• absent
  • Adverse events are defined as any unfavorable and unintended diagnosis, symptom, sign (including an abnormal lab finding), syndrome or disease which either occurs during study, having been absent at baseline, or, if present at baseline, appears to worsen. (clinicaltrials.gov)
  • However, other semen markers, such as gamma-glutamyltransferase, are completely absent from pre-ejaculate fluid. (wikipedia.org)
  • liver
  • A limited number of studies have reported associations of markers of liver injury, including elevated concentrations of aspartate aminotransferase (AST) and alanine aminotransferase (ALT), with prospective risk of type 2 diabetes. (diabetesjournals.org)
  • However, only one study has adjusted for a detailed measure of insulin sensitivity (insulin sensitivity index [ S i ]), which is important given associations of obesity and S i with nonalcoholic fatty liver disease (NAFLD). (diabetesjournals.org)
  • Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. (sanger.ac.uk)
  • The purpose of this study is to understand the potential of a low sugar diet for the treatment of nonalcoholic fatty liver disease (NAFLD) in children. (clinicaltrials.gov)
  • Data from clinical studies also support an effect of metadoxine on reducing indices of liver cell necrosis and fat accumulation in alcoholic fatty liver. (wikipedia.org)
  • Unwanted side effects include dizziness, reversible cholestatic jaundice, pseudoallergic reaction, and elevated levels of liver enzymes (transaminases and gamma-glutamyltransferase). (wikipedia.org)
  • substantial
  • Dr. Johnson had studied medicine at Howard University College of Medicine and faced substantial discrimination in his medical career, being turned away from active duty during the Battle of the Bulge, despite being a first lieutenant and trained physician. (wikipedia.org)
  • levels
  • RESEARCH DESIGN AND METHODS -This study included 2,957 metabolic syndrome-free men and 3,260 nondiabetic men aged 35-59 years who did not have medication for hepatitis, alanine aminotransferase (ALT) levels higher than three times the upper limit of the reference range, or a history of cardiovascular disease at study entry. (diabetesjournals.org)
  • Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men. (sanger.ac.uk)
  • Low levels or no sperm exists in pre-ejaculate, although studies examined small samples of men. (wikipedia.org)
  • Stroke
  • gamma-Glutamyltranspeptidase and incident stroke among Japanese men and women: the Circulatory Risk in Communities Study (CIRCS). (semanticscholar.org)
  • Relationship between blood pressure category and incidence of stroke and myocardial infarction in an urban Japanese population with and without chronic kidney disease: the Suita Study. (semanticscholar.org)
  • Prospective studies ( 2 , 3 ) have shown a significant relationship between serum GGT and the development of specific conditions including coronary heart disease (CHD) and stroke. (diabetesjournals.org)
  • Although the reliability and validity of self-reported alcohol drinking habits, ie, the extent to which accurate information is provided by the respondent, has often been debated, 4 5 most studies on the relation of alcohol to stroke risk have relied on self-reported alcohol drinking. (ahajournals.org)
  • In the present article we report the results from the prospective study of a random sample of middle-aged Finnish people about the relation of self-reported alcohol drinking and serum GGT concentration to the risk of stroke. (ahajournals.org)
  • kidney
  • The study evaluated the nephroprotective potentials of methanolic extract (ME) and dichloromethane fraction (DCMF) of root-bark of Garcinia kola on gentamicin-induced nephrotoxicity in rats with a view to utilize the extracts of the root of G. Kola in the amelioration of antibiotic-induced kidney damage. (academicjournals.org)
  • vitro
  • An in vitro study showed that Acivicin at a concentration of 5 µM Acivicin inhibited by 78% the growth of human pancreatic carcinoma cells (MIA PaCa-2) after 72 hours in continuous culture. (wikipedia.org)
  • clinical
  • Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. (clinicaltrials.gov)
  • The remaining 8 patients not accounted for in the treated set were removed from all study analyses (explained in trial report) due to major good-clinical-practice violations at the site, and the inability to verify the validity of any patient level data. (clinicaltrials.gov)
  • high
  • Metadoxine is a selective antagonist of the serotonin receptor subtype 5-HT2B and displays high affinity to the gamma-aminobutyric acid (GABA) transporter. (wikipedia.org)
  • dietary
  • However, it also highlights the need for more large-scale studies, including detailed dietary assessment to further advance the understanding of the impact of chrono-nutrition on public health. (cambridge.org)
  • results
  • Study record managers: refer to the Data Element Definitions if submitting registration or results information. (clinicaltrials.gov)
  • In 2009, a Canadian-led group of investigators reported in the New England Journal of Medicine results from the first PBC genome-wide association study. (wikipedia.org)
  • metabolism
  • Chrono-nutrition involves studying the impact of nutrition on metabolism via circadian patterns, including three aspects of time: (ir)regularity, frequency and clock time. (cambridge.org)
  • research
  • Studying irregular meal patterns fits in with the latest research focusing not only on what people eat but also when they eat, also called chrono-nutrition. (cambridge.org)
  • To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. (clinicaltrials.gov)
  • extract
  • The study involved preparation of the extract, fractionation, phytochemical screening and evaluation of phenolics and flavonoid contents. (academicjournals.org)
  • The extract and DCMF did not elicit any adverse effect and a dose of 250 mg/kg bwt of ME and DCMF was selected for further studies. (academicjournals.org)
  • The study concluded that, both the extract and fraction of G. kola root-bark elicited antioxidant and appreciable nephroprotective potentials. (academicjournals.org)
  • Upon studying calcium oxalate nucleation, ammi visnaga extract as a whole was shown to prolong nucleation time as well as change stone conformation, while khellin alone had no effect. (wikipedia.org)