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TibetMedicine, Tibetan TraditionalGenomeGenome, BacterialGenome, ViralAltitudeGenome, HumanGenome, PlantGenome, MitochondrialGenome, FungalPhylogenySequence Analysis, DNAAntelopesGenome SizeGenome, ArchaealBuddhismEvolution, MolecularFreshwater BiologyBase SequenceJuniperusGenome, InsectGenome, ProtozoanGenomicsKashin-Beck DiseaseEchinococcus multilocularisGenetic VariationChinaLagomorphaAltitude SicknessHypoxia-Inducible Factor-Proline DioxygenasesGenome, ChloroplastNaphazolineChromosome MappingMolecular Sequence DataSnowEchinococcus granulosusMeteorologyPhylogeographyHistory of MedicineDNA, MitochondrialGenome, HelminthOpen Reading FramesLocusta migratoriaTortureGenome, PlastidSequence AlignmentGeographyMedicine, East Asian TraditionalSyntenyHuman Genome ProjectSpecies SpecificityErigeronThioredoxin Reductase 2Adaptation, PhysiologicalTheftEchinococcosis, HepaticAsian Continental Ancestry GroupDNA, ViralHordeumAcclimatizationEchinococcosisGene OrderSalinityPolymorphism, Single NucleotideComputational BiologyHematologic AgentsModels, GeneticAmino Acid SequenceAster PlantDatabases, GeneticChlamydiaceae InfectionsRecombination, GeneticGenotypeEchinococcosis, PulmonaryMultigene FamilyDNA, BacterialChromosomes, Artificial, BacterialNepalInulaGentianaceaeGene DuplicationEcosystemRepetitive Sequences, Nucleic AcidEthnobotanySelection, GeneticRNA, ViralGenes, ViralGenetics, PopulationSoftwareMolecular Sequence AnnotationGenetic MarkersDNA Transposable ElementsPolymerase Chain ReactionBase CompositionProcollagen-Proline DioxygenaseHaplotypesHistory, AncientSequence Homology, Nucleic AcidMutationCloning, Molecular
PlateauMtDNAPhylogeneticWhole genome dataGenesSequences40,000-year-oldHaplogroupNeanderthalDivergenceBiologyGeneSequencingHaplotypesMolecularRevealAnalysesCompleteMutationalHimalayanDetectionVariantsSequenceNuclearAdaptationSpeciesOriginMarkersIndiaSensitivityBonesAnalysisDataStudyPresentChinaEvolutionAncientHighEntire
Plateau13
  • The Himalayan wolf lineage can be found living in Ladakh in the Himalayas, the Tibetan Plateau, and the mountains of Central Asia predominantly above 4,000 m (13,000 ft) in elevation because it has adapted to a low-oxygen environment, compared with other wolves that are found only at lower elevations. (wikipedia.org)
  • In 2019, a workshop hosted by the IUCN/SSC Canid Specialist Group noted that the Himalayan wolf's distribution included the Himalayan range and the Tibetan Plateau. (wikipedia.org)
  • The Tibetan Plateau (TP) and surrounding regions have one of the most complex biotas on Earth. (nature.com)
  • Fig. 1: Palaeogeographical processes in the Tibetan Plateau and surrounding regions during the Cenozoic. (nature.com)
  • a taeniid cestode from Tibetan fox and plateau pika in China. (cdc.gov)
  • The modern populations of these valleys, who share cultural and linguistic affinities with peoples found today on the Tibetan plateau, are commonly assumed to be the descendants of the earliest inhabitants of the Himalayan arc. (nova.edu)
  • However, this assumption has been challenged by archaeological and osteological evidence suggesting that these valleys may have been originally populated from areas other than the Tibetan plateau, including those at low elevation. (nova.edu)
  • The youngest split in sympatric schizothoracine fish (Cyprinidae) is shaped by ecological adaptations in a Tibetan Plateau glacier lake. (wf-wiki.de)
  • Adaptive Evolution of the Eda Gene and Scales Loss in Schizothoracine Fishes in Response to Uplift of the Tibetan Plateau. (wf-wiki.de)
  • Morphometric and population genomic evidence for species divergence in the Chimarrichthys fish complex of the Tibetan Plateau. (wf-wiki.de)
  • Han, W., Tang, H., Wei, L., Zhang, E. (2023) The first DNA barcode library of Chironomidae from the Tibetan Plateau with an evaluation of the status of the public databases. (chironomidae.net)
  • Introduction Human being cystic and alveolar echinococcosis due to infection using the metacestodes from the tapeworms (sensu stricto) and was lately described in animals (Tibetan fox and plateau pikas varieties within both intermediate and definitive hosts. (biosemiotics2013.org)
  • What came back around the tibetan plateau was P and its decandants. (blogspot.com)
MtDNA5
  • In the past decades, genetic data of mitochondrial DNA (mtDNA) and the non-recombining region of Y-chromosome (NRY) have been widely employed to reconstruct human prehistory [ 9 , 10 ]. (biomedcentral.com)
  • Mitochondrial DNA (mtDNA) encodes essential proteins for oxidative phosphorylation, which is related to aerobic capacity. (genominfo.org)
  • The Canis mtDNA HV1 database contains information about canine mitochondrial DNA HV1 sequences with reconciled annotation. (biomedcentral.com)
  • Some Hindu Indian scientists have used mitochondrial DNA (mtDNA) samples, extracted from the bones of recently discovered ancient skeletal remains of a couple in Rakigarhi in Haryana, to claim the local indigenous origins of all Hindus. (riazhaq.com)
  • Twelve indigenous chicken breeds from Guangdong Province and its adjacent regions were used for mitochondrial DNA (mtDNA) D-loop sequencing, and analyses of genetic distance and genetic relationship between breeds were conducted. (biodiversity-science.net)
Phylogenetic5
  • The mitogenomes provided robust phylogenetic signals that were much more informative than the signals obtained using single mitochondrial genes. (biomedcentral.com)
  • Phylogenetic relationships of glyptosternoid fishes (Siluriformes: Sisoridae) inferred from mitochondrial cytochrome b gene sequences. (wf-wiki.de)
  • Gene is the topic of his studies on Mitochondrial DNA, Phylogenetic tree and Genotype. (research.com)
  • Canine and wolf mitochondrial DNA haplotypes, which can be used for forensic or phylogenetic analyses, have been defined in various schemes depending on the region analyzed. (biomedcentral.com)
  • Phylogenetic analysis involved 13 amino acid sequences and demonstrated that the A. peninsulae genome from BI was more closely grouped with two Korean samples (HQ660074 and JN546584) than the Chinese (KP671850) sample. (accesson.kr)
Whole genome data1
Genes5
  • Two mitochondrial genes that encoding proteins in the oxidative phosphorylation system showed some evidence of adaptive evolution in genus Rhinolophus and the positive selection signals were tested for ND5 in R. philippinensis . (biomedcentral.com)
  • These results indicate that mitochondrial protein-coding genes were targets of adaptive evolution during the evolution of Rhinolophus species, which might have contributed to a diverse range of acoustic adaptations in this genus. (biomedcentral.com)
  • Further findings indicated that one of the genes humans inherited from Denisovans helps modern-day Tibetans survive in high-altitude, low-oxygen environments. (greekreporter.com)
  • This new species can be distinguished from all congeners by significant divergences in the mitochondrial 16S rRNA and CO1 genes and by a combination of morphological characters: small body size, tympanum absent, parotoid glands small and olive-shaped, tarsal fold absent, dorsal body with a fine vertebral line and white nuptial spinules present on dorsal and inner surfaces of fingers I and II in males. (arphahub.com)
  • PosiGene: automated and easy-to-use pipeline for genome-wide detection of positively selected genes. (fish-evol.org)
Sequences3
  • 2021) A new molecular nomenclature for Taenia hydatigena: mitochondrial DNA sequences reveal sufficient diversity suggesting the assignment of major haplotype divisions. (chvst.org.cn)
  • Molecular phylogenetics and phylogeographic structure of Sorex bedfordiae based on mitochondrial and nuclear DNA sequences. (mammal.cn)
  • Here, we report 34 ancient genome sequences, including two from fragmented milk teeth found at the ~31.6 thousand-year-old (kya) Yana RHS site, the earliest and northernmost Pleistocene human remains found. (blogspot.com)
40,000-year-old2
  • With his refined methods, Pääbo managed to sequence a region of mitochondrial DNA from a 40,000-year-old piece of bone. (nobelprize.org)
  • After peering into the genome of a 40,000-year-old bone fragment discovered in Siberia's Denisova Cave in 2008, Pääbo and his fellow researchers discovered an entirely new hominin-the Denisovans. (greekreporter.com)
Haplogroup3
  • Mitochondrial DNA analysis showed high diversity, including some of the older sublineages of M haplogroup and prominent R lineages in all the three tribes. (blogspot.com)
  • To achieve deeper insights into the demographic history of modern humans in East Asia around the Last Glacial Maximum, we extensively analyzed mitochondrial DNA haplogroup M9a'b, a specific haplogroup that was suggested to have some potential for tracing the migration around the Last Glacial Maximum in East Eurasia. (biomedcentral.com)
  • Two of the (unrelated) males from Yana RHS belong to Y-haplogroup P1 and mitochondrial haplogroup U2. (blogspot.com)
Neanderthal4
  • Through his pioneering research, Svante Pääbo accomplished something seemingly impossible: sequencing the genome of the Neanderthal, an extinct relative of present-day humans. (nobelprize.org)
  • Svante Pääbo, a Swedish geneticist and professor who sequenced the Neanderthal genome through his work on human evolution, has been awarded the 2022 Nobel Prize in Physiology or Medicine. (greekreporter.com)
  • After applying these methods to three Neanderthal bones discovered across Europe, Pääbo successfully sequenced the entire Neanderthal genome in 2008. (greekreporter.com)
  • As analyses of the small mitochondrial genome gave only limited information, Pääbo now took on the enormous challenge of sequencing the Neanderthal nuclear genome. (catlearnserv.com)
Divergence1
  • Multiple virus infections in the honey bee and genome divergence of honey bee viruses. (tci-thaijo.org)
Biology3
Gene1
  • To investigate echinococcosis in co-endemic regions three polymerase chain reaction (PCR) assays based on the amplification Favipiravir of a fragment within the NADH dehydrogenase subunit 1 (ND1) mitochondrial gene were optimized for the detection of G1 and DNA derived from parasite tissue or canid fecal samples. (biosemiotics2013.org)
Sequencing10
  • Fifty-nine representative samples were further selected for total mitochondrial DNA sequencing so we could better understand the phylogeny within M9a'b. (biomedcentral.com)
  • METHODS: Whole-genome sequencing was performed on 10 pre-extensively drug-resistant M. tuberculosis strains from different regions of Kazakhstan. (bvsalud.org)
  • Genome sequencing of normal cells reveals developmental lineages and mutational processes. (genomeweb.com)
  • Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity. (genomeweb.com)
  • Exploring genetic variation in the tomato ( Solanum section Lycopersicon) clade by whole-genome sequencing. (genomeweb.com)
  • Variant detection sensitivity and biases in whole genome and exome sequencing. (genomeweb.com)
  • The Marmoset Genome Sequencing and Analysis Consortium. (genomeweb.com)
  • International Wheat Genome Sequencing Consortium (IWGSC). (genomeweb.com)
  • MToolBox: a highly automated pipeline for heteroplasmy annotation and prioritization analysis of human mitochondrial variants in high-throughput sequencing. (genomeweb.com)
  • In this investigation the complete mitochondrial genome sequence for a mouse obtained from Baengnyeong Island (BI) in South Korea was determined using high-throughput whole-genome sequencing for the first time. (accesson.kr)
Haplotypes1
  • The ancient genomes, uniparental haplotypes, and high-altitude adaptive alleles suggest a high-altitude East Asian origin for prehistoric Himalayan populations. (nova.edu)
Molecular2
  • To study the adaptive evidence in the mitochondrial genomes (mitogenomes) of rhinolophids, especially the mitogenomes of the species with low echolocation frequencies, we sequenced eight mitogenomes and used them for comparative studies of molecular phylogeny and adaptive evolution. (biomedcentral.com)
  • Nakao M , McManus DP , Schantz PM , Craig PS , Ito A . A molecular phylogeny of the genus Echinococcus inferred from complete mitochondrial genomes. (cdc.gov)
Reveal1
  • These genomes reveal complex patterns of past population admixture and replacement events throughout northeastern Siberia, with evidence for at least three large-scale human migrations into the region. (blogspot.com)
Analyses1
Complete2
  • The complete mitochondrial genome of Hemibagrus spilopterus (Teleostei: Siluriformes). (wf-wiki.de)
  • In the present study, the complete mitochondrial genome of P. flavomaculatus was sequenced and analyzed. (pensoft.net)
Mutational1
  • Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. (fish-evol.org)
Himalayan2
  • In 2020, more recent research on the Himalayan wolf genome indicates that it warrants species-level recognition under the Unified Species Concept, the Differential Fitness Species Concept, and the Biological Species Concept. (wikipedia.org)
  • One of these wolf, locally called Himalayan wolf (HW) or Tibetan wolf, is found only in the upper Trans-Himalayan region from Himachal Pradesh to Leh in Kasmir and is considered to be C. lupus chanco. (org.in)
Detection1
  • Multiplex MALDI-TOF MS detection of mitochondrial variants in Brazilian patients with hereditary optic neuropathy. (cdc.gov)
Variants2
  • Association of primary open-angle glaucoma with mitochondrial variants and haplogroups common in African Americans. (cdc.gov)
  • Long-term screening for primary mitochondrial DNA variants associated with Leber hereditary optic neuropathy: incidence, penetrance and clinical features. (cdc.gov)
Sequence2
  • A chromosome-based draft sequence of the hexaploid bread wheat ( Triticum aestivum ) genome. (genomeweb.com)
  • Whole-genome sequence analysis reveals differences in population management and selection of European low-input pig breeds. (genomeweb.com)
Nuclear1
  • Nuclear DNA harbors most of the genetic information, while the much smaller mitochondrial genome is present in thousands of copies. (nobelprize.org)
Adaptation1
  • Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA. (genomeweb.com)
Species1
  • A metaanalysis of bat phylogenetics and positive selection based on genomes and transcriptomes from 18 species. (fish-evol.org)
Origin1
  • Zhao E, Yu Q, Zhang N, Kong D, Zhao Y. Mitochondrial DNA diversity and the origin of Chinese indigenous sheep. (opensourcebiology.eu)
Markers2
  • It is distinguished by its genetic markers, with mitochondrial DNA indicating that it is genetically basal to the Holarctic grey wolf, genetically the same wolf as the Tibetan and Mongolian wolf, and has an association with the African wolf (Canis lupaster). (wikipedia.org)
  • Your dog's Wolfiness Score is based on hundreds of markers across the genome where dogs (or almost all of them) are the same, but wolves tend to be different. (embarkvet.com)
India2
  • in 2007 for wolf specimens from the Indian Himalayas that differed in mitochondrial DNA from specimens collected in other parts of India. (wikipedia.org)
  • Elsewhere-Dravidian (in South India), Sino-Tibetan (in China etc. (thuto.org)
Sensitivity1
  • We imported the trimmed mitochondrial reads for each individual with mapping quality >30 into Geneious (version 10.0.9, https://www.geneious.com)68 and reassembled these reads to the reference genome RSRS78, using the Geneious mapper, with medium sensitivity and 5 iterations. (nathalieblanc.fr)
Bones1
  • These included extracting mitochondrial DNA from bones in stringently sanitized rooms prior to applying statistical techniques to weed out remaining genetic contaminants. (greekreporter.com)
Analysis2
  • Comprehensive transcriptomic analysis of Tibetan Schizothoracinae fish Gymnocypris przewalskii reveals how it adapts to a high altitude aquatic. (fish-evol.org)
  • Analysis of 353bp of cytochrome B and 296 bp of d-loop of the mitochondrial genome placed these two individuals in the same lineage of African wolf Canis lupus lupaster identified by Gaubert et al. (canids.org)
Data1
  • This database collects data on the HV1 582 bp region in dog mitochondrial DNA from the GenBank to screen and correct the inconsistencies. (biomedcentral.com)
Study3
  • A total of 837 M9a'b mitochondrial DNAs (583 from the literature, while the remaining 254 were newly collected in this study) pinpointed from over 28,000 subjects residing across East Eurasia were studied here. (biomedcentral.com)
  • In his works, he undertakes multidisciplinary study on Genetics and Mitochondrial DNA. (research.com)
  • Aikio, A. . To investigate the genetic affinities of the sampled individuals, we projected them onto principal components (PC) computed from 1320 modern European and Asian individuals (Fig. AllSaami refers to a grouping including the 2 individuals from the SGDP (Saami(SGDP)) and the high-coverage modern Saami shotgun genome in this study (Modern Saami). (nathalieblanc.fr)
Present2
  • To investigate the peopling and early population history of this dynamic high-altitude contact zone, we sequenced the genomes (0.04×-7.25×, mean 2.16×) and mitochondrial genomes (20.8×-1,311.0×, mean 482.1×) of eight individuals dating to three periods with distinct material culture in the Annapurna Conservation Area (ACA) of Nepal, spanning 3,150-1,250 y before present (yBP). (nova.edu)
  • The mitochondrial genome is small and contains only a fraction of the genetic information in the cell, but it is present in thousands of copies, increasing the chance of success. (nobelprize.org)
China1
  • The Korean field mouse, Apodemus peninsulae mitochondrial genome has previously been reported for mice obtained from mainland Korea and China. (accesson.kr)
Evolution3
  • 2021) Genetic Evolution and Implications of the Mitochondrial Genomes of Two Newly Identified Taenia spp. (chvst.org.cn)
  • Genome of the tropical plant Marchantia inflexa: implications for sex chromosome evolution and dehydration tolerance. (fish-evol.org)
  • Chance and necessity in the genome evolution of endosymbiotic bacteria of insects. (fish-evol.org)
Ancient1
  • By finding rare dogs carrying an ancient variant at a certain marker, we can make associations with behavior, size, metabolism, and development that likely caused these unique signatures of "doggyness" in the genome. (embarkvet.com)
High1
  • Mitochondrial DNA variant associated with Leber hereditary optic neuropathy and high-altitude Tibetans. (cdc.gov)
Entire1