AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsInformation ScienceHealth CareGeographicals
Retinal DegenerationPhotoreceptor Cells, VertebrateElectroretinographyRetinitis PigmentosaRetinaMacular DegenerationRhodopsinNerve DegenerationEye ProteinsPhotoreceptor CellsRetinal Rod Photoreceptor CellsPeripherinsCyclic Nucleotide Phosphodiesterases, Type 6Wallerian DegenerationDisease Models, AnimalRetinal Cone Photoreceptor CellsLightRadiation Injuries, Experimentalcis-trans-IsomerasesEye Diseases, HereditaryRetinal Pigment EpitheliumMice, Mutant StrainsDark AdaptationOpsinsPhotoreceptor Cells, InvertebrateLeber Congenital AmaurosisPigment Epithelium of EyeOphthalmoscopyRats, Mutant StrainsFundus OculiMutationIntervertebral Disc DegenerationRod OpsinsRetinal Photoreceptor Cell Outer SegmentMice, Inbred C57BLFluorescent Antibody Technique, IndirectAnimals, Genetically ModifiedBardet-Biedl SyndromeIn Situ Nick-End LabelingRetinal DiseasesVision, OcularBlindnessRod Cell Outer SegmentUsher SyndromesRetinal DysplasiaArrestinRats, TransgenicFluorescein AngiographyLipofuscinWet Macular DegenerationFrontotemporal Lobar Degenerationtrans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane DihydrochlorideMice, KnockoutMice, TransgenicVisual AcuityRetrograde DegenerationRetinal Ganglion CellsNerve Tissue ProteinsIntermediate Filament ProteinsRetinal NeuronsTransducinRetinaldehydeTomography, Optical CoherenceRecoverinGenes, RecessivePedigreeRetinal Bipolar CellsChoroidApoptosisGenes, DominantPhenotypeImmunohistochemistry3',5'-Cyclic-GMP PhosphodiesterasesDependovirusCiliary Neurotrophic FactorCell DeathCell CountMice, Inbred C3HIntervertebral DiscBlotting, WesternMicroscopy, Electron, TransmissionG-Protein-Coupled Receptor Kinase 1Drosophila ProteinsChoroideremiaReverse Transcriptase Polymerase Chain ReactionInjectionsPhotoreceptor Connecting CiliumRetinal VesselsMolecular Sequence DataSmith-Lemli-Opitz SyndromeEyeAgingLight Signal TransductionIntravitreal InjectionsCiliaVitreous BodyCharacidaeDNA Mutational AnalysisMembrane ProteinsGene Expression Regulation
MacularRetinaRetinitis PigmentosaPhotoreceptorsDetachmentDiseasesBlindnessPigment epithelialGlaucomaRetinopathyPigmentary retinal degenerationDisordersMiceOxidative stressMutationsCataractTreatment for retinalAssociated retinal breaksGeneticHemorrhageClinicalPhotoreceptor cell deathDetachmentsRisk of retinalOpticGanglion CellsNeurodegenerationPathologiesLattice DegenerationOcularDysfunction and degenerationPeripheralOcclusionGeneDiseaseSystemicProgressionGenesOptical coherenceImbalanceMicrogliaTearsDamageDisorderPatients
Macular32
Retina15
  • Another approximately 200,000 individuals are born with genetic predispositions to degeneration of the retina and progressive loss of vision throughout life. (databasefootball.com)
  • The unprecedented clinical success of VEGF antibody to inhibit the growth of "leaky" blood vessels (a process known as neovascularization) into the retina and their concomitant destruction of retinal tissue has been achieved despite a lack of knowledge regarding the primary cause of this devastating disease. (databasefootball.com)
  • Pigment epithelium-derived factor (PEDF) is a member of the serine protease inhibitor superfamily produced by retinal pigment epithelial cells in the developing and adult retina. (nih.gov)
  • This is a rare syndrome consisting of a pigmentary degeneration of the retina in association with nanophthalmos. (arizona.edu)
  • Blood from the retina is drained from smaller branches of retinal veins into the larger central retinal vein and away from the eye. (foresthillsretina.com)
  • Floaters may be a symptom of a tear in the retina, which is a serious problem because it may lead to retinal detachment. (foresthillsretina.com)
  • The retinal specialists at Retina Associates of Utah are skilled and experienced in the treatment of multiple health concerns affecting the retina, macula, vitreous, and optic nerve. (retinautah.com)
  • Lattice degeneration targets the peripheral edges of the retina. (retinautah.com)
  • No prevention or cure exists, and treatment is usually unnecessary, but lattice degeneration can make the retina more susceptible to tears, holes, and detachment. (retinautah.com)
  • Accumulation of tau and pTau were observed in both the central and peripheral retinal ganglion cell (RGC), inner plexiform and inner nuclear layers of the neurosensory retina of rTg(tauP301L)4510 mice. (biomedcentral.com)
  • y sus efectos en la retina y la visión. (ucm.es)
  • Microglia in mouse retina contralateral to experimental glaucoma exhibit multiple signs of activation in all retinal layers. (ucm.es)
  • Retinal Detachment is a condition that happens when the retina detaches from its normal position at the back of the eye, exposing it to underlying blood vessels, scar tissue, and other potentially harmful elements. (meghalayamagazine.in)
  • Proteomic profiling of the retinal dysplasia and degeneration chick retina. (omia.org)
  • Retinal detachment is separation of the neurosensory retina from the underlying retinal pigment epithelium. (msdmanuals.com)
Retinitis Pigmentosa2
Photoreceptors15
  • Retinal diseases that result in damage to photoreceptors and subsequent vision loss are some of the most heterogeneous genetic disorders known, involving over 60 different genes and more than 200 different mutations. (databasefootball.com)
  • Despite the considerable heterogeneity observed in the spectrum of retinal disease, it is known that loss of photoreceptors due to cell death is the ultimate cause of vision loss. (databasefootball.com)
  • From a variety of animal models of environmentally- and genetically-induced retinal degeneration, we know that loss of photoreceptors occurs due to an integrated network of cell death pathways, including apoptosis, necroptosis, and autophagy. (databasefootball.com)
  • Leber congenital amaurosis (LCA) associated with retinal pigment epithelium-specific protein 65 kDa (RPE65) mutations is a severe hereditary blindness resulting from both dysfunction and degeneration of photoreceptors. (upenn.edu)
  • In untreated RPE65-LCA patients, there was dysfunction and degeneration of photoreceptors, even at the earliest ages. (upenn.edu)
  • Dogs treated during the earlier dysfunction-only stage showed improved visual function and dramatic protection of treated photoreceptors from degeneration when measured 5-11 y later. (upenn.edu)
  • We hypothesized that the mutant rhodopsin in the endoplasmic reticulum (ER) generates the unfolded protein response (UPR) in retinal photoreceptors. (arvojournals.org)
  • One purpose of this study was to investigate whether ER stress is induced in transgenic mutant rhodopsin S334ter-3 rats, which, in turn, would induce the UPR and result in degeneration of photoreceptors. (arvojournals.org)
  • The second purpose of this study was to investigate whether these compounds can be used as therapeutic agents to suppress death of retinal photoreceptors in these rats. (arvojournals.org)
  • Therefore, it is essential to maintain the health and integrity of retinal photoreceptors. (nih.gov)
  • We further demonstrated that a similar proteasomal overload takes place in photoreceptors of other mutant mice where retinal degeneration has been ascribed to protein mistargeting or misfolding, but not in mice whose photoreceptor degenerate as a result of abnormal phototransduction. (duke.edu)
  • Degeneration of retinal photoreceptors is frequently observed in diverse ciliopathy disorders, and photoreceptor cilium gates the molecular trafficking between the inner and the outer segment (OS). (bvsalud.org)
  • Loss of Bmi1 causes anomalies in retinal development and degeneration of cone photoreceptors. (ulaval.ca)
  • Of these, rod and cone photoreceptors represent the functional unit of light detection and phototransduction and are frequently affected in retinal degenerative diseases. (ulaval.ca)
  • We show here that Bmi1 is required to prevent post natal degeneration of cone photoreceptors and bipolar neurons and that inactivation of Chk2 or p53 could improve but not overcome cone degeneration in Bmi1(-/-) mice. (ulaval.ca)
Detachment21
Diseases9
  • Retinal degeneration may refer to: Retinopathy, one of several eye diseases or eye disorders in humans Retinal degeneration (rhodopsin mutation) Progressive retinal atrophy, an eye disease in dogs List of systemic diseases with ocular manifestations, in humans This disambiguation page lists articles associated with the title Retinal degeneration. (wikipedia.org)
  • And yet, over 20 million Americans are living with retinal diseases for which the only prognosis is severe or complete vision loss. (databasefootball.com)
  • Despite the success of the intravitreal delivery of therapeutic protein for the treatment of neovascular and edema-related retinal disease, there has been no development of this approach for the treatment of severe loss of vision in the approximately 18 million patients inflicted with other retinal diseases. (databasefootball.com)
  • The University of Wisconsin - Madison Inherited Retinal Degeneration (IRD) Clinic was established by UW Health and the Department of Ophthalmology and Visual Sciences to offer expanded services such as specialized examinations and testing, physician consultation, genetic counseling, imaging, lab work and information about ongoing clinical trials and current research about inherited eye diseases. (wisc.edu)
  • Owing to a combination of lifestyle changes such as eating a high-fat diet and decrease in physical activity and extended life expectancy, an increasing number of people are at risk for retinal diseases, and the resulting economic burden imposed on health care systems is increasing accordingly. (hindawi.com)
  • We invite authors to contribute original research articles and reviews focusing on the role of oxidative stress in retinal diseases. (hindawi.com)
  • This special issue will stimulate further efforts to understand retinal diseases at the systems level, with the hope of finding new preconditioning and therapeutic strategies to prevent or treat retinal pathologies. (hindawi.com)
  • There is currently no treatment available for loss of vision due to optic nerve atrophy or retinal ganglion cell loss, which can be caused by end-stage glaucoma, traumatic optic atrophy, 2 and other diseases. (nature.com)
  • In Light of the first FDA approved gene therapy for an inherited retinal disease, there is a promise for many retinal degenerative diseases. (ucsd.edu)
Blindness5
  • Inherited retinal degenerations are a group of rare eye disorders caused by an inherited genetic mutation, and can result in vision loss or blindness. (wisc.edu)
  • Retinal Degenerations (RD) are the leading cause of blindness in the United States. (nih.gov)
  • The RD Fund (Retinal Degeneration Fund) is the venture arm of the Foundation Fighting Blindness, and a leading investor in the retinal disease space. (siliconvalleyjournals.com)
  • Established in 1971, the Foundation Fighting Blindness is the world's leading private funding source for retinal degenerative disease research. (siliconvalleyjournals.com)
  • Perceive was founded on compelling research elucidating two novel protective biologies for treating retinal blindness, developed from foundational collaborations in genetic science and target validation. (siliconvalleyjournals.com)
Pigment epithelial2
  • The iPS cells are then programmed to become retinal pigment epithelial cells, the type of cell that dies early in the geographic atrophy form of AMD. (nih.gov)
  • The retinal blood vessel walls were extensively hyalinized, with cell debris and deposition of basement-membrane-like material, which may have originated from perivascular pigment-laden cells of pigment epithelial origin. (elsevierpure.com)
Glaucoma3
  • These data support the hypothesis that calcineurin activation is an important mediator of RGC degeneration, and are consistent with the hypothesis that calcineurin activation may contribute to RGC neurodegeneration in glaucoma. (nyu.edu)
  • El trabajo del Instituto de Investigaciones Oftalmológicas Ramón Castroviejo está centrado en campo del glaucoma, la isquemia y las enfermedades neurodegenerativas (Alzheimer, ELA, esclerosis múltiple. (ucm.es)
  • The Role of Microglia in Retinal Neurodegeneration: Alzheimer's Disease, Parkinson, and Glaucoma. (ucm.es)
Retinopathy3
  • However, the effects of early and established stages of hypertension combined with diabetes on the development of retinopathy and possible contribution to retinal microvascular degeneration remain incompletely understood. (molvis.org)
  • The aim of the current study was to examine the effects of early and established hypertension alone or in combination with diabetes-as known risk factors for vascular damage-on development of retinopathy and retinal microvascular degeneration. (molvis.org)
  • The disorder is characterized by fat malabsorption, spinocerebellar degeneration, acanthocytic red blood cells, and pigmented retinopathy. (medscape.com)
Pigmentary retinal degeneration2
  • A case of advanced pigmentary retinal degeneration is described. (elsevierpure.com)
  • Dive into the research topics of 'Advanced pigmentary retinal degeneration. (elsevierpure.com)
Disorders4
  • Retinal disorders affect this vital tissue. (medlineplus.gov)
  • NFTs are also observed in other pathologies such as Alzheimer's disease (AD), Pick's disease, corticobasal degeneration and PSP, a group of neurological disorders collectively known as tauopathies. (biomedcentral.com)
  • Our findings provide novel insights that increase understanding of retinal degeneration in ciliopathy disorders. (bvsalud.org)
  • Spark Therapeutics (NASDAQ:ONCE), a gene therapy company based in Philadelphia, USA, has announced a new initiative to provide free genetic testing for eligible patients to obtain genetic information and counselling in respect of their progressive retinal disorders. (euretina.org)
Mice7
  • We have investigated this possibility by injecting PEDF into the eyes of homozygous retinal degeneration (rd) and retinal degeneration slow (rds) mice, two mutants displaying apoptotic photoreceptor loss. (nih.gov)
  • After 3 months, antibiotic treated mice showed significantly higher funduscopy clinical grading scores, indicative of increased focal retinal degeneration. (nih.gov)
  • In a mouse model of RP (rd10 mice), we show that oxidative DNA damage activates microglia through MutY homolog-mediated (MUYTH-mediated) base excision repair (BER), thereby exacerbating retinal inflammation and degeneration. (jci.org)
  • Dysregulated Arginine Metabolism Is Linked to Retinal Degeneration in Cep250 Knockout Mice. (bvsalud.org)
  • We used Cep250 KO mice and untargeted metabolomics to uncover potential mechanisms underlying retinal degeneration . (bvsalud.org)
  • Altogether, these results suggest that dysregulated arginine metabolism contributes to retinal degeneration in Cep250-/- mice . (bvsalud.org)
  • The retinal phenotype of Bmi1(-/-) mice was also characterized by loss of heterochromatin, activation of tandem repeats, oxidative stress and Rip3-associated necroptosis. (ulaval.ca)
Oxidative stress1
Mutations4
  • Inherited retinal degenerations, caused by mutations in over 100 individual genes, affect approximately 2 million people worldwide. (duke.edu)
  • Mutations in CLN3 (OMIM # 204200 ) lead to retinal degeneration in childhood, with additional development of cerebral neurodegeneration around the same age (classic CLN3) or up to adulthood (protracted CLN3). (jamanetwork.com)
  • 1 However, recent research claims that a subset of mutations in CLN3 , notably the R405W missense mutation, give rise to isolated retinal degeneration. (jamanetwork.com)
  • In August of this year Spark had reported that a clinical study on patients with retinal degeneration caused by RPE-65 mutations had delivered positive results in respect of visual function and full-field sensitivity testing. (euretina.org)
Cataract2
  • Cataract surgery is a risk factor for new retinal breaks. (guidelinecentral.com)
  • Cheng CS, Natividad MG, Earnest A, Yong V, Lim BA, Wong HT, Yip LW (2011) Comparison of the influence of cataract and pupil size on retinal nerve fibre layer thickness measurements with time-domain and spectral-domain optical coherence tomography. (springer.com)
Treatment for retinal1
  • The most successful treatment for retinal disease to date has been an injection of a therapeutic protein into the vitreous of patients. (databasefootball.com)
Associated retinal breaks1
  • Examine symptomatic patients who have an acute PVD to detect and treat associated retinal breaks or tears. (guidelinecentral.com)
Genetic2
  • Spark Therapeutics Inc., (NASDAQ:ONCE) announces free genetic testing and counselling services for patients with inherited retinal degenerations. (euretina.org)
  • While deciding to be tested is always a personal decision between patients and their physicians, this type of information can identify the underlying genetic cause of a person's retinal disease and help them understand how the disease may affect their vision over their lifetime. (euretina.org)
Hemorrhage1
  • Selected patients, particularly those with any degree of vitreous pigment, vitreous or retinal hemorrhage, or visible vitreoretinal traction, should be asked to return for a second examination promptly if they have new symptoms or within 6 weeks following the onset of PVD symptoms. (guidelinecentral.com)
Clinical7
  • Clinical trials with gene augmentation therapy have shown partial reversal of the dysfunction, but the effects on the degeneration are not known. (upenn.edu)
  • joining over 80,000 alone read ia for book retinal degeneration clinical at nuclear tests. (buoncore.com)
  • You should know personal book retinal degeneration clinical and laboratory applications 1993 in these companies. (buoncore.com)
  • Chiara Atik The book retinal degeneration clinical will attend integrated to your Kindle message. (buoncore.com)
  • Angliyskaya etimologiya: book retinal degeneration clinical. (buoncore.com)
  • Some interviews personalize Printed to understand ia that Have the book retinal degeneration clinical pilot, while Businesses give selections that are it. (buoncore.com)
  • Further work should aim to validate whether these observations are fully translatable to a clinical scenario, which would recommend follow-up retinal and optic nerve examination in FTD. (biomedcentral.com)
Photoreceptor cell death3
  • S334ter-3 retinal slices demonstrated the production of reactive oxygen species (ROS) and photoreceptor cell death. (arvojournals.org)
  • Chemical chaperones and TUDCA are able to partially suppress retinal photoreceptor cell death and subsequently delay RP formation in the transgenic S334ter-3 rats. (arvojournals.org)
  • RPE dysfunction and degeneration leads to photoreceptor cell death and vision loss, a common factor among several forms of RD. (nih.gov)
Detachments5
  • Educate high-risk patients about symptoms of PVD, retinal breaks, and retinal detachments as well as the need for periodic follow-up. (guidelinecentral.com)
  • Traction and serous retinal detachments (not involving retinal breaks) cause central or peripheral vision loss. (msdmanuals.com)
  • Traction and serous retinal detachments do not involve a break and are called nonrhegmatogenous. (msdmanuals.com)
  • Traction and serous (exudative) retinal detachments can cause blurriness of vision, but they may not cause any symptoms in the early stages. (msdmanuals.com)
  • Direct funduscopy using a handheld ophthalmoscope can miss some retinal detachments, which may be peripheral. (msdmanuals.com)
Risk of retinal1
  • You may be able to prevent retinal vein occlusion from occurring by properly managing any health conditions which increase the risk of retinal vascular disease. (foresthillsretina.com)
Optic3
  • Conclusions: Calcineurin activation is sufficient to cause RGC dendritic degeneration and optic nerve damage. (nyu.edu)
  • Schulze A, Lamparter J, Pfeiffer N, Berisha F, Schmidtmann I, Hoffmann EM (2011) Diagnostic ability of retinal ganglion cell complex, retinal nerve fiber layer, and optic nerve head measurements by Fourier-domain optical coherence tomography. (springer.com)
  • We combined an adaptive cortical atlas and diffusion-weighted magnetic resonance imaging (dMRI) and tractography to separate optic radiation (OR) projections to different retinal eccentricities in human primary visual cortex. (elsevierpure.com)
Ganglion Cells2
  • Retinal ganglion cells are unable to regenerate, making this condition irreversible in many cases. (nature.com)
  • Whole-eye transplantation (WET) provides the opportunity to replace diseased retinal ganglion cells, as well as the entire optical system and surrounding facial tissue, if necessary. (nature.com)
Neurodegeneration1
  • The conserved mapping between retinal and white matter damage suggests that retinal neurodegeneration might be a primary cause of white matter degeneration in AMD patients. (elsevierpure.com)
Pathologies1
  • In eyes with epiretinal membrane, measuring errors in the SD-OCT occur significantly more frequently than in eyes without any retinal pathologies. (springer.com)
Lattice Degeneration5
  • Recognize the evolution of retinal breaks and lattice degeneration. (guidelinecentral.com)
  • Lattice degeneration is a common condition, affecting about 8-10% of the general population. (retinautah.com)
  • Lattice degeneration may also develop in rare conditions impacting eye and vision health, including Stickler syndrome, Ehlers-Danlos, and Marfan syndrome. (retinautah.com)
  • As lattice degeneration itself does not cause symptoms, it is typically only detected and diagnosed during an annual dilated eye examination performed by an ophthalmologist. (retinautah.com)
  • What Does The Lattice Degeneration Eye Exam Entail? (retinautah.com)
Ocular2
  • Purpose: We previously reported that calcineurin, a Ca 2+ /calmodulin-dependent serine/threonine phosphatase, is activated and proposed that it participates in retinal ganglion cell (RGC) apoptosis in two rodent ocular hypertension models. (nyu.edu)
  • In this study, we tested whether calcineurin activation by itself, even in the absence of ocular hypertension, is sufficient to cause RGC degeneration. (nyu.edu)
Dysfunction and degeneration1
  • Dogs treated later during the combined dysfunction and degeneration stage also showed visual function improvement, but photoreceptor loss continued unabated, the same as in human RPE65-LCA. (upenn.edu)
Peripheral1
  • Central and peripheral retinal labelling of tau and phosphorylated tau (pTau) was quantified and retinal layer thicknesses and cell numbers assessed. (biomedcentral.com)
Occlusion5
Gene2
  • We evaluated the consequences of gene therapy on retinal degeneration in patients with RPE65-LCA and its canine model. (upenn.edu)
  • The effects of gene augmentation therapy are complex and suggest a need for a combinatorial strategy in RPE65-LCA to not only improve function in the short term but also slow retinal degeneration in the long term. (upenn.edu)
Disease7
  • In total, our results indicate that pigmentation of the RPE is a cornerstone of RPE-retinal interaction and support and that the receptor in the pigmentation pathway most likely underlies the racial bias of the disease. (nih.gov)
  • In our study published in Experimental Eye Research in 2018, we have made significant progress in addressing the latter two obstacles preventing the development of intravitreal protein therapy for retinal disease. (databasefootball.com)
  • The results suggest that, in RPE65 disease treatment, protection from visual function deterioration cannot be assumed to imply protection from degeneration. (upenn.edu)
  • The ERG early shows loss of rod function and progression of the retinal disease subsequently leads to extinction of all rod and cone responses by midlife. (arizona.edu)
  • Symptoms of retinal vascular disease are sudden blurring or loss of vision in all or part of one eye. (foresthillsretina.com)
  • Retinal Macroglial Responses in Health and Disease. (ucm.es)
  • Analysis of Retinal Peripapillary Segmentation in Early Alzheimer's Disease Patients. (ucm.es)
Systemic1
  • Our results identify key molecular mechanisms involved such as imbalance between the stress Jun N-terminal kinase (JNK) and survival protein kinase B (PKB/Akt) pathways and increased systemic and retinal oxidative/inflammatory stress, resulting in increased retinal cell death and exacerbated acellular capillary formation. (molvis.org)
Progression1
  • Rate of Progression in EYS Related Retinal Degeneration (Pro-EYS). (wisc.edu)
Genes2
  • Retinal homeobox genes and the role of cell proliferation in cavefish eye degeneration. (ehu.eus)
  • We are comparing the expression patterns of various eye regulatory genes during surfacefish and cavefish development to determine the cause of eye degeneration. (ehu.eus)
Optical coherence3
  • We aimed to examine the extent to which measurement errors in the determination of retinal nerve fibre layer (RNFL) using spectral-domain optical coherence tomography (SD-OCT) occur in cases of epiretinal membrane and whether systematic deviations are found in the values obtained. (springer.com)
  • Lee DW, Kim JM, Park KH, Choi CY, Cho JG (2010) Effect of media opacity on retinal nerve fiber layer thickness measurements by optical coherence tomography. (springer.com)
  • Spectral domain optical coherence tomography imaging of the posterior segment of the eye in the retinal dysplasia and degeneration chicken, an animal model of inherited retinal degeneration. (omia.org)
Imbalance1
  • In conclusion, combining diabetes and hypertension-potentiated retinal oxidative/inflammatory stress promoted imbalance between the JNK stress and survival Akt pathways resulting in accelerated retinal cell death and acellular capillary formation. (molvis.org)
Microglia1
  • In the early stage of retinal degeneration, oxidative DNA damage accumulated in the microglia and caused single-strand breaks (SSBs) and poly(ADP-ribose) polymerase activation. (jci.org)
Tears2
  • Acute horseshoe retinal tears and traumatic breaks usually require treatment. (guidelinecentral.com)
  • Vitrectomy surgery is a more invasive procedure in which an incision is made in the eye to remove some of the vitreous humor and repair any retinal tears. (meghalayamagazine.in)
Damage3
  • Hypertension and diabetes are known risk factors for retinal microvascular damage. (molvis.org)
  • We found differences in white matter properties specific to OR white matter fascicles projecting to primary visual cortex locations corresponding to the location of retinal damage (fovea). (elsevierpure.com)
  • In sum, we demonstrate a specific relation between visual loss, anatomical location of retinal damage and white matter damage in AMD patients. (elsevierpure.com)
Disorder1
  • Frontotemporal dementia (FTD) is a neurodegenerative disorder characterised by degeneration within the frontal and temporal lobes of the brain [ 20 , 41 , 46 ]. (biomedcentral.com)
Patients3
  • Patients presenting with an acute PVD and no retinal breaks have a small chance (∼2%) of developing retinal breaks in the weeks that follow. (guidelinecentral.com)
  • Between 5% and 14% of patients found to have an initial retinal break will develop additional breaks during long-term follow-up. (guidelinecentral.com)
  • A meeting with low-vision/blind patients at FDA to share perspectives regarding their experience living with retinal degenerations in order to enrich the knowledge of CDRH staff involved in the review of these devices. (nih.gov)