• A ) Image of N-cadherin polarized neural rosettes structures within neuroepithelial tissues derived from hPSCs using the E6 method in 6-well TCPS plates. (elifesciences.org)
  • Co-staining of neural rosettes with F-actin, ZO-1 tight junction proteins, and phospho-H3 + mitotic nuclei are provided in Figure 1-figure supplement 1 . (elifesciences.org)
  • B ) Manual quantification of polarization foci and neural rosettes within micropatterned neuroepithelial tissues of varying morphology. (elifesciences.org)
  • C ) Schematic of automated image analysis algorithm for quantification of polarization foci and neural rosettes. (elifesciences.org)
  • Neural rosettes refer to radially organized cellular structures. (creative-biolabs.com)
  • With the formation of neural rosettes, neural tube development and neural differentiation can be modeled using human pluripotent stem cells (hPSCs) in vitro . (creative-biolabs.com)
  • The neural markers expressed in neural rosettes include SOX2, PAX6, and SOX1. (creative-biolabs.com)
  • In addition, neural rosettes can differentiate into distinct region-specific neurons and glia. (creative-biolabs.com)
  • Recent research has shown that the dismantlement of neural rosettes promotes neurogenesis and astrogenesis prematurely, which means that the complete rosette structure is essential for orderly neurodevelopment. (creative-biolabs.com)
  • Fig.2 Involvement of active BMP signaling in differentiation and formation of neural rosettes. (creative-biolabs.com)
  • Besides, the mechanism of neural rosettes formation relates to secondary neurulation rather than that of primary neurulation. (creative-biolabs.com)
  • The hPSCs-based neural rosettes have been widely used as models for the research of neural tube development as well as neural differentiation in vitro . (creative-biolabs.com)
  • Calcium signaling mediates five types of cell morphological changes to form neural rosettes. (creative-biolabs.com)
  • Differentiation of neural rosettes from human pluripotent stem cells in vitro is sequentially regulated on a molecular level and accomplished by the mechanism reminiscent of secondary neurulation. (creative-biolabs.com)
  • A six-fold assembly of the trimeric computational oligomer had the lowest potential energy per monomer and was consistent with rosette CSC morphology. (osti.gov)
  • Effect of Tissue Morphology on Singular Rosette Emergence. (elifesciences.org)
  • And inhibition of BMP signaling would result in the expression of these markers and the rosette morphology. (creative-biolabs.com)
  • A ) Co-localization of F-actin, ZO-1 tight junction proteins, and phospho-H3 + mitotic nuclei within N-cadherin polarized structures confirms neural rosette formation. (elifesciences.org)
  • TGFß-treated cells exhibit ring-like structures (podosome rosettes, right panel), where vinculin surrounds F-actin cores (tbottom panel: higher magnification of the boxed areasl). (u-bordeaux.fr)
  • Neurocytic rosettes and perivascular structures stained positive for synaptophysin. (surgicalneurologyint.com)
  • 19.50/acre) on rosettes or prior to stem elongation. (unl.edu)
  • abstract = "Rosette formation is a feature that has not been described as occurring in melanocytic neoplasms. (elsevierpure.com)
  • F ) Representative images depicting stages of rosette emergence and ( G ) rate of singularity within neuroepithelial tissues on select days. (elifesciences.org)
  • Pathology showed a glioneuronal neoplasm with vague neurocytic rosettes and loose perivascular pseudorosettes. (surgicalneurologyint.com)
  • Common mullein spreads solely by seeds that typically germinate in the fall and exist as a rosette, a circular leaf formation at ground level, for a full growing season without producing a stalk or seed. (unl.edu)
  • Rosettes are used to camouflage the animal, either as a defense mechanism or as a stalking tool. (wikipedia.org)
  • In 'Analyzed' micrograph, the purple outline indicates a rosette and green outlines indicate polarization foci as determined by the image analysis workflow. (elifesciences.org)
  • The central cell processes of the rosettes were negative for trichome, type IV collagen, neurofilament protein, glial fibrillary acidic protein, and tyrosine hydroxylase. (elsevierpure.com)
  • This domesticated cat has a distinct coat pattern with a combination of rosettes, spots, and stripes. (wikipedia.org)
  • While individual cheetahs (Acinonyx jubatus) do have distinct and identifiable coat patterns like leopards or jaguars, the cheetah's patterns are considered to be spots, not rosettes. (wikipedia.org)
  • So a Ombre Rosette cake means gradient cake from dark to light and frosting decorations in the form of a rose. (laavyskitchen.com)
  • Taken together, our model and experimental observations suggest that rosettes in the VE epithelium do not form passively in response to AVE migration. (ox.ac.uk)
  • On each color variation, the leopard has rosette patterns on their backs, flanks, and limbs. (wikipedia.org)
  • Heathcliffe' features large, fully double flowers of deep rosette shape as well as a deep crimson color. (hgtv.com)
  • Using a 1M star tip from Wilton pipe little rosettes close to each other.Start from the darkest color on the bottom.Add more white frosting to remaining colored frosting so u get a lighter shade.Repeat until u reach the top. (laavyskitchen.com)
  • Three ribbons are attached in the color formation of the rosette under the stars. (cavaloop.eu)
  • Complete, floater cluster of relatively large Azurite crystals in a somewhat 'bow-tie' formation. (marinmineral.com)
  • In addition, there were multiple clods of 4 white dots in rosette formations. (medscape.com)
  • Simulations suggest that while rosettes are not essential for AVE migration, they are crucial for the orderliness of this migration observed in embryos. (ox.ac.uk)
  • On a large base rosette, 12 large tips are mounted behind a small rosette. (cavaloop.eu)
  • The large base rosette ensures the strength of the loop. (cavaloop.eu)
  • Beautiful Atacamite specimen featuring two rosette formations deep green crystals. (marinmineral.com)
  • To probe the role of rosettes during AVE migration, we develop a mathematical model of cell movement in the VE. (ox.ac.uk)
  • The role of one highly occurring phenotype in particular where infected reticulocytes cytoadhere to noninfected normocytes, forming rosettes, remains unknown. (fiocruz.br)
  • Collectively, these results showed that rosette formation plays a role in host immune response by hampering leukocyte phagocytosis. (fiocruz.br)
  • We obtained more direct evidence through generating improved transmission electron microscopy (TEM) images and image averages of the rosette-type CSC, revealing the frequent triangularity and average cross-sectional area in the plasma membrane of its individual lobes. (osti.gov)
  • H ) Schematic of experiment testing the effect of E6 subculture time point on neural rosette emergence within micropatterned neuroepithelial tissues, and ( I ) corresponding images of immunostained tissues 5 days after culture on micropatterned substrates. (elifesciences.org)
  • Hoang, MP , Rakheja, D & Amirkhan, RH 2003, ' Rosette formation within a proliferative nodule of an atypical combined melanocytic nevus in an adult ', American Journal of Dermatopathology , vol. 25, no. 1, pp. 35-39. (elsevierpure.com)
  • Our results show that the formation of multi-cellular rosettes in the mouse VE is dependent on normal PCP signalling. (ox.ac.uk)
  • Endothelial podosome rosettes in cultured endothelial cells. (u-bordeaux.fr)
  • Multi-cellular rosettes in the mouse visceral endoderm facilitate the ordered migration of anterior visceral endoderm cells. (ox.ac.uk)
  • Using both wild-type embryos as well as mutants in which AVE migration is abnormal or arrested, we show that AVE migration is specifically linked to changes in cell packing in the VE and an increase in multi-cellular rosette arrangements (five or more cells meeting at a point). (ox.ac.uk)
  • Six trimeric SAXS models nearly filled the space below an average FF-TEM image of the rosette CSC. (osti.gov)
  • In conclusion, the multifaceted data support a rosette CSC with 18 CESAs that mediates the synthesis of a fundamental microfibril composed of 18 glucan chains. (osti.gov)
  • Cheetah - the king cheetah variety has rosettes Bengal cat Jaguar Leopard - smaller, denser rosettes than the jaguar, lacking central spots Leopard cat Liger Liliger Lion - cubs have rosettes, which may be retained on the legs in adults Litigon Margay Ocelot Safari cat Snow leopard Tigon Leopard pattern Stripe (pattern) Schneider, Alexsandra (2012). (wikipedia.org)
  • A six-lobed membrane spanning cellulose synthesis complex (CSC) containing multiple cellulose synthase (CESA) glycosyltransferases mediates cellulose microfibril formation. (osti.gov)