• Members of the Solute:Sodium Symporter (SSS) Family (TC# 2.A.21) catalyze solute:Na+ symport. (wikipedia.org)
  • The cotransporter is further divided into symporters and antiporters. (coredifferences.com)
  • 2016). Characterizing and evaluating the expression of the type IIb sodium-dependent phosphate cotransporter (slc34a2) gene and its potential influence on phosphorus utilization efficiency in yellow catfish (Pelteobagrus fulvidraco). (tcdb.org)
  • 2017). Characterization of the isoforms of type IIb sodium-dependent phosphate cotransporter (Slc34a2) in yellow catfish, Pelteobagrus fulvidraco, and their vitamin D3-regulated expression under low-phosphate conditions. (tcdb.org)
  • 2015). Identification of the First Sodium Binding Site of the Phosphate Cotransporter NaPi-IIa (SLC34A1). (tcdb.org)
  • The SMF is generated by primary sodium pumps (e.g. sodium/potassium ATPases, sodium translocating respiratory chain complexes) or via the action of sodium/proton antiporters. (wikipedia.org)
  • Sodium/substrate transporters are grouped in different families based on sequence similarities. (wikipedia.org)
  • A very common ATPase driven ion pump found universally in all animal cells is the sodium-potassium pump, which helps in the maintenance of membrane potential of the cells. (aakash.ac.in)
  • It helps to move three sodium ions out of the cell in exchange of every two potassium ions that is brought into the cell by directly utilising energy in the form of ATP. (aakash.ac.in)
  • A subclass of symporters that specifically transport SODIUM CHLORIDE and/or POTASSIUM CHLORIDE across cellular membranes in a tightly coupled process. (nih.gov)
  • The process is responsible for regulating the resting potential of cells by checking on the number of sodium and potassium ions present. (coredifferences.com)
  • But, if the cell sap already has a high concentration of solutes, then how does it absorb more mineral ions which are also essential for plant growth? (aakash.ac.in)
  • A symporter is where ions and solute move in the same direction. (coredifferences.com)
  • On the other hand, antiporter is where both solute and ions move in the opposite direction. (coredifferences.com)
  • Here the solute moves along the concentration gradient while the ions against the concentration gradient. (coredifferences.com)
  • The biological process involves the movement of solutes, solvents, and ions across a membrane by use of hydrostatic pressure. (coredifferences.com)
  • Sodium/substrate symport (or co-transport) is a widespread mechanism of solute transport across cytoplasmic membranes of pro- and eukaryotic cells. (wikipedia.org)
  • Almost all functionally well-characterized members normally catalyze solute uptake via Na+ symport. (wikipedia.org)
  • The PNaS family includes several functionally characterized, sodium-dependent, inorganic phosphate (P i ) transporter (NPT2 or NptA) proteins from mammals. (tcdb.org)
  • The energy stored in an inwardly directed electrochemical sodium gradient, the sodium-motive force (SMF) is used to drive solute accumulation against a concentration gradient. (wikipedia.org)
  • 2008) reported the crystal structure of a member of the solute:sodium symporter (SSS) family, the Vibrio parahaemolyticus sodium:galactose symporter, vSGLT (2XQ2​, 3DH4​). (wikipedia.org)
  • The generalized transport reaction usually catalyzed by the members of this family is: solute (out) + nNa+ (out) → solute (in) + nNa+ (in). (wikipedia.org)
  • 2022). A structure and evolutionary-based classification of solute carriers. (tcdb.org)
  • A conserved tyrosine in the first transmembrane segment of solute:sodium symporters is involved in Na+-coupled substrate co-transport. (wikipedia.org)
  • Bracher, S., Schmid, C.C., Dittmer, S.I. and Jung, H. (2016) Core transmembrane domain 6 plays a pivotal role in the transport cycle of the sodium/proline symporter PutP. (uni-muenchen.de)
  • Neurotransmitter-sodium symporter proteins utilize the transmembrane Na⫹ gradient as a driving force for transport of substrate and are further characterized by additional co-transport of Cl⫺ (2, 3, 6). (kipdf.com)
  • The human placental multivitamin symporter co-transports an anionic vitamin with two Na+. (wikipedia.org)
  • A 13 TMS topology with a periplasmic N-terminus and a cytoplasmic C-terminus has been experimentally determined for the proline:Na+ symporter, PutP, of E. coli. (wikipedia.org)
  • 2020) Sodium-coupled glucose transport, the SLC5 family, and therapeutically relevant inhibitors: from molecular discovery to clinical application. (guidetoimmunopharmacology.org)
  • An ordered binding model of sodium/substrate transport suggests that sodium binds to the empty transporter first, thereby inducing a conformational alteration which increases the affinity of the transporter for the solute. (wikipedia.org)
  • This transport of serotonin by the SERT protein terminates the action of serotonin and recycles it in a sodium-dependent manner. (wikipedia.org)
  • The energy stored in an inwardly directed electrochemical sodium gradient, the sodium-motive force (SMF) is used to drive solute accumulation against a concentration gradient. (wikipedia.org)