T lymphocyte subsets. Medical search. Frequent questions

Levels of lymphocyte subsets were determined by flow cytometry. (providence.org)
Also, whole blood was recovered, and the number of circulating total leukocytes, as well as specific lymphocyte subsets, was determined by flow cytometry. (cdc.gov)

Clinical changes in disease expression measured by a disease activity score were correlated with changes in percentages of peripheral blood lymphocyte subsets. (northwestern.edu)
Eisenstein, DM, O'Gorman, MRG & Pachman, LM 1997, ' Correlations between change in disease activity and changes in peripheral blood lymphocyte subsets in patients with juvenile dermatomyositis ', Journal of Rheumatology , vol. 24, no. 9, pp. 1830-1832. (northwestern.edu)

Production of interferons and change of the lymphocyte subpopulation phenotype in peripheral blood at cervical papillomavirus infection. (wikigenes.org)
001). The peripheral CD8+ lymphocyte subpopulation includes four distinct cell subsets: TCRgammadeltaCD8alphaalpha T cells, CD3 --CD8alphaalpha lymphocytes (NK cells) and TCRalphabetaCD8alphabeta T cells, and TCRalphabetaCD4+CD8alphaalpha, and putatively TCRalphabetaCD4 --CD8alphaalpha T cells. (iastate.edu)
Our data demonstrate that ZAP-70 is expressed in a subpopulation of tonsillar and splenic normal B-lymphocytes that express an activated phenotype. (elsevierpure.com)

The heterogeneity of tumor infiltrating lymphocytes (TILs) is not well characterized in brain metastasis. (akoyabio.com)
Comparison of tumor biopsies before and after treatment reveals an increase of activated, conventional CD4+ tumor-infiltrating lymphocytes (TIL) in most patients and higher clonality by TCRβ sequencing. (bepress.com)
Researchers determined that the number of tumor-infiltrating lymphocytes (TILs) present in esophageal cancer tumors correlated with patient long-term survival rates. (sciencedaily.com)
A subset of these are called tumor-infiltrating lymphocytes (TILs). (sciencedaily.com)

Altered cellular immune function has been demonstrated in patients with lung cancer, including decreased numbers of circulating lymphocytes and changes in the percentage of lymphocytes in various functional subsets. (elsevierpure.com)

CD45 lymphocyte count was designated the total lymphocyte count. (cdc.gov)

Lymphocyte populations in cancer patients were compared to those of nonsmokers and a smoking patient population. (elsevierpure.com)
To investigate the effects of age and gender on human lymphocyte populations, we studied lymphocyte subsets and their expression of activation markers in peripheral blood in healthy people above the age of 21, and analyzed this according to gender. (biomedcentral.com)
Evidence from this study indicates that pulmonary exposure to certain welding fumes cause decrements in systemic immune cell populations, specifically circulating T-lymphocytes, and these alterations in immune cell number are not dependent exclusively on Mn, but likely a combination of other metals present in welding fume. (cdc.gov)

Breg cell, regulatory B cell T lymphocyte The percentage of CD4+ T cells at different stages of differentiation were calculated, and significant differences between the AS patients and HCs are shown in Fig.?2. (scienza-under-18.org)
B10 cell, IL-10 producing regulatory B cell The number of regulatory lymphocytes detected in the blood of the AS patients changed significantly after Anbainuo treatment, with the percentage of Treg FLJ20315 cells (CD3+CD4+CD25+CD127? (scienza-under-18.org)
The cause of the change in percentage of lymphocyte subsets with age, and the different effects on males and females is not fully understood but warrants further study. (biomedcentral.com)
Changes in the percentage of peripheral blood CD 19 positive lymphocytes (B cells) correlated with changes in disease activity (Spearman rank coefficients = 0.47, p = 0.02). (northwestern.edu)
With CD45 gating, the relative numbers of beads and lymphocyte subsets are enumerated, and their absolute numbers and percentage values are calculated. (cdc.gov)
Single-platform technology (SPT) is designed to enable de- system and managing the health care of persons infected with terminations of both absolute and percentage lymphocyte sub- human immunodeficiency virus (HIV) ( 1-4 ). (cdc.gov)

SH2D1A was positively correlated with immunoglobulin A , immunoglobulin G and TL subsets (CD3+, CD4+ and CD8+) (P (bvsalud.org)

Enumeration of CD4+ lymphocytes in HIV-positive participants and age-matched controls was performed on cryopreserved whole blood using the method reported by Fiebig et. (cdc.gov)
De Paoli P, Reitano M, Battistin S, Castiglia C, Santini G. Enumeration of human lymphocyte subsets by monoclonal antibodies and flow cytometry: a comparative study using whole blood or mononuclear cells separated by density gradient centrifugation. (bdbiosciences.com)

We hypothesized that CLA modifies peripheral lymphocyte phenotype, regardless of the environment. (iastate.edu)
Owing to the prognostic value of B-CLL ZAP-70 expression, this phenotype may reflect intrinsic biological differences between the two subsets of disease. (elsevierpure.com)

The expression of three of these genes was further tested by quantitative RT-PCR in lymphocyte subpopulations [CD4+ and CD8+ T, CD19+ B, CD56+ natural killer cells and peripheral blood lymphocytes (PBLs)] from ten adult donors. (sckcen.be)
The level of BAX activation in the various subpopulations correlated with the sensitivity of the cells to radiation, suggesting its possible role in the differential radiosensitivity of hematopoietic cell subsets. (sckcen.be)
In this study we have established culture conditions that allow the preferential and rapid expansion of either T cell receptor (TCR) + /CD3 + 16 - T lymphocytes or TCR - /CD3 - 16 - natural killer (NK) cells, or the non-selective outgrowth of both subsets. (wustl.edu)
In seven patients (44%), the abnormal ratio resulted from an increase in the absolute number of suppressor cells with a normal number of helper T lymphocytes. (elsevierpure.com)
We quantitated the subsets of immune-cells utilizing a targeted panel of proteins including PanCK, CD8, CD4, VISTA and IBA-1, and analyzed an average of 15,000 cells per sample. (akoyabio.com)
However, we have identified a distinct subset of human NK cells that are deficient for FcRγ expression but express normal levels of CD3ζ. (nih.gov)
Thus, our study reveals FcRγ-deficient NK cells as a novel subset of human NK cells that have remarkably potent responses toward antibody-coated targets. (nih.gov)
Various subsets of invariant natural killer T (iNKT) cells with different cytokine productions develop in the mouse thymus, but the factors driving their differentiation remain unclear. (nih.gov)
Furthermore, MP increased WBC and HGB counts and reduced the ratio of G0/G1 phase obviously, increased the proportion of S phase and G2/M phase in peripheral blood lymphocytes, increased the counts of CD4+ T cells and the ratio of CD4+/CD8+, and reduced the inhibition rate of splenic lymphocytes. (hindawi.com)
Recent studies using neutralizing anti-CCL5 antibodies have suggested that the constitutive expression of CCL5 plays a regulatory role in maintaining tissue-resident memory (Trm) T cells in the human vaginal tract 9 and mouse skin 10 , suggesting that constitutive CCL5 expression in noninflamed conditions, hereafter referred to as homeostatic CCL5 expression, might be important for homeostasis of tissue-resident lymphocytes. (nature.com)
However, it remains unclear whether CLL-B cells aberrantly acquire ZAP-70 expression during the transformation process or whether ZAP-70 may be expressed under certain conditions in normal human B-lymphocytes. (elsevierpure.com)
CD27, a lymphocyte-specific member of the TNF/NGF-R family, is expressed on the majority of peripheral blood T cells. (aai.org)
There is evidence that also in vivo, CD4+ cells that have persistently been stimulated by Ag, accumulate within the CD45RA-CD27- subset. (aai.org)
In agreement with earlier findings, all CD4+CD45RA+CD45RO- T cells were found to express CD27, whereas a small fraction of the CD4+CD45RA-CD45RO+ subset lacks the molecule. (aai.org)
CD4+ T-cells and other lymphocyte subsets in persons infected with human immunodeficiency virus (HIV). (cdc.gov)
HIV infection is characterized by a decrease and, eventually, a depletion of CD4+ T-lymphocytes (helper T cells). (cdc.gov)
Using immunophenotyping, HIV-positive blood samples and age-matched controls were tested for the proportion of lymphocytes that are T cells, B cells, natural killer (NK) cells, CD4+ T cells (helper T cells), and CD8+ T cells (suppressor/inducer T cells). (cdc.gov)
Mycobacterium bovis, the causative agent of bovine tuberculosis is known to persist within granulomas, distinct lesions represented by a caseonecrotic core surrounded by epithelioid macrophages, T-lymphocytes, B-lymphocytes, Langhans-type multinucleated giant cells and fibroblasts. (usda.gov)
and (iii) the dramatic reductions to lymphocyte numbers and function 1-2 h after exercise reflects a transient and time-dependent redistribution of immune cells to peripheral tissues, resulting in a heightened state of immune surveillance and immune regulation, as opposed to immune suppression. (frontiersin.org)
about 75% of the lymphocytes are T cells, 20% B cells, and 5% NK cells. (msdmanuals.com)

Thus, this study investigated the effects of masturbation-induced orgasm on lymphocyte circulation and cytokine production in healthy young males. (karger.com)
Limitations: Although elevations of lymphocyte subsets in major depressive and OCD patients were observed, conclusions concerning immune status in OCD ought to be held in abeyance pending assessment of other indices of immune and cytokine functioning. (aku.edu)

Monocyte subsets display age-dependent alterations at fasting and undergo non-age-dependent changes following consumption of a meal. (usda.gov)

In addition, leukocyte and lymphocyte subsets were analyzed via flow cytometry, and the production of lipopolysaccharide-induced interleukin 6 and tumor necrosis factor alpha was measured before and then 5 and 45 min after the orgasm. (karger.com)
The elements were evaluated by the total number of peripheral leukocyte, granulocyte and lymphocyte ratio and lymphocyte subsets. (scirp.org)
The number of leukocyte subsets, granulocyte and lymphocyte were also regulated by dose dependent manner. (scirp.org)

Optimal proliferation of lymphocytes was obtained using a combination of irradiated allogeneic peripheral blood lymphocytes (PBL) and irradiated Epstein Barr virus (EBV) transformed lymphoblastoid B cell lines (B-LCL). (wustl.edu)

Cumulative physiological stress is associated with age-related changes to peripheral T lymphocyte subsets in healthy humans. (usda.gov)

During the initial phase of the disease, patients demonstrated an increase in the total lymphocyte counts (CD3). (tubitak.gov.tr)
The guidelines describe single-platform technology (SPT), a process in which absolute counts of lymphocyte subsets are measured from a single tube by a single instrument. (cdc.gov)
T-lymphocyte counts, with special emphasis and stunted children has not changed dra- on the effect of nutritional rehabilitation. (who.int)

Serum from145 iGCTs patients were collected and lymphocyte subsets were analyzed by flow cytometry. (researchsquare.com)
Lymphocyte subset analysis by flow cytometry. (bdbiosciences.com)
Clinical Applications of Flow Cytometry: Quality Assurance and Immunophenotyping of Lymphocytes: Approved Guideline. (bdbiosciences.com)
Lymphocyte immunophenotyping by flow cytometry in normal adults: comparison of fresh whole blood lysis technique, Ficoll-Paque separation and cryopreservation. (bdbiosciences.com)

Human lymphocyte subpopulations differ in their cellular responses to ionizing radiation. (sckcen.be)
In contrast to DDB2, TNFRSF10B and BAX were differentially modulated among the subpopulations and the PBLs, being more activated in irradiated CD19+ B and CD8+ T lymphocytes. (sckcen.be)
In contrast, within the CD8+ compartment CD27- subsets were found both in the CD45RA+ and CD45RA- subpopulations. (aai.org)
If the complete blood count reveals lymphocytopenia, testing for immunodeficiency and analysis of lymphocyte subpopulations should follow, usually after the patient has recovered from any acute event. (msdmanuals.com)

This study retrospectively analyzed serum lymphocyte subsets and survival outcomes in intracranial germ cell tumors (iGCTs) patients. (researchsquare.com)

The levels of SH2D1A, signaling lymphocyte activation molecule (SLAM) and SLAM-associated protein (SAP) were significantly higher in the IM group than those in the control and CAEBV groups (P (bvsalud.org)
Identification of a molecule uniquely expressed on a gamma/delta TCR+ subset within bovine intestinal intraepithelial lymphocytes. (ox.ac.uk)

Because lymphocytes account for only 20 to 40% of the total white blood cell (WBC) count, lymphocytopenia may go unnoticed if the WBC count is checked without a differential. (msdmanuals.com)

polymorphonuclear leukocytes, and neutrophil ratios increased and eosinophil, mononuclear leukocytes, lymphocyte, and monocyte ratios were decrease when these values were compared to changes between days. (yyu.edu.tr)

It is common to evaluate lymphocytes subsets in virus infection, immunodeficiency diseases and cancer. (researchsquare.com)
Human Immunodeficiency Virus (HIV) Infection Human immunodeficiency virus (HIV) infection results from 1 of 2 similar retroviruses (HIV-1 and HIV-2) that destroy CD4+ lymphocytes and impair cell-mediated immunity, increasing risk of certain. (msdmanuals.com)

Effect of Graves' disease intrathyroidal lymphocytes (ITL) on xenotransplants of human thyroid tissue in athymic nude mice. (wikigenes.org)
Islet-infiltrating lymphocytes of individual male and female non-obese diabetic (NOD) mice were examined with the purpose of determining the differences that lead to a predominance of diabetes in female versus males NOD mice. (arizona.edu)
When normalized for the amount of islet lymphocytes recovered, the infiltrating lymphocytes of female NOD mice were indistinguishable from those of male NOD mice. (arizona.edu)

STUDY DESIGN AND METHODS: The hematopoietic progenitor cell (HPC) and lymphocyte subset (LS) content of approximately 8000 CB units were characterized, and these results were correlated with donor ethnicity, birth weight, gestational age, sex, and type of delivery. (emmes.com)

Lesions at all time-points contained large numbers of CD4+ T-lymphocytes with lesser numbers of CD8+ T-lymphocytes and few gamma/delta T-lymphocytes. (usda.gov)

Distinguishing between human lymphocyte subsets. (wikipedia.org)
To discriminate between these two possibilities, we assessed ZAP-70 expression in normal human B-lymphocytes. (elsevierpure.com)

A low ratio of CD4+ (helper) any chromosomal or hereditary disorder lymphocytes relative to CD8+ (suppressor) that caused the malnutrition. (who.int)

We quantitated lymphocyte subsets in 54 patients with lung cancer including patients with limited (stages 1 and 2) nonsmall cell lung cancer (NSCLC, n = 23), advanced (stage 3) NSCLC (n = 16), and small cell cancer (SCLC, n = 15). (elsevierpure.com)
Serum albumin was decreased in 15 lung cancer patients, and lymphocyte subsets were separately evaluated in these patients. (elsevierpure.com)
A decrease in population of T-lymphocytes subsets is frequent in patients with SCLC, advanced NSCLC, and lung cancer patients with hypoalbuminemia. (elsevierpure.com)
Method: Circulating lymphocytes were determined from morning blood samples taken from OCD and major depressive patients, as well as from age- and sex-matched controls. (aku.edu)
Finally, in a subset of patients, symptoms of the illness, stress/coping, and circulating lymphocytes, were also evaluated following 12 weeks of antidepressant medication (serotonergic reuptake inhibitor). (aku.edu)

To investigate whether changes in peripheral blood lymphocytes correlate with changes in disease activity in juvenile dermatomyositis (JDM). (northwestern.edu)
It is important to note that the lymphocytes in the blood represent only a small proportion of the total lymphocyte pool, and the lymphocyte count may not always correlate with the composition and numbers of lymphocytes in other lymphoid (eg, nodes, spleen) and non-lymphoid (eg, lung, liver) tissues. (msdmanuals.com)

Kidd P, Vogt R. Report of the workshop on the evaluation of T-cell subsets during HIV infection and AIDS. (bdbiosciences.com)
In acute viremia due to HIV or other viruses, lymphocytes may undergo accelerated destruction from active infection with the virus, may be trapped in the spleen or lymph nodes, or may migrate to the respiratory tract. (msdmanuals.com)

All enrolled thymic lymphocytes is widely accepted as infants were breastfed in addition to receiv- an indicator of the depression of thymus- ing some traditional foods, according to dependent immune competence associated their age. (who.int)
Lymphocytopenia may also reflect impaired lymphocyte production arising from destruction of thymic or lymphoid architecture. (msdmanuals.com)

Circulating activated lymphocyte subsets as potential blood biomarkers of cancer progression. (providence.org)
The objective of this study was to predict the value of lymphocyte subsets in cancer progression. (providence.org)

CLA synergized with a Brachyspira hyodysenteriae bacterin vaccine to expand the TCRgammadeltaCD8alphaalpha and NK cell subsets. (iastate.edu)
To address this, we performed a targeted analysis of immune-cell subsets in brain metastasis tissues to test immunosuppressive routes involved in brain metastasis. (akoyabio.com)
There were no significant correlations in disease activity with changes of T cell subsets or the T cell activation markers CD25 or DR. Conclusion. (northwestern.edu)
The mechanism was perhaps related to inhibiting lymphocyte apoptosis and promoting the balance of Th1/Th2 cell subsets. (hindawi.com)
This study was undertaken to analyze the regulation of CD27 on different T-cell subsets and to determine whether the loss of CD27 expression is an irreversible event and may thereby mark T-cell differentiation. (aai.org)
The Cambridge Biotech HIV-1 Western Blot Kit is manufactured by Calypte Corporation from HIV-I propagated in an H9/HTLV-IIIb T-lymphocyte cell line. (cdc.gov)
Influence of racial background on the distribution of T-cell subsets and Leu 11-positive lymphocytes in healthy blood donors. (bdbiosciences.com)
Analysis of T cell subsets in normal adults. (bdbiosciences.com)

McNerlan, SE, Alexander, HD & Rea, IM 1999, ' Age-related reference intervals for lymphocyte subsets in whole blood of healthy individuals ', Scandinavian Journal of Clinical and Laboratory Investigation , vol. 59, no. 2, pp. 89-92. (ulster.ac.uk)
Circulating activated lymphocyte subsets as potential blood biomarkers" by Ying-Yi Wang, Na Zhou et al. (providence.org)
The secondary objective was to assess the effect of anti-OX40 on lymphocyte subsets in the tumor and blood. (bepress.com)
The welding fume with the lower concentration of Mn had no significant effect on the numbers of blood lymphocytes and lymphocyte subsets compared to control values. (cdc.gov)
The level of The infants with PEM were enrolled in T-lymphocyte subsets in peripheral blood the study after fulfilling a set of inclusion provide information about the development criteria. (who.int)

To understand the correlation between changes in disease status (including CRP, BASDAI, and ASDAS) and changes in lymphocyte frequency after Anbainuo therapy, Spearmans rank correlation analyses showed that the decrease in CRP was positively correlated with the increase in the frequency of Tregs (CD3+CD4+CD25+CD127? (scienza-under-18.org)

Dynamic monitoring of serum lymphocyte subsets can be used as an auxiliary indicator for prognosis judgment. (researchsquare.com)

To more fully phenotypically characterize the lymphocyte subsets that are most influenced by dietary CLA supplementation and to elucidate the functional implications of their expansion, we conducted the second experiment. (iastate.edu)

Regulation of CD27 expression on subsets of mature T-lymphocytes. (aai.org)

Anatomy50

Organisms17

Diseases23

Chemicals and Drugs89

Analytical, Diagnostic and Therapeutic Techniques and Equipment36

Phenomena and Processes45

Disciplines and Occupations1

Information Science3

Health Care2

Determined by flow cytometry2

Peripheral blood lymphocyte subsets2

Subpopulation3

Tumor Infiltrating Lymphocytes4

Numbers of circulating1

Total lymphocyte count1

Populations3

Percentage6

Immunoglobulin1

Enumeration2

Phenotype2

Cells20

Cytokine2

Alterations1

Leukocyte3

Proliferation1

Humans1

Counts3

Flow4

Subpopulations4

Survival1

Molecule2

Differential1

Monocyte1

Immunodeficiency2

Mice3

Hematopoietic1

Gamma-delta1

Human2

Suppressor1

Patients5

Correlate2

Infection2

Thymic2

Progression2

Cell8

Blood5

CD251

Serum1

Functional1

Regulation1