• fetal
  • They extracted nuclei from the fibroblasts of an aborted fetal monkey (a crab-eating macaque or Macaca fascicularis) and inserted them into egg cells (ova) that had had their own nuclei removed. (wikipedia.org)
  • viable
  • In genetics and developmental biology, somatic cell nuclear transfer (SCNT) is a laboratory strategy for creating a viable embryo from a body cell and an egg cell. (wikipedia.org)
  • Research is needed to determine the most viable stem cell lines and reliable ways to promote the differentiation of pluripotent stem cells into specific cell types (neurons, muscle cells, etc. (jci.org)
  • Granulocytes and monocytes, the physically largest of the white blood cell types, had a higher success rate, yielding viable embryos about 2.1 percent of the time. (redorbit.com)
  • cells
  • The aim of carrying out this procedure is to obtain pluripotent cells from a cloned embryo. (wikipedia.org)
  • Embryonic stem cells are undifferentiated cells of an embryo. (wikipedia.org)
  • The resulting egg cell was tricked into acting like an embryo, dividing and becoming all the differentiated cells of a new individual. (hubpages.com)
  • Harvard University Stem Cell Institute researchers (left to right) George Daley, Doug Melton and Kevin Eggan speak to the media about their plan to proceed with SCNT (somatic cell nuclear transfer) in embryonic stem cells. (rxpgnews.com)
  • In the HSCI experiments, aimed at understanding diseases, the nuclei will be taken from skin cells donated by patients suffering from diabetes, blood diseases, and neurodegenerative diseases. (rxpgnews.com)
  • What the researchers have demonstrated for the first time is that the effective cloning of mice can be achieved using the nuclei of peripheral blood cells. (redorbit.com)
  • Once an embryo has more than 12 cells it is not possible to determine whether any individual cell has divided within a 24-hour period. (nhmrc.gov.au)
  • Stem cells occur at all stages of human development, from embryo to adult but their versatility and numbers tend to decrease with age. (nhmrc.gov.au)
  • Embryonic stem cells, as their name suggests, are derived from the early embryo. (nhmrc.gov.au)
  • In Australia, human embryonic stem cells are derived from human embryos that are excess to the needs of patients undergoing assisted reproductive technology (ART) treatment programs and have been donated to research by the couple for whom they were created. (nhmrc.gov.au)
  • In cattle, when individual cells from 4- and 8-cell embryos and implanted in different foster mothers, they can develop normally into calves and this technique has been used routinely within cattle breeding schemes for over 10 years. (chipbennett.net)
  • Opponents have carefully explained why they oppose research using human embryos and support research that uses ethically unobjectionable sources, such as adult stem cells. (freerepublic.com)
  • Since the first isolation of usable stem cells, tremendous scientific interest has flourished over the potential of stem cell research to improve our understanding of human development and disease and potentially for cell-based therapies to cure a wide range of diseases. (spusa.org)
  • In 2006, the landscape of stem cell research changed when the creation of induced pluripotent stem cells (iPSCs) were first announced. (spusa.org)
  • Embryonic stem cells are typically derived from embryos that are four to five days old. (spusa.org)
  • Pre-implantation embryos at this stage of development are called blastocysts, hollow microscopic balls of cells. (spusa.org)
  • Embryonic stem cells have the unique ability to self-replicate indefinitely before creating specialized cells, which is one of the advantages of performing research on them. (spusa.org)
  • At this time researchers are still uncertain of what clinical differences may exist between iPS cells and embryonic stem cells, meaning that, at this time, further research on both kinds of stem cells is necessary to fully understand the medical potential of these new discoveries. (spusa.org)
  • One potential application of embryonic stem cells is the creation of new methods for testing drugs. (spusa.org)
  • An important part of this research would be the identification of how and why undifferentiated cells become differentiated. (spusa.org)
  • The discovery of hematopoietic stem cells (HSCs) provided a pioneering step in stem cell research. (asu.edu)
  • According to the US National Institutes of Health (NIH), the standard American source on stem cell research, three characteristics of stem cells differentiate them from other cell types: (1) they are unspecialized cells that (2) divide for long periods, renewing themselves and (3) can give rise to specialized cells, such as muscle and skin cells, under particular physiological and experimental conditions. (asu.edu)
  • But producing stem cells this way involves destroying embryos, another moral quagmire. (medindia.net)
  • Induced pluripotent (IP) stem cells are created by stimulating mature, already specialized, cells back into a juvenile state -- basically cloning without the need for an embryo. (medindia.net)
  • The team tweaked the SCNT procedure using new technology that helped with the nucleus transfer and the fusion of cells. (thesouthern.com)
  • Somatic-Cell Nuclear-Transfer, (SCNT), when using a human egg from one person and cells from another person, scientifically means cloning a live human embryo," said Cody. (lifelegaldefensefoundation.org)
  • This embryo will contain the controversial embryonic stem cells that will eventually be harvested from the embryo. (lifelegaldefensefoundation.org)
  • Although this process has yet to be successful, the idea is that after cell division continues to a certain point, the embryo, created by SCNT, would then be destroyed when the embryo's stem cells are ready to be harvested. (lifelegaldefensefoundation.org)
  • In this experiment, the researchers developed a protocol for using SCNT in human cells, which differs slightly from the one used in other organisms. (wikipedia.org)
  • A year later, a team led by Robert Lanza at Advanced Cell Technology reported that they had replicated Mitalipov's results and further demonstrated the effectiveness by cloning adult cells using SCNT. (wikipedia.org)
  • The NYSCF Research Institute is one of the only laboratories in the world that currently pursues all forms of stem cell research including SCNT and iPS cell techniques for creating stem cells. (eurekalert.org)
  • How the finding of mutations might affect clinical use of stem cells generated from adult cells is the subject of an ongoing debate," said Dr. Dieter Egli, NYSCF Senior Research Fellow, NYSCF - Robertson Investigator, Assistant Professor in Pediatrics & Molecular Genetics at Columbia University, and senior author on the paper. (eurekalert.org)
  • After enduring initial failures, Mitalipov observed that of the engineered cells four of the cloned embryos began growing. (biotecharticles.com)
  • A myriad number of tests were then undertaken to prove the theory that SCNT cells could lead to the production of various cell types. (biotecharticles.com)
  • An area of researchers growing popular since 2006 are the advocates of other patient-specific and genetically similar cell lines creation: production of induced Pluripotent Stem cells (iPS) through reprogramming of adult cells. (biotecharticles.com)
  • In the normal process of fertilization and embryo formation, the egg and sperm cells each have only one copy, or half, of the DNA necessary to code for a fully functioning human being. (cbhd.org)
  • The important advances were the capacity to successfully recover live frozen embryonic cells from animals that produce large yolky eggs (anamniotes such as fishes and amphibians) When this development is combined with somatic cell nuclear transfer (SCNT) it enables the genome to be recovered. (wikipedia.org)
  • genes
  • For the purpose of this report, generating an individual animal or person that derives its nuclear genes from a diploid cell taken from an embryo, fetus, or born individual of the same species. (chipbennett.net)
  • In gene cloning, DNA fragments containing genes from one organism (typically referred to as a foreign organism) are copied and amplified in a host cell - usually a bacterium - called a vector (National Human Genome Research Institute 2014). (essayempire.com)
  • involves
  • Somatic-cell nuclear transfer involves removing the DNA-containing nucleus of a cell other than an egg or sperm -- a skin cell, for example -- and implanting it into an unfertilised egg from which the nucleus has been removed. (medindia.net)
  • sheep
  • The technique involved transplanting the nucleus from an undifferentiated cell of one sheep into the egg of another sheep from which nucleus had been removed. (hubpages.com)
  • procedure
  • She is the first "cloned" primate by artificial twinning, which is a much less complex procedure than the DNA transfer used for the creation of Zhong Zhong and Hua Hua. (wikipedia.org)
  • eggs
  • In human SCNT (Somatic Cell Nuclear Transfer) experiments, these eggs are obtained through consenting donors, utilizing ovarian stimulation. (wikipedia.org)
  • Thirty hybrid embryos were created and sent to Trans Ova Genetics, which implanted the fertilized eggs in domestic cattle. (wikipedia.org)
  • sperm
  • At this point, the question may be raised as to how an embryo is created without a sperm uniting with the egg. (cbhd.org)
  • At the point of union of the sperm and egg, an embryo is created. (cbhd.org)
  • Parkinson's
  • Indeed there have been stunning failures, such as transplants that cause increased tremors in Parkinson's patients, and the creation of cancerous tumors in animals. (freerepublic.com)
  • It was anticipated that the creation of perfectly matched tissues will someday help in discovering the cure for a variety of debilitating diseases like Alzheimer's and Parkinson's disease. (biotecharticles.com)
  • Another
  • This year's SENS rejuvenation research fundraiser has three weeks to go, and there are now two challenge funds with money left to match your charitable donations: the 150,000 fund established by Michael Greve's Forever Healthy Foundation, and today Josh Triplett has added another 20,000 above and beyond his generous donations earlier in the year. (fightaging.org)
  • Another spinoff is mitochondrial gene transfer, a new way of planting parental DNA into a healthy egg to create an embryo free of harmful mutations carried by the mother. (medindia.net)
  • medical
  • Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. (fightaging.org)
  • case
  • In this case, each embryo was created by taking a nucleus from a skin cell (donated by Wood and a colleague) and inserting it into a human egg from which the nucleus had been removed. (wikipedia.org)
  • However, according to recent research and development conducted at the Case Western University, which produced prosthetic limbs similar to the ones seen in Star Wars, the ability for prosthetics to produce feeling has become closer to reality. (wikipedia.org)
  • early
  • As the team notes, the granulocytes' performance was poorer than expected due to a much higher rate of fragmentation in early embryos. (redorbit.com)