• Single cells and organisms may adapt to harmful oxidative stress conditions, through stress-activated factors. (springer.com)
  • generated positive changes, producing a decrease in pro-inflammatory states, oxidative stress, and aging. (bvsalud.org)
  • Nrf2 is a master eukaryotic redox-active factor and belongs to Cap 'n' Collar (Cnc)-bZIP (basic leucine zipper) family of transcription factors. (springer.com)
  • Finally, we show that LIF increases the expression of the core transcription factors: Klf4, Fbx15, Nanog, Sox2 and c-Myc. (karger.com)
  • Interestingly, differential DNA methylation was related to several transcription factors and proteins with DNA binding domains, which implies direct effects of these DNA methylation changes on gene expression. (medscape.com)
  • Time-series intervention analyses of monthly aggregations of hospitalization for acute and chronic causes among men and women aged 15-39, 40-49, 50-69 and more than 69 years. (nih.gov)
  • After the price reduction the chronic hospitalization rate for men increased among those below age 70 years. (nih.gov)
  • It was largest among those aged 50-69 years: 22%, which implies an increase of 18.0 monthly hospitalizations per 100,000 person-years, and there was an 11% and 16% (11.5 and 4.8 monthly hospitalizations) increase among those aged 40-49 and 15-39, respectively. (nih.gov)
  • Acute hospitalizations increased by 17% and 20% (6.2 and 7.0 per month) among men aged 40-49 and 50-69 years, respectively, and by 38% among women aged 50-69 years (2.3 per month). (nih.gov)
  • Afrikaners have good fertility, and can continue to calve over the age of 16 years, with records showing cows calving at 21. (wikipedia.org)
  • For many years, Borderline personality disorder was considered a mental illness only associated with adults above age 18, however in recent years mental health professionals have begun to consider the possibility of Borderline Personality Disorder being diagnosed in adolescents. (bartleby.com)
  • 2 years of age are frequently infected in theses areas in community ( 1 - 4 ) and hospital ( 5 ) settings. (cdc.gov)
  • BACKGROUND: To describe patterns and correlates of tobacco product use other than cigarettes in adolescents 12-17 years of age. (who.int)
  • Participants included 45 typically developing participants, nine in each of five age categories: 16-18 years, 21-25 years, 48-55 years, 65-72 years and 85-90 years. (abainternational.org)
  • Thus, the cognitive functions that are essential for learning undergo considerable development between the ages of 6 and 10 years, and further brain changes occur during adolescence. (plos.org)
  • Here, in a prospective cohort study (the BREATHE study), the researchers assess whether exposure of children aged 7-10 years to traffic-related air pollutants in schools in Barcelona, Spain, is associated with impaired cognitive development. (plos.org)
  • Study participants aged 6+ years from of NHANES 2001 - 2002 with stored urine. (cdc.gov)
  • Experiments evaluating storage at -70°C for greater than 2 years indicate no changes in urinary levels of perchlorate, thiocyanate and nitrate. (cdc.gov)
  • Ten gay elder men, at the average age of 65.7 years participated of it (SD = 3.86). (bvsalud.org)
  • Within the Brazilian context, an IBGE - Brazilian Institute of Geography and Statistics - (2016) research indicated the real aging of the country, which will reach 30.2 million Brazilians aging more than 60 years. (bvsalud.org)
  • The study population included 11,985 adults (aged 18 years) diagnosed with active TB from January 1, 2015 through December 31, 2019, and 1,849,820 adults tested for HCV antibodies between January 1, 2015 and September 30, 2020, who were not diagnosed with TB during that time. (cdc.gov)
  • Different kinds of aggregates and asphalt binders (unaged, short and long term aged) were selected to analyze the factors influencing their adhesion fatigue performance. (hindawi.com)
  • The raw bioassays you want to analyze in this experiment. (lu.se)
  • During the forced work-from-home experiment of 2020, many organizations embraced video as a primary enabler of company culture and employee engagement. (ringcentral.com)
  • Gender and age differences have been found across studies focusing on attitudes toward robots in general. (degruyter.com)
  • Adult age differences in the ability to read and remember metaphor, Educ Gerontol, 17(4), 297-313. (frontiersin.org)
  • Age differences in prefontal recruitment during verbal working memory maintenance depend on memory load. (frontiersin.org)
  • Increasing aging time resulted in less stable lean color although these differences were small and muscle dependent. (usda.gov)
  • After correcting for differences in age, time since death, brain pH, and other conditions such as depressive disorder and alcohol use disorder, the researchers observed that cells in BA9 appeared biologically older in the men who had CUD. (medscape.com)
  • Alternatively, if the kinetic processes influenc- out adjustment for the kinetic differences in particle ing particle disposition in the lungs of humans and ro- clearance and retention, would be inadequate for pre- dents are not related by a standard scaling factor (e.g. (cdc.gov)
  • There is good evidence that only a few animal researchers are aware of the many ways in which their experiments can be biased (Reichlin et al 2016) and that only a few researchers take steps to minimise the possibility of these biases (Kilkenny et al 2009). (safermedicines.org)
  • By around 2050, it is expected that, for the first time, there will be more elderly people than children aged below 15, causing elderly population to reach 2 billion people, or 22% of the world population (Instituto Brasileiro de Geografia Estatística - IBGE, 2016). (bvsalud.org)
  • However, to our knowledge no previous study has focused on the psychological factors underlying attitudes toward sex robots. (degruyter.com)
  • The predictable age of onset and existence of rare outliers provides researchers a valuable opportunity to study genetic variation linked to the age of Alzheimer's onset. (sflorg.com)
  • In this study, we contribute to understanding how underlying genetics associate with age of onset in individuals with dominant Alzheimer's. (sflorg.com)
  • The results of the largest study to date looking at genetic modifiers of the age of onset of dementia were recently published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association . (sflorg.com)
  • Find out how they did it and how their work might contribute to the study of aging. (nyas.org)
  • This study investigated chronological age as an independent variable that correlates with overselectivity in typically developing participants. (abainternational.org)
  • Some studies indicate that vaccine hesitancy among the Black population is due to a well-founded mistrust of health care institutions predicated on contemporary and historical medical racism (6,11), a form of racism perpetuated by health care practices, teachings, and norms that include US government-sanctioned experiments on members of the Black population (eg, the Tuskegee Syphilis Study) and discriminatory patient-provider encounters. (cdc.gov)
  • Perchlorate, nitrate and thiocyanate were measured in all available urine samples from one of the environmental 1/3 subsets of study participants ages 6 and older in NHANES 2001 - 2002. (cdc.gov)
  • In a novel study of postmortem brain tissue, "we detected a trend towards stronger biological aging of the brain in individuals with cocaine use disorder compared to individuals without cocaine use disorder," lead investigator Stephanie Witt, PhD, Central Institute of Mental Health, Mannheim, Germany, said in a news release. (medscape.com)
  • Witt said it was also "fascinating that among those genes that showed the strongest changes in DNA methylation levels in our study, two genes were previously reported to regulate behavioral aspects of cocaine intake in rodent experiments. (medscape.com)
  • This study aimed at analyzing social representations of Brazilian gay men concerning male aging, homosexuality and homophobia. (bvsalud.org)
  • The main limitation of this study was that due to the reliance on existing electronic databases, we were unable to account for the impact of all confounding factors in some of the analyses. (cdc.gov)
  • and (3) An analysis between instructional methodologies-eclectic versus behavioral-on the remediating factor for stimulus overselectivity. (abainternational.org)
  • The prevalence of replicating pancreatic β-cells declines dramatically with age in both rodents and humans ( 4 , 5 ). (diabetesjournals.org)
  • General slowing in semantic priming and word recognition, Psychology and Aging, 7, 257-270. (frontiersin.org)
  • We also shed light on the psychological factors influencing attitudes toward sex robots, including disgust sensitivity and interest in science fiction. (degruyter.com)
  • Using patterns of DNA methylation as a measure of the biological age of cells, a total of 20 differentially methylated regions were significantly associated with CUD status after multiple testing correction. (medscape.com)
  • However, she cautioned that because biological age estimation is "a very recent concept in addiction research and is influenced by many factors, further studies are required to investigate this phenomenon, with larger sample sizes than were possible here. (medscape.com)
  • related chemical compounds, physical agents (such as radiation) and biological factors (such as viruses). (who.int)
  • pThe mechanical behavior of acrylonitrile butadiene copolymer (NBR)-organomodified layered silicate (nanoclay) was modeled using design of experiments approach. (amrita.edu)
  • ORH should be integrated into primary health care programmes by building policies suited to each country and based on the common risk factor approach. (who.int)
  • In most countries, populations of very effectively established an agenda for a pri- young and school-age children receive mary health care approach based on practi- considerable benefit from preventive health cal, scientifically sound and socially measures such as vaccinations and exami- accepted methods and technology. (who.int)
  • For example, some students may decide there are only four potentially important factors and setup a 2 4 full factorial. (isixsigma.com)
  • Both factors potentially affect hiring practices of firms. (bfh.ch)
  • The frequency of pancreatic β-cell replication declines dramatically with age, potentially contributing to the increased risk of type 2 diabetes in old age. (diabetesjournals.org)
  • Analysis of risk factors did not show associations with specific Cryptosporidium spp. (cdc.gov)
  • Characterization of the aging process is accomplished by mass spectral analysis, factor analysis-based descriptions such as positive matrix factorization, and optical properties. (psi.ch)
  • Experiments are the starting point for analysis. (lu.se)
  • To be able to use the values of the experimental factors in the analysis of your data the values must be accessible from the raw bioassays. (lu.se)
  • In the risk factor analysis adjusted for age, sex, and case definition (new versus previously treated), multidrug-resistant (MDR) TB was associated with an increased risk of LTFU after a positive HCV antibody test (adjusted risk ratio [aRR] = 1.41, 95% CI [1.12, 1.76], p = 0.003). (cdc.gov)
  • According to the United Nations, the proportion of people aged over 65 now outnumber children younger than 5. (fightaging.org)
  • At the same time, those who abuse drugs and alcohol at a younger age are also more likely to develop an addiction later in life. (drugrehab.com)
  • Although younger people are often reluctant to view older people as sexually interested, most older people remain interested in sex and report satisfying sex lives well into old age. (msdmanuals.com)
  • Agents differed in wearing face masks and age (young, elderly). (nature.com)
  • The enormous growth in the elderly population is posing a socioeconomic challenge to societies worldwide, and necessitates new sweeping interventions for age-associated diseases. (fightaging.org)
  • The decline mirrors a national trend, but new figures from the U.S. Centers for Disease Control and Prevention show Utah's decrease is more pronounced since birthrates reached a peak in 2007 - a phenomenon that may be an outgrowth of a change in the age of Mormon missionary service. (culteducation.com)
  • Previous studies have shown the involvement of cell-autonomous factors in this phenomenon, particularly the decline of polycomb genes and accumulation of p16/INK4A. (diabetesjournals.org)
  • As a worldwide phenomenon, aging causes changes in various contexts of society. (bvsalud.org)
  • Aging is a phenomenon that is common to all individuals, but it occurs idiosyncratically to each one, being influenced by biopsychosocial surroundings (Neri, 2014). (bvsalud.org)
  • Scientists think active bodies could mean improved mental focus, better decision making, faster healing time for patients with nerve or brain injuries, and reduced risk of dementia as we age. (sciencebuddies.org)
  • The effects of aging on the adhesion fatigue performance are different for PG64-22 and rubber asphalt. (hindawi.com)
  • As shown in the figure, short-term and long-term aging have significant effects on the modulus of PG64-22, while less effect for aging is found on the modulus of rubber asphalt. (hindawi.com)
  • For the subjects of real-life brainwashing experiments, the effects could be traumatic and far-reaching. (peoplesworld.org)
  • Although the effectiveness of aging in improving tenderness is well documented, the effects of aging on other economically important traits are not well understood. (usda.gov)
  • This experiment was conducted to evaluate the effects of extended postmortem aging in Ribeye and top sirloin steaks from carcasses with Low Small or Upper Slight marbling scores. (usda.gov)
  • Here we decouple source and processing effects through experiments on aerosol formation and aging using model compounds (e.g. glyoxal and alpha-pinene), selected sources (e.g. vehicle and cooking emissions), and ambient particles. (psi.ch)
  • Linear mixed effects models were adjusted for age, sex, maternal education, socioeconomic status, and air pollution exposure at home. (plos.org)
  • However, the distinction and relationship between wider determinants operating at the societal and economic levels and behavioural factors affecting people's health-related decision-making in smaller and more specific contexts is not well documented, in spite of the fact that both perspectives are complementary and necessary to achieve better health outcomes and reduce inequities. (who.int)
  • personal factors such as age and gender were the most widely studied. (cdc.gov)
  • Environmental factors and genetics are known to be the cause of BPD. (bartleby.com)
  • 9000 job applications, varying job candidate's personal characteristics such as marital status and age of children. (bfh.ch)
  • the focus areas of their research had print resources for children ages 0 through 18. (wikipedia.org)
  • Experiment 1 compared three groups of 12 children with high, moderate, and low-functioning autism. (abainternational.org)
  • However, although many schools are located next to busy roads and although traffic-related air pollution levels peak during school hours, it is not known whether exposure of school-age children to traffic-related air pollutants impairs their cognitive development and thus their ability to learn. (plos.org)
  • The toxicity depends on a variety of factors: dose, duration and route of exposure (see Module Two ), shape and structure of the chemical itself, and individual human factors. (cdc.gov)
  • With the recent discovery that adult olfactory bulb neurogenesis in the human brain likely ceases after 18 months of age, there is increased interest in studying the NPs of the neonate [ 1 ]. (karger.com)
  • Bellegarrigue NA, Velásquez factor, and sirtuin enzyme pathways are considered, generating a neuroprotective effect. (bvsalud.org)
  • Strip loin and top sirloin subprimals from each carcass side were assigned to aging treatments (14, 21, 28, or 35 d) in an incomplete block arrangement. (usda.gov)
  • Experiment results show that asphalt has more important effect on the adhesion performance comparing with aggregate. (hindawi.com)
  • There is nothing more exciting than planning an experiment and getting the results," Arnon told The Jerusalem Post. (jpost.com)
  • What results do you think you would get if you tried this experiment? (sciencebuddies.org)
  • RESULTS: Only 3% of adolescents who never smoked cigarettes experimented with other tobacco products. (who.int)
  • Results indicate that increasing aging time decreased color life of beef muscles, and that marbling class had minimal impact on lean color stability. (usda.gov)
  • Combining real-world sources with controlled processing conditions leads to an increased process-level understanding of organic aerosol aging and enhanced interpretation of the results from existing source apportionment techniques. (psi.ch)
  • Cochran, along with collaborators from HudsonAlpha, the University of California, Santa Barbara, University of Miami, Columbia University, Universidad de Antioquia, Icahn School of Medicine at Mt. Sinai, and Washington University in St. Louis analyzed the genomes of 340 individuals from the Antioquia family as well as similar families from other studies to gain insight into the genetic landscape of age of disease onset. (sflorg.com)
  • Much less is known on the effect of aging in pragmatic processing, which has been studied mainly in relation with two typical pragmatic processes: the turn-taking system (Murphy et al. (frontiersin.org)
  • Reactive conditions simulating atmospheric oxidation processes are controlled in parallel experiments using a stationary smogchamber, mobile smogchamber, and portable flow reactor. (psi.ch)
  • cal factors influencing these processes. (cdc.gov)
  • One promising hit was a new variant near the gene CLU, previously implicated as a genetic risk factor for late-onset Alzheimer's disease, and two other top candidate variants also might affect CLU-related biology. (sflorg.com)
  • Typically the value of an experimental factor is varied between samples or group of samples. (lu.se)
  • The company wants you to design an experiment that will identify the direct marketing process that maximizes the number of customers they can acquire. (isixsigma.com)
  • How does exercise influence the aging process? (sciencebuddies.org)
  • This year we have an incredibly exciting program with global thought-leaders sharing their latest insights into aging and how we target aging process ensuring everyone lives a healthier and longer life. (fightaging.org)
  • It aims to prevent and reverse diseases of aging by addressing their common root cause, the aging process itself. (fightaging.org)
  • Torontonians are going to weird new lengths to cheat the aging process (and score model-worthy facial features) without going under the knife. (torontolife.com)
  • At this age they tend to explore their surroundings to experiment, learn, and "see for themselves. (bartleby.com)
  • Other factors tend to include language and geography, as some areas lack access to bookstores or public or community school libraries that would provide books. (wikipedia.org)
  • Les participants à l'enquête ont affirmé passer en moyenne 71,07 minutes par jour (ET 72,1) à jouer à des jeux vidéo sur ordinateur ou sur console. (who.int)
  • encoded by Nfe2l2 gene) is a transcription factor responsible for the regulation of cellular redox balance and protective antioxidant and phase II detoxification responses in mammals [ 1 , 2 ]. (springer.com)
  • This regulation is sive loss of neurons and white matter that believed to positively impact these diseases can lead to brain atrophy and different by promoting normal aging and delaying types of disability. (bvsalud.org)
  • When it comes to mastering design of experiments (DOE) , many quality professionals experience a steep learning curve. (isixsigma.com)
  • After the trainees create their experimental design, they are ready to perform the experiment. (isixsigma.com)
  • A Box-Behnken design with three factors and three levels was used to model the relationship between properties of NBR nanocomposites and the ingredients. (amrita.edu)
  • Looking for a quick way to design experiments? (qiagen.com)
  • An explanation of the experiment design. (lu.se)
  • Postmortem aging is widely used to ensure tenderness of beef cuts. (usda.gov)
  • We are delighted to announce the fifth Ending Age-Related Diseases conference on August 11-14, 2022! (fightaging.org)
  • Introduction The language ability is known to decline across the life span and it has been shown that aging in healthy speakers compromises language comprehension in three main aspects: processing speed, inhibition of irrelevant information and working memory (Myerson et al. (frontiersin.org)
  • In the psycholinguistic literature, the decline of language ability with aging has been studied at the syntactic, phonological and semantic level. (frontiersin.org)
  • We conclude that systemic factors contribute to the replicative decline of old pancreatic β-cells. (diabetesjournals.org)
  • Another group may decide they need to explore all seven factors and setup a 2 7-3 fractional factorial. (isixsigma.com)
  • Most of the best conferences relating to aging research, and the longevity industry that has emerged from that research, feature an even mix of entrepreneurs, scientists, and investors. (fightaging.org)
  • There were four major types of investigations including cross sectional surveys, longitudinal studies, laboratory experiments, and field studies. (cdc.gov)
  • It is expected that data can contribute to new investigations and reflections on the aging of homosexual people, bringing life quality to that group. (bvsalud.org)
  • The studies reported were summarized in terms of five categories: type of investigation, workers studied, measurement methods, findings about suspected risk factors, and findings about programs for reducing risk. (cdc.gov)
  • Different treatment methods is an example of an experimental factor. (lu.se)
  • 1991). Apparently, what is still missing is a research line on the effect of age on the processing of presuppositions (PSPs), namely the information implicitly communicated as taken for granted, which are another core level of pragmatic processing. (frontiersin.org)
  • Welcome to the 9th Aging Research and Drug Discovery (ARDD) Meeting. (fightaging.org)
  • Non-medical factors that influence health-related outcomes and operate at different levels are the subject of an active research community. (who.int)
  • Because it is of greater valuable to spend more time learning about DOE than actually running the experiment, here is where the macro was employed to generate the response data. (isixsigma.com)
  • Increasing aging time increased (P (usda.gov)
  • Increased aging time generally decreased (P (usda.gov)
  • When you have uploaded and imported your raw data, collected and registered all information and annotations about samples, hybridizations, and other items, it is time to collect everything in an experiment. (lu.se)
  • The experimental factors of an experiment are the variables you are studying in the experiment. (lu.se)
  • In the BASE world an experimental factor is the same as an annotation type. (lu.se)
  • Since you probably have lots of annotations on your items that are not relevant for the experiment you must select the annotations types that should make up the experimental factors of the experiment. (lu.se)
  • Use the Add annotation types button to select the annotation types that should be used as experimental factors. (lu.se)
  • Use the Item overview function to verify that all your raw bioassays has been annotated or inherited values for all experimental factors. (lu.se)
  • [1] Some researchers have defined book deserts by linking them to poverty and low income, while others use a combination of factors that include census data, income, ethnicity, geography, language, and the number of books in a home. (wikipedia.org)
  • The raw data type to use in the experiment. (lu.se)
  • Cells in a specific area of the brain thought to be important for inhibitory control appear biologically older in individuals with cocaine use disorder (CUD), suggesting that the cells may age faster when exposed to cocaine, researchers report. (medscape.com)
  • Comparison of relative response factors (ratio of native analyte to stable isotope labeled internal standard) with known standard concentrations yields individual analyte concentrations. (cdc.gov)
  • Studies show that exercise stimulates nerve cells to produce chemicals called neurotrophic factors that act like "fertilizer" for the brain. (sciencebuddies.org)
  • Moreover, experiments in animals suggest that traffic-related air pollution is a developmental neurotoxicant-a factor that disrupts brain development. (plos.org)
  • Can Cocaine Addiction Lead to Faster Brain Aging? (medscape.com)
  • We performed gain and loss of function studies for leukemia inhibitory factor (LIF) and showed a depletion of NSCs, a subset of multipotential neural precursors and immature oligodendrocytes in LIF null mice. (karger.com)
  • Our studies also show that these NPs have differential requirements for LIF and ciliary neurotrophic factor (CNTF) and for epidermal growth factor (EGF), fibroblast growth factor (FGF-2) and platelet-derived growth factor (PDGF) for their propagation in vitro. (karger.com)
  • In addition, sections of the exhibition cover subjects such as mind control, which became a prominent factor in the way Americans understood the Korean War. (peoplesworld.org)
  • The trainees' task is to choose which factors they think may affect the number of acquired customers and determine the corresponding factor levels that they want to test. (isixsigma.com)
  • Rolling thin-film oven test (RTFOT) and pressure aging vessel (PAV) test were utilized to simulate the short-term and long-term aging for asphalt binder. (hindawi.com)
  • Imagine an experiment designed to test the effect of physical activity on memory. (sciencebuddies.org)
  • Rejuvenation therapies aim to reverse or repair age-related cellular changes such as molecular waste, calcification , tissue stiffening , loss of stem cell function , genetic alterations, and impaired energy production . (fightaging.org)
  • Social sciences, for example, investigate the social determinants of health, which include the conditions in which people are born, grow, work, live and age, as well as the wider set of forces and systems shaping the conditions of daily life and health outcomes. (who.int)
  • From its vibrant colors and its irresistible viscosity to the delightful way it can be manipulated, squeezed and stretched, there's no doubt that slime is quite possibly one of the most popular science products for kids of all ages. (stevespanglerscience.com)
  • Check out our online library of hand-on experiments, many of which show you how to make slime art at home with common household products. (stevespanglerscience.com)
  • At Steve Spangler Science, we've made it our mission to get kids excited about science by upping the "wow" factor in each of our products. (stevespanglerscience.com)
  • Lean color is the primary factor in consumer purchase decisions and products with insufficient color life are discounted or discarded. (usda.gov)
  • To create a new experiment you can either mark one ore more raw biossays on the raw bioassays list view and use the New experiment button. (lu.se)
  • You can also create a new experiment from the experiments list view. (lu.se)
  • Added note, in response to immediate input from a reader of this post: Resveratrol is an anti-TNF (tumor necrosis factor) agent and in some instances this may trigger autoimmune symptoms . (dericbownds.net)
  • The factors responsible for response to tamoxifen in 5% to 10% of patients with ERa-negative tumors are not clear. (lu.se)
  • Long-term aging is found to reduce the adhesion fatigue lives for rubber asphalt and aggregate system, while the effect of long-term aging for aggregate and PG64-22 binder system is positive. (hindawi.com)
  • The present work takes a first step towards a psycholinguistic investigation on the potential impact of the aging factor on the processing of PSPs. (frontiersin.org)
  • Choice of factors, levels, and ranges. (isixsigma.com)
  • IQ scores, age equivalent scores and attention levels were attained for each participant. (abainternational.org)