• It is the second most common type of kidney cancer, but accounts for only five to 10 percent of all primary renal malignant tumors. (wikipedia.org)
  • If ovarian cancer spreads, cancerous tumors most often appear in the abdominal cavity or on the surfaces of nearby organs such as the bladder or colon. (medlineplus.gov)
  • Tumors that begin at one site and then spread to other areas of the body are called metastatic cancers. (medlineplus.gov)
  • The biological role and underlying mechanism of action of zinc-finger protein 326 (ZNF326) in malignant tumors, including breast cancer, are still not clear. (cancerindex.org)
  • We analyzed 223 patients (25 with preinvasive tumors and 198 with invasive and metastatic breast cancers) and 153 noncancer controls. (aacrjournals.org)
  • These lesions are accessible through endoscopic/endobronchial ultrasound-guided or computed tomography-guided fine-needle aspiration cytology and represent a wide range of primary and metastatic tumors. (allenpress.com)
  • Tumors metastatic to mediastinal lymph nodes represent the most common mediastinal lesions and must be differentiated from primary lesions. (allenpress.com)
  • Divergent, yet interconnected and overlapping, molecular pathways are likely responsible for the development of noninvasive and invasive bladder tumors. (healthybladderclub.com)
  • Loss of heterozygosity on chromosome 9 is among the most frequent genetic alterations in bladder tumors and is considered an early event. (healthybladderclub.com)
  • Pheochromocytomas and catecholamine-secreting paragangliomas have a similar clinical presentation, but the risk for associated neoplasms, risk for malignancy, and genetic testing is different between the tumors. (medscape.com)
  • Tumors have also been found in the neck, mediastinum, urinary bladder, and virtually every other site. (medscape.com)
  • Resolving the Pathogenesis of Anaplastic Wilms Tumors through Spatial Mapping of Cancer Cell Evolution. (lu.se)
  • Overall for PPGLs, patients with metastatic disease are younger than ones with non-metastasizing tumors at the time of diagnosis. (encyclopedia.pub)
  • The incidence of adrenocortical tumors in children is extremely low (only 0.2% of pediatric cancers). (oncolink.org)
  • In the non-Brazilian cases, relatives of children with adrenocortical tumors often, although not invariably, have a high incidence of nonadrenal cancers (Li-Fraumeni syndrome). (oncolink.org)
  • These cancers are described as hereditary and are associated with inherited gene mutations. (medlineplus.gov)
  • Cancers occur when a buildup of mutations in critical genes-those that control cell growth and division or repair damaged DNA-allow cells to grow and divide uncontrollably to form a tumor. (medlineplus.gov)
  • These changes, which are called somatic mutations, are not inherited. (medlineplus.gov)
  • Somatic mutations in the TP53 gene occur in almost half of all ovarian cancers. (medlineplus.gov)
  • Somatic mutations in many other genes have also been found in ovarian cancer cells. (medlineplus.gov)
  • Another germline deletion ( TGFBR1*6A ) and somatic mutations in the TGFBR1 were also analyzed by PCR and single-strand conformational polymorphism. (aacrjournals.org)
  • Key tumor suppressor genes inactivated by "greater promoter" methylation and somatic mutations in head and neck cancer. (uchicago.edu)
  • Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas. (uchicago.edu)
  • Somatic mutations in fibroblast growth receptor3 and tumor protein p53 in tumor cells appear to be important early molecular events in the noninvasive and invasive pathways, respectively. (healthybladderclub.com)
  • These preliminary results paved the way for a vast number of studies on the role of cellular protein p53 in the cancer biology field, leading to the discovery that p53 mutations are the most common genetic alteration in human cancers. (encyclopedia.pub)
  • Dacomitinib is an irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor indicated for the treatment of patients with advanced non-small cell lung cancer (NSCLC) and EGFR-activating mutations. (preprints.org)
  • Diagnosis includes urine analysis and imaging of the urinary tract (cystoscopy). (wikipedia.org)
  • Some particular examples are listed below: Certain drugs, such as cyclophosphamide, via the metabolites acrolein and phenacetin, may predispose to the development of transitional cell carcinomas (the latter especially with respect to the upper urinary tract). (wikipedia.org)
  • TCC can arise anywhere in the urinary tract, including the renal pelvis, ureter, bladder, and urethra, but it is usually found in the urinary bladder. (medscape.com)
  • the expression level of ZNF326 was inversely associated with advanced pTNM stage (P = 0.002), positive lymph node metastasis (P = 0.004), poor prognosis in patients with breast cancer (P = 0.0097), and ER/PR/Her2 status (P = 0.013). (cancerindex.org)
  • Transitional cell carcinoma, also called urothelial carcinoma, is a type of cancer that typically occurs in the urinary system. (wikipedia.org)
  • Symptoms of urothelial carcinoma in the bladder include hematuria (blood in the urine). (wikipedia.org)
  • When the term "urothelial" is used, it specifically refers to a carcinoma of the urothelium, meaning a transitional cell carcinomas of the urinary system. (wikipedia.org)
  • The 1973 WHO grading system for transitional cell carcinomas (papilloma, G1, G2 or G3) is most commonly used despite being superseded by the 2004 WHO grading for papillary types (papillary neoplasm of low malignant potential [PNLMP], low grade, and high grade papillary carcinoma). (wikipedia.org)
  • H&E stain Papillary transitional cell carcinoma, low grade Histopathology of urothelial carcinoma of the urinary bladder, showing a nested pattern of invasion. (wikipedia.org)
  • Cross-section through the bladder, uterus, and vagina with squamous cell carcinoma of the bladder infiltrating through the bladder wall into the vaginal wall. (medscape.com)
  • The treatment of non-muscle-invasive bladder cancer (Ta, T1, carcinoma in situ [CIS]) begins with transurethral resection of bladder tumor (TURBT). (medscape.com)
  • Inhibitors of programmed cell death 1 (PD-1) protein and its ligands PD-L1 and PD-L2, are first-line agents in patients with metastatic urothelial carcinoma who are not candidates for platinum-containing chemotherapy, and second-line agents for those with disease progression despite cisplatin-based chemotherapy. (medscape.com)
  • The group has described the genomic landscape of head & neck squamous cell carcinoma, esophageal cancer and medullary thyroid cancer, and has developed assays using tumor DNA as a biomarker in saliva and plasma. (uchicago.edu)
  • The Impact of Tonsillectomy upon the Risk of Oropharyngeal Carcinoma Diagnosis and Prognosis in the Danish Cancer Registry. (uchicago.edu)
  • Squamous cell carcinoma (SCC) is the second most common cell type associated with bladder cancer in industrialized countries. (medscape.com)
  • Epithelial carcinoma makes up 85% to 90% of ovarian/fallopian tube cancers. (cancer.net)
  • Impact of Squamous Histology on Clinical Outcomes and Molecular Profiling in Metastatic Urothelial Carcinoma PatientsTreated With Immune Checkpoint Inhibitors or Enfortumab Vedotin. (ucsf.edu)
  • Factors associated with survival in pediatric adrenocortical carcinoma: An analysis of the National Cancer Data Base (NCDB). (oncolink.org)
  • Radiation exposure Somatic mutation, such as deletion of chromosome 9q, 9p, 11p, 17p, 13q, 14q and overexpression of RAS (oncogene) and epidermal growth factor receptor (EGFR). (wikipedia.org)
  • The TGFBR1*6A allele was not significantly associated with breast cancer patients and only one somatic mutation was found in 71 breast cancers. (aacrjournals.org)
  • The classic organ systems are influenced by ters DNA repair or causes genomic mutation theory of cancer no longer mechanistic events associated with instability, (4) induces epigenetic fully encompasses the mechanistic cancer induction. (who.int)
  • In the Brazilian cases, the patients' families do not exhibit a high incidence of cancer, and a single, unique mutation at codon 337 in exon 10 of the TP53 gene is consistently observed. (oncolink.org)
  • CONTEXT: We present an overview of the updated 2023 European Association of Urology (EAU) guidelines for muscle-invasive and metastatic bladder cancer (MMIBC). (bvsalud.org)
  • Advanced bladder cancer These are bladder cancers which are pT4 which indicates that it has grownthrough the bladder wall or have spread to nearby lymph nodes to varying degrees- referred to as N1, N2 or N3) or to other sites in the body referred to as M1. (healthyskinworld.com)
  • When prostate cancer metastasizes or spreads, it commonly spreads by lymphatic vessels or by the bloodstream and most commonly, they tend to go to either lymph nodes or bones or some combination of both. (powerfulpatients.org)
  • According to the authors, "in cases in which the MCED test detects a cancer signal in this context, the probability of a diagnosis of cancer being made is considerably higher and may identify cancers at sites other than those suspected during the initial referral phase, thus reducing delays in diagnosis. (medscape.com)
  • Diagnosis can be made based on elevated levels of urinary catecholamines, but localization may require various modalities (see the images below, as well as Workup). (medscape.com)
  • It's not common that treatment for most health problems, including most cancers, needs to start immediately after diagnosis. (surgerysecondopinion.com)
  • Many oncology treatments are now calling on immunotherapy approaches, and scores of studies have investigated the role of p53 antibodies in cancer diagnosis and therapy. (encyclopedia.pub)
  • Metastatic cases are characterized by a 10-year earlier age of diagnosis. (encyclopedia.pub)
  • Progress in advanced prostate cancer has led to more personalized treatment options and individualized care for people with this diagnosis. (powerfulpatients.org)
  • Unfortunately, not all are curable and some will recur despite these curative intent treatments and others might just be inherently more aggressive biologically and they could even present with metastatic disease or stage IV disease having spread to other sites outside of the prostate gland, even at diagnosis. (powerfulpatients.org)
  • Yang et al (200examined 454 Formosan subjects hospitalized with sepsis buy discount danazol 200mg on-line breast cancer diagnosis. (fosite.ru)
  • Low risk non-muscle invasive bladder cancer These are small , single low grade Grade 1 or Grade 2) bladdercancers that haven't grown beyond the inner layer of the bladder. (healthyskinworld.com)
  • Intermediate risk non-muscle invasive bladder cancer These are larger or multiple low grade pTa bladder cancers.Small, single low grade pT1 tumours are also in this category where T1indicates that the cancer has grown a little further into the bladder wall. (healthyskinworld.com)
  • High risk non-muscle invasive bladder cancer These are Grade 3 pTa or pT1 bladder cancers. (healthyskinworld.com)
  • Muscle invasive bladder cancer These are bladder cancers which are pT2 or pT3 which indicates that the cancerhas grown further into the bladder wall and is found in the inner muscle layer. (healthyskinworld.com)
  • Urodrill - a novel MRI-guided endoscopic biopsy technique to sample and molecularly classify muscle-invasive bladder cancer without fractionating the specimen during transurethral resection. (lu.se)
  • As with most epithelial cancers, physical irritation has been associated with increased risk of malignant transformation of the urothelium. (wikipedia.org)
  • Almost all bladder cancers originate in the urothelium, which is a 3- to 7-cell mucosal layer within the muscular bladder. (medscape.com)
  • Functional improvement in spinal cord injury-induced neurogenic bladder by bladder augmentation using bladder acellular matrix graft in the rat. (ucsf.edu)
  • and neurogenic bladder and the overuse of indwelling catheters. (healthybladderclub.com)
  • It is the most common type of bladder cancer and cancer of the ureter, urethra, and urachus. (wikipedia.org)
  • The uterus is located in the pelvis, between the bladder and rectum, and the vagina is located behind the urethra, which connects to the bladder. (cancer.net)
  • A woman's lifetime risk of developing ovarian cancer is about 1 in 75. (medlineplus.gov)
  • Liquid biopsies based on genomic biomarkers could make MCED a reality, especially for cancers for which there is no standard screening process. (medscape.com)
  • This study aimed to explore the genomic and transcriptomic landscape of bladder cancer (BC) and its implication for treatment with an immune checkpoint inhibitor (ICI). (e-crt.org)
  • In this form of cancer, certain cells in the ovary become abnormal and multiply uncontrollably to form a tumor . (medlineplus.gov)
  • The term "ovarian cancer" is often used to describe cancers that begin in the cells in the ovary, fallopian tube, or peritoneum. (cancer.net)
  • It accounts for 95% of bladder cancer cases and bladder cancer is in the top 10 most common malignancy disease in the world and is associated with approximately 200,000 deaths per year in the US. (wikipedia.org)
  • Bladder cancer is a common urologic cancer that has the highest recurrence rate of any malignancy. (medscape.com)
  • Breast cancer is the most common form of malignancy among women in the United States with 211,240 new cases and 40,410 deaths from the disease anticipated in 2005 ( 1 ). (aacrjournals.org)
  • In hereditary ovarian cancer, the associated genetic changes are passed down within a family. (medlineplus.gov)
  • However, much of the genetic contribution to breast cancer risk remains unknown. (cancerindex.org)
  • Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA. (uchicago.edu)
  • DBC1 promotes castration-resistant prostate cancer by positively regulating DNA binding and stability of AR-V7. (cancerindex.org)
  • Constitutively active AR-V7, one of the major androgen receptor (AR) splice variants lacking the ligand-binding domain, plays a key role in the development of castration-resistant prostate cancer (CRPC) and anti-androgen resistance. (cancerindex.org)
  • Methods: An ESTRO ACROP contouring consensus panel consisting of 12 radiation oncologists and one radiologist, all with subspecialty expertise in prostate cancer, was established. (bvsalud.org)
  • The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs Part B: Prostate and Bladder Tumours P A Humphrey and othersEuropean Urology, 2016. (healthyskinworld.com)
  • doi:10.7287/peerj.9626v0.1/reviews/1, Soković, M., Glamoclija, J., and Ciric, A. Thymol also caused a decrease in cell viability of prostate cancer (PC-3 cell line), and provoked cytotoxic effects (Pathania et al. (dieselok.md)
  • Today's program focuses on how people with advanced prostate cancer can access the best treatment in care. (powerfulpatients.org)
  • I focus on prostate cancer and other cancers involving the urinary system. (powerfulpatients.org)
  • Dr. Gao, this program is focusing on advanced prostate cancer. (powerfulpatients.org)
  • I think advanced prostate cancer can mean a lot of different things, but in general, it means a prostate cancer that has either spread out from the prostate gland itself to other areas of the body or has recurred despite either surgery or radiation-based therapy to the primary prostate tumor. (powerfulpatients.org)
  • In each of these situations, typically the focus would on medication types of treatments and we think about advanced prostate cancer as either hormone-sensitive or hormone-resistant, or the other term in the field for it would be castration-resistant, meaning that the prostate cancer is either sensitive to hormonal therapies or perhaps it's no longer sensitive to the most common type of hormone therapy called androgen deprivation therapy. (powerfulpatients.org)
  • So, those are sort of the ways that the cancer can progress, and typically all these cancers start as hormone-sensitive prostate cancers and over time, they may evolve and become resistant and become what we call castration-resistant prostate cancer. (powerfulpatients.org)
  • All advanced prostate cancers are by definition stage IV. (powerfulpatients.org)
  • All advanced cancers, in general, are stage IV but advanced prostate cancer would be stage IV. (powerfulpatients.org)
  • Most prostate cancers actually present as localized prostate cancer, stage I, stage II, even stage III prostate cancers and the majority of localized prostate cancers are actually fortunately quite curable with either surgery or radiation-based therapies. (powerfulpatients.org)
  • APOBEC Mutational Signature and Tumor Mutational Burden as Predictors of Clinical Outcomes and Treatment Response in Patients With Advanced Urothelial Cancer. (ucsf.edu)
  • I'm also involved in our clinical trials program where we're studying newer and what we hope are better treatments for these types of cancers. (powerfulpatients.org)
  • We hypothesize that this germline variant may be involved in development and progression of breast cancer. (aacrjournals.org)
  • These data suggest that the germline Int7G24A variant may represent a risk factor for invasive breast cancer and a marker for breast cancer progression. (aacrjournals.org)
  • Alternatively, a bladder-sparing approach of TURBT followed by concurrent radiation therapy and systemic chemotherapy (trimodality therapy) may be used. (medscape.com)
  • Chemotherapy and radiotherapy have been used in metastatic and unresectable pheochromocytoma, but their value is questionable. (medscape.com)
  • Urothelial bladder cancer (BC) represents a highly heterogeneous disease with regard to natural history, ranging from non-muscle invasive BC (NMIBC), which represents 75% of primary diagnoses and is characterized by frequent recurrence but a low risk of mortality, to muscle invasive BC (MIBC), which requires platinum-based chemotherapy followed by radical surgery, to metastatic disease [ 1 ]. (e-crt.org)
  • The introduction and refnement of cisplatin-primarily based mixture chemotherapy revolutionized the remedy Keywords of testicular cancer pain treatment alternative buy cheap cafergot . (metjesmartphonehetbosin.nl)
  • Is 6 Months the Optimal Duration of Adjuvant Chemotherapy for Pancreatic Cancer? (cancerdiagnosisprognosis.org)
  • Colton MD, Tompkins K, O'Donnell E, Aisner D, Lieu CH, Konnick EQ, Fishbein L. Case of Metastatic Pheochromocytoma and Meningiomas in a Patient With Lynch Syndrome. (ucdenver.edu)
  • Signs and symptoms of transitional cell carcinomas depend on the location and extent of the cancer. (wikipedia.org)
  • Thus, urothelial carcinomas are more common in the context of chronic urinary stone disease, chronic catheterization (as in patients with paraplegia or multiple sclerosis), and chronic infections. (wikipedia.org)
  • Transitional cell bladder carcinomas associated with this sSMS are more aggressive and invasive than those not associated with it. (wikipedia.org)
  • Berstein L, Gurney JG: Carcinomas and other malignant epithelial neoplasms. (oncolink.org)
  • Serum Antibodies to HPV16 Early Proteins Warrant Investigation as Potential Biomarkers for Risk Stratification and Recurrence of HPV-Associated Oropharyngeal Cancer. (uchicago.edu)
  • Somatic alterations of TP53 and MDM2 associated with response to enfortumab vedotin in patients with advanced urothelial cancer. (ucsf.edu)
  • These cancers can arise in the epithelial cells on the surface of the ovary. (medlineplus.gov)
  • However, researchers suggest that many or even most ovarian cancers begin in epithelial cells on the fringes (fimbriae) at the end of one of the fallopian tubes, and the cancerous cells migrate to the ovary. (medlineplus.gov)
  • And after that kidney, stomach and ovary cancers are the next most deadly. (healthybladderclub.com)
  • An intronic variant ( Int7G24A ) of TGF-β receptor type I ( TGFBR1 ) is associated with kidney and bladder cancers in our recent study. (aacrjournals.org)
  • Ovarian cancer is a disease that affects women. (medlineplus.gov)
  • In about 90 percent of cases, ovarian cancer occurs after age 40, and most cases occur after age 60. (medlineplus.gov)
  • The most common form of ovarian cancer begins in epithelial cells, which are the cells that line the surfaces and cavities of the body. (medlineplus.gov)
  • In about 10 percent of cases, ovarian cancer develops not in epithelial cells but in germ cells, which are precursors to egg cells, or in hormone-producing ovarian cells called granulosa cells. (medlineplus.gov)
  • In its early stages, ovarian cancer usually does not cause noticeable symptoms. (medlineplus.gov)
  • Having one or more of these symptoms does not mean that a woman has ovarian cancer. (medlineplus.gov)
  • Ovarian cancer is diagnosed in about 22,000 women in the United States each year. (medlineplus.gov)
  • When the term "ovarian cancer" is used, it includes both fallopian tube and peritoneal cancers because it may be unclear where the cancer started. (cancer.net)
  • Just as with ovarian cancer, some peritoneal cancers may begin in the fallopian tubes and spread from the end of the fallopian tube into the peritoneal cavity. (cancer.net)
  • Effect of vascular endothelial growth factor on regeneration of bladder acellular matrix graft: histologic and functional evaluation. (ucsf.edu)
  • Because cancers that begin in the ovaries, fallopian tubes, and peritoneum are so similar and spread easily from one of these structures to the others, they are often difficult to distinguish. (medlineplus.gov)
  • This is the first page of Cancer.Net's Guide to Ovarian, Fallopian Tube, and Peritoneal Cancer. (cancer.net)
  • In this guide, this group of cancers is referred to as "ovarian/fallopian tube cancer" because peritoneal cancer is relatively rare. (cancer.net)
  • see more information below), and in most cases, the cancer actually starts in the tip, or outer end, of the fallopian tubes. (cancer.net)
  • Based on this updated knowledge, when discussing contraception to avoid future pregnancy, some doctors recommend removal of the fallopian tubes, rather than tying or banding the tubes, in order to lower the risk of ovarian/fallopian tube cancers. (cancer.net)
  • Rarely, peritoneal cancer can develop after ovaries and fallopian tubes have been removed. (cancer.net)
  • Magnetic resonance imaging (MRI) of the bladder is superior to computed tomography (CT) for disease staging, specifically in differentiating T1 from T2 disease, and may lead to a change in treatment approach in patients at high risk of an invasive tumour. (bvsalud.org)
  • The mechanistic data for all types of can be used to identify and organize fects (e.g. is able to induce genotox- ionizing radiation ( IARC, 2012f) are mechanistic information related to icity or affect similar pathways), but particularly informative with regard to cancer induction. (who.int)
  • Doug Cress, PhD received notification of an R21 award from NCI to support the project "Molecular Drivers of Lung Cancer in Hispanics" as contact MPI. (moffitt.org)
  • New Publication: Tumor-infiltrating lymphocyte treatment for anti-PD-1-resistant metastatic lung cancer: a phase 1 trial. (moffitt.org)
  • The Int7G24A allele was evident in 32% of patients with preinvasive neoplasms and 48% of patients with invasive breast cancers compared with 26% controls ( P = 0.00008). (aacrjournals.org)
  • In addition, 11 (5.6%) homozygous Int7G24A carriers were found in patients with invasive breast cancers, whereas only 3 (2%) homozygous carriers were found in the control group. (aacrjournals.org)
  • EVIDENCE SYNTHESIS: Patients should be counselled regarding risk factors for bladder cancer. (bvsalud.org)
  • While a grade describes the appearance of cancer cells and tissue, a cancers stage explains how large the primary tumor is and how far the cancer has spread in the patients body. (healthyskinworld.com)
  • For cases for which a cancer signal was detected in patients with cancer, the prediction of the original site of the cancer by the MCED test was accurate in 85.2% of cases. (medscape.com)
  • Except in a few cases, the vast majority of published work on p53 antibodies in cancer patients use wild-type p53 as the antigen to detect these antibodies and it is unclear that they can recognize p53 mutants carried by cancer patients at all. (encyclopedia.pub)
  • This study aimed to establish a prognostic nomogram for predicting overall survival (OS) and cancer-specific survival (CSS) of patients with early-onset endometrial cancer (EOEC). (preprints.org)
  • The immunotherapy module will review the mechanism of action, toxicities, dose adjustments, and important monitoring parameters of immunotherapy agents in the treatment of cancer patients. (hoparx.org)
  • Wieneke JA, Thompson LD, Heffess CS: Adrenal cortical neoplasms in the pediatric population: a clinicopathologic and immunophenotypic analysis of 83 patients. (oncolink.org)
  • Chemical exposure, such as those sustained by workers in the petroleum industry, the manufacture of paints and pigments (e.g., aniline dyes), and agrochemicals are known to predispose one to urothelial cancer. (wikipedia.org)
  • and promoted the proliferation and invasiveness of breast cancer cells both in vivo and in vitro. (cancerindex.org)
  • Cancer stem cells (CSCs) represent a distinct group of cells within cancerous tissue that possess the ability to initiate tumorigenesis and exhibit potency, self-renewal, and drug resistance. (bmrat.org)
  • ZNF326 promotes a malignant phenotype of breast cancer by interacting with DBC1. (cancerindex.org)
  • Mechanistically, co-immunoprecipitation and immunofluorescence assays both demonstrated that ZNF326 interacted with deleted in breast cancer-1 (DBC1) in breast cancer cells. (cancerindex.org)
  • Therefore, we concluded that ZNF326 is highly expressed in breast cancer, is associated with poor prognosis, and plays a vital role in promoting the malignant phenotype of breast cancer cells by interacting with DBC1. (cancerindex.org)
  • Association analysis identifies 65 new breast cancer risk loci. (cancerindex.org)
  • Breast cancer risk is influenced by rare coding variants in susceptibility genes, such as BRCA1, and many common, mostly non-coding variants. (cancerindex.org)
  • Here we report the results of a genome-wide association study of breast cancer in 122,977 cases and 105,974 controls of European ancestry and 14,068 cases and 13,104 controls of East Asian ancestry. (cancerindex.org)
  • The prolyl oligopeptidase inhibitor SUAM-14746 attenuates the proliferation of human breast cancer cell lines in vitro. (cancerindex.org)
  • The effects of POP inhibition and knockdown on the proliferation of cultured human estrogen receptor-positive (ER+) MCF7 and T47D, and ER-negative (ER-) MDA-MB-231 breast cancer cell lines and the MCF12A non-tumorigenic epithelial cell line were tested by analyzing their influence on cell proliferation (WST-1 assay), cell viability (trypan blue exclusion assay), and cell cycle arrest (cell cycle analysis, cell cycle regulator proteins expression). (cancerindex.org)
  • The transforming growth factor-β (TGF-β) signaling pathway has been frequently implicated in breast cancer. (aacrjournals.org)
  • A separate study with a larger sample size is warranted to validate the association of the Int7G24A with human breast cancer. (aacrjournals.org)
  • This study reported a woman with breast cancer. (magiran.com)
  • Suzette Delaloge, MD, MSc, oncologist, breast cancer specialist, and director of the individualized cancer prevention program (Interception) at the Gustave Roussy Institute in Villejuif, France, looks into these "liquid biopsies" and shares her reservations about their potential marketing, especially to the organization of care plans. (medscape.com)
  • There is a necessity to better identify problematic lesions from mammography which might be most likely to contain some invasive breast most cancers. (metjesmartphonehetbosin.nl)
  • This gene is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers. (cancerindex.org)
  • p53 has a unique and unequivocal tumor suppression role, which has been confirmed by the cancer susceptibility of individuals affected by Li-Fraumeni syndrome, the p53 inactivation in most sporadic human cancers, and the spontaneous tumorigenesis in mice with the p53 gene knocked out [ 11 ] . (encyclopedia.pub)
  • Cancer incidence and survival among children and adolescents: United States SEER Program 1975-1995. (oncolink.org)