Targets tyrosine kinases protein kinase inhibitors. Medical search. Frequent questions

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Anatomy15

Cells, Cultured Cell Line Cell Line, Tumor Tumor Cells, Cultured 3T3 Cells Fibroblasts Cell Nucleus Cell Membrane HeLa Cells Cytosol PC12 Cells Neurons CHO Cells Cell Line, Transformed Muscle, Smooth, Vascular

Organisms7

Rats, Sprague-Dawley Mice, Inbred C57BL Mice, Knockout Cattle Rats, Wistar Rabbits Cricetinae

Diseases2

Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cell Transformation, Neoplastic

Chemicals and Drugs171

Protein Kinase Inhibitors Phosphatidylinositol 3-Kinases Protein Kinase C Protein Kinases Proto-Oncogene Proteins c-akt Protein-Serine-Threonine Kinases Tyrosine Enzyme Inhibitors Protein-Tyrosine Kinases Proto-Oncogene Proteins Cyclic AMP-Dependent Protein Kinases Calcium-Calmodulin-Dependent Protein Kinases Mitogen-Activated Protein Kinases Chromones Staurosporine p38 Mitogen-Activated Protein Kinases Morpholines 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine src-Family Kinases Mitogen-Activated Protein Kinase 1 Extracellular Signal-Regulated MAP Kinases Receptor Protein-Tyrosine Kinases Mitogen-Activated Protein Kinase 3 Isoquinolines Mitogen-Activated Protein Kinase Kinases Alkaloids Genistein JNK Mitogen-Activated Protein Kinases Intracellular Signaling Peptides and Proteins Indole Alkaloids Phosphoproteins Piperazines Pyrimidines Isoenzymes Indoles Carbazoles Protein Kinase C-alpha Protein Kinase C-delta Phosphotyrosine Tetradecanoylphorbol Acetate RNA, Messenger Cyclic AMP Cyclic GMP-Dependent Protein Kinases Cyclin-Dependent Kinases Receptor, Epidermal Growth Factor Pyridines CDC2 Protein Kinase Benzamides Calcium Casein Kinase II Protein Tyrosine Phosphatases AMP-Activated Protein Kinases p21-Activated Kinases MAP Kinase Kinase 1 Serine Flavonoids MAP Kinase Kinase Kinases Recombinant Proteins Protein Kinase C-epsilon Carrier Proteins Protein Kinase C beta Casein Kinases Antineoplastic Agents Androstadienes Recombinant Fusion Proteins Ribosomal Protein S6 Kinases Tyrphostins Maleimides Proto-Oncogene Proteins c-abl Quinazolines Imidazoles eIF-2 Kinase rho-Associated Kinases Calcium-Calmodulin-Dependent Protein Kinase Type 2 Phosphotransferases (Alcohol Group Acceptor)Lymphocyte Specific Protein Tyrosine Kinase p56(lck)Cyclin-Dependent Kinase Inhibitor p27 MAP Kinase Kinase 4 Proto-Oncogene Proteins pp60(c-src)Membrane Proteins Focal Adhesion Kinase 1 Focal Adhesion Protein-Tyrosine Kinases Nitriles Focal Adhesion Kinase 2 Janus Kinase 2 Creatine Kinase Adenosine Triphosphate Pyrroles Tyrosine 3-Monooxygenase Isoflavones Cyclin-Dependent Kinase Inhibitor p21 Phosphoprotein Phosphatases Phorbol 12,13-Dibutyrate DNA-Binding Proteins Adaptor Proteins, Signal Transducing Okadaic Acid Glycogen Synthase Kinase 3 Phorbol Esters Proto-Oncogene Proteins c-fyn Proteins DNA Primers Pyruvate Kinase Sulfonamides Epidermal Growth Factor Aurora Kinases Diglycerides CDC2-CDC28 Kinases Cell Cycle Proteins Butadienes fms-Like Tyrosine Kinase 3 1-Phosphatidylinositol 4-Kinase Thymidine Kinase Type C Phospholipases I-kappa B Kinase Myosin-Light-Chain Kinase Vanadates Quinones Cyclic AMP-Dependent Protein Kinase Type II Transcription Factors Insulin Diacylglycerol Kinase Fusion Proteins, bcr-abl Threonine Thiazoles Ribosomal Protein S6 Kinases, 90-kDa RNA, Small Interfering Naphthalenes MAP Kinase Kinase 2 Phosphoserine 3-Phosphoinositide-Dependent Protein Kinases MAP Kinase Kinase Kinase 1 Lactams, Macrocyclic Proto-Oncogene Proteins c-kit Ethers, Cyclic Pyrazoles Benzoquinones Nuclear Proteins TOR Serine-Threonine Kinases Peptides NF-kappa B Benzophenanthridines Mitogen-Activated Protein Kinase 8 Phospholipase C gamma Mitogen-Activated Protein Kinase 14 Cyclins Phenanthridines Cyclic GMP Cyclin-Dependent Kinase 2 DNA-Activated Protein Kinase Proto-Oncogene Proteins c-met Receptor, Insulin DNA Actins Colforsin 8-Bromo Cyclic Adenosine Monophosphate Janus Kinase 1 Protamine Kinase DNA, Complementary Trans-Activators Calmodulin TYK2 Kinase MAP Kinase Kinase 6 Receptors, Platelet-Derived Growth Factor Thionucleotides Platelet-Derived Growth Factor Janus Kinase 3 GRB2 Adaptor Protein Tumor Necrosis Factor-alpha MAP Kinase Kinase 3 Protein Tyrosine Phosphatase, Non-Receptor Type 11 Receptors, Cell Surface

Analytical, Diagnostic and Therapeutic Techniques and Equipment13

Blotting, Western Transfection Immunoblotting Cloning, Molecular Precipitin Tests Models, Biological Reverse Transcriptase Polymerase Chain Reaction Mutagenesis, Site-Directed Immunohistochemistry Electrophoresis, Polyacrylamide Gel Models, Molecular Peptide Mapping Microscopy, Fluorescence

Phenomena and Processes43

Phosphorylation Signal Transduction Enzyme Activation MAP Kinase Signaling System Apoptosis Amino Acid Sequence Transfection Cell Survival Mutation Kinetics Protein Binding Base Sequence Dose-Response Relationship, Drug Cell Division Protein Structure, Tertiary Substrate Specificity Time Factors Binding Sites Cell Cycle Cell Proliferation Gene Expression Regulation Sequence Homology, Amino Acid Transcription, Genetic Gene Expression Down-Regulation src Homology Domains Up-Regulation Gene Expression Regulation, Enzymologic Cell Differentiation Cell Movement Molecular Weight Structure-Activity Relationship Drug Resistance, Neoplasm Cell Adhesion Protein Transport Protein Processing, Post-Translational Drug Synergism Biological Transport Promoter Regions, Genetic Enzyme Induction Second Messenger Systems Transcriptional Activation Mitosis

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Anatomy Organisms Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science

Protein Kinase Inhibitors Phosphatidylinositol 3-Kinases Protein Kinase C Protein Kinases Proto-Oncogene Proteins c-akt Phosphorylation Protein-Serine-Threonine Kinases Tyrosine Signal Transduction Enzyme Activation Enzyme Inhibitors Protein-Tyrosine Kinases Proto-Oncogene Proteins Cyclic AMP-Dependent Protein Kinases Calcium-Calmodulin-Dependent Protein Kinases MAP Kinase Signaling System Mitogen-Activated Protein Kinases Cells, Cultured Chromones Staurosporine Cell Line p38 Mitogen-Activated Protein Kinases Morpholines 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine src-Family Kinases Mitogen-Activated Protein Kinase 1 Extracellular Signal-Regulated MAP Kinases Receptor Protein-Tyrosine Kinases Blotting, Western Mitogen-Activated Protein Kinase 3 Molecular Sequence Data Apoptosis Isoquinolines Cell Line, Tumor Mitogen-Activated Protein Kinase Kinases Amino Acid Sequence Alkaloids Genistein JNK Mitogen-Activated Protein Kinases Intracellular Signaling Peptides and Proteins Indole Alkaloids Phosphoproteins Piperazines Pyrimidines Transfection Isoenzymes Cell Survival Indoles Mutation Carbazoles Kinetics Protein Binding Protein Kinase C-alpha Protein Kinase C-delta Phosphotyrosine Tetradecanoylphorbol Acetate Tumor Cells, Cultured RNA, Messenger Cyclic AMP Cyclic GMP-Dependent Protein Kinases Cyclin-Dependent Kinases Receptor, Epidermal Growth Factor Base Sequence Pyridines CDC2 Protein Kinase Dose-Response Relationship, Drug Benzamides Calcium Cell Division Casein Kinase II Protein Tyrosine Phosphatases AMP-Activated Protein Kinases p21-Activated Kinases MAP Kinase Kinase 1 Serine Flavonoids MAP Kinase Kinase Kinases Recombinant Proteins Immunoblotting Protein Kinase C-epsilon Protein Structure, Tertiary Carrier Proteins Protein Kinase C beta Substrate Specificity 3T3 Cells Casein Kinases Antineoplastic Agents Time Factors Androstadienes Binding Sites Recombinant Fusion Proteins Ribosomal Protein S6 Kinases Tyrphostins Cell Cycle Rats, Sprague-Dawley Maleimides Cell Proliferation Proto-Oncogene Proteins c-abl Quinazolines Imidazoles

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