• Activity
  • H. S. Patel, H. D. Desai, and H. J. Mistry, "Synthesis and Antimicrobial Activity of Some New Piperazine Derivaties Containing Aryl Sulfonyloxy Group," E-Journal of Chemistry , vol. 1, no. 2, pp. 93-98, 2004. (hindawi.com)
  • intermediate
  • 6-chloro-2-fluoro-3-pyridineacetamide is used as an intermediate in most syntheses, which is then reacted through these three general steps to produce phantasmidine. (wikipedia.org)
  • class
  • The expanding class of SLAP reagents provides access to piperazines from aromatic, heteroaromatic, and aliphatic aldehydes and ketones by using an iridium photoredox catalyst ( 747769 ) under exposure to blue light - without additional reagents or the generation of toxic byproducts. (sigmaaldrich.com)
  • step
  • The final step involves reacting this product with BH3 in THF, then reacting the product with piperazine in MeOH at reflux. (wikipedia.org)