Newer gamma cameras using simultaneous 180° acquisition appear to have the potential of offering similar benefits as PET technology but are able to use the less costly technetium (TC)-99m-based radiopharmaceuticals and thallium-201 (Tl-201). (medscape.com)
Attenuation is more likely with technetium-99m ( 99m Tc) than with radioactive thallium 201 (Tl-201). (msdmanuals.com)
Cardiac8
In patients with ischemic heart disease who undergo revascularization based on PET viability assessment with fludeoxyglucose F-18 (F-18 FDG), those with a low myocardial perfusion reserve were at an increased risk of adverse cardiac events. (medscape.com)
A MIBI scan or sestamibi scan is now a common method of cardiac imaging. (wikipedia.org)
Навантажувальна проба In stress testing, the heart is monitored by electrocardiography (ECG) and often imaging studies during an induced episode of increased cardiac demand so that ischemic areas potentially at risk. (msdmanuals.com)
The American Heart Association recommends that in nonemergency settings, patients should be informed of the risks (including those associated with radiation) and benefits involved in the use of cardiac CT scanning, radiopharmaceuticals, and fluoroscopy. (medscape.com)
Careful evaluation of the patient's history and physical examination (including signs of congestion, such as jugular venous distention) can provide important information about the underlying cardiac abnormality in heart failure (HF). (medscape.com)
HFpEF (heart failure with preserved ejection fraction) diagnosis requires evidence of cardiac structural or functional abnormalities as well as elevated plasma NP (natriuretic peptide) concentrations consistent with LV diastolic dysfunction and increased LV filling pressures. (medscape.com)
about one third of heart failure patients are also iron deficient, which is associated with poor cardiac function and can worsen outcomes in these individuals. (medscape.com)
Price S, Kaski JC, Al-Lamee R, Boden WE, Huber K, Katz JN, Krychtiuk K. The year in cardiovascular medicine 2022: the top 10 papers in acute cardiac care and ischaemic heart disease. (bu.edu)
Cardiomyopathy3
GTN can also be used alone or in combination with other agents to decrease the number of ischaemic episodes in patients with proven CAD or ischaemic cardiomyopathy with a high degree of effectiveness. (bmj.com)
Heller GV, Kapetanopoulos A. Use of Adenosine Technetium-99m Sestamibi Gated- SPECT to Differentiate Between Ischemic and Non-ischemic Dilated Cardiomyopathy in a Diabetic Woman. (cardioepemvasis.gr)
Liga R, Colli A, Taggart DP, Boden WE, De Caterina R. Myocardial Revascularization in Patients With Ischemic Cardiomyopathy: For Whom and How. (bu.edu)
Methoxyisobutylisonitrile2
The drug is a coordination complex consisting of the radioisotope technetium-99m bound to six (sesta=6) methoxyisobutylisonitrile (MIBI) ligands. (wikipedia.org)
Lack of technetium-99m methoxyisobutylisonitrile ((99m) Tc-MIBI) uptake is consistently reported to predict poor response to subsequent chemotherapy in a variety of human malignant tumours. (cnr.it)
Since (99m) Tc-MIBI accumulates within mitochondria, which also play a central role in apoptosis through the integration of death signals by Bcl-2 family members, we tested whether early (99m) Tc-MIBI uptake is affected by alterations of the apoptotic pathway. (cnr.it)
Forty-two breast cancer patients were intravenously injected with 740 MBq of (99m) Tc-MIBI and planar images were obtained 10 min post injection with the patients in the prone lateral position. (cnr.it)
Ten carcinomas failed to accumulate (99m) Tc-MIBI and could not be visualised on scintigraphic images despite being larger than 1. (cnr.it)
Thirty-two of the 42 breast carcinomas showed focal uptake of (99m) Tc-MIBI (MIBI positive), and 10 min tumour-to-background ratios (T/B) varied between 1. (cnr.it)
Heller GV, Kapetanopoulos A. Prognostic Value of Adenoscan Technetium-99m Sestamibi and Impact on Management of a Woman with Single-Vessel Coronary Artery Disease. (cardioepemvasis.gr)
Radioactive1
In general, nuclear medicine studies involve the use of a radioactive source, usually technetium ( 99m Tc), which has a short half life (six hours). (bmj.com)
Mitochondria1
Sestamibi is taken up by tissues with large numbers of mitochondria and negative plasma membrane potentials. (wikipedia.org)
Intravenously1
Technetium (99mTc) sestamibi is a lipophilic cation which, when injected intravenously into a patient, distributes in the myocardium proportionally to the myocardial blood flow. (wikipedia.org)
Acute2
Marked ischemic ST-segment elevations in inferior limb leads (II, III, aVF) and laterally (V 6 ) suggestive of acute inferolateral MI, and prominent ST-segment depressions with upright T waves in V 1 -V 4 are consistent with associated acute posterior MI. (basicmedicalkey.com)
My principal research interests include studies in stable ischemic heart disease, post-MI secondary prevention, acute coronary syndromes, and preventive cardiology. (bu.edu)
Patients3
For approximately one third of patients, CAD is not diagnosed until after a heart attack occurs. (medscape.com)
It is the test of choice for patients with active chest pain, an ECG with no ischemic changes, and an initial negative troponin result, according to the American College of Radiology guidelines. (medscape.com)
Two patients had past medical history of arteriosclerosis and coronary heart disease or cerebral infarction. (bvsalud.org)
Breast cancer1
More recently, breast radiologists administer lower doses of 99mTc sestamibi (approximately 150-300 MBq or 4-8 mCi) for Molecular Breast Imaging (MBI) scans which results in a high sensitivity (91%) and high specificity (93%) for breast cancer detection. (wikipedia.org)
Failure1
The CBC aids in the assessment of severe anemia, which may cause or aggravate heart failure. (medscape.com)
Areas1
The resulting two sets of images are compared with each other to distinguish ischemic from infarcted areas of the myocardium. (wikipedia.org)
Disease1
Frequently, the disease is diagnosed only after the patient has had a heart attack. (medscape.com)
Human1
For example, 99m Tc-methylene diposphonate (MDP) binds to bone while 99m Tc-iminodiacetic acid (IDA) is taken up and excreted by the hepatocytes, and labelled macroaggregates of human serum albumin ( 99m Tc-MAA) are trapped in the terminal pulmonary arterioles due to their relatively large size. (bmj.com)