• A registry for persons treated with bedaquiline is being implemented by Janssen Therapeutics to track patient outcomes, adverse reactions, laboratory testing results (e.g., diagnosis, drug susceptibility, and development of drug resistance), use of concomitant medications, and presence of other comorbid conditions. (cdc.gov)
  • While the 5 mg dose added an increment of effectiveness, it caused an unacceptable increase in adverse reactions. (nih.gov)
  • Controlled clinical trials in patients with mild to moderate hypertension who were receiving a thiazide-type diuretic have defined the dose-response relationship for blood pressure response and adverse reactions of guanfacine given at bedtime and have shown that the blood pressure response to guanfacine can persist for 24 hours after a single dose. (nih.gov)
  • While most of the effectiveness of guanfacine in combination (and as monotherapy in white patients) was present at 1 mg, adverse reactions at this dose were not clearly distinguishable from those associated with placebo. (nih.gov)
  • Patients should be monitored carefully for adverse reactions, especially nervous system symptoms related to efavirenz (see sections 4.3 and 4.4). (who.int)
  • Multiple sport activities require the athlete to react quickly to a stimuli and the speed of the reaction can make a difference in being successful or failing. (thesportjournal.org)
  • They were attempting to discover how long an individual had to be exposed to a stimulus to perceive it consciously and how close in time two stimuli had to be to be perceived as one continuous sensation. (scientificamerican.com)
  • OBSERVATION PROCEDURE: Ability to divide attention was investigated by measuring reaction times to peripheral stimuli (at low, medium, or high contrast) while concomitantly performing a central driving task (car following or curve negotiation). (bvsalud.org)
  • Certain of the SCBA stressors significantly increased the time to perform a simulated mine escape. (cdc.gov)
  • The minnows' reaction time was significantly slowed compared to control larvae. (scitechdaily.com)
  • Peripheral leucocytes from subjects with poor sleep quality expressed significantly lower transcript levels of BMAL1 and PER1 compared with those with good sleep quality. (hindawi.com)
  • The PPI dendrimer encapsulated Cu ions in the internal nanovoids to form adjacent Cu species, which exhibited significantly high catalytic activity for the regioselective coupling reaction of DMP compared to previously reported enzyme and metal complex catalysts. (mdpi.com)
  • RNFL thickness remained significantly associated with reaction times even after adjusting for age, SAP mean deviation in the better eye, cognitive ability, and central driving task performance. (bvsalud.org)
  • Defined as the interval of time between the presentation of a stimulus to the onset of a response, reaction time as a proxy of the speed of central nervous system events has allowed researchers to reveal underlying mechanisms of information processing control. (uwaterloo.ca)
  • Studies of the acoustic startle response and of its inhibition by the presentation of a non-startling preliminary stimulus (prepulse inhibition, PPI) have revealed deficits in PPI in schizophrenic subjects compared to healthy controls. (nih.gov)
  • Unlike in the non-roving task, subjects had to take note of the contrast of the sample stimulus in order to perform the roving task correctly. (researchgate.net)
  • Measured this way, however, the reaction time includes not only the interval it takes for the eye and brain to process the stimulus but also how long it takes for the desired motor response--pressing the button. (scientificamerican.com)
  • RESULTS: The mean reaction times to the low-contrast stimulus were 1.05 s and 0.64 s in glaucoma and controls, respectively, during curve negotiation (P (bvsalud.org)
  • Nine recreationally trained subjects (5 males, 4 females) performed single-step choice reaction time trials using the Makoto Arena II testing device, following either a dynamic warm up or static stretching protocol chosen at random for all participants. (thesportjournal.org)
  • During that time, nearly two-thirds of the participants consuming AmaTea® Max reported an increase in vigor (defined as sensations of energy, effort, and enthusiasm) after one hour of gameplay. (nutraingredients-usa.com)
  • We have an ethical obligation to report results, and this is especially true when volunteers contribute their time as study participants in prospective experiments, whether large or small. (nih.gov)
  • These undetected errors also delayed participants' reaction times to the tones. (sciencedaily.com)
  • The primary aim of this work was to explore the factors that contribute to such between-subject variability in young health adults to determine if differences were reflective of trait differences or simply random fluctuations across repeated testing and task conditions. (uwaterloo.ca)
  • Furthermore, while this study relied heavily on central tendency it was also found that analyzing the distribution of reaction times also revealed important within subject variability. (uwaterloo.ca)
  • Alternative expressions of reaction time, such as variability and distribution, are also likely to be important to understanding between subject differences that is not revealed by traditional central tendency measures. (uwaterloo.ca)
  • Specifically, this study investigated the performance of visual and tactile reaction time tasks over two sessions to capture the day to day stability and task generalizability of reaction time. (uwaterloo.ca)
  • ICC results demonstrated that reaction time of individuals were more closely related between days than between individuals for a range of tasks that differed in modality (visual and tactile) and difficulty levels (simple and choice). (uwaterloo.ca)
  • Interestingly, reaction time performance was found to have a stronger association between tasks of varying difficulty but not across task modality. (uwaterloo.ca)
  • Bader - So we have seen significant improvements on two tasks in terms of faster reaction time and video gamers, better performance in terms of impulse control, and also better performance in tasks involving working memory accompanied by changes in brain function and regions of the brain involved in vision, attention, problem solving and memory processing. (thenakedscientists.com)
  • A total of 36 healthy right-handed male subjects performed four distinct cognitive tasks: spatial item recognition, verbal item recognition, and two spatial compatibility tasks. (nih.gov)
  • All subjects performed the tasks under three exposure conditions: right side, left side, and sham exposure. (nih.gov)
  • In this study, reaction times (RT) of 6 volleyball players and 6 non sports practitioners were compared during voluntary and automatic orienting of attention tasks. (bvsalud.org)
  • The nature and structure of the reaction intermediates during the recombination are determined, elucidating the full mechanism of photodissociation and recombination on ultrafast time scales. (lu.se)
  • The idea is instead that perceptual organization involves the coming together of interdependent processes that operate on different time scales, including processes in neurophysiology, motor behavior, attention, and intention. (frontiersin.org)
  • A study shows that children that play video games have better reaction times than those that do not. (thenakedscientists.com)
  • The purpose of the study was to determine whether a dynamic warm up or static stretching had a greater impact on choice reaction time. (thesportjournal.org)
  • thus presenting the need for research to study actual choice reaction and not just reaction from a force plate. (thesportjournal.org)
  • Due to the lack of literature in the area of actual choice reaction time it became apparent a pilot study needed to be conducted in order to develop an adequate methodology to allow for future research. (thesportjournal.org)
  • The study included nine subjects, five males and four females, ages ranging from 24-56 years old. (thesportjournal.org)
  • In the current study the effects on PPI of the atypical antipsychotic olanzapine and the typical antipsychotic haloperidol were compared to the unmedicated state in subjects with schizophrenia. (nih.gov)
  • The subjects were solicited through the NCCC secretary, who was not part of the research team, and their names were not turned over to us until they had accepted our offer to participate in the study. (cdc.gov)
  • In one study, research subjects were allowed to sleep for five hours per night for a week. (sleepfoundation.org)
  • Throughout the gaming study, subjects took baseline measurements and then played the game Fortnite for four one-hour periods. (nutraingredients-usa.com)
  • The study was performed in an 83 m3 stainless steel climate chamber with four subjects per day exposed six hours to either 0, 10, 35, or 100 uL/L pure n-decane. (europa.eu)
  • To avoid bias arising both from the investigator and from the participating subjects, a double blind design was used in the study. (europa.eu)
  • Enzyme kinetics is the study of the rates of enzyme-catalysed chemical reactions . (wikipedia.org)
  • The subjects for the study included healthy male volunteers: four carbon-dioxide (124389) (CO2) sensitive, four young and fit, and four miners. (cdc.gov)
  • In the study, eighteen (11.2 percent)) subjects had plasma cholinesterase activity higher than the upper limit of the normal range (1700-4100 U/L) of plasma cholinesterase activity. (who.int)
  • In the study, seven (4.3 percent) subjects had Erythrocyte cholinesterase activity higher than the upper limit of the normal range. (who.int)
  • 4400-8200 U/L). In the present study, none of the subjects had plasma cholineserase activity and Erythrocyte cholinesterase activity lower than the normal range. (who.int)
  • PATIENT POPULATION: Total of 158 subjects from the Diagnostic Innovations in Glaucoma Study, including 82 with glaucoma and 76 similarly aged controls. (bvsalud.org)
  • METHODS: The study received institutional review board approval, and informed consent was obtained from all subjects. (bvsalud.org)
  • This study investigated the effect of cooling on the physiological responses and probability of hyperthermia in subjects wearing FPC during exercise in a hot environment. (cdc.gov)
  • 97 subjects completed the study. (medscape.com)
  • Physiological reactions to the exposure were measured in the external eye by the tear film stability test, a photographic test of changes in eye redness, and by a cytological evaluation of tear secretion.Test procedures were as follows. (europa.eu)
  • Subjects' physiological responses increased during exercise in a warm and humid environment. (cdc.gov)
  • For the Modi apologists, their hero didn't say the post-Godhra massacres were a 'reaction' but they believe the Muslims who got killed in 'reaction' had it coming anyway. (blogspot.com)
  • The Reaction saw the Left suppressed by brutal force , including massacres, as well as the disbanding of the Jacobin Club , the dispersal of the sans-culottes , and the renunciation of the Montagnard ideology. (wikipedia.org)
  • Transcript levels of circadian clock genes ( BMAL1 , PER1 , PER2 , and PER3 ) were determined by real-time quantitative polymerase chain reaction. (hindawi.com)
  • Very soon, your answer will be crucial to picking the appropriate NIH funding opportunity for your application, writing your research plan correctly (since some information will be captured in the new human subjects and clinical trials form ), and ensuring that your application includes all the information required for peer review. (nih.gov)
  • Delta-9 is the quintessential form of THC that has been the subject of clinical trials for everything from multiple sclerosis to memory retrieval. (stradanove.net)
  • Clinical Trials in Radiology 2 When: Thursday 2 March 2 Time: 12:30 - 13:30 Room: M 1 5. (stradanove.net)
  • In addition, subjects on psilocybin exhibited particularly slow reaction times in invalid trials at short cue target intervals and failure of response inhibition in valid trials at long cue target intervals for right visual field targets. (erowid.org)
  • Peripheral leucocytes were sampled from 81 subjects with diabetes and 28 normal controls at 09:00. (hindawi.com)
  • Furthermore, mRNA expression of circadian clock genes is dampened in peripheral leucocytes of subjects with poor sleep quality. (hindawi.com)
  • The static stretching (SS) and dynamic warm up (DWU) protocols the subjects performed lasted ten minutes in duration and were preceded with baseline testing of a sit and reach and a single-step choice reaction time trial. (thesportjournal.org)
  • However, it should be noted that although both SS and the DWU resulted in significance, the greatest difference in the speed for the choice reaction time was found with the baseline to DWU. (thesportjournal.org)
  • We consider evolutionary reaction-diffusion problems with mixed Dirichlet--Robin boundary conditions. (aimsciences.org)
  • Yet in an instant on the evolutionary time scale, Edison's invention of the light bulb, and his opening of the first round-the-clock power plant on Pearl Street in Manhattan in 1882, shifted our time-and-light environment in the nocturnal direction. (harvardmagazine.com)
  • So the video gaming questionnaire is part of a larger screen time questionnaire that asks kids how many hours they spent on consoles or playing mobile phone or any other device. (thenakedscientists.com)
  • Cognitive ability was assessed using the Montreal Cognitive Assessment and subjects completed a driving history questionnaire. (bvsalud.org)
  • Outcomes from this work will help to inform and contribute in supporting the use of reaction time as a stable predictor of central nervous system processing speed to indicate declining or improving performance. (uwaterloo.ca)
  • DNA results found no association between APOE or COMT allele and reaction time performance. (uwaterloo.ca)
  • The results from this thesis support the importance of stable, person-specific traits in determining reaction time while also emphasizing the potential impact of state factors. (uwaterloo.ca)
  • The results indicated that the exposure of the left side of the brain slows down the left-hand response time, in the second-later-part of the experiment. (nih.gov)
  • The conventional PCR method and real-time PCR results were comparable in all but one case, where the discrepancy was attributed to sample-specific degradation. (bvsalud.org)
  • The studies of the Dibuvcaine inhibition of subjects showed that there were cholinesterase variants in the Kurunegala and Kegalle districts. (who.int)
  • Using a patented process to enhance the naturally occurring antioxidants and caffeine from guayusa leaves, AmaTea® Max may help improve cognitive performance by increasing mental focus, stamina, and reaction time with fewer jitters than other forms of caffeine. (nutraingredients-usa.com)
  • Serial choice visual reaction time (SCRT) was used as a measure of cognitive performance. (cdc.gov)
  • It may be time to reconsider some teaching strategies, especially how adults are taught a second language, said Neville, a member of the UO's Institute of Neuroscience and director of the UO's Brain Development Lab. (sciencedaily.com)
  • Ribozymes also perform a more limited set of reactions, although their reaction mechanisms and kinetics can be analysed and classified by the same methods. (wikipedia.org)
  • If the patient misses a dose and it is less than 12 hours after it was due, the patient should be advised to take the dose as soon as possible and then take the next dose at the scheduled time. (who.int)
  • If more than 12 hours have passed since the dose was due, the patient should omit the missed dose and take the next scheduled dose at the usual time. (who.int)
  • For well over a century reaction time has provided researchers with a method to quantify information processing speed. (uwaterloo.ca)
  • Today researchers flash a small black bar on a computer screen and ask subjects to press a button as soon as they recognize whether the bar is vertical or horizontal. (scientificamerican.com)
  • In cases where subjects correctly declared errors in sentences, the researchers found a P600 effect, an ERP response in which the error is recognized and corrected on the fly to make sense of the sentence. (sciencedaily.com)
  • In enzyme kinetics, the reaction rate is measured and the effects of varying the conditions of the reaction are investigated. (wikipedia.org)
  • In a simulation of an emergency escape from a mine, each subject performed a 2 mile maximal exertion run on a treadmill ergometer under nine conditions: control, resistance breathing (RB), CO2, positive pressure breathing (PPB), hot air breathing (HAB), CO2+RB, HAB+RB, HAB+CO2, and HAB+CO2+RB. (cdc.gov)
  • The reactivity of aromatic and aliphatic aldehydes was evaluated under Sakurai reaction conditions. (purdue.edu)
  • All aldehydes were subjected to the same reaction conditions and reaction times. (purdue.edu)
  • Prior to use, the doctor must ascertain the status of circulatory conditions of the subjects to be treated. (janusinfo.se)
  • But sleep is not merely "down time" between episodes of being alive. (harvardmagazine.com)
  • this substance can cause allergy-like reactions and serious episodes of asthma in sensitive subjects and especially in asthmatics. (janusinfo.se)
  • As we go into the last quarter of 2018, it really is time to begin thinking about exactly how things have actually altered, where points are going, and also what you can do to ensure your SEO initiatives stay effective. (liveinternet.ru)
  • Such cases exist: for example, a mutase such as phosphoglucomutase catalyses the transfer of a phospho group from one position to another, and isomerase is a more general term for an enzyme that catalyses any one-substrate one-product reaction, such as triosephosphate isomerase . (wikipedia.org)
  • This rate-determining step may be a chemical reaction or a conformational change of the enzyme or substrates, such as those involved in the release of product(s) from the enzyme. (wikipedia.org)
  • in such cases, it is helpful to determine the enzyme structure with and without bound substrate analogues that do not undergo the enzymatic reaction. (wikipedia.org)
  • Beyond this limit the enzyme is saturated with substrate and the reaction rate ceases to increase. (wikipedia.org)
  • The reaction catalysed by an enzyme uses exactly the same reactants and produces exactly the same products as the uncatalysed reaction. (wikipedia.org)
  • Subjects were given 280 experimental sentences, including some that were syntactically (grammatically) correct and others containing grammatical errors, such as "We drank Lisa's brandy by the fire in the lobby," or "We drank Lisa's by brandy the fire in the lobby. (sciencedaily.com)
  • Subjects participated in two randomly counterbalanced assigned experimental protocols: control (no cooling) and intervention (cooling). (cdc.gov)
  • Update September 2017: It's eight years since I first braved this subject, expecting a snowstorm of protest. (moneysavingexpert.com)
  • Genetic samples and nerve conduction velocity were also collected to speculate on potential biological markers that may relate to reaction time performance. (uwaterloo.ca)
  • Potentially, tracking reaction time performance may be important in identifying potential risk of injury related to decreased speed of processing or as a marker of improved performance in training. (uwaterloo.ca)
  • The differences in reaction time between individuals is an interesting phenomenon that is sometimes disregarded as biological noise but could reveal further insight into the determinants of central nervous system speed of processing. (uwaterloo.ca)
  • It reveals how nicely you perceive this subject. (sixthseal.com)
  • On the other hand, NCCs might build up over a longer time until they intrude into our awareness and may then only slowly fade until they are so slight that we can no longer perceive them. (scientificamerican.com)
  • In some emergencies, in which there is no time for diagnostic tests, surgery is used for both diagnosis and treatment. (msdmanuals.com)
  • With the real-time PCR method , 10 of the severe haemophilia A patients and 3 carriers tested inv22-positive. (bvsalud.org)
  • Before exposure three tests were performed to measure subject sensitivity. (europa.eu)
  • The subjective reactions to the exposure were measured by questionnaires and a linear potentiometer. (europa.eu)
  • Structural analysis of the scattering data resolves the solvent-dependent structural evolution during the bond cleavage, internal rearrangements, solvent-cage escape, and bond reformation in real time. (lu.se)
  • The current article will present the impact of the heat and mass transfer of combine electrical MHD flow of time dependent Williamson fluid with nanoparticles by the incorporating the influences of non-linear thermal radiation and the chemical reaction through wedge shape geometry. (scienceopen.com)
  • The number of tests conducted was the highest in the world at the time and exceeded those conducted by China and Italy, the 2 countries with the highest number of COVID-19 patients. (frontiersin.org)
  • Bartlett, J 2004, ' Quantification of the influenza virus load by real-time polymerase chain reaction in nasopharyngeal swabs of patients treated with oseltamivir ', Infectious Diseases in Clinical Practice , vol. 12, no. 2. (johnshopkins.edu)
  • A maximal graded treadmill exercise test was performed to measure maximal oxygen uptake (VO(2max)) and to assess subjects' capacity to perform the assigned exercise. (cdc.gov)
  • We have recorded the reaction times (RTs) and accuracy of the responses. (nih.gov)
  • In response to questioning after completion of the tests, nine of the 12 subjects reported difficulty breathing in the triple stressor condition, eight during RB alone, seven during HAB+RB, six during CO2+RB, and six during PPB. (cdc.gov)
  • As early as the 19th century, psychologists exposed test subjects to flashes of light that varied in duration and intensity. (scientificamerican.com)
  • Subjects reported strength and duration of the sensation on either cheek within the following 10 minute period. (europa.eu)
  • We screened for inv22 with our previously reported conventional polymerase chain reaction ( PCR ) method , as well as with a newly developed real-time PCR method . (bvsalud.org)
  • Humans are living longer today than at any other time in history, and attention is increasingly focused on problems that arise from improved longevity, including a progressive cognitive weakening over the course of aging. (jneurosci.org)
  • MAIN OUTCOME MEASURES: Reaction times to the driving simulator divided attention task. (bvsalud.org)
  • Reaction is basically a reflex based drinking game with an electric shock delivered to the slower (or more intoxicated) players. (sixthseal.com)
  • In Kegalle distirct, the mean Erythrocyte cholinesterase avtivity of subjects was 6257 U/L with the standard deviation of 903. (who.int)
  • In one experiment, subjects were asked to decide quickly whether an image that flashed on a screen for fractions of a second contained an animal or not. (scientificamerican.com)
  • DWU had a greater impact on a single step choice reaction time and thus should be considered as an element to be incorporated into any athletic training program to enhance athletic achievement. (thesportjournal.org)
  • Although DWU has been demonstrated to improve speed and power, very little research has been done to show a DWU has the same effect with reaction time, and no research has utilized a single step choice reaction format. (thesportjournal.org)
  • Therefore with the convincing literature regarding DWU and SS, our hypothesis was that the DWU would produce a quicker choice reaction time as opposed to a traditional SS procedure. (thesportjournal.org)
  • The only variables in the reactions were the use of aliphatic or aromatic aldehydes or the choice of bulky protecting groups on the large silyl species. (purdue.edu)
  • Elective surgery, such as replacement of a knee joint, can be delayed for some period of time until everything has been done to optimize a person's chances of doing well during and after the surgical procedure. (msdmanuals.com)
  • These 41 subjects with schizophrenia were compared to a group of 21 historical healthy controls and found to have reduced PPI. (nih.gov)
  • Sleep disorder is associated with insulin resistance and impaired glucose tolerance in multiple metabolic pathways in healthy subjects or in subjects with diabetes [ 6 ]. (hindawi.com)
  • A double-blind, placebo-controlled trial compared the effects of two different forms of niacin - nicotinic acid and xanthinol nicotinate - on memory in 96 healthy subjects, who were either young (35-45 years), middle aged (55-65 years), or elderly (75-85 years). (life-enhancement.com)
  • In the case of the covid vaccination, fewer than 100 people in the entire world have suffered a serious clotting reaction, and about 1 in 50,000 young men have the heart reaction (It's not common in other groups), with about 1 in 500,000 being serious enough to be a problem. (abovetopsecret.com)
  • Resolving the structural dynamics of bond breaking, bond formation, and solvation is required for a deeper understanding of solution-phase chemical reactions. (lu.se)
  • Is our perception really as continuous as it seems, or is it divided into discrete time parcels, similar to frames in a movie? (scientificamerican.com)
  • After larvae were exposed to estradiol, they were subjected to sudden vibration, similar to the ones produced by approaching predators. (scitechdaily.com)
  • This takes a bit of getting used to (though it is similar to the way webpages are marked up in HTML), but in the longer term LaTeX is a major time-saver-the APA styles are quite complex, and it can be difficult to remember what items are required on the title page, what format subheadings should have, and so on. (opensource.com)
  • Reaction times increase as a person accumulates sleep debt Trusted Source National Library of Medicine, Biotech Information The National Center for Biotechnology Information advances science and health by providing access to biomedical and genomic information. (sleepfoundation.org)
  • In a between-group design, 11 schizophrenic subjects on olanzapine, 16 subjects on haloperidol, and 14 subjects who were on no medication received acoustic startle testing with PPI determination. (nih.gov)
  • Windy City Media Group publishes Windy City Times, The Bi-Weekly Voice of the Gay, Lesbian, Bisexual and Trans Community. (windycitytimes.com)
  • Group discussions were held several times to reach consensus on the level of overall risk and the evidence that supported this level of risk. (who.int)
  • control group:Routine rehabilitation training (hemiplegic limb comprehensive training, orthostatic balance, and center of gravity transfer), once a day, 40 minutes per session, 5 times a week, for a total of 4 weeks. (who.int)
  • Interactive motor cognition combined training group:The subject stands in a square corner (50cm X 50cm), and the experimenter adjusts the computer to issue numerical instructions based on the patient s reaction time. (who.int)
  • motor training group:The subject stands in a square corner (50cm X 50cm) and performs forward, backward, left, right, and diagonal step training in sequence. (who.int)
  • Nicotinic acid was of greater benefit to younger and middle-aged subjects, who showed remarkable short-term memory improvements. (life-enhancement.com)
  • We have 2000 subjects in total, kids who never played video games and kids who played video games. (thenakedscientists.com)
  • The mean (±SD) total follow-up time was 7.9 ± 4.7 months. (bvsalud.org)
  • On the basis of regular rehabilitation training once a day, 40 minutes per session, 5 times a week, for a total of 4 weeks, a combination of exercise cognition training is conducted weekly under the guidance of professional personnel, with each training lasting 10-15 minutes. (who.int)