• indole
  • Improved procedure for the preparation of 7-methoxy-2-methyl-1-(2-morpholinoethyl)-1H-indole-3-carboxylic acid, key intermediate in the synthesis of novel 3-amidoindole and indolopyridone cannabinoid ligands. (wikipedia.org)
  • intermediate
  • 6-chloro-2-fluoro-3-pyridineacetamide is used as an intermediate in most syntheses, which is then reacted through these three general steps to produce phantasmidine. (wikipedia.org)
  • yield
  • At least one substituent is required on the piperazine ring to achieve the cyclization in good yield. (dtu.dk)
  • step
  • The final step involves reacting this product with BH3 in THF, then reacting the product with piperazine in MeOH at reflux. (wikipedia.org)