TestisMouse spermatogenesisTesticularFertilityEssential for spermatogenesisFunctions during spermatoDifferentiationMature male gametesMeiosisSpermiogenesisHuman spermatogenesisComplete spermatogenesisMammalian spermatogenesisSpermatogoniaMiceDiploidDrosophilaOogenesisSpermatogenicGametogenesisTestesSpermatozoaAndrogenSteroidogenesisStagesGametesGermSpermatidsMitochondrialAbnormalityHumansRegulationAutophagyStimulateMaleOccursLeydigEpigeneticChromosomesSperm cellsIntratesticularProcessDefectsUndergoResultsTestosterone
Testis16
- Spermatogenesis is the process by which haploid spermatozoa develop from germ cells in the seminiferous tubules of the testis. (wikipedia.org)
- She and colleagues examined 52 transgender women who had bilateral simple orchiectomy and assessed the presence or absence of spermatogenesis in the testis tissue that was removed at the time of surgery. (urologytimes.com)
- In 11.5% of testis specimens, spermatogenesis wasn't reported, according to the study. (urologytimes.com)
- They found no difference in estimated testis volume among testes that did versus didn't have spermatogenesis. (urologytimes.com)
- A more thorough evaluation of the ejaculate may disclose a variety of disturbances originating in the different steps of spermatogenesis and may shed light on disturbed testicular functions or even disclose in the presence of early testis cancer. (biomedcentral.com)
- Biopsies of the testes may be necessary to obtain valid informations about the quality of spermatogenesis or for exclusion of early testis cancer. (biomedcentral.com)
- Within the adult testis, Germ cells (GC) do not express androgen receptor (AR) suggesting androgen-mediated promotion of spermatogenesis must act via AR-expressing somatic cell-types. (biomedcentral.com)
- In the adult testis, Germ cells (GC), do not express AR, and GCs lacking a functional AR mature normally [ 4 ], consequently, androgens are believed to regulate spermatogenesis via androgen-AR signalling in AR-expressing testicular somatic cells. (biomedcentral.com)
- Given the wide-ranging impact of VE function on both the vascular system and peripheral organs, expression of AR within VE cells of the testicular blood vessels would raise the possibility that androgen-mediated modulation of endothelial cell function within the testis contributes to the regulation of spermatogenesis. (biomedcentral.com)
- In otherwise wild-type testes, we find that Lrh1 is dispensable in Leydig cells but is required in Sertoli cells for their proliferation, for seminiferous tubule morphogenesis, for maintenance of the blood-testis barrier, for feedback regulation of androgen production, and for support of spermatogenesis. (umn.edu)
- Effects of a-tocopherol on cadmium-induced toxicity in rat testis and spermatogenesis. (ac.ir)
- Objective To explore the physiological function of gene for cell devision cycle associated 2 ( Cdca2 ), a highly expressed testis gene, in spermatogenesis and fertility in mice. (magtechjournal.com)
- Testis-specific fascin component FSCN3 is dispensable for mouse spermatogenesis and fertility[J]. Mol Biol Rep, 2022, 49: 6261-6268. (magtechjournal.com)
- Mammalian spermatogenesis is a high regulated biological process occurring in the seminiferous tubules in the testis. (intechopen.com)
- Autophagy, an evolutionarily conserved cell reprograming machinery, had been shown to function as an important regulatory mechanism in spermatogenesis and steroid production in testis. (intechopen.com)
- This study designed to investigate the effect of mAM Padministration on histological changes and spermatogenesis indices in the testis of adult male rats.Methods: In this experimental study, 50 male Wistar rats were randomly divided into control (received no treatment, n = 10), vehicle (received saline for 7 and 14 days, n = 20), and experimental group [received mAMP, 5 ml/kg, intraperitoneal (IP) for 7 and 14 days, n = 20]. (iocv.ir)
Mouse spermatogenesis2
- during spermatogenesis suggests that it is involved in the development of the Results levitra for cheap hypercarbia, origin, innovative non-toothed spermatogenesis fossa reserved ablation, amoxicillin buy amblyopia, still, primary, particles all resulted in interleukin (IL) 8 responses and a depletion of intracellular glutathione at diesel exhaust impairs mouse spermatogenesis. (firebaseapp.com)
- Meiotic Knockdown and Complementation Reveals Essential Role of RAD51 in Mouse Spermatogenesis. (nih.gov)
Testicular6
- The bibliometric evaluation suggests that the SEPA has a good exchange of resources in terms of [3] Testicular dygenesis is a condition in which a male has incomplete or complete loss of spermatogenesis, so that the individual produces using biparatopic affibody molecules results in dramatically improved affinity. (firebaseapp.com)
- I sådana Results for testikelatrofi translation from Swedish to English Also, in rats testicular atrophy with decreased spermatogenesis occurred, while in dogs reversible Results and evaluation by the Management Team, Toxicology in vitro 12, spermatogenesis after testicular X irradiation, Journal of Radiation Research, vol. (firebaseapp.com)
- Cellular apoptosis is one of the prominent processes observed in testicular development and normal spermatogenesis. (entomoljournal.com)
- The effects of Pb, Mo, As and Rb on spermatogenesis were investigated by using testicular organ culture of Japanese eel ( Anguilla japonica ). (sfi-cybium.fr)
- In this webinar series "In vivo or in vitro spermatogenesis to restore male fertility", we aim to provide and discuss several procedures to restore male fertility using in vivo or in vitro spermatogenesis using immature testicular tissue. (eshre.eu)
- The participants will get an update and overview on in vivo and in vitro spermatogenesis for restoring male fertility mainly using immature testicular tissue. (eshre.eu)
Fertility11
- Our finding that about a third of patients had some evidence of spermatogenesis in the testes at the time of bilateral simple orchiectomy indicates that there is at least some fertility potential in these patients,' says Tristan Nicholson, MD, PhD. (urologytimes.com)
- It seems that the noise stress has negative influences on the fertility of male based on enhancing of the apoptotic process induced by pathogenesis stress and suppressing the kinetics spermatogenesis. (scialert.net)
- Identification of the border line between normal and disturbed spermatogenesis substantiate the diagnosis of impaired male fertility. (biomedcentral.com)
- however, no significant differences in bodyweight or reproductive tissue weights could be detected in VEARKO animals and spermatogenesis and fertility was unaffected. (biomedcentral.com)
- We demonstrate the successful generation and empirical validation of a cell-specific knockout of AR from VE cells, and conclude that AR expression in VE cells is not essential for spermatogenesis or male fertility. (biomedcentral.com)
- We then exploited a conditional gene targeting approach to specifically ablate AR from endothelial cells of the vascular system to examine the impact of perturbed endothelial AR-signalling on spermatogenesis and male fertility. (biomedcentral.com)
- Unexpectedly, however, over time the Lrh1 mutant germ line recovered abundant spermatogenesis and fertility. (umn.edu)
- CDCA2 deletion in mice had no statistically significant effect on spermatogenic cells, sperm motility parameters and male fertility at all stages of spermatogenesis. (magtechjournal.com)
- Conclusions Cdca2 is probably not necessary for spermatogenesis and male fertility maintenance in mice. (magtechjournal.com)
- Gene Cdca2 knockout has no significant effect on spermatogenesis and fertility in mice[J]. Basic & Clinical Medicine, 2023, 43(5): 717-723. (magtechjournal.com)
- Several studies have shown that mAMP has inhibitory effects on oogenesis and spermatogenesis, and causes impaired fertility. (iocv.ir)
Essential for spermatogenesis1
- We described two tightly linked and nearly identical homeobox genes of the TGIF (TG-interacting factor)subclass called vismay and achintya that are essential for spermatogenesis in Drosophila . (biologists.com)
Functions during spermato1
- This breakthrough has set the foundation for our ongoing multi-omics approach, incorporating single-cell RNA-seq, ATAC-seq, and other NGS techniques to assess the epigenetic landscape in humanized germ cells and perform a comprehensive analysis of CTCFL functions during spermatogenesis. (nih.gov)
Differentiation5
- Spermatogenesis involves precise temporal and spatial gene expression and cell signalling to reach a coordinated balance between self-renewal and differentiation of spermatogonial stem cells through various germ cell states including mitosis, and meiosis I and II, which result in the generation of haploid cells with a unique genetic identity. (nih.gov)
- The genetic analysis of spermatogenesis in Drosophila melanogaster has led to the identification of several genes that control the onset of meiosis, spermatid differentiation, or both. (biologists.com)
- In flies deficient for both genes,spermatogenesis is blocked prior to any spermatid differentiation and before the first meiotic division. (biologists.com)
- Throughout spermatogenesis multiplication, maturation and differentiation of germ cells results in the formation of the male gamete. (biomedcentral.com)
- Spermatogenesis indices which include: tubular differentiation index (TDI), spermiogenesis index (SI), repopulation index (RI) and the mean seminiferous tubules diameter (MSTD) were studied. (iocv.ir)
Mature male gametes3
- Spermatogenesis produces mature male gametes, commonly called sperm but more specifically known as spermatozoa, which are able to fertilize the counterpart female gamete, the oocyte, during conception to produce a single-celled individual known as a zygote. (wikipedia.org)
- The significance of spermatogenesis is that it releases mature male gametes. (vedantu.com)
- The products of spermatogenesis are the mature male gametes, namely the spermatozoa. (biomedcentral.com)
Meiosis3
- In spermatogenesis, meiosis results in the formation of. (firebaseapp.com)
- How are mitosis and meiosis involved in spermatogenesis? (profound-answers.com)
- Expression of the Hspa2-Cre transgene during meiosis in male germ cells makes these mice a useful tool for defining the roles of genes expressed at different times during spermatogenesis or expressed in spermatogenic cells. (nih.gov)
Spermiogenesis1
- Multiple approaches to study human in vitro spermatogenesis have been proposed, but technical and ethical obstacles have limited the ability to complete spermiogenesis, and further work is needed to establish a robust culture system for clinical application. (nih.gov)
Human spermatogenesis3
- Various clinical cases illustrate the roles of T in human spermatogenesis. (nih.gov)
- However, the sophisticated transcriptional networks of autophagic genes throughout human spermatogenesis and their biological significance remain largely uncharacterized. (thno.org)
- We profiled the transcriptional signatures of autophagy-related genes during human spermatogenesis by assessing specimens from nine fertile controls (including two normal persons and seven obstructive azoospermia (OA) patients) and one nonobstructive azoospermia (NOA) patient using single-cell RNA sequencing (scRNA-seq) analysis. (thno.org)
Complete spermatogenesis2
- This finding indicates that severe germ line depletion triggers a response allowing mutant spermatogonia to recover the ability to undergo complete spermatogenesis. (umn.edu)
- four 16-day cycles are needed to complete spermatogenesis. (profound-answers.com)
Mammalian spermatogenesis2
- This is essential because mammalian spermatogenesis is a complex process that requires precise homeostasis of different cell types. (entomoljournal.com)
- Elucidation GI 254023X from the function of LM23 may promote understanding into mammalian spermatogenesis. (himafund.org)
Spermatogonia2
- In the germ line we found that Lrh1 is required for maintenance of functional spermatogonia, and hence mutants progressively lose spermatogenesis. (umn.edu)
- Spermatogenesis was also divided into five stages: spermatogonia, primary spermatocyte , secondary spermatocyte, spermatids and spermatozoa. (thefreedictionary.com)
Mice3
- Autophagy has been implicated as a crucial component in spermatogenesis, and autophagy dysfunction can lead to reproductive disorders in animal models, including yeast, C. elegans and mice. (thno.org)
- Transcriptional regula-tion of P63 on the apoptosis of male germ cells and three stages of spermatogenesis in mice[J]. Cell Death Dis, 2018, 9: 76. (magtechjournal.com)
- Effect of Pabpc6 knockout on spermatogenesis of male mice [J]. Basic & Clinical Medicine, 2023, 43(4): 560-567. (magtechjournal.com)
Diploid3
- During spermatogenesis, a diploid spermatogonium (male germ cell) increases its size to form a diploid primary spermatocyte. (firebaseapp.com)
- Which of the following cells in spermatogenesis is diploid? (profound-answers.com)
- They begin the process of spermatogenesis when they divide by mitosis to produce cells called primary spermatocytes, which are also diploid cells….A Seminiferous Tubule. (profound-answers.com)
Drosophila1
- In 2-year chronic oral rat studies, a dose-related reduction of spermatogenesis and decreased organ weights In Drosophila cell culture, dmfrn overexpression resulted in an overestimation of connection between the mitochondrial iron metabolism and spermatogenesis. (firebaseapp.com)
Oogenesis8
- Thus, spermatogenesis is the male version of gametogenesis, of which the female equivalent is oogenesis. (wikipedia.org)
- In the male, the production of mature sperm cells, or spermatogenesis, results in four haploid gametes, whereas, in the female, the production of a mature egg cell, oogenesis, results in just one mature gamete. (profound-answers.com)
- What is spermatogenesis and oogenesis? (profound-answers.com)
- The production of sperm is called spermatogenesis and the production of eggs is called oogenesis. (profound-answers.com)
- What's the difference between spermatogenesis and oogenesis? (profound-answers.com)
- Differences Between Spermatogenesis and Oogenesis. (profound-answers.com)
- As its name suggests, oogenesis is the opposite of spermatogenesis-oogenesis is the process of forming the egg, the female gamete. (profound-answers.com)
- Unlike spermatogenesis that occurs in the seminiferous tubule, oogenesis occurs in the ovaries of the female reproductive organ. (profound-answers.com)
Spermatogenic1
- S. Yokota and Y. Onohara, "Expression and Localization of NANOS1 in Spermatogenic Cells during Spermatogenesis in Rat," CellBio , Vol. 2 No. 1, 2013, pp. 1-10. (scirp.org)
Gametogenesis1
- We call gametogenesis in the male spermatogenesis and it produces spermatozoa. (firebaseapp.com)
Testes5
- The location [Testes/Scrotum] is specifically important as the process of spermatogenesis requires a lower temperature to produce viable sperm, specifically 1°-8 °C lower than normal body temperature of 37 °C (98.6 °F). Clinically, small fluctuations in temperature such as from an athletic support strap, causes no impairment in sperm viability or count. (wikipedia.org)
- spermatogenesis , the origin and development of the sperm cells within the male reproductive organs, the testes . (britannica.com)
- The position of the testes or scrotum is crucial because spermatogenesis requires a lower temperature than the normal body temperature of 37 °C (98.6 °F) in order to obtain viable sperm cells. (vedantu.com)
- Because Vismay and Achintya are likely to be sequence-specific DNA binding factors, these results suggest that they help to specify the spermatogenesis program by recruiting or stabilizing Always early and Cookie monster to specific target genes that need to be transcriptionally regulated during testes development. (biologists.com)
- Spermatogenesis is the production of sperm from the primordial germ cells within the male reproductive organs, the testes. (profound-answers.com)
Spermatozoa1
- Spermatogenesis starts in the bottom part of seminiferous tubes and, progressively, cells go deeper into tubes and moving along it until mature spermatozoa reaches the lumen, where mature spermatozoa are deposited. (wikipedia.org)
Androgen1
- In this study, we have used a similar approach to specifically ablate AR-signalling from Vascular Endothelial (VE) cells, with a view to defining the significance of androgen signalling within this cell-type on spermatogenesis. (biomedcentral.com)
Steroidogenesis1
- Arsenic may inhibit steroidogenesis and spermatogenesis. (greenmedinfo.com)
Stages5
- The entire process of spermatogenesis can be broken up into several distinct stages, each corresponding to a particular type of cell in humans. (wikipedia.org)
- Let us study the spermatogenesis process stages while we describe the process of spermatogenesis. (vedantu.com)
- The entire spermatogenesis steps can be divided up into multiple stages, each of which corresponds to a different cell type in humans. (vedantu.com)
- Spermatocytogenesis is the first one amongst the spermatogenesis process stages, and seems to be the male form of gametocytogenesis, in which spermatocytes with half the regular complement of genetic material are produced. (vedantu.com)
- The present paper covers one of the late stages of spermatogenesis. (rupress.org)
Gametes4
- How many of the cells produced in spermatogenesis are functional gametes? (profound-answers.com)
- How many gametes are produced by spermatogenesis? (profound-answers.com)
- Spermatogenesis produces how many gametes? (profound-answers.com)
- Spermatogenesis produces 4 gametes. (profound-answers.com)
Germ5
- The understanding of spermatogenesis needs detailed informations about the organization of the germinal epithelium, the structure and function of different types of germ cells, endocrine and paracrine cells and mechanisms, intratesticular and extratesticular regulation of spermatogenesis. (biomedcentral.com)
- The profound knowledge of the complicate process of spermatogenesis and all cells or cell systems involved with is the prerequisite to develop concepts for therapy of male infertility or to handle germ cells in the management of assisted reproduction. (biomedcentral.com)
- The complete process of germ cell development is called spermatogenesis. (biomedcentral.com)
- Spermatogenesis is the process of the production of sperms from the immature germ cells in males. (firebaseapp.com)
- Treatment with these trace elements together with 11-ketotestosterone (KT) significantly inhibited KT-induced germ cells proliferation, suggesting that Mo, Rb, Pb and As directly interrupt KT-induced spermatogenesis. (sfi-cybium.fr)
Spermatids1
- While the spermatogenesis process, spermatids tend to appear in a tail by developing microtubules under one of the centrioles, which eventually becomes the basal body. (vedantu.com)
Mitochondrial1
- U. v. microspectrophotometric results exhibited no First evidence of paternal transgenerational effects in amphibians (Xenopus t.) to the anti-androgenic pesticide linuron altered spermatogenesis and impaired mitochondrial iron homeostasis and its impact in different cellular processes such as cell proliferation and spermatogenesis. (firebaseapp.com)
Abnormality2
- Deletion of HYLS1 led to sensory cilia dysfunction and spermatogenesis abnormality. (elsevierpure.com)
- Defects in epigenetic patterns may increase the risk of abnormal spermatogenesis, fertilisation failure, early embryogenesis abnormality and several other complications during pregnancy. (oncotarget.com)
Humans4
- In humans, chromosomal abnormalities arising from incorrect spermatogenesis results in congenital defects and abnormal birth defects (Down syndrome, Klinefelter syndrome) and in most cases, spontaneous abortion of the developing foetus. (wikipedia.org)
- For humans, the entire process of spermatogenesis is variously estimated as taking 74 days (according to tritium-labelled biopsies) and approximately 120 days (according to DNA clock measurements). (wikipedia.org)
- In humans, spermatogenesis starts at the beginning of puberty and lasts lifelong. (nih.gov)
- The whole spermatogenesis process in humans is predicted to take place between 74 days (as per tritium-labeled biopsies) and 120 days (according to DNA clock measurements). (vedantu.com)
Regulation1
- Mapping epigenetic modifications and identifying their roles in the regulation of spermatogenesis and embryogenesis are essential for gaining fundamental medical understandings and for clinical applications. (oncotarget.com)
Autophagy1
- Gene knockdown was used to identify the role of Cst3 in autophagy during spermatogenesis. (thno.org)
Stimulate1
- Stimulate spermatogenesis. (medscape.com)
Male4
- Spermatogenesis takes place within several structures of the male reproductive system. (wikipedia.org)
- Spermatogenesis occurs in several systems inside the male reproductive system. (vedantu.com)
- Where does spermatogenesis occur in the male body? (profound-answers.com)
- The effect of retinoids on spermatogenesis in adult male gerbils [Gerbillus cheesemani] was studied using light and electron microscopy. (who.int)
Occurs2
- During the process of spermatogenesis, significant epigenetic reprogramming occurs in the genome. (nih.gov)
- Spermatogenesis: An Overview mole occurs due to an abnormal conception, that results in no baby being formed and hence an early pregnancy loss. (firebaseapp.com)
Leydig2
- Spermatogenesis depends from intratesticular and extratesticular hormonal regulatory processes and functions of the intertubular microvasculature, the Leydig cells and other cellular components of the intertubular space. (biomedcentral.com)
- It was found that 13-cis-retinoic acid induced almost complete cessation of spermatogenesis and produced alterations in the cytoplasm of Leydig cells. (who.int)
Epigenetic2
- Meiotic sex chromosome inactivation (MSCI) is an essential epigenetic process, which transcriptionally silences X and Y chromosomes during spermatogenesis. (cuni.cz)
- More and more evidence has shown that specific epigenetic modifications are established during spermatogenesis, which will be transferred into oocyte via fertilisation, and play an important role in the early embryo development. (oncotarget.com)
Chromosomes1
- Previous studies in hybrids detected multiple abnormalities of spermatogenesis and a high frequency of dissociation between the X and Y chromosomes at the meiotic prophase. (mdpi.com)
Sperm cells1
- How many sperm cells are made by the end of spermatogenesis? (profound-answers.com)
Intratesticular1
- This example shows that intratesticular T plays a major role in spermatogenesis. (nih.gov)
Process4
- Spermatogenesis is highly dependent upon optimal conditions for the process to occur correctly, and is essential for sexual reproduction. (wikipedia.org)
- Spermatogenesis is defined as the process by which sperms are produced. (profound-answers.com)
- Sperms are produced by a process known as spermatogenesis. (profound-answers.com)
- The process of sperm cell development is known as spermatogenesis. (profound-answers.com)
Defects1
- Yet, the standard evaluation of the ejaculate does not provide in many cases sufficient information about the defects of spermatogenesis. (biomedcentral.com)
Undergo1
- More than one-third of transgender women on gender-affirming hormone therapy have some or intact spermatogenesis when they're about to undergo bilateral simple orchiectomy, according to research presented at the AUA annual meeting in Chicago. (urologytimes.com)
Results3
- The results showed decreased solubility of HSF1 and HSF2 during oxidative stress, of Oncomir-1, targets heat shock transcription factor 2 in spermatogenesis. (firebaseapp.com)
- a dose-related reduction of spermatogenesis and decreased organ av P Umate · 2011 · Citerat av 90 - Results. (firebaseapp.com)
- Moreover, results showed a significant decrease in spermatogenesis indices including TDI, SI, RI, and MSTD in 14th day, compared to control group (P (iocv.ir)
Testosterone1
- However, testosterone stimulates spermatogenesis. (apollo247.com)