ProteinsTumorProteinTransporterStructurally relatedMemberGenome-wideCATHTaxonomicDomainsFamiliesOrthologsFontsGenesTypefaceSequenceMembersPathwaysStructuralVersatileSpecificPagesTrueGeneralCATH SuperfamilyCadherinPhylogeneticPeptidesCharacterizationDomainsDiversityNomenclatureFunctionalStructureStructuralSearchPageAnalysisBetaSummary
Proteins15
- The Bile/Arsenite/Riboflavin Transporter (BART) superfamily is a superfamily of ubiquitous transport proteins. (wikipedia.org)
- As we show here, these RCC1 superfamily proteins can be subdivided in five subgroups based on structural criteria. (nih.gov)
- In recent years, a number of studies have been published regarding the functions of RCC1 superfamily proteins. (nih.gov)
- Here, we review the available structural and functional data on RCC1 superfamily members, paying special attention to the human proteins and their involvement in disease. (nih.gov)
- Encompassing a plethora of growth, differentiation and morphogenic factors, the Transforming Growth Factor-β (TGF-β) Superfamily is comprised of signaling proteins that have been universally conserved throughout the animal kingdom and presently consists of over forty members, the likes of which include: TGF-β isoforms, bone morphogenetic proteins (BMPs), growth differentiation factors (GDFs), activins, and inhibins. (peprotech.com)
- Noted for activating Smad signaling cascades through interactions with a conserved family of cell surface serine/threonine-specific protein kinase receptors, the complexity of TGF-β signaling has been demonstrated through the additional regulation of physiological processes by TGF-β Superfamily Ligand through non-canonical pathways, and the activation of signaling molecules other than Smad proteins. (peprotech.com)
- Given the intricacies and significance associated with the activities of TGF-β Superfamily proteins, the impairment of proper signaling has been understandably connected to a variety of clinical indications, such as tumor cell growth, fibrosis, skeletal defects, and autoimmune disease. (peprotech.com)
- Roles for transforming growth factor beta superfamily proteins in early folliculogenesis. (woodrufflab.org)
- These studies reveal important roles for the transforming growth factor beta (TGF-beta) superfamily of proteins in the ovary. (woodrufflab.org)
- TGF-beta Superfamily Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (wakehealth.edu)
- This graph shows the total number of publications written about "TGF-beta Superfamily Proteins" by people in this website by year, and whether "TGF-beta Superfamily Proteins" was a major or minor topic of these publications. (wakehealth.edu)
- Below are the most recent publications written about "TGF-beta Superfamily Proteins" by people in Profiles. (wakehealth.edu)
- Clues to the function of protein domains belonging to such a diverse superfamily can be gleaned from analysis of the proteins and organisms in which they are found. (bvsalud.org)
- also called orosomucoid) is synthesized in the liver and structurally belongs to the lipocalin superfamily of secretory proteins, such as retinol-binding protein and α1-microglobulin. (cdc.gov)
- Interleukin-1 receptor accessory protein (IL-1RAcP) is a member of the immunoglobulin superfamily proteins consisting of soluble and membranous isoforms. (lu.se)
Tumor4
- Members of the tumor necrosis factor receptor superfamily (TNFRSF) participate prominently in B-cell maturation and function. (nih.gov)
- tumor necrosis factor receptor superfamily ] Members of this family of transmembrane glycoproteins show features of the TNF receptor family. (copewithcytokines.org)
- Expression system for standard: Tumor necrosis factor receptor superfamily member 18(TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. (innov-research.com)
- Many key regulators of immune cell function belong to the so-called tumor necrosis factor superfamily (TNFSF) and their cognate receptors, the so-called TNF receptor superfamily. (apogenix.com)
Protein8
- Phylogenetic characterization of transport protein superfamilies: superiority of SuperfamilyTree programs over those based on multiple alignments. (wikipedia.org)
- MGI protein superfamily detail pages represent the protein classification set for a homeomorphic superfamily from the Protein Information Resource SuperFamily ( PIRSF ) site. (jax.org)
- You can select a given mouse superfamily member and download (or forward to NCBI BLAST) FASTA formatted protein sequences of that mouse gene and its mouse, human and rat homologs, as defined in the corresponding HomoloGene Class. (jax.org)
- You can also "Select all" mouse superfamily members to obtain their protein sequences and the protein sequences for all mouse, human and rat homologs of the mouse superfamily members. (jax.org)
- For mouse superfamily members not included in any HomoloGene Class, only the mouse protein sequence is returned. (jax.org)
- Transforming growth factor (TGF)-b1 and bone morphogenetic protein (BMP)-9 are both pleiotropic growth factors which are members of TGF-b superfamily. (gla.ac.uk)
- Bioinformatic analyses were conducted to investigate the protein structure, motif composition, chromosome location, phylogenetic relationship, and interaction network of the IiAP2/ERF superfamily genes. (jcimjournal.com)
- The NTF2-like superfamily is a versatile group of protein domains sharing a common fold. (bvsalud.org)
Transporter3
- The bile-arsenite-riboflavin transporter (BART) superfamily FEBS Journal 274(3):612-29. (wikipedia.org)
- it is a member of the ABC transporter superfamily. (medscape.com)
- The genetic landscape of the human solute carrier (SLC) transporter superfamily. (cdc.gov)
Structurally related2
- The overall goal of this project was to use the tools of physical organic chemistry to probe the mechanistic features of promiscuous enzymes in the alkaline phosphatase superfamily, a structurally related family of enzymes that appears to be particularly prone to promiscuous behaviour. (europa.eu)
- The TNFSF consists of 19 structurally related ligands, each binding to one or more of the 29 members of the TNF receptor superfamily. (apogenix.com)
Member3
- Selections return the entire set of mouse, human, and rat homologs of the mouse PIRSF superfamily member selected. (jax.org)
- And, much like the Incredibles and the Obamas, every member of a superfamily has similar DNA-resulting in related letterform structures with corresponding characteristics-but different functions. (commarts.com)
- This gene encodes a member of the TNF-receptor superfamily. (innov-research.com)
Genome-wide2
- However, few studies have investigated the genome-wide role of the AP2/ERF superfamily in Isatis indigotica . (jcimjournal.com)
- This study undertook a genome-wide characterization of the AP2/ERF superfamily in I. indigotica , providing valuable information for further functional characterization of IiAP2/ERF genes and discovery of genetic targets for metabolic engineering. (jcimjournal.com)
CATH3
- Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. (cathdb.info)
- The following diagram provides an overview of the CATH structural domains within this superfamily. (cathdb.info)
- Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. (cathdb.info)
Taxonomic1
- This Superfamily currently has 1 taxonomic siblings ( listed below ) and an expanded tree of 15 members ( self + siblings + sub-siblings ). (noaa.gov)
Domains1
- All three domains are similar in structure and all belong to the NTF2-like superfamily. (bvsalud.org)
Families2
- As of early 2016, the superfamily contains seven established families. (wikipedia.org)
- AP2/ERF (APETALA2/ethylene-responsive factor) superfamily is one of the largest gene families in plants and has been reported to participate in various biological processes, such as the regulation of biosynthesis of active lignan. (jcimjournal.com)
Orthologs1
- Computational Identification of the Paralogs and Orthologs of Human Cytochrome P450 Superfamily and the Implication in Drug Discovery. (stembook.org)
Fonts5
- Monaspace is a mix-n-match "superfamily" of monospaced fonts. (kottke.org)
- Monaspace is a mix-n-match "superfamily" of monospaced fonts designed by Github for coding. (kottke.org)
- But I remembered hearing of font "superfamilies" and that using them can shave time off this task because the similarities within each family make working with its fonts a no-brainer, eliminating time-consuming guesswork. (commarts.com)
- Typeface superfamilies are those in which the fonts in a family fall into many classifications. (commarts.com)
- I ask him if all superfamily fonts have the ability to harmonize in any situation and help me design faster. (commarts.com)
Genes2
- This study establishes a complete picture of the AP2/ERF superfamily in I. indigotica and contributes valuable information for further functional characterization of IiAP2/ERF genes and supports further metabolic engineering. (jcimjournal.com)
- To identify the IiAP2/ERF superfamily genes, the AP2/ERF sequences from Arabidopsis thaliana and Brassica rapa were used as query sequences in the basic local alignment search tool. (jcimjournal.com)
Typeface1
- Together, we choose five typeface superfamilies designed with varying personalities. (commarts.com)
Sequence1
- Despite a conserved Rossmann-fold structure, members of the SDR superfamily exhibit low sequence similarities, which constituted a bottleneck in terms of identification. (diva-portal.org)
Members2
- Mouse superfamily members are shown with links to their corresponding HomoloGene Classes. (jax.org)
- Considered vital to the modulation of cell proliferation, differentiation, matrix synthesis, and apoptosis, members of the TGF-β Superfamily are fundamental to prenatal development and the postnatal growth, remodeling, and maintenance of various tissues and organs. (peprotech.com)
Pathways1
- Many key molecules involved in these pathways belong to the TNF receptor superfamily. (apogenix.com)
Structural1
- Filling out the structural map of the NTF2-like superfamily. (bvsalud.org)
Versatile1
- 90 different styles, making it the most versatile and complete gothic superfamily. (gfxtra31.com)
Specific1
- The lung undergoes substantial growth, alveolarization, and cellular maturation within the first years of life, which may be impacted by environmental pollutants such as PM. PAHs in PM can serve as ligands for the aryl hydrocarbon receptor (AhR) that induces expression of certain isozymes in the cytochrome P-450 superfamily, such as CYP1A1 and CYP1B1, localized in specific lung cell types. (cdc.gov)
Pages1
- Michael Stinson, creative director at Ramp Creative, lays out pages typeset with superfamilies to compare and evaluate how they perform. (commarts.com)
True1
- Are superfamilies the true superheroes of type pairing? (commarts.com)
General1
- A general summary of information for this superfamily. (cathdb.info)
CATH Superfamily1
- Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. (cathdb.info)
Cadherin1
- Cadherin superfamily of adhesion molecules in primary lung cancer. (nih.gov)
Phylogenetic1
- Bayesian inference (BI) method-based phylogenetic tree for three superfamilies in Ditrysia (Tineoidea, Gracillarioidea, and Yponomeutoidea) obtained using concatenated sequences of 13 PCGs and 2 rRNAs. (mendeley.com)
Peptides1
- The secretin/PACAP/VIP superfamily contains at least ten brain-gut peptides, including secretin, pituitary adenylate cyclase-activating polypeptide (PACAP), vasoactive intestinal polypeptide (VIP), glucagon, glucagon-like peptide-1 (GLP-1), glucagon like peptide-2 (GLP-2), gastric inhibitory polypeptide (GIP), peptide histidine isoleucine (PHI) or peptide histidine methionine (PHM), and growth hormone-releasing hormone (GHRH). (eurekaselect.com)
Characterization1
- Bioinformatic characterization of the Anoctamin Superfamily of Ca2+-activated ion channels and lipid scramblases. (tcdb.org)
Domains1
- All three domains are similar in structure and all belong to the NTF2-like superfamily. (bvsalud.org)
Diversity2
- [ 24-26 ] Nevertheless, to the best of our knowledge, no study has focused on the entire CYP450 superfamily, investigating the functional diversity of human populations and identifying the most differentiated genes. (medscape.com)
- Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. (cathdb.info)
Nomenclature1
- This revision supersedes the four previous updates in which a nomenclature system, based on divergent evolution of the superfamily, has been described. (nih.gov)
Functional3
- Our aim is to investigate the functional structure of the CYP450 superfamily in humans, to identify the most differentiated CYP450-related health aspects, and to analyze the role of CYP450 in human adaptation. (medscape.com)
- One functional CYP51 gene and two processed pseudogenes, which are the first examples of intronless pseudogenes within the P450 superfamily, have been mapped to three different human chromosomes. (nih.gov)
- This study provides a broad molecular perspective relevant for future functional and therapeutic studies of the diverse cancer pathways mediated by the TGF-β superfamily. (nih.gov)
Structure1
- A vast knowledge of the structure of the Cys-loop superfamily and its impact on channel function have been accrued over the last few years, leading to exciting new proposals on how ion channels open and close in response to agonist binding. (portlandpress.com)
Structural1
- Filling out the structural map of the NTF2-like superfamily. (bvsalud.org)
Search1
- Thankfully, the London type foundry Peregrin Studio has simplified the search with their font Denton Superfamily. (printmag.com)
Page1
- To join the TGF-beta Superfamily Interest Group mailing list, please visit the TGF-beta Superfamily Interest Group Listserv home page , then click the "Subscribe or Unsubscribe" link in the right sidebar. (nih.gov)
Analysis1
- A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily. (nih.gov)
Beta2
- The TGF-beta superfamily occupies a central position in the signaling circuits that control cell growth, differentiation, and death. (nih.gov)
- The TGF-beta Superfamily Interest Group keeps abreast of advances in the field of TGF-beta superfamily research and in our understanding of the global ramifications when TGF-beta signaling goes awry in diseases such as cancer, diabetes, obesity, immunological disorders, and pathological fibrosis. (nih.gov)
Summary1
- A general summary of information for this superfamily. (cathdb.info)