• N simultaneous continuous-time discrete stochastic processes). (physiology.org)
  • Several statistical pitfalls in the model were discussed: the question of whether the relative risk is constant or evolves with time, the allocation of person years to time periods, the allocation of person years to prevalent cohorts, noncontinuous follow up, continuous and discrete time, and latency and the average time to disease. (cdc.gov)


  • Specifically, we develop a combinatorial method for quantifying the degree of matching between a "reference sequence" of N distinct "letters" (representing a particular target order of firing by N cells) and an arbitrarily long "word" composed of any subset of those letters including repeats (representing the relative time order of spikes in an arbitrary firing pattern). (physiology.org)


  • The importance of taking time factors into consideration in quantitative risk assessments was discussed. (cdc.gov)
  • The author concludes that the risk is not a function of a single time scale but a complex function of multiple time scales which routinely should be addressed in all epidemiological studies. (cdc.gov)


  • In addition, the separate effects of multiple time scales were considered and treated mathematically. (cdc.gov)


  • A carcinogen is assumed to change the rate of transition from one stage to the next so that a single exposure will shorten the time it takes for a neoplasm to appear. (cdc.gov)