Design, Targeted Synthesis and Study of Biological Activity of Some Polifunctional Chiral Terpenic Compounds. (ichem.md)
Our goal is to continue the synthesis of additional analogs to improve the potency Procyanidin B2 and biopharmaceutical properties of this class of compounds. (bio-biz-navi.com)
Derivatives4
Synthesis of pyridine derivatives 2a-l was accomplished by reductive animation of pyridine-2 6 (1) in the presence of an amine in Procyanidin B2 methanol with zinc chloride like a catalyst Procyanidin B2 and sodium cyanoborohydride as the reducing agent (Plan 1). (bio-biz-navi.com)
On the other hand, 6-aminouracils undergo nitrosation followed by reduction afforded 5,6-diaminouracil derivatives which used as a direct starting material for the synthesis of indenopteridines and indolopteridines via the reaction with ninhydrin and isatin respectively. (rroij.com)
In continuation to our interest in the chemical and biological activities of fused uracil derivatives, we report herein the synthesis of a new series of fused uracils starting from 6-aminouracil derivative [ 23 ] which have been converted into the nitrosoanalog by nitrosation. (rroij.com)
The synthesis of dihydroxyindenopyrrolopyrimidine derivatives 4-6 based on the addition reaction occurred in the reaction of ninhydrin and 6-aminouracils 1 in the presence of acetic acid. (rroij.com)
Pyridine1
General Procyanidin B2 procedure for the synthesis of pyridine analogs 2a-l To a solution of pyridine-2 6 (50 mg 0.37 mmol) in methanol (4 mL) was added an aniline (0.81. (bio-biz-navi.com)
Nitrogen1
The syntheses were carried out under nitrogen in dry glassware. (bio-biz-navi.com)
Reaction1
A simple one-pot synthesis of indenopyrrolopyrimidines and indolopyrrolopyrimidines through the cyclocondensation reaction of 6-aminouracils and ninhydrin and/or isatin in the presence of catalytic amounts of glacial acetic acid were described. (rroij.com)
Activity1
GRINCO, M. Occurrence, Biological Activity and Synthesis of Diterpenoid Amides. (ichem.md)