DiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentHealth Care
SimvastatinHydroxymethylglutaryl-CoA Reductase InhibitorsAnticholesteremic AgentsLovastatinAzetidinesHypolipidemic AgentsHeptanoic AcidsHypercholesterolemiaPravastatinMevalonic AcidPyrrolesFluorobenzenesCholesterol, LDLCholesterolPolyisoprenyl PhosphatesLipidsNiacinRhabdomyolysisDrug Therapy, CombinationDouble-Blind Method
PravastatinLovastatinStatinsAtorvastatinInhibitorsZocorRosuvastatinDosesDosePeople taking simvTabletsUses of simvastatinEffect of simvastatinOrally10mgOral simvastatinTake simvastatinDaily simvastatinAnother simvastatin20MGLowersMyocardialPatientsGenericDosageMyopathyHepaticCoronaryMedicationsDiabetesEfficacy2021LiverVytorinHypercholesterolaemiaPregnancyInflammatoryAcuteMortalityDecreaseSignificantlyGrapefruit juiceEffectsTherapyTreatmentApothekeToxicityHighAllergicPRECAUTIONS
Pravastatin7
  • Comparative assessment of environmental risk when using simvastatin, atorvastatin, rosuvastatin, pravastatin and ezetimibe from a Swedish perspective. (janusinfo.se)
  • Describe the relevance of the finding that simvastatin, but not pravastatin, seems to interfere with sleep quality and increase patient-reported sleep problems to clinicians in the care of their patients receiving statin therapy. (medscape.org)
  • The aim of this study was to investigate, and compare with pravastatin and simvastatin, the tissue-specific distribution of rosuvastatin. (aspetjournals.org)
  • Bolus intravenous doses (5 mg/kg) of radiolabeled rosuvastatin, pravastatin, and simvastatin were administered to rats, and initial uptake clearance (CL uptake ) in various tissues was calculated. (aspetjournals.org)
  • The results of this study indicated that rosuvastatin was taken up by hepatic cells more selectively and more efficiently than pravastatin and simvastatin. (aspetjournals.org)
  • 14 C]Rosuvastatin (1.15 MBq/mg), [ 14 C]pravastatin (1.17 MBq/mg), and [ 14 C]simvastatin (1.85 MBq/mg) were synthesized at Shionogi and Co., Ltd. (Osaka, Japan). (aspetjournals.org)
  • Synthetically prepared HMG-CoA reductase inhibitor with some similarities to lovastatin, simvastatin, and pravastatin. (medscape.com)
Lovastatin2
  • The ability of lovastatin, mevastatin and simvastatin to inhibit the melanoma cell proliferation was examined using cytotoxicity and apoptosis assays. (biomedcentral.com)
  • Lovastatin, mevastatin and simvastatin inhibited the growth, cell migration and invasion of HT144, M14 and SK-MEL-28 melanoma cells. (biomedcentral.com)
Statins5
  • Like other members of its class (the "statins"), simvastatin lowers total serum cholesterol and particularly low density lipoprotein (LDL) cholesterol concentrations, thereby reducing the risk of atherosclerosis and its complications - myocardial infarction and stroke. (nih.gov)
  • Simvastatin belongs to the group of medicines called statins. (mayoclinic.org)
  • More fat-soluble statins (simvastatin, atorvastatin) may be quite potent and (together with ezetimibe) represent a slightly higher risk than the others, but the levels in the environment are probably well below the concentrations that give rise to effects in Sweden. (janusinfo.se)
  • As increased stiffness leads to increased permeability via and statins have been shown to decrease RhoA activity, this investigation examined the effect of simvastatin (Zocor®), a common statin, on endothelial cell morphology, cell traction forces, cell-cell junction widths, and endothelium permeability for endothelial cells seeded on 2.5, 5, and 10 kPa polyacrylamide substrates, mimicking the stiffness of healthy and aged vessels respectively. (cornell.edu)
  • Simvastatin (Flolipid or Zocor) belongs to a class of drugs called statins and is currently the 10th most prescribed drug in America. (medika.life)
Atorvastatin2
  • Laciness, pulsing over more ordering simvastatin buy generic uncomprehensive robotry like retrocochlear, saponifying interinsular https://www.livingwithreflux.org/lwr-online-order-atorvastatin-online-new-zealand/ cadis stabbingly as regards corrugating. (livingwithreflux.org)
  • Hers get atorvastatin no script urethrometer put regradated myself benghazi, and still itself supply levels 'ezetimibe generic simvastatin buy 100mg at' a bustled choledochoduodenostomies jawbreakingly. (livingwithreflux.org)
Inhibitors2
  • Use of simvastatin is contraindicated in medications that are strong inhibitors of cytochrome P450 activity (such as cyclosporine, ketoconazole, diltiazem, ciprofloxacin or amiodarone), and dose adjustments are appropriate for its use with other agents that inhibit CYP 3A4. (nih.gov)
  • high cholesterol tablets simvastatin inhibitors such as certain drugs, but insulinsion and calcium intake may increase oxidation. (sainttammany.org)
Zocor12
  • Simvastatin, sold under the brand name Zocor among others, is a statin, a type of lipid-lowering medication. (wikipedia.org)
  • Simvastatin is available generic forms and under the commercial name of Zocor in tablets of 5, 10, 20, 40 and 80 mg. the recommended dose is 5 to 80 mg daily based upon tolerability and lipid levels. (nih.gov)
  • [3-19-2010] Based on review of data from a large clinical trial and data from other sources, the U.S. Food and Drug Administration (FDA) is informing the public about an increased risk of muscle injury in patients taking the highest approved dose of the cholesterol-lowering medication, Zocor* (simvastatin) 80 mg, compared to patients taking lower doses of simvastatin and possibly other drugs in the "statin" class. (fda.gov)
  • Simvastatin is sold as a single-ingredient generic medication and as the brand-name, Zocor. (fda.gov)
  • Zocor and the generic Simvastatin is available in the strength of 10 mg, 20 mg, 40 mg and 80 mg tablets. (canadapharmacyonline.com)
  • Zocor (Simvastatin) is a prescription medication that is used along with a proper diet to lower bad cholesterol and triglycerides in the blood and raise good cholesterol. (canadapharmacyonline.com)
  • You should not take Zocor if you are allergic to Simvastatin or if you have any other allergies. (canadapharmacyonline.com)
  • Zocor tablets contain the active ingredient simvastatin, which is a type of medicine called a statin. (dokteronline.com)
  • ZOCOR (simvastatin) is a lipid-lowering agent that is derived synthetically from a fermentation product of Aspergillus terreus . (druglib.com)
  • Cholesterol Lowering(Zocor) - why take simvastatin 40 mg at bedtime, buy zocor online, zocor price. (ecpat.at)
  • Ssri seroquel depressive Zocor Als Mg Simvastatin disorder micardis plus 80 12 5 mg nutricion para personas con diabetes cialis in thailand kaufen keppra. (ecpat.at)
  • Simvastatin is available under the following different brand names: Flolipid, Zocor. (medika.life)
Rosuvastatin1
  • However, adrenal CL uptake of simvastatin (1.55 ml/min/g tissue) was larger than hepatic CL uptake , and simvastatin was distributed to other tissues more easily than rosuvastatin. (aspetjournals.org)
Doses10
  • High doses of simvastatin are also contraindicated with the widely used antihypertensive amlodipine. (wikipedia.org)
  • There is evidence to suggest that rare side effects such as joint pain, memory loss, and muscle cramps are more likely to occur in patients who take higher doses of simvastatin. (wikipedia.org)
  • ALT elevations are clearly more frequent in patients taking higher doses of simvastatin (40 and 80 mg daily). (nih.gov)
  • The risk of myopathy is also increased when simvastatin, especially at the higher doses, is used with certain drugs (see Simvastatin Dose Limitations below). (fda.gov)
  • Be aware of the potential increased risk of muscle injury with the 80 mg dose of simvastatin compared to lower doses of simvastatin and possibly other statin drugs. (fda.gov)
  • The risk increases with higher doses and is highest for patients taking simvastatin 80 mg. (rxwiki.com)
  • High doses of orally administered simvastatin has previously been shown to improve fracture healing in a mouse femur fracture model. (biomedcentral.com)
  • In this study, simvastatin was administered either subcutaneously or directly to the fracture area, with the goal of stimulating fracture repair at acceptable doses. (biomedcentral.com)
  • We therefore conducted a number of experiments on fracture repair in which we administered the simvastatin as one daily subcutaneous injection in doses ranging from 1 to 100 mg/kg body weight. (biomedcentral.com)
  • When taken at high doses, simvastatin can build up in the blood, causing muscle problems, including weakness and pain. (cdc.gov)
Dose14
  • However, elderly patients are more likely to have age-related kidney or muscle problems, which may require caution and an adjustment in the dose for patients receiving sitagliptin and simvastatin combination. (mayoclinic.org)
  • Following an oral dose of radioactive simvastatin in humans, 13% of the radioactivity is excreted in the urine and 60% in the faeces within 96 hours. (janusinfo.se)
  • Adults (=18 years),Prevention of Cardiovascular Disease,Ezetimibe and Simvastatin Tablets is indicated in patients with coronary heart disease (CHD) and a history of acute coronary syndrome (ACS) taking their maximum tolerated dose of simvastatin and in need of additional lowering of LDL-C in the expectation of a modest further reduction in the risk of cardiovascular events following at least one year of therapy. (healthdirect.gov.au)
  • The agency is also reviewing data from other clinical trials, observational studies, adverse event reports, and data on prescription use of simvastatin to better understand the relationship between high-dose simvastatin use and muscle injury (see Data Summary below). (fda.gov)
  • Follow the recommendations in the simvastatin label regarding drugs that may increase the risk for muscle injury when used with simvastatin (see Simvastatin Dose Limitations below). (fda.gov)
  • The usual starting dose of simvastatin to reduce the risk of heart attack or stroke is 40 mg taken by mouth once a day, in the evening. (pharmasave.com)
  • High-dose simvastatin for aneurysmal subarachnoid hemorrhage: multicenter randomized controlled double-blinded clinical trial. (druglib.com)
  • Last week, the FDA recommended that doctor not start patients on an 80 mg dose of simvastatin - the highest approved dose of the drug - because of the risk of a condition known as myopathy, characterized by unexplained muscle weakness or pain. (damorelaw.com)
  • The FDA further recommended that the 80 mg dose of simvastatin should only be used by patients who have been taking it for 12 months or longer without ill effect. (damorelaw.com)
  • New patients should be started at 40 mg, and if a doctor finds that patients taking 40 mg of simvastatin aren't meeting their LDL cholesterol goal, the doctor should choose a different statin drug rather than raising the simvastatin dose to 80 mg. (damorelaw.com)
  • In this way, 10 mice received an approximate local dose of simvastatin of 0.1 mg per kg per day for the duration of the experiment and 10 mice received the vehicle compound. (biomedcentral.com)
  • Secondly, subcutaneously implanted osmotic mini-pumps were used to deliver a continuous systemic dose of simvastatin. (biomedcentral.com)
  • complications of the drug classification of proportion of a comparison of the entire dose, and especially in the men high cholesterol tablets simvastatin. (sainttammany.org)
  • Before prescribing simvastatin, your doctor may recommend genetic testing for the SLCO1B1 gene to check if simvastatin is the best statin for you or to determine what dose would work best. (cdc.gov)
People taking simv1
  • A very small number of people taking simvastatin may have mild memory problems or confusion. (bidrx.com)
Tablets13
  • These highlights do not include all the information needed to use SIMVASTATIN TABLETS safely and effectively. (nih.gov)
  • See full prescribing information for SIMVASTATIN TABLETS. (nih.gov)
  • SIMVASTATIN tablets, for oral use. (nih.gov)
  • Primary Hypercholesterolaemia,Ezetimibe and Simvastatin Tablets is indicated as adjunctive therapy to diet in patients with primary (heterozygous familial and non-familial) hypercholesterolaemia or mixed hyperlipidaemia where use of a combination product is appropriate:, Patients not appropriately controlled with a statin or ezetimibe alone. (healthdirect.gov.au)
  • Homozygous Familial Hypercholesterolaemia (HoFH),Ezetimibe and Simvastatin Tablets is indicated in patients with HoFH. (healthdirect.gov.au)
  • Children and Adolescents 10-17 years,(pubertal status: boys Tanner Stage II and above and girls who are at least one year post-menarche),Heterozygous Familial Hypercholesterolaemia (HeFH),Ezetimibe and Simvastatin Tablets is indicated as adjunctive therapy to diet in adolescent patients (10-17 years old) with heterozygous familial hypercholesterolaemia where use of a combination product is appropriate:, Patients not appropriately controlled with a statin or ezetimibe alone. (healthdirect.gov.au)
  • Homozygous Familial Hypercholesterolaemia (HoFH),Ezetimibe and Simvastatin Tablets is indicated in adolescent patients (10-17 years old) with HoFH. (healthdirect.gov.au)
  • We also carry the generic Simvastatin in the strength of 5 mg tablets. (canadapharmacyonline.com)
  • as the treatment of heart rate, the involves the US reviewed Control of PHT and PA-offairement in morning and data high cholesterol tablets simvastatin. (sainttammany.org)
  • high cholesterol tablets simvastatin ages that can also reduce the risk of heart attack or stroke in the condition, heart attacks, blood pressure medication and both of the endothelial function of blood pressure medications. (sainttammany.org)
  • Chronic kidney disease is the firster and prevention of diabetes and hypothyroidism high cholesterol tablets simvastatin . (sainttammany.org)
  • high cholesterol tablets simvastatin Choose can occurred in patients with the risk of successful warfarin, and high blood pressure high cholesterol tablets simvastatin . (sainttammany.org)
  • high cholesterol tablets simvastatin They are designed to magnesium that prevent organizations such as a low-rich foods. (sainttammany.org)
Uses of simvastatin1
  • The primary uses of simvastatin are to treat dyslipidemia and to prevent atherosclerosis-related complications such as stroke and heart attacks in those who are at high risk. (wikipedia.org)
Effect of simvastatin1
  • Effect of simvastatin topical use on alveolar bone after tooth extraction: a scoping review. (bvsalud.org)
Orally3
  • Simvastatin (sim" va stat' in) is an orally available inhibitor of hepatic 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, the major rate-limiting enzyme in cholesterol synthesis. (nih.gov)
  • Take simvastatin orally once daily in the evening. (nih.gov)
  • Patients in the simvastatin group took simvastatin 20 mg orally daily during two perioperative periods: from the 7th to the 5th preoperative day and from the 2nd day after decannulation until the 7th postoperative day. (hindawi.com)
10mg3
  • 10mg Simvastatin on alternate days and still. (spacedoc.com)
  • Simvastatin 10mg, 20mg, and 40 mg contain red and yellow ferric oxide. (hipaaspace.com)
  • Self-praising, a koupit baclofen baklofen 10mg 25mg levné elmiest Cavell quasi-idealistically resumes more pteridospermae "prodej simvastatin" aside a idolisation. (vysocina.cz)
Oral simvastatin2
  • However, few studies have revealed the effects of perioperative oral simvastatin on post-CPB changes in cardiac muscle autophagy or the influence of the degree of autophagy on postoperative cardiac function and prognosis [ 8 , 9 ]. (hindawi.com)
  • 36 animals were divided into control group (C) receiving oral saline and Simvastatin (S) who received oral simvastatin. (bvsalud.org)
Take simvastatin1
Daily simvastatin2
  • Lianne C. Krab, of the Erasmus MC University Medical Center in Rotterdam, the Netherlands, and colleagues analyzed data from 62 children with NF1 who were randomized to receive daily simvastatin or placebo for 12 weeks. (contemporarypediatrics.com)
  • With daily simvastatin injections, no effects could be demonstrated for any of the parameters examined. (biomedcentral.com)
Another simvastatin1
  • Use another simvastatin product to initiate dosing in such patients. (nih.gov)
20MG2
  • Simvastatin 20mg preisvergleich weltbild, staffel. (ecpat.at)
  • G&bl viagra artritis traumatica Novonorm Simvastatin hombro espondilitis anquilosante cialis 20mg nebenwirkung küche krebs asma embrion tratamiento. (ecpat.at)
Lowers2
Myocardial1
  • To investigate the effect and mechanism of simvastatin on myocardial injury in cardiac valve surgery with CPB. (hindawi.com)
Patients16
  • Patients cannot breastfeed while on simvastatin due to potentially disrupting the infant's lipid metabolism. (wikipedia.org)
  • Current indications for simvastatin are hypercholesterolemia and reduction in risk for death from coronary, cerebrovascular and peripheral artery disease in patients with these diseases. (nih.gov)
  • Up to 5% of patients taking simvastatin chronically may experience minor elevations in serum ALT levels during therapy, but confirmed elevations to above three times the upper limit of normal (ULN) occur in only 1% to 2% of patients. (nih.gov)
  • In several studies, ALT elevations were no more frequent in patients taking 10 and 20 mg of simvastatin daily than in placebo recipients. (nih.gov)
  • Simvastatin 80 mg daily dosage is restricted to patients who have been taking simvastatin 80 mg daily chronically (e.g., for 12 months or more) without evidence of muscle toxicity. (nih.gov)
  • For patients that require a high-intensity statin or are unable to achieve their LDL-C goal receiving simvastatin 40 mg daily, prescribe alternative LDL-C lowering treatment. (nih.gov)
  • Temporarily discontinue simvastatin in patients experiencing an acute or serious condition at high risk of developing renal failure secondary to rhabdomyolysis. (nih.gov)
  • Inform patients of the risk of myopathy and rhabdomyolysis when starting or increasing simvastatin dosage. (nih.gov)
  • Simvastatin is indicated in patients at high risk of CHD (with or without hypercholesterolaemia), including patients with diabetes , history of stroke or other cerebrovascular disease, peripheral vessel disease, or with existing CHD to reduce the risk of cardiovascular death, major cardiovascular events including stroke, and hospitalisation due to angina pectoris . (healthdirect.gov.au)
  • Patients provided written informed consent and were randomly divided into 2 groups (65 in the simvastatin group and 65 in the control group) by assigning random numbers from a random number table. (hindawi.com)
  • The aim of this study was to evaluate the influence of simvastatin on inflammatory markers in patients with COPD. (nih.gov)
  • Fifty-six patients (aged 44-80 years) with stable COPD (a mean forced expiratory volume in 1 second [FEV1] 55%), were randomly assigned (1:1) to receive simvastatin 40 mg/day or to receive no statin treatment. (nih.gov)
  • In COPD patients, a 3-month treatment with simvastatin does not reduce circulating inflammatory markers. (nih.gov)
  • Simvastatin as an adjuvant therapy to fluoxetine in patients with moderate to severe major depression: A double-blind placebo-controlled trial. (druglib.com)
  • We aimed to investigate the antidepressant effects of simvastatin as an adjuvant therapy in patients with moderate to severe depression. (druglib.com)
  • Cardiovascular and inflammatory effects of simvastatin therapy in patients with COPD: a randomized controlled trial. (druglib.com)
Generic14
  • Simvastatin is available as a generic medication, and is on the World Health Organization's List of Essential Medicines. (wikipedia.org)
  • The generic Simvastatin comes from Canada also called Teva Simvastatin manufactured by Teva and the UK by a different manufacturer. (canadapharmacyonline.com)
  • Simvastatin is also available without a brand name, ie as the generic medicine. (dokteronline.com)
  • Simvastatin, are canadian generic drugs safe, london meds. (ecpat.at)
  • Simvastatin And Ed Generic Medications For Ed and Low T3 Causes Sexual Dysfunction In Men treatment of prostate cancer may cause impotence (erectile dysfunction or ED). Purchasing generic cialis from online pharmacy is very comfortable! (ecpat.at)
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  • Hippodrome as soon buy cheap reglan without prescription as quasi-faithful squeaked - visibility on top of nonslaveholding inexpressibly www.livingwithreflux.org rescues the celebs buy generic simvastatin ezetimibe at 100mg generic nexium europe on behalf of you gondi. (livingwithreflux.org)
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Dosage3
  • Maximum recommended dosage is simvastatin 40 mg once daily. (nih.gov)
  • See full prescribing information for simvastatin dosage modifications due to drug interactions. (nih.gov)
  • Myopathy and Rhabdomyolysis: Risk factors include age 65 years or greater, uncontrolled hypothyroidism, renal impairment, concomitant use with certain other drugs, and higher simvastatin dosage. (nih.gov)
Myopathy2
  • Discontinue simvastatin if markedly elevated CK levels occur or myopathy is diagnosed or suspected. (nih.gov)
  • Myopathy and rhabdomyolysis are listed as possible side effects in the simvastatin and other statin drug labels. (fda.gov)
Hepatic2
  • The cause of hepatic injury from simvastatin is unknown. (nih.gov)
  • Coadministration with these agents may cause increases in simvastatin levels and potentiate its hepatic or muscle toxicity. (nih.gov)
Coronary1
  • Simvastatin can also be used to reduce the risk of coronary heart disease in people who have already had a heart attack, or who suffer from angina or diabetes. (dokteronline.com)
Medications2
  • Review their medical history and current medications with their healthcare professional to determine if they should continue using simvastatin. (fda.gov)
  • Individuals should be screened for the G6PD defect before being treated with certain drugs such as certain antibiotics, antimalarials and other medications simvastatin and high blood sugar known to trigger hemolysis in G6PD deficient individuals. (ggim.in)
Diabetes4
  • The Heart Protection Study evaluated the effects of simvastatin in people with risk factors including existing cardiovascular disease, diabetes, or stroke, but having relatively low LDL cholesterol. (wikipedia.org)
  • Sitagliptin and simvastatin combination is used together with a proper diet and exercise to treat type 2 diabetes. (mayoclinic.org)
  • Prior to initiating therapy with simvastatin, secondary causes of hypercholesterolaemia (e.g. poorly controlled diabetes mellitus, hypothyroidism , nephrotic syndrome , dysproteinaemias, obstructive liver disease, other drug therapy, alcoholism ) should be identified and treated. (healthdirect.gov.au)
  • blood sugar level 111 Fasting Blood Sugar How Do You Get Diabetes simvastatin and high blood sugar GGIM. (ggim.in)
Efficacy3
  • The use of simvastatin was not associated with cognitive improvements in children with neurofibromatosis type 1, contrary to findings in mouse models suggesting efficacy of this treatment, according to research published in the July 16 issue of the Journal of the American Medical Association. (contemporarypediatrics.com)
  • TUESDAY, July 15 (HealthDay News) -- The use of simvastatin was not associated with cognitive improvements in children with neurofibromatosis type 1 (NF1), contrary to findings in mouse models suggesting efficacy of this treatment, according to research published in the July 16 issue of the Journal of the American Medical Association . (contemporarypediatrics.com)
  • Simvastatin is a hypolipemic drug with proven efficacy in the prevention of cardiovascular diseases. (nih.gov)
20211
  • Fass environmental information for Simvastatin Teva by Teva (downloaded 2021-06-28). (janusinfo.se)
Liver11
  • Simvastatin is contraindicated with pregnancy, breastfeeding, and liver disease. (wikipedia.org)
  • Simvastatin is a commonly used cholesterol lowering agent (statin) that is associated with mild, asymptomatic and self-limited serum aminotransferase elevations during therapy, and rarely with clinically apparent acute liver injury. (nih.gov)
  • Clinically apparent liver injury due to simvastatin is rare. (nih.gov)
  • Rare cases of acute liver failure and death have been attributed to simvastatin. (nih.gov)
  • But in view of the wide use of simvastatin, clinically apparent liver injury is exceeding rare and is estimated to occur in 1 per 100,000 patient years of exposure. (nih.gov)
  • Simvastatin is metabolized to some extent in the liver (via CYP 3A4) and is excreted in bile. (nih.gov)
  • Simvastatin works by reducing the production of cholesterol by the liver. (dokteronline.com)
  • Simvastatin decreases the production of LDL cholesterol by blocking the action of the enzyme in the liver (called HMG-CoA reductase) that is responsible for its production. (dokteronline.com)
  • Your doctor will probably order a blood test to measure liver function before you start taking simvastatin. (rxwiki.com)
  • Simvastatin was less liver-specific (it also distributed to the spleen and adrenal). (aspetjournals.org)
  • Some people have a specific change in this gene that causes less of a statin called simvastatin to be taken into the liver. (cdc.gov)
Vytorin2
  • Simvastatin is also available as a fixed combination with ezetimibe under the brand name Vytorin. (nih.gov)
  • Compare Simvastatin / Ezetimibe (Vytorin) prices available at Canadian and international online pharmacies with local U.S. pharmacy coupon prices. (pharmacychecker.com)
Hypercholesterolaemia2
  • Simvastatin is indicated as an adjunct to diet for treatment of hypercholesterolaemia. (healthdirect.gov.au)
  • Simvastatin is used to lower cholesterol in people who have high levels either due to genetics (familial hypercholesterolaemia) or as a result of diet and lifestyle. (dokteronline.com)
Pregnancy1
  • Pregnancy must be avoided while on simvastatin due to potentially severe birth defects. (wikipedia.org)
Inflammatory1
  • After 2 weeks as well as 3 months of simvastatin treatment, no significant reduction of any measured inflammatory markers was observed. (nih.gov)
Acute1
  • Simvastatin in the acute respiratory distress syndrome. (druglib.com)
Mortality1
  • In heart protection studies, simvastatin showed the ability to lower LDL cholesterol by about 1·5 mmol/L, which resulted in substantial reductions in mortality rates. (wikipedia.org)
Decrease1
  • Simvastatin also causes a small decrease in the production of other 'bad fats' in the blood called triglycerides, and a small increase in the level of HDL cholesterol. (dokteronline.com)
Significantly2
  • Simvastatin also reduced the numbers of other events like heart attacks, strokes, and revascularizations and MI significantly. (wikipedia.org)
  • Seven RCTs assessed pain outcomes, simvastatin did not significantly affect pain in six studies. (bvsalud.org)
Grapefruit juice2
  • Grapefruit and grapefruit juice may interact with simvastatin. (rxwiki.com)
  • People are typically advised to avoid combining simvastatin and grapefruit products (such as grapefruit or grapefruit juice). (ecpat.at)
Effects13
  • Appropriate studies have not been performed on the relationship of age to the effects of sitagliptin and simvastatin combination in the pediatric population. (mayoclinic.org)
  • The risk of environmental effects of simvastatin cannot be excluded when ecotoxicological data are missing. (janusinfo.se)
  • The present clinical randomized controlled trial explored the protective effect of perioperative simvastatin on cardiac muscle after CPB and the relationship of such effects to cardiomyocyte autophagy. (hindawi.com)
  • Our results show that HMGR inhibition by simvastatin induces anxiogenic-like effects in the social interaction but not in the elevated plus-maze test, and improves memory consolidation in the inhibitory avoidance task. (nature.com)
  • Report any side effects with simvastatin to FDA's MedWatch program using the information at the bottom of the page in the "Contact Us" box. (fda.gov)
  • Our data suggest that simvastatin may be beneficial in preventing atherosclerosis beyond its traditional lipid lowering effects b y decreasing monolayer permeability due to vascular stiffening that naturally occurs with aging. (cornell.edu)
  • Common side effects of simvastatin include muscle and joint soreness, nausea, and constipation. (rxwiki.com)
  • Serious side effects have been reported with simvastatin. (rxwiki.com)
  • This is not a complete list of simvastatin side effects. (rxwiki.com)
  • Diarrhea, gas, and nausea are a few common Simvastatin side effects. (ecpat.at)
  • In general, positive bone formation and the absence of adverse effects directly linked to topical simvastatin were observed across the study models. (bvsalud.org)
  • Intra-alveolar simvastatin post- tooth extraction has been to be shown to be effective and safe for preserving alveolar bone , with varied concentrations and carriers, with no significant adverse effects . (bvsalud.org)
  • CLINICAL RELEVANCE This review provides critical insights into the effects of simvastatin on alveolar bone regeneration , informing potential benefits and possible challenges associated with its post-extraction application. (bvsalud.org)
Therapy1
  • Isolated cases of an autoimmune hepatitis-like syndrome associated with simvastatin therapy have been reported, some of which did not reverse completely with discontinuation, resulting in a chronic hepatitis requiring long term immunosuppressive therapy. (nih.gov)
Treatment6
  • Given the current available information, simvastatin should not be recommended solely for the treatment of AMD. (wikipedia.org)
  • 50% during simvastatin treatment. (nih.gov)
  • This study found a dramatic positive effect on biomechanical parameters of fracture healing by simvastatin treatment directly applied to the fracture area. (biomedcentral.com)
  • Cialis is indicated for the treatment of erectile dysfunction lipitor or simvastatin . (onlinehome.us)
  • Ma vie a chang lipitor or simvastatin .A de C. Viagra is indicated for the treatment of erectile dysfunction in men. (onlinehome.us)
  • The study evaluated simvastatin in the treatment of periodontal disease (PD) in rats. (bvsalud.org)
Apotheke1
  • Online Apotheke Holland Viagra lipitor or simvastatin . (onlinehome.us)
Toxicity1
High10
  • Simvastatin has high potential for bioaccumulation. (janusinfo.se)
  • Simvastatin is a prescription medication used to treat high cholesterol , high triglycerides, and disease of the heart and blood vessels. (rxwiki.com)
  • In the realm Low Blood Sugar Symptoms blood sugar level 111 of pharmaceutical products, simvastatin and high blood sugar they often use the other way around glucose instead of dextrose just to trim down the confusion. (ggim.in)
  • In 2010, the European Food Safety Authority s simvastatin and high blood sugar Panel on Dietetic Products, Nutrition and Allergies published a scientific opinion on dietary reference values for the intake of carbohydrates and sugars. (ggim.in)
  • If you choose the paw pad for your testing site, it simvastatin and high blood sugar may help to use the lancing device on the side of the paw pad, rather on the bottom part that the pet steps on when walking. (ggim.in)
  • seven 402 of 764 trials were at low risk of simvastatin and high blood sugar bias in random sequence generation and 529 692 were at low risk of bias in allocation concealment. (ggim.in)
  • Test what you know about medical science Blood Sugar simvastatin and high blood sugar by taking this quiz. (ggim.in)
  • Also, it comes with cheap test strips, which is something simvastatin and high blood sugar GGIM simvastatin and high blood sugar you need to look for. (ggim.in)
  • The tetrameric subunits are bound by simvastatin and high blood sugar non covalent bonds without disulfide bonds, the binding between dimers is stronger than the binding between subunits in dimers. (ggim.in)
  • Glucose transporter 1 in the hypothalamic glial cells simvastatin and high blood sugar mediates glucose sensing to regulate glucose production in vivo. (ggim.in)
Allergic1
  • Serious allergic reactions to simvastatin are rare. (wikipedia.org)
PRECAUTIONS1
  • See the "Simvastatin Precautions" section. (rxwiki.com)