• Among them, mesoporous silica nanoparticles (MSNs) are particularly interesting candidates for powerful drug carriers because of their unique characteristics and abilities to efficiently and specifically entrap cargo molecules. (rsc.org)
  • In recent decades, mesoporous silica nanoparticles (MSNs) have been proven to be excellent solid supports owing to their superior properties. (rsc.org)
  • As pharmaceutical excipients, mesoporous silica nanoparticles (MSNs) have attracted considerable concern based on potential risks to the public. (frontiersin.org)
  • In this study, the effects of intracellular delivery of various concentrations of gallic acid (GA) as a semistable antioxidant, gallic acid-loaded mesoporous silica nanoparticles (MSNs-GA), and cellular uptake of nanoparticles into Caco-2 cells were investigated. (springer.com)
  • For MSNs-GA, cell viability was reduced as a function of incubation time and different concentrations of nanoparticles. (springer.com)
  • In this study, a CD44 and N-cadherin dual targeting drug delivery system based on mesoporous silica nanoparticles (MSNs) has been successfully constructed for inhibiting tumour cell invasion and metastasis. (researcher-app.com)
  • Novel polyurethane nanocomposite (PUN) materials containing different surface-functionalized mesoporous silica nanoparticles (MSNs) were prepared by in situ polymerization methodology. (ac.rs)
  • PY - 2021 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/4016 AB - Novel polyurethane nanocomposite (PUN) materials containing different surface-functionalized mesoporous silica nanoparticles (MSNs) were prepared by in situ polymerization methodology. (ac.rs)
  • The mesoporous silica particles (MSNs) have been investigated as potential drug delivery carriers. (rjptonline.org)
  • 2015 ) reported that intravenous injection (IV) of silica nanoparticles showed significant capture of the particles in the liver and induced hepatic injury. (frontiersin.org)
  • Nanosized mesoporous silica particles with high colloidal stability attract growing attention as drug delivery systems for targeted cancer treatment and as bioimaging devices. (cipsm.de)
  • The optical response exhibited by a complex hybrid system integrated by Pt ultrasmall fluorescent particles and plasmonic Ag nanoparticles is reported. (optica.org)
  • GE&R amine functionalized silica nanoparticles are synthesized using a Stober method to provide high purity spherical particles with narrow size distribution. (geandr.com)
  • Silica nanoparticles particles have good thermal security and substance reactivity. (barcelona-tourist-apartments.com)
  • In the case of base catalysed method in alcohol, formation of stabilized emulsions with different sizes and their effect on the size and shape of silica particles was proposed. (iyte.edu.tr)
  • Carbonization of these materials were performed to obtain nanosized silica particles with low energy perimeters successfully. (iyte.edu.tr)
  • Chapter 2 describes the synthesis and characterization of the porous silica-based materials employed in the thesis: silica monolithic aerogels, silica submicron-sized particles and composite core(iron oxide)-shell(silica) nanoparticles. (uab.cat)
  • Chapter 4 explains the use of biopolymers to coat the silica-based particles conferring them with enhanced properties for biomedical uses, such as sustain drug release and improved features for the interactions with cells. (uab.cat)
  • 3. Voycheva C. Tzankov B. Tzankova D. Avramova K. Yoncheva K. Formulation of Tablets Containing Glimepiride-loaded Mesoporous Silica Particles. (rjptonline.org)
  • 6. Tzankov B. Voycheva C. Yordanov Y. Aluani D. Spassova I. Kovacheva D. Lambov N. Tzankova V. Development and in vitro safety evaluation of pramipexole-loaded hollow mesoporous silica (HMS) particles. (rjptonline.org)
  • 9. Popova T. Tzankov B. Voycheva C. Yoncheva K. Lambov N. Development of advanced drug delivery systems with bicalutamide based on mesoporous silica particles. (rjptonline.org)
  • Taking into account particle size constraints for tumor targeting (pore size of tumor endothelium and trapping effects because of reticulo-endothelial system limit the dimension of effectively employable particles to less than 380 nm), a suitable compromise is represented by the employment of 330-nm silica nanospheres at a concentration of about 1 to 2 × 10 11 part/mL. (cnr.it)
  • Furthermore, also the sensitivity of the developed method for automatic nanoparticle detection had a maximum (72.8%) with 330-nm particles, whereas it was lower with both bigger and smaller particles (being equal to 64.1% and 17.5%, respectively). (cnr.it)
  • The surface plasmon resonance can be tuned by varying the size or shape of the nanoparticles, leading to particles with tailored optical properties for different applications. (ostatic.com)
  • 7 , 14 ) (See: NIOSH Science Blog, N95 Respirators and Surgical Masks , Section on "How do filters collect particles" and Respiratory Protection for Workers Handling Engineered Nanoparticles . (cdc.gov)
  • The terms ultrafine particle and nanoparticle are often used interchange- and do not necessarily represent the view of the National Institute for ably, although nanoparticle generally refers to engineered particles. (cdc.gov)
  • Hu X, Hao X, Wu Y, Zhang J, Zhang X, Wang PC, Zou G, Liang XJ (2013b) Multifunctional hybrid silica nanoparticles for controlled doxorubicin loading and release with thermal and pH dual response. (springer.com)
  • Multifunctional mesoporous silica nanoparticles (MSN) have attracted substantial attention with regard to their high potential for targeted drug delivery. (cipsm.de)
  • This Perspective describes recent breakthroughs in mesoporous silica nanoparticle design to demonstrate their high potential as multifunctional drug delivery nanocarriers. (cipsm.de)
  • A nanothin SiO2 shell around these multifunctional nanoparticles leaves intact their morphology, magnetic and plasmonic properties but minimizes the release of toxic Ag+ ions from the nanosilver surface and its direct contact with live cells. (scilifelab.se)
  • My assigned project under the supervision of Dr. Anna Roig and Dr. Concepción Domingo was focused on the preparation of multifunctional silica-based nanoparticles for biomedical applications. (uab.cat)
  • Chapter 1 provides a general introduction to nanotechnology and colloidal science (with a special mention to nanomedicine) together with the main strategies to synthesize both silica and iron oxide nanoparticles and their biomedical applications. (uab.cat)
  • Iron oxide nanoparticles (IONP) have recently surged in production and use in a wide variety of biomedical and environmental applications. (cdc.gov)
  • Hu H, Nie L, Feng S, Suo J (2013a) Preparation, characterization and in vitro release study of gallic acid loaded silica nanoparticles for controlled release. (springer.com)
  • Progress on phthalocyanine-conjugated Ag and Au nanoparticles: Synthesis, characterization, and photo-physicochemical properties by: Shereen A. Majeed, et al. (uitm.edu.my)
  • This article by NIOSH describes a study in which gold mine dust samples underwent gravimetric analysis, quantification of silica, and characterization via aerodynamic and scanning mobility particle sizers. (cdc.gov)
  • abstract = "Silica nanoparticles coated with iron hydroxide and smectite are a major constituent of {\textquoteleft}iddingsite{\textquoteright} veins in the Nakhla meteorite. (bris.ac.uk)
  • abstract = "A mild protocol that allows the template removal of soft un-aged silica nanoparticles was investigated. (aston.ac.uk)
  • The Nanoparticles readily engage in chemical reactions with other compounds and display notable biological functionality within organisms, showing positive cytocompatibility and biodegradability. (lions103fukuoka.com)
  • The focus of this study is to investigate the effects of some parameters influencing oil recovery process due to nanoparticles such as particle size, rock permeability, initial rock wettability, injection rate and temperature. (onepetro.org)
  • Silica nanoparticles are nanomaterials with special characteristics, such as as an example large unique area, large activity, large permeability, good thermal security, and substance reactivity. (barcelona-tourist-apartments.com)
  • Silica nanoparticles constitute nanomaterials having distinctive properties, such as high specific surface area, elevated activity, noteworthy permeability, outstanding thermal stability, and chemical reactivity. (lions103fukuoka.com)
  • He Q, Shi J (2012) Mesoporous silica nanoparticle based nano drug delivery systems: synthesis, controlled drug release and delivery, pharmacokinetics and biocompatibility. (springer.com)
  • Mesoporous Silica-Coated Upconverting Nanorods for Singlet Oxygen Generation: Synthesis and Performance by: Zhen Zhang, et al. (uitm.edu.my)
  • In this review, we focus on the synthesis and therapeutic (particularly, anti-cancer) applications of Curcumin loaded Silica Nanoparticles. (iscience.in)
  • To start the gelification process, water and tetraethyl orthosilicate were added to the alcoholic suspension following well-established silica synthesis [3]. (unimib.it)
  • We have formulations to make any silica particle size between 20nm and 1000nm - with available bulk pricing. (geandr.com)
  • Objectives: To experimentally investigate the acoustical behavior of silica nanoparticles within conventional diagnostic ultrasound fields and to determine a suitable configuration, in terms of particle size and concentration, for their employment as targetable contrast agents. (cnr.it)
  • Gao L, Sun J, Li Y (2011) Functionalized bimodal mesoporous silicas as carriers for controlled aspirin delivery. (springer.com)
  • Kolev I. Mihály J. Tzankov B. Momekov G. Lambov N. Yoncheva K. Carboxylic modified spherical mesoporous silicas аs drug delivery carriers International Journal of Pharmaceutics. (rjptonline.org)
  • The amorphous silica was verified by the absence of sharp peaks and the presence of a broad peak at a 2 angle of 23.8 for the XRD analysis structure in the produced NPs. (riverpublishers.com)
  • Iron oxide nanoparticle-induced neoplastic-like cell transformation in vitro is reduced with a protective amorphous silica coating. (cdc.gov)
  • Safe by design" strategies involve the modification of particle physicochemical properties to affect subsequent adverse outcomes, such as an amorphous silica coating to reduce IONP dissolution and direct interaction with cells. (cdc.gov)
  • We hypothesized that long-term exposure to a specific IONP (nFe2O3) would induce neoplastic-like cell transformation, which could be prevented with an amorphous silica coating (SiO2-nFe2O3). (cdc.gov)
  • An amorphous silica-coated but otherwise identical particle (SiO2-nFe2O3) did not induce this neoplastic-like phenotype or changes in the parameters mentioned above. (cdc.gov)
  • Overall, the presented data suggest the carcinogenic potential of long-term nFe2O3 exposure and the utility of an amorphous silica coating in a "safe by design" hazard reduction strategy, within the context of a physiologically relevant exposure scenario (low-dose/long-term), with model validation using GMA-MS. (cdc.gov)
  • Nano SiO2 powder is also known as nano-silica. (barcelona-tourist-apartments.com)
  • Here, biocompatible, SiO2-coated, Janus-like Ag/Fe2O3 nanoparticles are prepared by one-step, scalable flame aerosol technology. (scilifelab.se)
  • Therefore, these SiO2-coated Ag/Fe2O3 nanoparticles do not exhibit the limiting physical properties of each individual component but retain their desired functionalities facilitating thus, the safe use of such hybrid nanoparticles in bio-applications. (scilifelab.se)
  • Nano silica (SiO2) has an extensive range of products from manufacturing to scientific. (riverpublishers.com)
  • Amine functionalized silica nanoparticles are available dispersed in ethanol. (myshopify.com)
  • EN] The hydrolysis of diethylcyanophosphonate, DCNP (a Tabun simulant) in the presence of mesoporous silica nanoparticles (MSN) has been studied in acetonitrile:water (99.5:0.5 v/v) mixtures using 31P NMR as a suitable technique to follow the DCNP hydrolysis. (upv.es)
  • In the absence of nanoparticles, DCNP hydrolysis reached only ca. 30% for K2CO3 and DABCO and ca. 7% for Et3N after 60 min. (upv.es)
  • However, MSN-2 nanoparticles induced a very low DCNP hydrolysis. (upv.es)
  • The silica nanoparticles were prepared by the sol-gel method via two different routes first is a basecatalyzed hydrolysis reaction and the second is an acid-catalyzed hydrolysis reaction. (riverpublishers.com)
  • The assembled state of nanoparticles (NPs) within porous matrices plays a governing role in directing their biological, electronic, and catalytic properties. (ornl.gov)
  • Overall, systematic biological data suggested that intravenous injection of nanoparticles of pharmaceutical excipients substantially affected hepatic metabolism function and induced oxidative stress and inflammation, whereas oral administration exhibited milder effects compared with intravenous injection. (frontiersin.org)
  • Chung TH, Wu SH, Yao M, Lu CW, Lin YS, Hung Y, Mou CY, Chen YC, Huang DM (2007) The effect of surface charge on the uptake and biological function of mesoporous silica nanoparticles 3T3-L1 cells and human mesenchymal stem cells. (springer.com)
  • Furthermore, this silica shell hinders flocculation and allows for easy dispersion of such nanoparticles in aqueous and biological buffer (PBS) solutions without any extra functionalization step. (scilifelab.se)
  • Coating by silica can improve colloidal stability and applicability of the cores in biological environment. (cas.cz)
  • During the realization of this thesis, silica-based nanostructured materials have been synthesized, loaded with a model drug, physical and chemically modified in their surface, and preliminarily studied as potential biomedical tools analyzing their interactions with relevant biological entities and media. (uab.cat)
  • The primary element of nano-silica powder is elemental silicon, known for its remarkable chemical stability and durability in the face of high temperatures, strong acids, potent alkalis, and other challenging environments. (lions103fukuoka.com)
  • Without the necessity of ad-hoc assumptions used earlier, our simulations show that, due to adhesion with the oxide, the nanoparticles can grow in aspect ratio while in the molten state even after silicon dioxide solidifies. (lu.se)
  • Our standard silica nanoparticles are available from 20nm to 200nm in either powder form or in an aqueous dispersion. (myshopify.com)
  • For this study, we have synthesized a wide range of monodispersed iron oxide MNS, from 7 nm to 20 nm nominal size and phase transferred to aqueous media with very thin layer of silica coating using Polyhedral Oligomeric Selesquioxanes (POSS). (northwestern.edu)
  • Special attention is devoted to the chemical conformation and stability of the drug inside the silica matrices and to the in vitro release kinetics in aqueous media. (uab.cat)
  • That report may present the basic characteristics, planning techniques, plan places, and potential growth recommendations of nano silica. (barcelona-tourist-apartments.com)
  • Silica nanoparticles, referred to as nano-silica, stand for an advanced material with distinctive physical and chemical properties. (lions103fukuoka.com)
  • This paper shall present the basic traits, methods of preparation, areas of application, and potential directions for development of nano silica. (lions103fukuoka.com)
  • Nano-silica Nanoparticles exhibit heightened surface activity, owing to the profusion of atoms on their exterior. (lions103fukuoka.com)
  • Cauda V, Engelke H, Sauer A, Arcizet D, Brauchle C, Radler J, Bein T (2010) Colchicine-loaded lipid bilayer-coated 50 nm mesoporous nanoparticles efficiently induce microtubule depolymerization upon cell uptake. (springer.com)
  • Nanoparticles of silica demonstrate excellent thermal stability and chemical reactivity. (lions103fukuoka.com)
  • Finally, after complete gelification at 40°C for two weeks, xerogels underwent to thermal treatment up to ≈900 °C to obtain fully densified silica glassceramic containing dispersed nanoparticles. (unimib.it)
  • The silica microspheres are available from 250nm up to 1000nm. (myshopify.com)
  • We also offer polymer coated silica nanoparticles and high purity colloidal silica polishing slurries for CMP (Chemical mechanical planarization). (myshopify.com)
  • Kovachev P. Functionalization and Polymer Coating - Strategies to improve Drug Delivery from Mesoporous Silica Nanoparticles. (rjptonline.org)
  • polymer nanocoating on silica nanoparticles. (riverpublishers.com)
  • Our study's objectives were to explore and summarize the effects of targeting mediator on drug development using mesoporous silica with and without functionalized polymer . (bvsalud.org)
  • Silica nanoparticles has a large refractive collection, small losing, and different characteristics and may be used as a level material for visual products to boost the transmittance and reflectivity of the device. (barcelona-tourist-apartments.com)
  • Silica nanoparticles possessing high refractive index and low scattering properties prove advantageous as coating materials for optical devices. (lions103fukuoka.com)
  • The shape of metal nanoparticles embedded in dielectric matrices defines the non-linear optical properties of the composite material. (lu.se)
  • A. Hourri, T.K. Bose, J. Thoen, "Effect of silica aerosil dispersions on the dielectric properties of a nematic liquid crystal", Phys. (photonics.pl)
  • Mesoporous silica nanoparticles are viewed as a promising and flexible platform for numerous biomedical applications. (cipsm.de)
  • Chapter 3 reports on the fabrication of hybrid products for biomedical applications by impregnating silica-based materials with a therapeutic agent trough dissolution in supercritical carbon dioxide. (uab.cat)
  • In this study, we use adsorption isotherms, spectrophotometry, and small-angle neutron scattering to develop a better understanding of the effect of spatial confinement on the assembled state and catalytic performance of gold (Au) NPs in propylamine-functionalized SBA-15 and MCM-41 mesoporous silica materials (mSiO2). (ornl.gov)
  • Adsorption of polyelectrolyte-like proteins to silica surfaces and the impact of pH on the response to ionic strength. (lu.se)
  • Adsorption of the intrinsically disordered saliva protein histatin 5 to silica surfaces. (lu.se)
  • Three different sizes of hydrophilic silica nanoparticles with single particle diameter range from 7 to 40 nm were employed and have been characterized under scanning electron microscope (SEM). (onepetro.org)
  • Materials and Methods: Silica nanospheres of variable size (160, 330, and 660 nm in diameter) and concentration (10 10-10 13 part/mL) were dispersed in different custom-designed agarose-based gel samples and imaged at 7.5 MHz with a conventional echograph linked to a research platform for radiofrequency signal acquisition. (cnr.it)
  • Conclusions: Silica nanoparticles at a diameter of about 330 nm are very promising contrast agents for ultrasound imaging and specific tumor targeting at conventional diagnostic frequencies, being in particular automatically detectable with high sensitivity already at low doses. (cnr.it)
  • Acid catalysed silica production in water was similar. (iyte.edu.tr)
  • Moreover, they demonstrate the active role of the matrix: Only explicit simulations of ion impacts around the embedded nanoparticle provide the mechanism for continuous elongation up to experimental values of aspect ratio. (lu.se)
  • The silica nanoparticles showed a favorable toxicity profile and did not affect the viability of primary immune cells from the spleen in relevant concentrations. (cipsm.de)
  • Silica nanoparticles offer a promising platform for the delivery of drugs, in particular for the drugs which lack water solubility, target capability and have non-specific distribution, systematic toxicity and low therapeutic index. (iscience.in)
  • Related research investigates nanoparticle interactions with protein. (wikipedia.org)
  • Common sense suggests that viruses or bacteria are collected differently from engineered nanoparticles, silica dusts, oil mists or other types of workplace aerosols. (cdc.gov)
  • Initial Penetration of Charged and Neutralized Lead Fume and Silica Dust Aerosols through Clean, Unloaded Respirator Filters. (cdc.gov)
  • This ensures that filters in NIOSH certified respirators will collect all types of workplace aerosols - including emerging hazards such as airborne infectious organisms ( 15 ) and engineered nanoparticles ( 7 ) - with very high efficiency. (cdc.gov)
  • As the gold is removed, by cleaving agents, the MSN revert to the optical spectra typical of bare silica. (figshare.com)
  • There are numerous techniques for the planning of Silica nanoparticles, including substance vapor deposition, sol-gel process, microemulsion process, design process, and so on. (barcelona-tourist-apartments.com)
  • Several methods are available for producing Silica nanoparticles, including chemical vapor deposition, sol-gel method, microemulsion method, and template method, to name a few. (lions103fukuoka.com)
  • Experimental transmission electron microscopy micrographs of nanoparticles after high-fluence irradiation support the simulations. (lu.se)
  • Shaffer, R.E., and S. Rengasamy: Respiratory protection against airborne nanoparticles: a review. (cdc.gov)
  • Measuring the size of silica nanoparticles and pores is still difficult and unreliable, despite the multibillion-dollar production of silica worldwide. (horiba.com)
  • The contact angle variation due to nanoparticles size was also measured at room condition. (onepetro.org)
  • Nanoparticles show great potential as superior intelligent drug delivery platforms. (rsc.org)
  • 10. Popova T. Tzankov B. Voycheva Ch. Spassova I. Kovacheva D. Tzankov S. Aluani D. Tzankova V. Lambov N. Mesoporous silica MCM-41 and HMS as advanced drug delivery carriers for bicalutamide. (rjptonline.org)
  • One of the most well-known methods for addressing a drug 's solubility is mesoporous silica , which has undergone excellent development due to the conjugation of polymers and ligands that increase its effectiveness . (bvsalud.org)
  • Mesoporous silica approaches have the capacity to greatly enhance a drug 's physicochemical issues, boost therapeutic efficacy , and acquire superb features. (bvsalud.org)
  • 8. Tzankov B. Voycheva C. Aluani D. Yordanov Y. Avramova K. Tzankova V. Spassova I. Kovacheva D. Yoncheva K. Improvement of dissolution of poorly soluble glimepiride by loading on two types of mesoporous silica carriers. (rjptonline.org)