapatite bone substitute NanoBone (NB) in comparison with a deproteinized bovine bone matrix Bio-Oss (BO) after implantation into the sinus cavity. (uzh.ch)
  • porous
  • Porous implantable materials are designed for bone to grow not only onto the material but also into its pores, and in some cases interconnecting within the material's structure, in a process called osseoincorporation. (wikipedia.org)
  • materials
  • Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological tissues. (wikipedia.org)
  • The continued success of tissue engineering, and the eventual development of true human replacement parts, will grow from the convergence of engineering and basic research advances in tissue, matrix, growth factor, stem cell, and developmental biology, as well as materials science and bio informatics. (wikipedia.org)
  • growth
  • 4 . A process according to claim 1 , characterized in that the tissue is one of a type wherein cell proliferation and differentiation is initiated through bio-mechanical transmission of stimuli onto the cytoscleleton and growth or regeneration of tissue can be attained. (google.es)
  • 6 . The process according to claim 5 , further comprising the step of initiating and attaining cell proliferation and differentiation through biomechanical transmission of stimuli onto the cytoskeleton and growth or regeneration of tissue. (google.es)
  • The theoretical principles basic to guided tissue regeneration were developed by Melcher in 1976, who outlined the necessity of excluding unwanted cell lines from healing sites to allow growth of desired tissues. (wikipedia.org)
  • dental
  • The placement of dental implants may also generate the need for guided tissue regeneration. (sacperio.com)
  • All dental prosthesis requires good jaw bone support for it to be successful in the long run. (wikipedia.org)
  • A breakthrough in the use of non-corroding alloys for treating bone fractures prompted Dr Fritz Straumann to enter the fields of orthopedics and dental implantology, which began the second phase of the company's history. (wikipedia.org)
  • Extent
  • No significant difference was observed in the extent of new bone formation between both groups. (uzh.ch)
  • muscle tissue
  • Disuse of the muscles, such as when muscle tissue is immobilized for even a few days of unuse - when the patient has a primary injury such as an immobilized broken bone (set in a cast or immobilized in traction), for example - will also lead rapidly to disuse atrophy. (wikipedia.org)
  • A CT scan can distinguish muscle tissue from other tissues and thereby estimate the amount of muscle tissue in the body. (wikipedia.org)
  • Fast loss of muscle tissue (relative to normal turnover), can be approximated by the amount of urea in the urine. (wikipedia.org)
  • Furthermore, 1 gram of nitrogen is roughly equivalent to 6 gram of protein, and 1 gram of protein is roughly equivalent to 4 gram of muscle tissue. (wikipedia.org)