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  • caapi vine
  • It has been noted that effects can be had from imbibing the Caapi vine alone, but that DMT-containing plants remain inactive when drunk as a brew without an MAO inhibitor (such as Caapi). (academic.ru)
  • contradictory] The caapi vine itself was the subject of a dispute between U.S. entrepreneur Loren Miller and the Coordinating Body of Indigenous Organizations of the Amazon Basin (COICA). (wikipedia.org)
  • It has been reported that some effects can be felt from consuming the caapi vine alone, but that DMT-containing plants (such as Psychotria ) remain inactive when drunk as a brew without a source of monoamine oxidase inhibitor (MAOI) such as B. caapi . (infogalactic.com)
  • brew
  • Ayahuasca which means 'the vine of the soul' is a powerfully psychoactive brew which is thought to have been used for several hundred years by indigenous people in the Amazon. (medindia.net)
  • The vine and the ayahuasca brew are legal ambiguities, since nowhere in the Controlled Drugs and Substances Act is it stated that natural material containing a scheduled substance is illegal, a position supported by the United Nations International Narcotics Control Board. (wikipedia.org)
  • MAOI
  • When these 2 plants are combined, however, the MAOI activity of the vine allows the DMT to cross into the brain, which in turn leads to the visionary effect that many users report experiencing. (ndnr.com)
  • Telepathine
  • It was assumed to be a newly discovered chemical at the time, however, it was soon realized that Telepathine was already more widely known as "harmine" from its previous discovery in Peganum harmala (Syrian Rue). (wikipedia.org)
  • enzyme
  • Individual polymorphisms in the cytochrome P450-2D6 enzyme affect the ability of individuals to metabolize harmine. (academic.ru)
  • The β-carbolines in the vine temporarily inhibit the production of this enzyme, allowing the DMT to reach the sensitive parts while still active. (ayahuasca-info.com)