Surgery frozen sections. Medical search. Frequent questions

Intraoperative frozen section (FS) examination of the Sentinel node (SN) in breast cancer patients is questioned due to the relatively high number of positive SN(s) found in the permanent histological examination. (nih.gov)
Therefore, preoperative examination is important, and its exact diagnosis depends on the intraoperative frozen section and pathological examination. (spandidos-publications.com)
63cm small intestine with mesentery and the mass was resected merely in toto , and primary ileal mesenchymal tumor with whole intestinal layer invasion was suggested by the intraoperative frozen section. (researchsquare.com)
The detection of tumor cells during the intraoperative frozen section examination (IE) of sub-areolar/nipple tissue (SAT) leads to the removal of NAC, but frequently the final histology of the nipple is negative for malignancy. (unito.it)
Intraoperative frozen section (FS) diagnostics is an important diagnostic tool in neurosurgery, but agreement with final histopathology diagnoses may vary. (surgicalneurologyint.com)
8 ] Intraoperative frozen section (FS) of suspected intracranial tumors still remains an important diagnostic tool for the neurosurgeon to confirm that the targeted lesion is tumor tissue and to decide on the most appropriate surgical strategy. (surgicalneurologyint.com)

At the time of surgical biopsy, frozen section histology raised the possibility of a high-grade astrocytoma or lymphoma, prompting resection of a 3x3-cm well-circumscribed left frontal lobe mass. (cdc.gov)
The concept of sentinel node biopsy and utilization of the Maruyama Computer Program are significant components of stage-adapted gastric cancer surgery. (frontiersin.org)
Frozen section may be considered if the Surgeon is proceeding directly to further definitive surgery after excisional biopsy. (bccancer.bc.ca)
METHODS Synovial tissue specimens from 40 patients with RA and eight patients with non-rheumatic disease were obtained by arthroscopy guided biopsy techniques or during joint surgery. (bmj.com)
FNA biopsy is described as the most preferred test that has improved selection of patients for thyroid surgery (4).This study aims to review the existing protocol for the management of solitary thyroid nodules in our country and to assess the accuracy of the available diagnostic modalities in appropriate selection of patients. (priory.com)
He has a particular interest in cancer imaging, MRI-Ultrasound fusion targeted prostate biopsy, prostate cancer focal therapy, and robotic surgery for prostate and kidney cancer. (stanford.edu)
More accurate prostate biopsy enables better decision making about treatment options such as deciding between active surveillance and surgery. (stanford.edu)
But biopsy before surgery can lead to spillage of cancer. (cancerclinix.com)

If the tumor has metastasized, surgery is usually not curative, and the surgeon will choose a more conservative surgery, or no resection at all. (wikipedia.org)
A nodular lesion was found at the serosa of the sigmoid colon during the surgery, and a partial sigmoid colon resection was performed. (hindawi.com)
The patient underwent surgery and local resection of ampullary neoplasm was performed. (ispub.com)
Since Halsted (2) described the first local resection of ampullary lesions in 1899, the authors still debate on adequate surgery in this disease. (ispub.com)
More than a quarter of the ovary was removed by wedge resection and was sent for frozen sectioning. (who.int)
3 ] Surgery options are resection with wide margins or Mohs micrographic surgery (MMS) for a limited area of body regions' excision. (thieme-connect.de)
More than a quarter of the ovary which made the diagnosis and thus the was removed by wedge resection and was management straightforward with wedge sent for frozen sectioning. (who.int)
Ovarian oedema resection, frozen section and fixation of the was confirmed. (who.int)

But margin controlled surgery (CCPDMA) can be performed using a variety of tissue cutting and mounting methods, including Mohs surgery. (wikipedia.org)
In the performance of Mohs surgery, it is a simple method for real-time margin control of a surgical specimen. (wikipedia.org)
For invasive cSCC, surgical excision and Mohs micrographic surgery are the primary treatment options. (medscape.com)
The primary treatment for DFSP is surgical excision, which is wide local excision (WLE) with tumor-free margins, Mohs micrographic surgery (MMS), and partial or total amputation. (thieme-connect.de)

The microtome device that cold cuts thin blocks of frozen tissue is called a cryotome. (wikipedia.org)
The quality of the slides produced by frozen section is of lower quality than formalin fixed paraffin embedded tissue processing. (wikipedia.org)
this compound is known by many names and when frozen has the same density as frozen tissue. (wikipedia.org)
The principal use of the frozen section procedure is the examination of tissue while surgery is taking place. (wikipedia.org)
First-of-its-kind research shows promise for developing a method of clearly identifying cancerous tissue during surgery on one of the most common and deadliest types of brain tumor. (sciencedaily.com)
When expanded upon by further research, the findings offer the potential of improved outcome for those undergoing surgery to remove glioblastoma multiforme (GBM), a tumor that attacks tissue around nerve cells in the brain. (sciencedaily.com)
Using 40 frozen sections of GBM-riddled brain tissue, the Henry Ford team aimed to develop a database of normal brain matter, GBM and necrotic tissue as identified by Raman spectroscopy, as well as a statistical analysis algorithm for providing rapid diagnosis of tumor margins during brain surgery. (sciencedaily.com)
One complication of the study, which Kalkanis says was not unexpected, arose from the use of frozen tissue slices. (sciencedaily.com)
Artifacts of tissue damaged by freezing were found in many of the test samples and slightly lowered the accuracy of the team's analysis of some samples. (sciencedaily.com)
Frozen artifact can make it more difficult to visually identify normal brain matter and cancerous tissue, and also changes the basic molecular structure of the tissue. (sciencedaily.com)
But because we are developing these techniques to be used on live tissue during surgery, freeze artifact should not be a significant confounding factor," Kalkanis said. (sciencedaily.com)
Future studies, he said, will focus on methods of collecting and identifying Raman "signatures" from tissue with freeze artifact. (sciencedaily.com)
It can be performed on fresh tissue, frozen tissue, core biopsies scrapings obtained from the surface of small lesions or frozen sections, and on aspirates with reliable results. (bccancer.bc.ca)
Optimal tissue embedding is essential for smooth sectioning and ribboning. (leicabiosystems.com)
They were treated with TSS after frozen section analysis of the peritumoral testicular tissue. (canjurol.com)
this experimental method of fertility preservation involves surgery so as to remove, preserve and re-implant ovarian tissue. (sharedjourney.com)
Tissue sections on slides were analyzed for the presence of calcium salts using von Kossa staining. (cdc.gov)

The intraoperative consultation is the name given to the whole intervention by the pathologist, which includes not only frozen section but also gross evaluation of the specimen, examination of cytology preparations taken on the specimen (e.g. touch imprints), and aliquoting of the specimen for special studies (e.g. molecular pathology techniques, flow cytometry). (wikipedia.org)
Frozen section examination (FSE) revealed free tumor margins and absence of carcinoma. (ispub.com)
After surgery, the histopathological examination of the mass of the ampulla of Vater demonstrated an intraductal papillary mucinous neoplasm (Figure 2). (ispub.com)
Therefore, the patient refused conventional adjuvant therapy after the surgery and underwent regular physical examination follow-up. (spandidos-publications.com)

Vermooten V (1950) Indications for conservative surgery in certain renal tumors: a study based on the growth pattern of the cell carcinoma. (medscape.org)
We present our experience in performing testis sparing surgery (TSS) to treat sequential bilateral testicular tumors. (canjurol.com)
Tofte K, Berger C, Torp SH, Solheim O. The diagnostic properties of frozen sections in suspected intracranial tumors: A study of 578 consecutive cases. (surgicalneurologyint.com)
Surgery is the primary treatment of malignant tumors of the salivary glands. (medscape.com)

This inclination leads surgeons to minimal invasive surgery techniques. (ispub.com)
After personal research, I have discovered that Dr. Vipul Patel seems to be the go-to surgeon for the robotic surgery with Da Vinci, which is supposed to be minimally invasive and nerve-sparring which sounds exactly like what I need. (cancer.org)
I would not call this surgery minimally invasive. (cancer.org)
Unlike heart disease, diabetes or cancer, sepsis is usually the result of something else, like a cut or scrape, surgeries or invasive devices. (cdc.gov)

If the percentage of breast volume excised is estimated to exceed 20%, other techniques, such as oncoplastic breast surgery, with or without contralateral surgery, or mastectomy with reconstruction, may be considered. (springer.com)
Breast-conserving surgery (BCS), i.e. a partial mastectomy, followed by radiotherapy, is today a common alternative to mastectomy, when treating early breast cancer. (springer.com)
Importance: Patients with early breast cancer must choose between undergoing breast conservation surgery or mastectomy. (bvsalud.org)
Conclusions and Relevance: The results of this study demonstrated lower decisional conflict as measured by DCS score following use of the online, self-administered Navya-PPT among patients with early breast cancer choosing between breast-conserving surgery vs mastectomy. (bvsalud.org)

We included all cases were both an intraoperative FS and a formalin-fixed paraffin-embedded (FFPE) section had been acquired. (surgicalneurologyint.com)

This talk was presented at the 2018 SAGES Meeting/16th World Congress of Endoscopic Surgery by Antonio Cury during the IFSES Member Societies Update Symosium: Presentation of Each Society's Expertise - A World Congress extravaganza! (sages.org)

We evaluated the concordance between histopathologic features of frozen and paraffin-embedded SAT sections. (unito.it)
Soft tissues were dissected out and frozen sectioned en bloc into 15 micrometer longitudinal sections, while bones were paraffin embedded and cut into 5 micrometer sections, before mounting on coated slides. (cdc.gov)

Endoscopy& Endoscopic Surgery 7. (researchgate.net)

Pancreatic Surgery 3. (researchgate.net)

Although parathyroid surgery can be rewarding for the otolaryngologist or head and neck surgeon, it also can be vexing. (medscape.com)

She was discharged in a stable condition with laboratory/ radiological investigations and follow-up at neurosurgery, endocrine, radiotherapy, and thyroid surgery clinics. (surgicalneurologyint.com)
Time between date of surgery and first final diagnosis based on FFPE section, whether the patients had undergone previous brain surgery and/or prior cerebral radiotherapy were also registered. (surgicalneurologyint.com)
The Navya Patient Preference Tool (Navya-PPT) was developed as a survey-based presentation of evidence in an adaptive, conjoint analysis-based module for and trade-offs between cosmesis, adverse effects of radiotherapy, and cost of mandatory radiation following breast-conserving surgery. (bvsalud.org)

Given the limited evidence supporting these endorsements, we examined outcomes for 152 patients who underwent surgery for well-differentiated thyroid carcinoma at Memorial Sloan Kettering Cancer Center (MSK) from 1986 to 2015. (mskcc.org)
The records of all consecutive patients presenting with solitary thyroid nodules who underwent surgery from 1992 to 1997 in Imam Khomeini hospital were reviewed. (priory.com)

An intraoperative diagnosis with frozen section was not performed. (hindawi.com)
The diagnosis must be confirmed with surgery to inspect the abdominal cavity, take biopsies, and look for cancer cells in the abdominal fluid. (cancerclinix.com)

We present the case of a 30-year-old woman with findings of massive ovarian oedema on ultrasound imaging, and a discussion and literature review aiming to clarify that this is a benign tumour-like condition which every gynaecologist can encounter and that the most appropriate treatment is conservative surgery. (who.int)

2005) Assessment of surgical margins in renal cell carcinoma after nephron sparing: a comparative study: laparoscopy vs open surgery. (medscape.org)
Surgical margins assessment reduces re-excision rates in breast-conserving surgery I read with interest the article by Woon et al. (annals.edu.sg)

At four years after surgery, no local recurrence or metastasis has been found clinically. (hindawi.com)

The frozen section procedure is a pathological laboratory procedure to perform rapid microscopic analysis of a specimen. (wikipedia.org)
Furthermore, the assessment of the pathological state of SLNs during surgery is both time-consuming and expensive ( 6 , 7 ). (jcancer.org)

The frozen section procedure as practiced today in medical laboratories is based on the description by Dr Louis B. Wilson in 1905. (wikipedia.org)
Wilson developed the technique from earlier reports at the request of Dr William Mayo, surgeon and one of the founders of the Mayo Clinic Earlier reports by Dr Thomas S. Cullen at Johns Hopkins Hospital in Baltimore also involved frozen section, but only after formalin fixation, and pathologist Dr William Welch, also at Hopkins, experimented with Cullen's procedure but without clinical consequences. (wikipedia.org)
TSS after frozen section analysis appears to be a safe and feasible procedure that, in carefully selected cases, offers adequate cancer control, preserves sexual function, and provides psychological benefits. (canjurol.com)
During the procedure, the doctor removes the uterus via C-section and makes a small incision to operate on the baby. (emofree.com)
Dr. Bruner was reported as saying that when his finger was grasped, it was the most emotional moment of his life, and that for an instant during the procedure he was just frozen, totally immobile. (emofree.com)

1994) Expanding indications for conservative renal surgery in renal cell carcinoma. (medscape.org)
1989) Conservative surgery for renal cell carcinoma: a single-center experience with 100 patients. (medscape.org)
a type of conservative fertility-preserving surgery for women with cervical cancer. (sharedjourney.com)
Massive solid treatment is conservative surgery. (who.int)

labor was also delivered successfully via cesarean section. (sharedjourney.com)

Is cryonics unique or does it have anything in common with low-temperature surgery or freezing sperm or eggs? (alcor.org)
freezing embryos (fertilized eggs) is one fertility-preserving option available to women of reproductive age. (sharedjourney.com)
The eggs and sperm are then fertilized together in the laboratory and cryogenically frozen until they are ready to be implanted in the women's uterus following cancer treatment. (sharedjourney.com)
this method of fertility preservation attempts to retrieve, freeze and store unfertilized eggs for future usage. (sharedjourney.com)

After washing, sections were incubated with appropriate secondary antibody conjugated to HRP, and visualized using DAB with or without cobalt (black versus brown, respectively). (cdc.gov)

He's board certified by the American Board of Surgery in both pediatric and general surgery. (cookchildrens.org)

If the frozen section came back with suspicious results, then she would go for the full axillary dissection. (cancer.org)
To develop and validate nomogram models using noninvasive imaging parameters with related clinical variables to predict the extent of axillary nodal involvement and stratify treatment options based on the essential cut-offs for axillary surgery according to the ACOSOG Z0011 criteria. (jcancer.org)
Almost 30% clinically node negative (cN0) early breast cancers have positive nodes on pathology, wherein an axillary dissection is done as a second stage surgery. (bvsalud.org)
All cN0 women undergoing upfront surgery, who underwent low axillary sampling (LAS) with FS were included. (bvsalud.org)

If the pathologist found the sentinel nodes to be clear, surgery was over. (cancer.org)

Treatment that is given before there is any indication that the cancer has spread to prevent or delay the development of metastatic breast cancer administered after surgery and/or radiation. (ucsfhealth.org)
With the development of new surgical techniques in breast cancer, such as oncoplastic breast surgery, increased knowledge of risk factors for poor satisfaction with conventional breast-conserving surgery (BCS) is needed in order to determine which patients to offer these techniques to. (springer.com)
Hence, it is important to identify factors associated with a poor aesthetic outcome after conventional BCS, in order to determine which patients would benefit the most from oncoplastic breast surgery. (springer.com)
Adult patients with histologically proven early breast cancer (cT1-2, N0-1) who were eligible for breast-conserving surgery as per clinicoradiological assessment were included. (bvsalud.org)

The high prevalence of multinodular goiter in the countries where goiter is endemic complicates the selection of patients presenting with solitary nodules for surgery(4). (priory.com)
The patient was a 55-year-old male who was admitted to the Thyroid Surgery Department of The Affiliated Hospital of Southwest Medical University (Luzhou, China) in February 2022 due to the presence of thyroid nodules. (spandidos-publications.com)

Anti-cancer drugs used in combination with surgery and/or radiation to destroy residual cancer cells to prevent or delay recurrence. (ucsfhealth.org)
The goal of this trial was to treat prostate cancer with fewer side effects than surgery or radiation. (stanford.edu)

It is used most often in oncological surgery. (wikipedia.org)

Unsuccessful surgery with persistent hyperparathyroidism, due to inadequate preoperative or intraoperative localization, may be observed in about 10% of patients. (snmjournals.org)
For localization of OA, sections were blocked for endogenous peroxidase, washed, permeabilized with 0.05% Pepsin solution in 0.01N HCL, washed and blocked for nonspecific binding with 10% goat serum for 20 minutes. (cdc.gov)

1999) Nephron sparing surgery for localized renal cell carcinoma: impact of tumor size on patient survival, tumor recurrence and TNM staging. (medscape.org)
1997) Patterns of tumor recurrence and guidelines for followup after nephron sparing surgery for sporadic renal cell carcinoma. (medscape.org)

1 Second Department of Surgery - Ludwig Boltzmann Institute for Surgical Laparoscopy, Allgemein Offentliches Krankenhaus Linz, Austria. (nih.gov)

Surgeries revealed a 8 x7 x6cm, solid mass arising from distal ileum, separating from the adnexa and uterus of normal appearance. (researchsquare.com)
If you have not had a hysterectomy (surgery to remove the uterus), you should be given another medication called a progestin to take with topical estradiol. (medlineplus.gov)

2007) Morbidity and clinical outcome of nephron-sparing surgery in relation to tumour size and indication. (medscape.org)
The choice of Clinical or Research Microtomes from Leica Biosystems gives the precision, control, and comfort needed to get the best possible section from every block, every day. (leicabiosystems.com)
Interventions: Patients were randomized 1:1:1 to study groups: standard care including clinical explanation about surgery (control), standard care plus the Navya-PPT provided to the patient alone (solo group), and standard care plus the Navya-PPT provided to the patient and a caregiver (joint group). (bvsalud.org)

Subsequently, it is cut frozen with the microtome portion of the cryostat, the section is picked up on a glass slide and stained (usually with hematoxylin and eosin, the H&E stain). (wikipedia.org)
These three cases reported large dermatofibrosarcoma, which began as a small nodule and progressed within approximately a year and were treated subsequently with wide excisions surgery. (thieme-connect.de)

158 of 282 patients (56%) were found through H&E serial sectioning, whereas 124 of 282 patients (44%) were only seen in immunohistochemistry. (nih.gov)
2005) Elective nephron sparing surgery should become standard treatment for small unilateral renal cell carcinoma: long-term survival data of 216 patients. (medscape.org)
The earlier recognition of PHPT has increased the number of parathyroidectomies performed for PHPT, considering that about one tenth of all patients with PHPT undergo surgery in an early phase of disease. (snmjournals.org)

During surgery the common bile duct and choledochus were found to be dilated. (ispub.com)
They used to think that more surgery would stop the cancer from proceeding, but later found that totally removing all the nodes from the arm and chest (they even went for the ones between the ribs! (cancer.org)

The Internet Journal of Surgery. (ispub.com)

The hospital called the couple's claims "outrageous" and said the 25-year-old mother was given anesthesia before the emergency surgery. (buzzfeed.com)
Dr. Uffman earned his degree and completed his residency at Louisiana State University Health Sciences Center and fellowship in pediatric surgery in Memphis, Tennessee, at Le Bonheure and St. Jude Children's Research Hospital. (cookchildrens.org)

Also involved in the study were members of the departments of Electrical and Computer Engineering, and Surgery at Wayne State University in Detroit. (sciencedaily.com)

2004) Nephron sparing surgery for appropriately selected renal cell carcinoma between 4 and 7 cm results in outcome similar to radical nephrectomy. (medscape.org)

He is also a member of the American Pediatric Surgery Association, American College of Surgeons, Children's Oncology Group, Texas Medical Association, Tarrant County Medical Society, Fort Worth surgical society, Fort Worth Pediatric Society and Cook Children's Physician Network. (cookchildrens.org)

Anatomy6

Diseases18

Chemicals and Drugs9

Analytical, Diagnostic and Therapeutic Techniques and Equipment67

Phenomena and Processes3

Disciplines and Occupations9

Information Science2

Health Care15

Intraoperative frozen section6

Biopsy8

Resection8

Mohs4

Tissue17

Examination4

Tumors4

Invasive4

Mastectomy4

Formalin fixed paraffin embedded1

20181

Paraffin2

Endoscopic Surgery1

Pancreatic Surgery1

Parathyroid surgery1

Radiotherapy3

Underwent surgery2

Diagnosis2

Ovarian1

Margins2

Metastasis1

Pathological2

Procedure5

Conservative4

Cesarean1

Eggs4

Secondary1

General Surgery1

Axillary4

Pathologist1

Breast4

Nodules2

Radiation2

Oncological1

Localization2

Recurrence2

Laparoscopy1

Uterus2

Clinical3

Subsequently2

Patients3

Found2

Journal1

Hospital2

Study1

Outcome1

Surgeons1