• It will help attendees understand difference between calibration and precision, components of gage capability, procedure for a gage reproducibility and repeatability study and much more. (complianceonline.com)
  • Measurement systems analysis (MSA), or gage reproducibility and repeatability (R&R) measures the precision. (complianceonline.com)
  • Measurement systems analysis (MSA) returns a gage's repeatability and reproducibility in terms of standard deviations. (complianceonline.com)
  • Combination of the repeatability and reproducibility return the gage's overall standard deviation, which is in turn reflected by its precision/tolerance (P/T) ratio. (complianceonline.com)
  • Reproducibility, closely related to replicability and repeatability, is a major principle underpinning the scientific method. (wikipedia.org)
  • Replicability and repeatability are related terms broadly or loosely synonymous with reproducibility (for example, among the general public), but they are often usefully differentiated in more precise senses, as follows. (wikipedia.org)
  • Three tests of a single vehicle model were conducted at three different test facilities, a total of nine tests, to evaluate repeatability and reproducibility. (sae.org)
  • The responses of the vehicle and its occupants were evaluated using three different methodologies to quantify the repeatability within a single test facility and reproducibility among the three test facilities. (sae.org)
  • Saunders, J. and Parent, D., "Repeatability and Reproducibility of Oblique Moving Deformable Barrier Test Procedure," SAE Technical Paper 2018-01-1055, 2018, https://doi.org/10.4271/2018-01-1055 . (sae.org)
  • Objective -To evaluate left atrial phasic function in healthy dogs by means of 2-D speckle tracking echocardiography with time-left atrial area curve analysis and to assess repeatability and reproducibility of obtained measurements. (avma.org)
  • repeatability and reproducibility of measurements were adequate in healthy dogs. (avma.org)
  • Both intraobserver and interobserver reproducibility by QPRODIT 5.2 were good. (nih.gov)
  • 7 We have assessed the validity of volumetric measurements using a near focus transducer on a Doppler ultrasound phantom and determined the intraobserver and interobserver reproducibility of right common carotid artery (CCA) flow in newborn infants. (bmj.com)
  • Here, we have developed and performed preanalytical studies to assess the impact of the variability in scanning speed and in vendor-specific γ-camera on reproducibility and accuracy of the automated bone scan index (BSI). (snmjournals.org)
  • My lab has developed a protocol to easily assess the specificity of antibodies-and hopefully stem some of the reproducibility crisis. (the-scientist.com)
  • To assess the reproducibility of, and determine normative data for, flow volume measurements from the right common carotid artery (CCA) and its relation to left ventricular output (LVO) in stable term and preterm babies using Doppler ultrasound. (bmj.com)
  • Whether reproducibility can be accurately estimated from published information has major implications not only for choosing what to believe or what is worth replicating, but also for how we assess and fund science. (bmj.com)
  • Of course, there might be other ways to assess the probability that these studies are reproducible. (bmj.com)
  • The existence of such data did not alter the efforts of the Reproducibility Project to independently assess the reproducibility of the original studies. (elifesciences.org)
  • Urodynamic studies should assess both the filling and storage phase, as well as the voiding phase of bladder and urethral function. (medscape.com)
  • To assess the reproducibility and validity of the QUEFAC to children aged 7 to 10 years. (bvsalud.org)
  • After the development of instruments that assess food consumption, including the FFQ, it is necessary to evaluate their validity and reproducibility to determine sources of errors inherent to their use. (bvsalud.org)
  • Objective: this study aimed to assess the reproducibility of temporomandibular joint diagnoses using magnetic resonance imaging at 0.5 and 1.5 Tesla. (bvsalud.org)
  • The main cause attributed to the observations described above is a publication and incentive system that rewards the impact and novelty of scientific findings, but does not systematically assess their reproducibility, which is rarely considered in the evaluation of researchers (14,15). (bvsalud.org)
  • The CPSS has excellent reproducibility among prehospital personnel and physicians. (nih.gov)
  • RESULTS: Good to excellent reproducibility (intra-class correlation coefficients = 0.46-0.85) for MDT was found in controls at 22 degrees C. At 18 and 22 degrees C, pre-typing MDT differed between controls and cases by number of symptom sites marked on a hand-arm diagram (ANOVA, P or = 0.05), and by number of UEMSD case definitions met (ANOVA, P or = 0.05). (cdc.gov)
  • Images at 0.5T and 1.5T provided excellent reproducibility for anterior disc displacement without reduction (κ = 0.82 and 0.80, respectively), hypermobility (κ = 0.84 and 0.90), and hypomobility (κ = 0.80 and 0.95), while fair to moderate values were obtained for anterior disc displacement with reduction (κ = 0.48 and 0.42) and disc shape changes (κ = 0.45 and 0.37). (bvsalud.org)
  • Two major steps are naturally distinguished in connection with reproducibility of experimental or observational studies: When new data is obtained in the attempt to achieve it, the term replicability is often used, and the new study is a replication or replicate of the original one. (wikipedia.org)
  • The Brazilian Reproducibility Initiative , which aims to replicate between 60 and a 100 experiments from Brazilian biomedical science using common laboratory methods, provides a unique opportunity to study this question. (bmj.com)
  • Ideally, research results are only worthy of attention, publication, and citation based if independent researchers can replicate them using a particular study's methods and materials. (the-scientist.com)
  • Glenn Begley, former head of research at Amgen and roundtable panel member, spoke of his March revelation that the biotech company's scientists were unable to replicate the results of 47 out of 53 papers that were seminal to launching drug-discovery programs. (the-scientist.com)
  • many scientific studies are difficult or impossible to replicate or reproduce. (speakerdeck.com)
  • should we expect scientific results to always replicate? (speakerdeck.com)
  • Sharing data openly can encourage studies which replicate studies, and allow others to test the validity of your results. (springernature.com)
  • The drug company Bayer could only replicate 20% to 25% of 67 peer-reviewed studies in oncology, women's health, and cardiovascular diseases that were performed between 2007 and 2011. (rationalwiki.org)
  • [7] Another drug company, Amgen, could only replicate 6 out of 53 "landmark" studies in cancer research. (rationalwiki.org)
  • A group of Harvard researchers, led by Daniel Gilbert, claimed that its failure to replicate a given study tended to coincide with divergent methodology from the original. (rationalwiki.org)
  • Of the 67 studies replicated by Bayer, only 21% had been completely reproduced (5), while Amgen could successfully replicate 11% of 53 articles (6). (bvsalud.org)
  • Notably, though, the most famous "failed replication" study supposedly had its own replicability issues. (rationalwiki.org)
  • In this chapter, we will use "reproducibility" and "replicability" interchangeably, indicating that a similar result is obtained when collecting new data under conditions similar to those in the original study. (bvsalud.org)
  • It took until 2023 before the results were published. (lu.se)
  • Despite being as old as MRI itself, most of the qMRI methods have not succeeded to find widespread use in the clinic, at least in part due to a major multicenter reproducibility challenge. (biorxiv.org)
  • T1 relaxometry is a clear example of how availability, transparency and multicenter consistency of pulse sequences influence multicenter reproducibility. (biorxiv.org)
  • Multicenter studies. (who.int)
  • In the patient study, to evaluate the effect on BSI reproducibility, repeated bone scans were prospectively obtained from metastatic prostate cancer patients enrolled in 3 groups (Grp). (snmjournals.org)
  • In the simulation study, to evaluate the effect on BSI accuracy, bone scans of a virtual phantom with predefined skeletal tumor burden (phantom-BSI) were simulated against the range of image counts (0.2, 0.5, 1.0, and 1.5 million) and separately against the resolution settings of the γ-cameras. (snmjournals.org)
  • The primary objective of this study was to evaluate the reproducibility of these heterogeneity measurements. (snmjournals.org)
  • The purpose of this study was to evaluate the validity of CAVI compared with baPWV, the reproducibility of the measurement of CAVI, and the effect of BP changes on CAVI and baPWV. (go.jp)
  • Quality assessment exercises were conducted to evaluate the reproducibility of IS 6110 DNA fingerprinting performed by eight laboratories in the National Tuberculosis Genotyping and Surveillance Network. (cdc.gov)
  • Difficulty in reproducing published biomedical research studies has become a matter of increasing concern that, if unaddressed, will waste limited research funding and may erode public support for research. (nature.com)
  • Another point often related to the lack of reproducibility in biomedical research is the biased use of statistical models. (bvsalud.org)
  • The results of their assessment have been published in the journal Cancer Epidemiology, Biomarkers & Prevention . (who.int)
  • To test the proficiency of laboratories and determine the reproducibility of this genotyping technique in a large network of laboratories, the Centers for Disease Control and Prevention (CDC) instituted quality assessment exercises for the seven genotyping network laboratories. (cdc.gov)
  • If reproducibility variation is dependent, it means that inspector judgment (such as the definition of "finger tight" or how the inspector reads a dial gage) affects the outcome. (complianceonline.com)
  • Boyle, a pioneer of the experimental method, maintained that the foundations of knowledge should be constituted by experimentally produced facts, which can be made believable to a scientific community by their reproducibility. (wikipedia.org)
  • For instance, the differences can be due to the experimental setup, the measurement methods used, the scientific equipment, the calibration of scientific instrumentation or simply due to different samples of the population under study which are seldom directly comparable. (dlib.org)
  • With this in mind, we are recruiting experimental researchers to predict the probability that the results will be replicated - as well as to explain the reasons for their predictions! (bmj.com)
  • Credits can later be redeemed as Amazon gift cards according to prediction success once experimental results are in. (bmj.com)
  • The checklist focuses on experimental and analytical design elements that are critical for the interpretation of research results but that are often reported incompletely. (nature.com)
  • We also continue to encourage authors to use resources for sharing detailed methods and reagent descriptions by providing direct online linking between primary research articles and Protocol Exchange ( http://www.nature.com/protocolexchange/ ), an open resource into which authors can deposit the detailed step-by-step experimental protocols used in their study. (nature.com)
  • The ability to use the same experimental procedures, data, and tools and achieve the same results. (accc-cancer.org)
  • analyse experimental results 4. (ubc.ca)
  • We are able to aggregate data from various sources and correlate experimental results to relevant inputs such as material storage, environmental parameters, time-dependencies, etc. (massbio.org)
  • Reproducibility is a key part of the scientific method and refers to the possibility of reproducing an experimental result by a third party following the same procedures as the original experimenter. (rationalwiki.org)
  • In experimental psychology, several warning signs about the low reproducibility of published findings emerged in the early 2010s (7,8). (bvsalud.org)
  • In recent decades, there has been a rising concern that many published scientific results fail the test of reproducibility, evoking a reproducibility or replication crisis. (wikipedia.org)
  • For the findings of a study to be reproducible means that results obtained by an experiment or an observational study or in a statistical analysis of a data set should be achieved again with a high degree of reliability when the study is replicated. (wikipedia.org)
  • It's not clear why grain-fed mice are better able to recover after infection, but a study's findings suggest food type may skew the results of animal studies. (the-scientist.com)
  • Data were extracted from the included studies, and the findings were presented using a narrative synthesis. (researchgate.net)
  • The question of whether researchers can estimate the reproducibility of published findings has been studied in replication initiatives in psychology (see also this ), economics and social sciences , and the answer is that they are reasonably good at it. (bmj.com)
  • Begley says he cannot publish the names of the studies whose findings are false. (scienceblogs.com)
  • In January 2001, a pilot study comparing the echocardiograms of residents of Vieques and Ponce, Puerto Rico reported substantial valvular abnormalities and pericardial thickening in a large proportion of Vieques residents - findings not seen among Ponce residents. (cdc.gov)
  • In fact, studies have shown that 50% of findings are not reproducible . (massbio.org)
  • Psychology results evaporate upon further review: Surprising reports, findings with marginal statistical significance least likely to be reproduced, study concludes by Bruce Bower (2:00pm, August 27, 2015) Science News . (rationalwiki.org)
  • In recent years, data on the reproducibility of published findings in some areas of research has become available. (bvsalud.org)
  • Thus, the acceptance of an article, particularly in journals that are very selective for high-impact findings, ends up depending not only on the research's methods but also on its results. (bvsalud.org)
  • FINDINGS: Using surveillance results from Dec 14, 2020, to Aug 31, 2021, we identified 21 individuals with MIS-C after COVID-19 vaccination. (cdc.gov)
  • However, its validity and reproducibility must be tested to assert that the instrument has a recognized quality. (bvsalud.org)
  • Only after evaluating the reproducibility and validity of the QUEFAC can the instrument is recognized as a quality tool to be used in the evaluation and monitoring of food consumption changes in longitudinal studies on lifestyle and health at school age. (bvsalud.org)
  • On the reproducibility of extrusion-based bioprinting: round robin study on standardization in the field. (bvsalud.org)
  • Standardization of this technique promises the best results for direct comparison of large numbers of genotype patterns obtained in different laboratories ( 2 - 4 ). (cdc.gov)
  • Factors limiting the usefulness of anergy skin testing include problems with standardization and reproducibility, the low risk for TB associated with a diagnosis of anergy, and the lack of apparent benefit of preventive therapy for groups of anergic HIV-infected persons. (cdc.gov)
  • There are different kinds of replication but typically replication studies involve different researchers using the same methodology. (wikipedia.org)
  • Differences in how researchers prepare and image samples can lead to discrepancies in their results. (the-scientist.com)
  • However, reproducing the "analytical phase" seems less difficult, as it would essentially require access to the primary and/or derived data and to the analytical tools used by the researchers to derive some result. (dlib.org)
  • The pooled prediction accuracy across these four studies is around 66% for individual surveys and 73% for prediction markets, in which a large group of researchers interact in a stock market-like interface to generate predictions. (bmj.com)
  • As a result, researchers choose a microscopy technique that fits their needs. (leica-microsystems.com)
  • The special session also seeks to encourage researchers to exchange their experiences in remote user studies, with non-anonymous test takers, how best practices from crowdsourcing studies can be applied in this context, and discuss which new challenges arise. (wikicfp.com)
  • Our team of expert research data editors do all the time-consuming work of creating high quality metadata records, making your research data understandable and easier to find and use by researchers in your field of study: time that you could use to carry out new research. (springernature.com)
  • The uncertainty and hesitancy of scientists to rely on the end results necessitates a better understanding of the performance and accuracy tradeoff in approximation and ensure methods used for evaluation are reproducible, researchers said. (llnl.gov)
  • The researchers note that although the test performed reliably in this setting and with the quality assurance measures that were in effect during the study, it is important to have robust quality assurance measures in place when determining the feasibility of organized, decentralized cervical cancer screening systems in limited-resource settings. (who.int)
  • Implications for researchers using GYTS include recognition of the survey's data editing methods and documentation in their study methods to ensure cross-study comparability. (cdc.gov)
  • 9 , 10 , 11 Based on the results of the Quality Appraisal of Diagnostic Reliability (QAREL) checklist and Tables 1-3 in the study of Rampes, et al , 2 it could be assumed that the patient populations of the 14 included studies were representative of the population of interest, were stable, and contained some degree of heterogeneity. (jrheum.org)
  • Nonetheless, systematic manipulation of effective micrometer-level MRI parameters via specialized acquisition methods, followed by fitting the resulting data to a signal representation or a biophysical model 3 , can yield parametric maps, turning scanners into quantitative diagnostic tools. (biorxiv.org)
  • Methodological study with quantitative approach of cross-cultural adaptation (translation, back-translation, synthesis, expert committee, and pretest) and validation with 497 employees from 72 teams of the Family Health Strategy in the city of Campinas, SP, Southeastern Brazil. (scielo.br)
  • Unfortunately, too many biologists still do not receive adequate training in statistics and other quantitative aspects of their area of study, and mentoring of young scientists on matters of rigor and transparency is inconsistent at best. (nature.com)
  • New reporting standards for Nature journal authors are intended to improve transparency and reproducibility. (nature.com)
  • Ensuring systematic attention to reporting and transparency is only a small step toward solving the issues of reproducibility that have been highlighted across the life sciences. (nature.com)
  • Newly instituted by the conference, the award recognizes outstanding efforts in advancing transparency and reproducibility of methods for high performance computing (HPC). (llnl.gov)
  • It speaks to the importance that SC gives to reproducibility and transparency in reproducing results. (llnl.gov)
  • The ability to draw similar conclusions through replicating or reanalyzing a study or test. (accc-cancer.org)
  • Several regional heterogeneity parameters such as variability in the intensity and size of regions of homogeneous activity distribution had reproducibility similar to that of SUV measurements, with 95% confidence intervals of −22.5% to 3.1% and −1.1% to 23.5%, respectively. (snmjournals.org)
  • Several parameters derived from textural analysis describing heterogeneity of tracer uptake by tumors on local and regional scales had reproducibility similar to or better than that of simple SUV measurements. (snmjournals.org)
  • Until now, only a few studies have investigated the physiologic reproducibility of such measurements, almost exclusively focusing on SUVs ( 9 - 11 ) and more recently on MATV computed using different segmentation algorithms ( 12 , 13 ). (snmjournals.org)
  • Simple urodynamic tests involve performing noninvasive uroflow studies, obtaining a postvoid residual (PVR) urine measurements, and performing single-channel cystometrography (CMG). (medscape.com)
  • Quantitation of p53 immunohistochemistry (IHC) by CAS was very reproducible by the same observer (r = .99), but its interobserver reproducibility was lower, and the measurement was time consuming (r = .81, 35 minutes). (nih.gov)
  • 9 , 10 , 11 Further, reliability parameters are highly dependent on the heterogeneity of the study sample, since reliability can also be explained as the ability of a measurement to distinguish between patients. (jrheum.org)
  • In this study, we wanted to establish normal values of flow volume measurement from the right CCA in stable preterm and term infants. (bmj.com)
  • This study aims to describe how to measure the sacropelvic parameters necessary for S2AI screw insertion and to validate this measurement technique. (usp.br)
  • The measurement of CAVI demonstrated good reproducibility and was not affected by the increase in BP during measurement. (go.jp)
  • The first aim of this study is to investigate the within and between-day reliability of the most frequently used formulas to calculate the rate of displacement. (plos.org)
  • TRACKMAN® Connected is a tablet with accessories and apps that makes pipetting faster and more verifiable, which improves reliability, traceability, and reproducibility at the bench. (the-scientist.com)
  • Rampes, et al 2 used the term reproducibility , which is part of the domain of reliability. (jrheum.org)
  • Replications will occur within a countrywide network along the course of 2020, with results due in mid-2021. (bmj.com)
  • In fact, meta-studies in psychology, medicine and also computer science have documented the challenges involved therein and they have empirically shown that the success rate in reproduction of research results is low. (dlib.org)
  • A low success rate in reproducibility has been particularly observed in psychology. (dlib.org)
  • Awareness of reproducibility issues in various areas of science has been on the rise in recent years, with systematic replication efforts in areas such as psychology , economics , cancer biology and social sciences arising in recent years. (bmj.com)
  • It was even demonstrated that laypeople without a PhD in psychology show some accuracy in predicting reproducibility in these studies. (bmj.com)
  • These include indicators of methodological rigor such as randomisation and blinding, which are widely thought to reduce risk of bias , as well as effect sizes and statistical results - which have been shown to correlate with reproducibility in psychology studies . (bmj.com)
  • [4] A large-scale replication project was published in 2015 of the results of replication attempts of original published psychology experiments from 2008. (rationalwiki.org)
  • In 2015, the results of a large systematic replication of studies in cognitive and social psychology were released, which indicated success rates between 36% and 47% (9). (bvsalud.org)
  • Multichannel urodynamic studies are more complex than simple urodynamics and can be used to obtain additional information, including a noninvasive uroflow, PVR, filling CMG, abdominal leak-point pressure (ALPP), voiding CMG (pressure-flow study), and electromyography (EMG). (medscape.com)
  • Only after one or several such successful replications should a result be recognized as scientific knowledge. (wikipedia.org)
  • The air pump, which in the 17th century was a complicated and expensive apparatus to build, also led to one of the first documented disputes over the reproducibility of a particular scientific phenomenon. (wikipedia.org)
  • Such assertions express a common dogma in modern science that reproducibility is a necessary condition (although not necessarily sufficient) for establishing a scientific fact, and in practice for establishing scientific authority in any field of knowledge. (wikipedia.org)
  • Analytical reproducibility in scientific research has become a keenly discussed topic within scientific research organizations and acknowledged as an important and fundamental goal to strive for. (dlib.org)
  • Recently published scientific studies have found that irreproducibility is widely prevalent within the research community, even after releasing data openly. (dlib.org)
  • Reproducibility of scientific research is an essential principle within science. (dlib.org)
  • Scientific results should stand the scrutiny of the research community and should be verifiable by peers. (dlib.org)
  • Failure to reproduce scientific results can have many causes. (dlib.org)
  • An important step in the generation of scientific results lies in the computational analysis of the primary data or derived secondary data. (dlib.org)
  • A recent roundtable discussion identifies challenges facing the scientific community regarding a lack of reproducible results in the literature. (the-scientist.com)
  • But for much of the scientific literature, results aren't reproducible at all. (the-scientist.com)
  • Quackery supporters of all stripes are jumping on the bandwagon to imply that this study somehow "proves" that the scientific basis of medicine is invalid. (scienceblogs.com)
  • The scientific study of the form and structure of cells or organisms. (accc-cancer.org)
  • So why are results from scientific experiments so difficult to reproduce? (massbio.org)
  • The 2021 International Conference for High Performance Computing, Networking, Storage and Analysis (SC21) on Nov. 18 presented the inaugural Best Reproducibility Advancement Award to a Lawrence Livermore National Laboratory team for a benchmark suite aimed at simplifying the evaluation process of approximation techniques for scientific applications. (llnl.gov)
  • A suite developed by a Lawrence Livermore National Laboratory (LLNL) team to simplify evaluation of approximation techniques for scientific applications has won the first-ever Best Reproducibility Advancement Award at the 2021 International Conference for High Performance Computing, Networking, Storage and Analysis (SC21). (llnl.gov)
  • We're quite honored to be receiving the very first SC Best Reproducibility Advancement Award," said principal investigator Harshitha Menon, a computer scientist in LLNL's Center for Applied Scientific Computing. (llnl.gov)
  • While approximate computing - techniques that produce results that are "almost correct" - can substantially improve performance, adoption has been limited for scientific applications due to strict accuracy requirements, Menon explained. (llnl.gov)
  • Scientific experiments can also lack reproducibility, [2] but this just indicates either that the original experiment was flawed, that a better understanding of the problem is needed, or it is something that for its nature happens very often. (rationalwiki.org)
  • The process of verification and correction of published science, however, occurs in a non systematic way, which means that reproducibility is not guaranteed by scientific publication in its current format. (bvsalud.org)
  • It should be noted that the reproducibility of a scientific finding can be defined in many ways, and that there is no consensus on the use of the terms "reproducible" and "replicable" (1,2). (bvsalud.org)
  • This leads to a literature that is full of positive and impacting results, but usually at the expense of selective or biased analyses and inflated effects, which distort our perception of the scientific problems under study (16). (bvsalud.org)
  • OBJECTIVE: This study aimed to examine the suitability of using mean dorsal (hand) skin temperature (MDT) before and after a short typing task as an indicator of upper extremity musculoskeletal disorder (UEMSD) severity. (cdc.gov)
  • Our primary result is that the post-dive decrease in PC could be a predictor of decompression severity after diving. (who.int)
  • Reproducibility was measured as the absolute difference between the repeated BSI values, and accuracy was measured as the absolute difference between the observed BSI and the phantom-BSI values. (snmjournals.org)
  • No significant difference was observed in the accuracy data of the simulation study with vendor-specific γ-cameras ( P = 0.266). (snmjournals.org)
  • In this study, we observed that the automated BSI accuracy and reproducibility were dependent on scanning speed but not on the vendor-specific γ-cameras. (snmjournals.org)
  • The end results are accuracy, reproducibility, and optimization. (massbio.org)
  • All relevant data from this study will be made available upon study completion. (plos.org)
  • With a narrower scope, reproducibility has been introduced in computational sciences: Any results should be documented by making all data and code available in such a way that the computations can be executed again with identical results. (wikipedia.org)
  • Obtaining the same results when analyzing the data set of the original study again with the same procedures, many authors use the term reproducibility in a narrow, technical sense coming from its use in computational research. (wikipedia.org)
  • An electronic laboratory notebook (ELN) keeps data organized and secure, boosting productivity and reproducibility. (the-scientist.com)
  • Thus, it appears feasible to strive for a more reduced version of reproducibility that we will refer to as "analytical reproducibility" in order to ensure that a third party researcher could reproduce the computational/statistical analysis performed on derived data to yield a particular conclusion, thereby being able to independently verify the results and research hypothesis. (dlib.org)
  • However, the mere availability of data is not enough to ensure analytical reproducibility. (dlib.org)
  • Common issues include variability in material storage, poor study design, and data analysis issues. (massbio.org)
  • In this review, we discuss considerations of the study design for each data feature, the limitations in gene and protein abundance and their rate of expression, the current data integration methods, and microbiome influences on gene and protein expression. (rsc.org)
  • There is currently a growing concern to conduct health-related quality of life (HRQOL) studies among people with epilepsy in low- and middle-income countries, as most data have been derived from high-income countries in North America and Europe. (who.int)
  • Information from NHANES III pulmonary studies will be used to provide reference data for occupational exposure research, air quality studies, and specialized cardiovascular research, as well as documentation of the relationship of smoking to COPD. (cdc.gov)
  • However, some sources propose different uses of the two terms to distinguish the reproducibility of analyses based on the same data from those based on new experiments or observations (3). (bvsalud.org)
  • These tests, however, are usually applied flexibly after data collection and examination, and end up being reported selectively according to the results found (18,19). (bvsalud.org)
  • Compared with GYTS data edits, the do-nothing and gatekeeper approaches produced similar estimates, whereas the global approach resulted in lower estimates and the preponderance approach, higher estimates. (cdc.gov)
  • Results: - study of the behaviour of complex algorithms - study of properties / behaviour of complex software / hardware components / systems - study of interactions between systems and their users - study of hardness of certain computational problems - development and study of engineering principles (algorithms, software, hardware) - others? (ubc.ca)
  • The result is a "computational mirror. (zdnet.com)
  • Complete reproducibility of an experiment can be extremely difficult. (dlib.org)
  • Postgraduates from around the world choose the opportunity to become part of our interdisciplinary international PhD community and conduct their doctoral studies at the Biozentrum - one of the world-leading institutes in the Life Sciences. (unibas.ch)
  • Participants will be initially asked to make predictions on the reproducibility of 20 experiments in a survey. (bmj.com)
  • Once they complete the survey, they will enter the markets, in which they will receive credit to bet on the results of individual experiments in a stock market-like environment along with other participants. (bmj.com)
  • The results of the experiments are then published as a Replication Study, irrespective of the outcome, but subject to peer review to check that the designs and protocols contained in the Registered Report were followed. (elifesciences.org)
  • It is important to note that only selected experiments (or figures) from the original paper would be repeated, and in some cases these did not include key experiments in the original studies. (elifesciences.org)
  • The experiments in the Reproducibility Project are typically powered to have an 80% probability of reproducing something that is true: this means that if we attempt to repeat three experiments from a paper, there is only a ~50% chance that all three experiments will yield significant p values, even if the original study was reproducible. (elifesciences.org)
  • If a replication reproduces some of the key experiments in the original study, and sees effects that are similar to those seen in the original in other experiments, we need to conclude that it has substantially reproduced the original study. (elifesciences.org)
  • Areas of concern that emerged during the peer review process included the limited budget for in vivo experiments and, in some cases, the possibility that the scope of the proposed experiments might not be sufficient to adequately explore the reproducibility of the original studies. (elifesciences.org)
  • One of the signs of pseudoscience is a lack of reproducibility in their experiments. (rationalwiki.org)
  • In contrast, academic journals are interested in novel experiments with significant results. (rationalwiki.org)
  • It provides an instrument that allows the evaluation of teams to monitor the effectiveness of teamwork in producing results in the care of users and population. (scielo.br)
  • According to a study performed in Casablanca in 1998, 1.1% of the population was affected by epilepsy. (who.int)
  • In Brazil, the study by Scagliusi et al.6 developed an FFQ for a population of school children from the Brazilian West Amazon, and the study by Matos et al . (bvsalud.org)
  • In this context, the special session aims to foster contributions following the traditional way of optimizing and designing crowdsourced subjective studies for Quality of Experience and User Experience research and additionally wants to raise awareness and foster research in a new research direction, the Quality of Experience and User Experience of crowdsourcing workers. (wikicfp.com)
  • This study evaluated the analytical and clinical performance of these kits. (frontiersin.org)
  • Results: Of the 120 papers identified, only 14 were related to systematic reviews. (researchgate.net)
  • Properties of artifacts in computing are usually studied by means of theoretical analysis and/or (more or less) systematic testing. (ubc.ca)
  • By comparison, better reproducibility was measured for some textural features describing local heterogeneity of tracer uptake, such as entropy and homogeneity, with a mean percentage difference of −2% ± 5.4% and 1.8% ± 11.5%, respectively. (snmjournals.org)
  • Recent multi-omics studies have revealed the heterogeneity and complexity of tumor features such as their genetic mutations, transcriptome, proteins, and signaling pathways. (rsc.org)
  • 5 , 6 The review is a timely topic of relevance to patients, clinical practice, and research, but some limitations specific to this study were identified. (jrheum.org)
  • At Bielefeld University, nine research project groups from varied disciplines have embarked on a "reproducibility" journey by collaborating on the Conquaire project as case study partners. (dlib.org)
  • In practice, however, reproducing or confirming previous research results can be a major challenge. (dlib.org)
  • This would be a significant step, in our view, towards supporting reproducibility in research. (dlib.org)
  • Reproducibility is a cornerstone of science, and the development of new drugs and medical treatments relies on the results of preclinical research being reproducible. (elifesciences.org)
  • The aim of the Reproducibility Project: Cancer Biology, which is a collaboration between the Center for Open Science and Science Exchange, is two-fold: to provide evidence about reproducibility in preclinical cancer research, and to identify the factors that influence reproducibility more generally. (elifesciences.org)
  • The ORI Division of Education and Integrity (DEI) has released a new series of video case studies to address integrity issues faced by those involved in the research endeavor. (hhs.gov)
  • Laboratory studies are an established and essential tool for Quality of Experience (QoE) and User Experience (UX) research. (wikicfp.com)
  • This report was prepared by Eastern Research Group, Inc. (ERG), a contractor to the Agency for Toxic Substances and Disease Registry (ATSDR), as a general record of discussion for the expert panel review meeting on the Vieques Heart Study. (cdc.gov)
  • We will all be using a checklist ( http://www.nature.com/authors/policies/checklist.pdf ) intended to prompt authors to disclose technical and statistical information in their submissions and to encourage referees to consider aspects important for research reproducibility. (nature.com)
  • But most research studies can be robustly assessed with existing statistical methods, when they are applied properly. (nature.com)
  • This research often requires the tissue-specific expression of transgenes to better mirror human diseases, to visualize pathways being studied or to modulate the expression of a disease-related gene. (nature.com)
  • Simulations show that for most study designs and settings, it is more likely for a research claim to be false than true. (speakerdeck.com)
  • Scientists from the International Agency for Research on Cancer (IARC) and partner institutions assessed the intra-laboratory and inter-observer reproducibility of a rapid test for detection of high-risk human papillomavirus (HPV) types at three different levels of the health-care system in one urban region and one rural region in the United Republic of Tanzania. (who.int)
  • There are major reproducibility problems in research. (lu.se)
  • Research suggests that editing procedures have potential effects on point estimates and cross-study comparability (3-5). (cdc.gov)
  • Objective The aim of this study was to compare the number of antihypertensive drugs used by older female adults (aged ≥ 60 years) with a low level of physical activity with the number used by those with a high level of physical activity, and to verify how many participants used more than two antihypertensive drugs. (researchgate.net)
  • In the past months, the pandemic situation made it even more challenging to conduct laboratory studies by increasing the organizational overhead and limiting potential participants. (wikicfp.com)
  • Langen G, Lohr C, Ueberschär O, Behringer M (2022) Reproducibility of knee extensor and flexor contraction velocity in healthy men and women assessed using tensiomyography: A study protocol. (plos.org)
  • Methods: The Cochrane Library, CENTRAL, MEDLINE, LILACS, EMBASE, and CRD databases were searched based on the eligibility criteria for all types of studies on NIV use in patients with ALS published up to January 2022. (researchgate.net)
  • The theoretical framework on which null-hypothesis significance tests are based presupposes an a priori definition of the variables under study and of the hypotheses tested. (bvsalud.org)
  • For reproducibility, mean differences were observed for all nutrients investigated, correlation coefficients ranged from 0.12 to 0.54 and Kappa values from 0.01 to 0.39. (bvsalud.org)
  • As underscored in three Correspondences in this issue, statistical analysis of reproducibility itself is still immature. (nature.com)
  • Overall, this test series demonstrated repeatable and reproducible results for the OMDB, vehicle, and driver occupant in the oblique offset test procedure. (sae.org)
  • This study sought to overcome methodological problems (e.g., sampling frame, lack of blinding) in the earlier pilot study. (cdc.gov)
  • Inspiration was also taken from published studies and guidelines about reporting standards (or the lack thereof) and by the collective experience of editors at Nature journals. (nature.com)
  • To test the reproducibility and time effectiveness of two immunoquantitation and sampling methods in Barrett's esophagus (BE) mucosa. (nih.gov)
  • This study has also identified a few areas where the test procedure can be refined, including improved vehicle sensor mounting requirements and dummy seating procedure. (sae.org)
  • Discrepancy between any two or more test results for a single sample. (accc-cancer.org)
  • Log into MyQuest ® to book or reschedule a lab visit, view test results, and more. (questdiagnostics.com)
  • The objective of this study was to validate and verify the reproducibility of the CPSS when used by prehospital providers. (nih.gov)
  • Studies that do not reproduce the patient's symptoms are inconclusive. (medscape.com)
  • Of course, reproducibility alone is not enough when even random numbers can reproduce prior results. (rationalwiki.org)
  • The White House asked the Department of Health and Human Services to investigate the issues raised by the study. (cdc.gov)
  • This application note details a metrology solution that addresses these issues and provides manufacturers a way to measure lead angle both quantitatively and repeatably with complete confidence in the results. (ai-online.com)
  • The first to stress the importance of reproducibility in science was the Irish chemist Robert Boyle, in England in the 17th century. (wikipedia.org)
  • Most striking of all was the study of 21 social sciences articles in Science and Nature , in which the market ranked all of the 14 replicated studies ahead of the 7 non-replicated ones (if you want to try your hand at it, there's an online quiz available . (bmj.com)
  • Die Chemiker (detail), Ernst Karl Georg Zimmermann (1852-1901) WIKIMEDIA, DOROTHEUM The gold standard for science is reproducibility. (the-scientist.com)
  • Later on, Vox doubled down on his misunderstanding by trying to argue that the study he so eagerly gloated over proves that science is not, in fact, "self-correcting. (scienceblogs.com)
  • Estimating the reproducibility of psychological science by B. A. Nosek et al. (rationalwiki.org)
  • Response to Comment on "Estimating the reproducibility of psychological science" , Anderson et al. (rationalwiki.org)
  • The causes and remedies for this state of affairs was the topic of a recent panel discussion titled "Sense and Reproducibility," held at the annual meeting of the American Society for Cell Biology in San Francisco, California. (the-scientist.com)
  • In a tissue, brightfield microscopy or basic widefield fluorescence microscopy can be sufficient for viral studies. (leica-microsystems.com)