For the chemosensitivity for carcinoma of digestive organs, gastric, colorectal, and hepatic cancer tissues were examined using in vitro succinate dehydrogenase inhibition (SDI) test and in vivo subrenal capsule (SRC) assay. (elsevierpure.com)
Inside a transwell assay (Fig.?2a), both anti-CAIX mAbs G37 and G119 showed inhibition of RCC cell migration much like that seen using the CA inhibitor acetazolamide. (monossabios.com)
Likewise, both mAbs demonstrated a capability to inhibit RCC development in wound curing assays (Fig.?2b) that mirrored inhibition seen with acetazolamide treatment [29]. (monossabios.com)
Tumor1
Gross inspection of tumors in the terminal period point (day time 32) (Fig.?6a, smaller -panel) and dimension of tumor mass (Fig.?6b) demonstrated that control mice had substantially bigger tumor burden that broke free from the subrenal capsule to appose the stomach wall, 927880-90-8 IC50 even though mice treated with anti-CAIX mAbs had tumors that remained mounted on the kidney parenchyma. (monossabios.com)
Human tumor1
6. The antiproliferative effects of fluoropyrimidine derivatives against human tumor xenografts in a subrenal capsule assay. (nih.gov)
Tumor growth1
5. Stratton JA, Rettenmaier MA, Braly PS, DiSaia PJ: Accurate prediction of tumor growth in vivo: The subrenal capsule implant site. (scgynoncology.com)
Chemosensitivity3
1. [Chemosensitivity of head and neck squamous cell carcinomas using subrenal capsule assay--comparative assay of 5-FU, FT, UFT, and HCFU and immunohistochemical study]. (nih.gov)
4. [Chemosensitivity testing for 5-FU and 5-FU derivatives using subrenal capsule assay]. (nih.gov)
3. Stratton JA, Rettenmaier MA, Berman ML, DiSaia PJ: The response of gynecologic tumors to chemotherapy: Correlation of the chemosensitivity predicted by the subrenal capsule implant assay with the clinical response of the patients. (scgynoncology.com)
Vivo1
Método in vivo de cribado de medicamentos anticancerosos en investigación y de modificadores de respuesta biológica para pacientes con cáncer. (bvsalud.org)
Test2
2. Sensitivity test for 5-fluorouracil and its analogues, 1-(2-tetrahydrofuryl)-5-fluorouracil, uracil/1-(2-tetrahydrofuryl)-5-fluorouracil (4:1) and 1-hexylcarbamoyl-5-fluorouracil, using the subrenal capsule assay. (nih.gov)
7. [Results of the UFT sensitivity test using human urogenital cancers transplanted subcutaneously and under the subrenal capsule of nude mice]. (nih.gov)