• Our results add to the growing body of research in humans on the relationship between in utero exposure to OCs and reproductive outcomes. (cdc.gov)
  • Our results suggest that coffee consumption during pregnancy might not itself contribute to adverse outcomes such as stillbirth, sporadic miscarriages and pre-term birth or lower gestational age or birthweight of the offspring. (ntnu.no)
  • There is limited evidence on how the classification of maternal metabolic syndrome during pregnancy affects children's developmental outcomes and the possible mediators of this association. (biomedcentral.com)
  • This study uses a cohort sample of 12,644 to 13,832 mother-child pairs from the UK Born in Bradford Study to examine the associations between maternal metabolic syndrome classification (MetS) and child development outcomes at age 5, using cord blood markers as candidate mediators. (biomedcentral.com)
  • The results support the hypothesis that maternal metabolic syndrome classification during pregnancy is associated with some child developmental outcomes at age 5. (biomedcentral.com)
  • A health statistics review uses existing health data from data sources like birth certificates and health registries to determine whether health outcomes in a particular community are occurring at a higher, lower, or about the same level compared to statewide or national levels after taking into account factors such as gender and age of individuals within the community. (cdc.gov)
  • 1 , 3 Excess weight at the beginning of pregnancy and excess gestational weight gain (GWG) have been associated with adverse maternal and infant health outcomes such as a large for gestational age (LGA) infant, cesarean delivery, or preterm birth. (uspreventiveservicestaskforce.org)
  • The secondary outcomes included incidence of large for gestational age (LGA) babies as defined by birth weight greater than the 90th percentile as well as incidence of SGA and LGA in preterm and term gestations. (bvsalud.org)
  • In this study we investigated whether these joint introductions of tobacco control policies in the Netherlands were associated with changes in key perinatal outcomes known to be associated with maternal smoking and/or SHS exposure. (nature.com)
  • Some studies have identified relationships between PFAS exposure and reproductive outcomes, although the evidence regarding the pathway and significance of associations is mixed. (biomedcentral.com)
  • The unresolved "epidemiological paradox" concerns the association between low socioeconomic status and unexpectedly favourable birth outcomes in foreign born mothers. (bmj.com)
  • The "healthy migrant" effect concerns the association between foreign born status per se and birth outcomes. (bmj.com)
  • Background: Maternal sensitivity, or high quality maternal caregiving, in which the mother leads and structures the infant's early experiences in a responsive way, is associated with improved child development outcomes and health, both in the immediate and long term, and thus an important area of public health research. (columbia.edu)
  • Aim: This study investigates the association of several factors: (1) maternal depressive symptomology, (2) breastfeeding, (3) concurrent maternal alcohol intake and (4) infant biological vulnerability upon outcomes of (1) Maternal Sensitivity and (2) Infant Cognitive Development, as well as their effect on the association between senstivity and cognitive development. (columbia.edu)
  • Elevated levels of maternal cortisol have been hypothesized as the intermediate process between symptoms of depression and psychosocial stress during pregnancy and adverse birth outcomes. (researchsquare.com)
  • Therefore, we examined associations between cortisol levels in the second trimester of pregnancy and risks of three common birth outcomes in a nested case-control study. (researchsquare.com)
  • Multivariable linear and logistic regression was performed to assess the associations between continuous and categorized cortisol levels and the selected outcomes. (researchsquare.com)
  • The results of this study showed no suggestions of associations between maternal awakening cortisol levels in mid-pregnancy and adverse birth outcomes, except for an increased risk of SGA. (researchsquare.com)
  • Common adverse birth outcomes, including preterm birth, low birth weight, and small-for-gestational age (SGA), are associated with neonatal mortality and long-term health problems, including neurodevelopmental impairments, respiratory and gastrointestinal complications, and higher sympathetic activity, which is considered a risk factor for cardiovascular disease [1-4]. (researchsquare.com)
  • Previous research linked maternal psychosocial problems with increased risks of these birth outcomes, but the underlying mechanisms have not been fully understood yet [5]. (researchsquare.com)
  • Background: Variations in cardiovascular disease risk (CVD) are suggested to be partly influenced by factors that affect prenatal growth patterns and outcomes, namely degree of maternal investment (proxied by birth weight and gestational age). (zu.ac.ae)
  • However, the association between IPI and maternal and neonatal outcomes in women whose first delivery was by cesarean delivery is unclear. (biomedcentral.com)
  • The prevalence of obesity continues to rise and its direct association with multiple co-morbidities has substantial effect on disease outcomes and increased health care spending. (napcrg.org)
  • Interestingly, recent studies suggest that increasing paternal age (father's age) can also have affects on childhood mortality [4] and neurodevelopmental outcomes. (edu.au)
  • Eligibility criteria included having BP measurements from 20 weeks or more of gestation and evaluating the association between BP measurements and maternal or neonatal outcomes. (drugtopics.com)
  • Serious maternal complications, perinatal death, small-for-gestational-age infants, preterm birth, and neonatal intensive care unit (NICU) admission were the primary outcomes of the analysis. (drugtopics.com)
  • It has been reported that hydration of pregnant and breastfeeding women is linked with maternal or offspring health outcomes, which arouses awareness on TWI of women during pregnancy and lactation [ 5 ]. (springer.com)
  • Patterns of gestational weight gain and birthweight outcomes in the Eunice Kennedy Shriver National Institute of Child Health and Human Development Fetal Growth Studies-Singletons: a prospective study. (medstarauthors.org)
  • Objective To evaluate the breadth, validity, and presence of biases of the associations of vitamin D with diverse outcomes. (bmj.com)
  • Ten outcomes were examined by both meta-analyses of observational studies and meta-analyses of randomised controlled trials, but the direction of the effect and level of statistical significance was concordant only for birth weight (maternal vitamin D status or supplementation). (bmj.com)
  • Conclusions Despite a few hundred systematic reviews and meta-analyses, highly convincing evidence of a clear role of vitamin D does not exist for any outcome, but associations with a selection of outcomes are probable. (bmj.com)
  • Based on prior study results, our primary analyses focused on monoethyl phthalate (MEP) in relation to our outcomes of interest. (researcher-app.com)
  • In secondary analyses, most other phthalates were not found to be related to study outcomes, though some associations were noted. (researcher-app.com)
  • Given the prevalence of phthalate exposures and the growing evidence of associations with metabolic outcomes, future studies should continue to examine this question in diverse cohorts of pregnant women, particularly in those who may be at higher risk for GDM and IGT. (researcher-app.com)
  • An association between VOC-contaminated drinking water and adverse late pregnancy outcomes is plausible, but further investigation is needed. (cdc.gov)
  • The Brazil Ministry of Health (MoH) established a task force to investigate the possible association of microcephaly with Zika virus infection during pregnancy and a registry for incident microcephaly cases (head circumference ≥2 standard deviations [SD] below the mean for sex and gestational age at birth) and pregnancy outcomes among women suspected to have had Zika virus infection during pregnancy. (cdc.gov)
  • Further studies are needed to confirm the association of microcephaly with Zika virus infection during pregnancy and to understand any other adverse pregnancy outcomes associated with Zika virus infection. (cdc.gov)
  • As part of the China-Anhui Birth Cohort study, maternal sociodemographic characteristics, food intake, lifestyle, information on vitamin D supplementation, and birth outcomes were prospectively collected. (medscape.com)
  • We also examined associations between maternal serum OC levels and low birth weight, preterm delivery, and small for gestational age, but numbers were small. (cdc.gov)
  • This study aimed to determine if hypothyroidism prior to, or during, pregnancy increases the risk of attention-deficit hyperactivity disorder (ADHD) in the child and how the association may be modified by preterm birth, sex of the child, and race-ethnicity. (nih.gov)
  • Stratified analyses were used to evaluate whether the association is affected by timing of first diagnosis, gestational age at birth (term vs. preterm), sex, and race-ethnicity. (nih.gov)
  • Strength of the association was strongest in preterm born infants, boys, and Hispanic children. (nih.gov)
  • Although we cannot suggest causation , our results suggest that PAS, regardless of pathologic severity, is not associated with pathologic fetal growth in the preterm period. (bvsalud.org)
  • Primary outcome measures were: perinatal mortality, preterm birth and being small-for-gestational age (SGA). (nature.com)
  • We undertook a national quasi-experimental study, which involved analysing the association between the 2004 and 2008 joint introduction of tobacco control policies and perinatal mortality, preterm birth and SGA births using monthly data from a comprehensive dataset of singleton births in the Netherlands between 2000 and 2011. (nature.com)
  • We did not observe any associations between maternal cortisol levels and preterm birth and low birth weight. (researchsquare.com)
  • To assess whether there was an independent association between maternal 25-hydroxyvitamin D concentrations at 24-28 weeks of gestation and preterm birth in a multicenter U.S. cohort of twin pregnancies. (grassrootshealth.net)
  • A similar protective association was observed when studying preterm birth at less than 32 weeks of gestation (OR 0.2, 95% CI 0.1-0.6) and after confounder adjustment. (grassrootshealth.net)
  • Late second-trimester maternal 25-hydroxyvitamin D concentrations less than 75 nmol/L are associated with an increase in the risk of preterm birth in this cohort of twin pregnancies. (grassrootshealth.net)
  • Parental smoking during pregnancy and its association with low birth weight, small for gestational age, and preterm birth offspring: a birth cohort study. (precisionenvironmed.com)
  • Title : Association of Maternal Body Mass Index, Excessive Weight Gain, and Gestational Diabetes Mellitus With Large-for-Gestational-Age Births Personal Author(s) : Kim, Shin Y.;Sharma, Andrea J.;Sappenfield, William;Wilson, Hoyt G.;Salihu, Hamisu M. (cdc.gov)
  • The USPSTF has made recommendations on screening for obesity in adults, screening for gestational diabetes mellitus, and behavioral counseling interventions to promote a healthy diet and physical activity for cardiovascular disease prevention in adults with and without cardiovascular risk factors. (uspreventiveservicestaskforce.org)
  • 105 384 newborns (⩾2000 g and ⩾36 weeks) were analysed, and the effect of higher birth weight on total serum bilirubin (TSB) ⩾342 μmol/l was reported using logistic regression to control for gestational age, scalp injury diagnosis, maternal diabetes, method of delivery and other confounders. (bmj.com)
  • In-utero hyperglycemia exposure influences later cardiometabolic risk, although few studies include women with pre-existing type 2 diabetes (T2D) or assess maternal body mass index (BMI) as a potential confounder. (nature.com)
  • To explore the association of maternal T2D and gestational diabetes mellitus (GDM) with childhood anthropometry, and the influence of maternal BMI on these associations. (nature.com)
  • This study aimed to evaluate the impact of sleep quality and duration on gestational diabetes mellitus (GDM) occurrence. (healthandbehavior.com)
  • The primary aim of this study is to investigate the relationship between birth weight for gestational age and weight gain trajectories in early childhood and long term incidence of multiple chronic conditions including cardiometabolic disease risk factors (as Types 1 & 2 diabetes mellitus, hypertension, adult obesity, and hyperlipidemia), Asthma and Polycystic ovarian Syndrom. (napcrg.org)
  • The Cumulative Incidence of different chronic diseases in this cohort by age 30 year are as follows: Hypertension 3.1%, Hyperlipidemia 4.2%, Types 1&2 Diabetes: 1.9%, Asthma 18.0%, PCOS 2.4% (among 4839 females). (napcrg.org)
  • abstract = 'Abstract OBJECTIVE Intrauterine exposure to maternal type 1 diabetes is associated with a less favorable metabolic profile later in life. (ku.dk)
  • This study aimed to evaluate the effect of maternal pregestational type 1 diabetes on the presence of fatty liver in offspring and the association between maternal BMI, glycemic control during pregnancy, offspring metabolic risk factors, and offspring level of soluble CD163 (sCD163) (a marker of macrophage activation) and risk of fatty liver. (ku.dk)
  • RESULTS More type 1 diabetes-exposed offspring had high FLI and WHtR indices compared with unexposed control subjects. (ku.dk)
  • CONCLUSIONS Intrauterine exposure to maternal type 1 diabetes and higher maternal prepregnancy BMI may predispose to fatty liver in the offspring. (ku.dk)
  • We recently reported associations between fetal imprinted genes represented as an allele score and both gestational diabetes and maternal glucose concentrations in late pregnancy [ 6 ]. (biomedcentral.com)
  • We prospectively investigated refined-grain intake during pregnancy in association with offspring growth through age 7 y among high-risk children born to women with gestational diabetes mellitus (GDM). (fabresearch.org)
  • Gestational diabetes mellitus occurs with the onset of pregnancy and is characterized by the inability of the pregnant patient to tolerate glucose. (healthhyme.com)
  • Patients who develop gestational diabetes may develop diabetes later in life. (healthhyme.com)
  • However, gestational diabetes often resolves after delivery. (healthhyme.com)
  • The cause of gestational diabetes is largely unknown. (healthhyme.com)
  • According to the American Diabetes Association (2013), gestational diabetes affects 18% of pregnancies. (healthhyme.com)
  • Gestational diabetes often doesn't cause any symptoms. (healthhyme.com)
  • If women are at increased risk of gestational diabetes they will be offered a full test, which takes place during weeks 24-28 of pregnancy. (healthhyme.com)
  • Women may be screened for gestational diabetes at first antenatal appointment with doctor which takes place around weeks 8-12 of pregnancy. (healthhyme.com)
  • At this time, doctor will find out if women are at increased risk of gestational diabetes. (healthhyme.com)
  • They will ask about any known risk factors for gestational diabetes, such as whether they have a family history of diabetes. (healthhyme.com)
  • If women had gestational diabetes in a previous pregnancy, the GTT will be carried out at weeks 16-18 of pregnancy - or sooner, if indicated by the first blood glucose sample. (healthhyme.com)
  • Pregnant patients are routinely screened for gestational diabetes mellitus between 24 and 29 weeks' gestation. (healthhyme.com)
  • In order to diagnose gestational diabetes, patients drink 50 grams of oral glucose solution. (healthhyme.com)
  • Most patients with gestational diabetes are treated through diet. (healthhyme.com)
  • Patients with gestational diabetes should consume a diet that provides 30 kcal/kg/day. (healthhyme.com)
  • Furthermore, patients with a body mass index greater than 30 kg/m2 may benefit from a 30%-33% caloric restriction.Besides proper diet and exercise, some patients may require insulin or oral hypoglycemia agents to manage gestational diabetes mellitus. (healthhyme.com)
  • Resistance exercise can help overweight patients with gestational diabetes avoid insulin therapy. (healthhyme.com)
  • Most women with gestational diabetes go on to have normal pregnancies with healthy babies. (healthhyme.com)
  • The risk of complications is reduced if gestational diabetes is diagnosed and managed properly throughout pregnancy. (healthhyme.com)
  • Characterizing Gestational Weight Gain According to Institute of Medicine Guidelines in Women with Type 1 Diabetes Mellitus: Association with Maternal and Perinatal Outcome. (medstarauthors.org)
  • Fetal ovarian cysts have been associated with pregnancies complicated by maternal diabetes, toxemia, and Rh isoimmunization, probably due to the increased production of hCG by the placenta and are rarely associated with other congenital anomalies [2, 4, 6, 12-14]. (degruyter.com)
  • Phthalates are common plasticizer chemicals that have been linked to glucose intolerance in the general population, but there is only limited research on their association with gestational diabetes (GDM). (researcher-app.com)
  • However, there were no adverse associations between maternal serum OC levels and birthweight, length, head circumference or ponderal index. (cdc.gov)
  • gestational age and pre-term birth (N = 43 568 from the 23andMe, Inc cohort) and birthweight (N = 297 356 reporting own birthweight and N = 210 248 reporting offspring's birthweight from UKBB and the Early Growth Genetics Consortium). (ntnu.no)
  • Although both analyses showed an association between increased coffee consumption and higher birthweight, the magnitude of the effect was inconsistent. (ntnu.no)
  • The aim of the study is to evaluate whether pathologic severity of placenta accreta spectrum (PAS) is correlated with the incidence of small for gestational age (SGA) and neonatal birthweight . (bvsalud.org)
  • Data including maternal history , neonatal birthweight , and placental pathology were collected and deidentified. (bvsalud.org)
  • We also found that an estimated 26% of the association between maternal smoking and early-onset endometriosis could be explained by birthweight-for-gestational age. (lu.se)
  • Differences in risk factors for incident and recurrent small-for-gestational-age birthweight: a hospital-based cohort study. (medstarauthors.org)
  • Are maternal depression, breastfeeding, maternal alcohol intake and infant biological vulnerability effect modifiers or confounders of the maternal sensitivity and infant cognitive development association? (columbia.edu)
  • Although previous research has established that exposure to high maternal sensitivity advances the outcome of infant cognitive development, factors such as breastfeeding, which is hypothesized to confound the association, or depression, which is negatively associated with sensitivity, have not yet been examined together in a single study. (columbia.edu)
  • The majority of infant studies examining the maternal sensitivity-infant cognition association include either normal birth weight infants or LBW infant samples. (columbia.edu)
  • Univariate and multi-variable regression analyses were used to examine whether the four maternal factors were associated with Maternal Sensitivity, measured by the Nursing Child Assessment Teaching Scale (NCATS), and with Cognitive Development, measured by the Bayley Scale of Infant Development, Research Edition (BSF-R). (columbia.edu)
  • Conclusion: This research demonstrates that an independent association between maternal sensitivity and infant cognitive development remains even after adjusting for breastfeeding, and that breastfeeding is a separate means to advancing infant cognitive development. (columbia.edu)
  • Mental developmental index (MDI) and psychomotor developmental index (PDI) values were measured using the Korean version of the Bayley Scales of Infant Development II (K-BSID-II) at 24 months of age. (biomedcentral.com)
  • Several biological mechanisms have been proposed for linking elevated maternal cortisol levels to infant birth weight. (researchsquare.com)
  • Maternal smoking during pregnancy is an established risk factor for low infant birth weight, but evidence on critical exposure windows and timing of fetal growth restriction is limited. (plos.org)
  • Maternal smoking during pregnancy is an established risk factor for low infant birth weight. (plos.org)
  • No associations were observed between refined-grain intake and infant growth. (fabresearch.org)
  • The association between infant feeding pattern and mother's quality of life in Taiwan. (precisionenvironmed.com)
  • Effect of breastfeeding duration on infant growth until 18 months of age: a national birth cohort study. (precisionenvironmed.com)
  • Associations between infant developmental delays and secondhand smoke exposure modified by maternal pre-pregnancy overweight and obesity status. (precisionenvironmed.com)
  • We evaluated the association between 11 urinary phthalate metabolites and GDM, impaired glucose tolerance (IGT), and continuous blood glucose concentration during pregnancy in The Infant Development and Environment Study (TIDES). (researcher-app.com)
  • NCHS has just released a new report that presents preliminary data on births and birth rates and selected maternal and infant health characteristics for the United States in 2014. (cdc.gov)
  • The median gestational age of NICU infants was 36 weeks, median birth weight was 2.2 kg and 49.5% were delivered by non-elective caesarean section. (who.int)
  • Looking towards the regional and age differential in mortality, this paper attempts to provide evidence for the differential in mortality clustering among infants (aged 0-11 months), children (12-59 months) and under-five (0-59 months) period among mothers from the Empowered Action Group (EAG) and non-EAG regions of India. (biomedcentral.com)
  • There was no association for infants ⩾39 weeks. (bmj.com)
  • Further research should explore the causal mechanism for the association in less-mature infants. (bmj.com)
  • The marked increase in infants born with microcephaly in Brazil after a 2015 outbreak of Zika virus (Zika virus) disease suggests an association between maternal Zika virus infection and congenital microcephaly. (cdc.gov)
  • However, none of these studies examine the association between sensitivity and cognitive outcome in infants exclusively premature or SGA. (columbia.edu)
  • Palliation should be performed to allow infants to reach the age and weight requirements for correction. (medscape.com)
  • The results pointed positive correlations between anxiety and self-care, and negative associations between maternal stress and cognitive development of infants. (bvsalud.org)
  • The association with timing of the tobacco control policies was investigated using interrupted time series logistic regression analyses with adjustment for confounders. (nature.com)
  • Multilevel logistic regression was used to examine the interaction between maternal education and foreign born status, adjusting for covariates. (bmj.com)
  • The multivariate logistic regression analysis was performed to assess the independent association of sleep-related variables with GDM occurrence. (healthandbehavior.com)
  • We stratified analyses by pre-existing maternal medical conditions and pregnancy complications associated with increased ultrasound use (ultrasound indications) and used logistic regression to model case status by increasing ultrasound counts. (cdc.gov)
  • Multivariable logistic regression models, adjusted for genetic ancestry, were used to estimate associations between each GI-PGS and (1) ASD case-control status, and (2) specific GI symptoms in neurotypical children and separately in ASD children. (cdc.gov)
  • Odds ratios and 95% confidence intervals were calculated by logistic regression for the association between parental age and childhood cancer after adjustment for sex, birth weight, gestational age, birth order, plurality, maternal race, birth year, and state. (oregonstate.edu)
  • CONCLUSIONS: Our results suggest that older maternal age increases risk for most common childhood cancers. (oregonstate.edu)
  • On the basis of the available evidence, an association between vitamin D concentrations and birth weight, dental caries in children, maternal vitamin D concentrations at term, and parathyroid hormone concentrations in patients with chronic kidney disease requiring dialysis is probable, but further studies and better designed trials are needed to draw firmer conclusions. (bmj.com)
  • Results indicate that maternal prepregnancy severe obesity increases risk of ASD and DD in children and suggest high gestational-age-adjusted GWG is a risk factor for ASD in male children. (constantcontact.com)
  • The prevalence of overweight and obesity is increasing among persons of childbearing age and pregnant persons. (uspreventiveservicestaskforce.org)
  • Altered early growth likely influences the metabolic syndrome pathway, with obesity and T2D both occurring at a younger age [ 7 ]. (nature.com)
  • Pathogenesis of obesity is multifactorial but some risk factors have been associated with maternal health during pregnancy. (napcrg.org)
  • Our study combined multiple factors across a range of levels, and found that the associations of maternal cardiovascular health with offspring cardiovascular health were not driven by any one metric (such as obesity),' Perak added. (hcplive.com)
  • Higher maternal refined-grain intake during pregnancy was significantly related to a greater BMIZ and a higher risk of overweight or obesity at age 7 y among children born after pregnancies complicated by GDM. (fabresearch.org)
  • The author and colleagues examined the association between maternal smoking during pregnancy and fetal/childhood growth, specifically risk of childhood obesity, by using the dataset from an ongoing prospective cohort study called "Project Koshu," which enrolled pregnant women and their children from a rural area of Japan. (go.jp)
  • From the HAPO studies, investigators obtained disinformation related to maternal demographics, parity, and alcohol use through patient questionnaires. (hcplive.com)
  • Data collected included mother's age and ciencies exist in women of childbearing parity, infant's birth weight and gestation age [ 8,9 ]. (who.int)
  • Results: Median serum concentrations of several OCs (such as DDT, DDE and HCB) were much higher than U.S. averages reported by CDC. (cdc.gov)
  • We quantified urine cotinine concentrations in mothers once from 12th to 20th gestational weeks and excluded those whose urine cotinine levels exceeded 42.7 ng/ml to represent SHS exposure in early pregnancy. (biomedcentral.com)
  • Throughout pregnancy, maternal cortisol levels increase twofold, and cortisol crosses the placenta, accounting for 30-40% of the variability in fetal concentrations [10]. (researchsquare.com)
  • The statistical analysis revealed an association between higher gestational concentrations of monoethyl phthalate (mEP) and smaller total gray matter volumes in offspring at age 10. (neurosciencenews.com)
  • Higher maternal concentrations in urine during pregnancy of monoisobutyl phthalic acid (mIBP), a metabolite of diisobutyl phthalate (DIBP), were associated with smaller white matter only in girls. (neurosciencenews.com)
  • In 2020 and 2021, the Generation R Study reported that maternal prenatal urinary concentrations of phthalates were associated with lower non-verbal IQ at age 6 years. (neurosciencenews.com)
  • Previously we found that certain fetal imprinted genes represented as an allele score are associated with maternal pregnancy glucose concentrations. (biomedcentral.com)
  • Recently it was reported that fetal polymorphisms with strong associations with birth weight tend to mediate these independently of increases in maternal pregnancy glucose concentrations. (biomedcentral.com)
  • We therefore investigated whether potential associations between the fetal allele score and birth weight were related to maternal glucose concentrations in the Cambridge Baby Growth Study. (biomedcentral.com)
  • This association was partially attenuated by adjusting for maternal glucose concentrations (β = 50 (4-95) g/risk allele, β′ = 0.089, p = 0.03, n = 405). (biomedcentral.com)
  • The large for gestational age at birth association was also partially attenuated by maternal glucose concentrations. (biomedcentral.com)
  • Genetics can have roles in regulating both maternal glucose concentrations in pregnancy and fetal growth expressed as offspring birth weight. (biomedcentral.com)
  • However none of the fetal variants used to construct the gene score in this study were independently associated with maternal glucose concentrations. (biomedcentral.com)
  • In the current study we therefore examined relationships between our fetal imprinted gene allele score and measures of size at birth, in particular investigating whether any allele score associations with size at birth appear to be attenuated by maternal glucose concentrations in pregnancy. (biomedcentral.com)
  • Results 107 systematic literature reviews and 74 meta-analyses of observational studies of plasma vitamin D concentrations and 87 meta-analyses of randomised controlled trials of vitamin D supplementation were identified. (bmj.com)
  • The associations between vitamin D concentrations and various conditions and diseases have been assessed in a large and rapidly expanding literature. (bmj.com)
  • [ 5 , 6 ] It is noteworthy that fetal and newborn concentrations of 25(OH)D depend on and correlate with maternal serum levels. (medscape.com)
  • METHODS: This total-population register-based cohort study consisted of 628 312 singleton women born in Sweden between 1973 and 1987, who were followed for diagnosed endometriosis from age 15 years until the end of 2012. (lu.se)
  • Methods: Using data from the Early Childhood Longitudinal Study-Birth (ECLS-B) Cohort, a nationally representative sample of U.S. born children, depressive symptomology was evaluated as an effect-modifier, and breastfeeding was evaluated as a confounder of the sensitivity-cognitive development association. (columbia.edu)
  • METHODS: We used data from the Study to Explore Early Development, a multisite case-control study of preschool-aged children with ASD implemented during 2007-2012. (cdc.gov)
  • METHODS: We assessed the relationship between parental age and childhood cancer in a case-control study using pooled population-based data. (oregonstate.edu)
  • To help answer these questions, assessment of the timing of Zika virus transmission and its relation to gestational week of pregnancy for the cohort of women who were pregnant during the outbreak is necessary. (cdc.gov)
  • We explored the association between prenatal exposure to SHS and neurodevelopment at 24 months of age considering genetic polymorphism and breastfeeding in 720 mothers and their offspring enrolled in the Korean multicenter birth cohort study (Mothers and Children Environmental Health, MOCEH). (biomedcentral.com)
  • BACKGROUND: Studies evaluating the association between prenatal ultrasounds and autism spectrum disorder (ASD) have largely produced negative results. (cdc.gov)
  • OBJECTIVE: To evaluate the association between prenatal ultrasound use and ASD. (cdc.gov)
  • Using the life history trajectory model, this study investigates whether maternal investment in early prenatal life associates with menarcheal age and whether maternal investment affects CVD risk in adulthood and predicts adult size and adiposity levels. (zu.ac.ae)
  • A new study linked higher prenatal exposure to certain phthalates with reduced gray matter in children's brains by age 10. (neurosciencenews.com)
  • Additionally, prenatal exposure resulted in decreased white matter volumes in female children. (neurosciencenews.com)
  • Multivariable Cox regression was applied to examine associations with perinatal. (lu.se)
  • Through reducing maternal smoking and SHS exposure, tobacco control policies have considerable potential to benefit perinatal health. (nature.com)
  • However, we can confirm previous findings of perinatal determinants as high maternal pre-pregnancy BMI, and smoking during pregnancy being risk factors for childhood overweight. (nih.gov)
  • Results from a recent study indicated that lowering the threshold for abnormal blood pressure in the second half of pregnancy from 140/90 mm Hg would not increase accuracy in identifying maternal or perinatal risk in patients. (drugtopics.com)
  • Risk for cesarean section was increased in association with induction of labor in cases of high maternal weight (OR 10.3, CI 16.0 - 67.0), and somewhat of high birth weight (OR 2.3, but CI containing 1). (scirp.org)
  • Conclusion: Although the results do not fully support that Emirati females fast-life history is associated with increased chronic disease risk, the data does suggest a link between restricted fetal growth in response to low maternal investment and metabolic and reproductive health. (zu.ac.ae)
  • Both the two-sample MR and one-sample GRS analyses showed no change in risk of sporadic miscarriages, stillbirths, pre-term birth or effect on gestational age connected to coffee consumption. (ntnu.no)
  • Univariate regression analyses showed that of the measures of biological vulnerability, premature birth had the greatest association with both sensitivity and cognitive development in comparison to the LBW or SGA. (columbia.edu)
  • Trimester-specific analyses using medical record data showed no association in any individual trimester. (cdc.gov)
  • Regression analyses were conducted to establish associations. (zu.ac.ae)
  • We compared results from (1) confounder-adjusted multivariable analyses, (2) a Mendelian randomization (MR) analysis using maternal rs1051730 genotype as an instrument for smoking quantity and ease of quitting, and (3) a negative control analysis comparing maternal and mother's partner's smoking associations. (plos.org)
  • Study limitations include measurement error due to maternal self-report of smoking and the modest sample size for MR analyses resulting in unconfounded estimates being less precise. (plos.org)
  • In fully-adjusted models, which accounted for birth factors including preeclampsia, did not fully explain significant associations observed in the other analyses. (hcplive.com)
  • Sensitivity analyses indicated possible strong race-specific associations in Asians, though these results are based on a small sample size (n = 35). (researcher-app.com)
  • The Society of Obstetricians and Gynecologists of Canada (SOGC) released revised guidelines that simplified the classification of hypertension in pregnancy into four categories, pre-existing hypertension, gestational hypertension, preeclampsia, or "other hypertensive effects" on the basis of different diagnostic considerations. (medscape.com)
  • After adjusting for maternal, child, and environmental covariates, maternal metabolic syndrome classification during pregnancy was associated with children's LIT domain through direct effects of maternal metabolic health and indirect effects of cord blood markers (total effects), and COM and PSE domains via changes only in a child's cord blood markers (total indirect effects). (biomedcentral.com)
  • ABSTRACT Micronutrient deficiencies exist among women of childbearing age in the United Arab Emir- ates but the effects of maternal micronutrient deficiency on fetal growth are not well documented. (who.int)
  • However, the effect of maternal vitamin D supplementation on fetal growth has not been confirmed. (medscape.com)
  • Gestational choriocarcinoma can happen during and after any type of pregnancy event, though risk of the disease is higher in and after complete or partial molar pregnancies. (wikipedia.org)
  • Risk of disease may also be higher in those experiencing pregnancy at younger or older ages that average, such as below 15 years old or above 45 years old. (wikipedia.org)
  • Depending on the risk of gestational trophoblastic disease (GTD) development, such as in certain people with mole pregnancies, chemotherapy has been used in a preventative manner in the past. (wikipedia.org)
  • The study consisted of 326,991 children and found that cumulative exposure to aluminum from vaccines during the first two years of life was associated with a small increased risk of persistent asthma in children ages 2-5 years. (cdc.gov)
  • Lower gestational age, lower birth weight, delivery by caesarean section and birth in the month of May were statistically significant risk factors for NICU admission. (who.int)
  • Incidence rate differences (IRDs), adjusted hazard ratios (aHRs), and their 95% confidence intervals (CIs) were estimated to evaluate the association of maternal hypothyroidism with childhood ADHD risk. (nih.gov)
  • Exposure to maternal hypothyroidism during the periconceptual period significantly increases the risk of ADHD and that the association varies with gestational age at delivery, child sex, and race-ethnicity. (nih.gov)
  • Maternal hypothyroidism increases the risk of ADHD diagnosis in the offspring. (nih.gov)
  • A health statistics review can take risk factors such as age, race and sex that are commonly found on health records into account. (cdc.gov)
  • Death clustering refers to the unusual concentration of mortality in certain families, which occurs due to a positive association of the risk of mortality among the siblings of those families [ 5 ]. (biomedcentral.com)
  • We investigated the associations of maternal and birth characteristics with risk of endometriosis among Swedish women of reproductive age. (lu.se)
  • With expanding local Zika virus transmission and the possible link between Zika virus infection during pregnancy and congenital microcephaly, projecting the effects of Zika virus infections for other countries and understanding the gestational time when risk is greatest are critical. (cdc.gov)
  • This risk is significantly influenced by maternal weight, birth weight and Bishop score. (scirp.org)
  • We aimed to investigate the association between IPI after cesarean delivery and the risk of maternal and neonatal adverse events. (biomedcentral.com)
  • Maternal postpartum distress is apparently not an independent risk factor for childhood overweight at 7-years-of-age. (nih.gov)
  • Based on final results we will be concluding whether birth weight status and/or elevated BMI trajectory persisting from birth through childhood and adolescence result in an unfavorable cardiometabolic risk profile in during that time and through adulthood. (napcrg.org)
  • We found significant associations between increasing maternal prepregnancy BMI, being born large for gestational age, offspring level of sCD163, as well as offspring metabolic risk factors (decreasing adiponectin and HDL cholesterol and increasing leptin, HOMA of insulin resistance, and HOMA of insulin secretion) and degree of fatty liver. (ku.dk)
  • The table below shows the correlation of maternal age (mother's age) and the potential risk of human genetic abnormalities in children. (edu.au)
  • Advanced maternal age and risk of non-chromosomal anomalies: data from a tertiary referral hospital in Turkey [8] "The purpose of this study is to determine if there is a relationship between non-chromosomal fetal anomalies of various organ systems and advanced maternal age. (edu.au)
  • Although there is lack of tenable evidence to support the positive effect of increased water intake on milk production, substantial water loss via milk puts women at a high risk of dehydration, which lays an adverse effect on maternal health [ 11 ]. (springer.com)
  • Parental age and risk of childhood cancer: a pooled analysis. (oregonstate.edu)
  • We investigated whether advancing parental age increases childhood cancer risk. (oregonstate.edu)
  • Working hours and risk of gestational hypertension and pre-eclampsia. (precisionenvironmed.com)
  • We discuss about risk factors for the development of the baby, especially main measurements maternal and sociodemographic. (bvsalud.org)
  • Interpregnancy interval (IPI) has been linked with several maternal and neonatal adverse events in the general population. (biomedcentral.com)
  • BACKGROUND: Arsenic, a common groundwater pollutant, is associated with adverse reproductive health but few studies have examined its effect on maternal health. (oregonstate.edu)
  • Using data from the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study and HAPO Follow-up study, Perak and a team of colleagues from Northwestern and Lurie Children's Hospital designed their study with the hope of assessing how maternal cardiovascular health during pregnancy might be associated with offspring cardiovascular health in adolescence. (hcplive.com)
  • Furthermore, many previous studies had small sample sizes and limited data on covariates, possibly resulting in residual confounding. (researchsquare.com)
  • [ 1 ] Maternal morbidity and mortality are also increased in pregnancies complicated by multiple gestations and multiple births. (medscape.com)
  • [ 7 ] Hypertensive disorders in pregnancy may cause maternal and fetal morbidity, and they remain a leading source of maternal mortality. (medscape.com)
  • These results suggest that associations between the fetal imprinted gene allele score and size at birth are mediated through both glucose-dependent and glucose-independent mechanisms. (biomedcentral.com)
  • The authors of this study concluded that for any level of maternal glucose concentration fetal genetics has a major impact on growth but acts predominantly through mechanisms independent of maternal glucose. (biomedcentral.com)
  • For their offspring, investigators assessed cardiovascular health using 4 metrics: BMI, blood pressure, total cholesterol levels, and glucose level, which were assessed between the ages of 10-14 years. (hcplive.com)
  • As a result, the pregnant patient is unable to process glucose in the body and hyperglycemia occurs. (healthhyme.com)
  • Additional phthalate metabolites were also found to be linked to glucose intolerance, with possible stronger associations in certain racial/ethnic subgroups. (researcher-app.com)
  • Mediation models were used to examine the associations between the classification of maternal metabolic syndrome and child developmental milestones. (biomedcentral.com)
  • Association of a good sleep quality and adequate nocturnal sleep duration with metabolic health has been reported in several epidemiological studies. (healthandbehavior.com)
  • Models were adjusted for potential maternal, socioeconomic, and child confounders such as maternal education, deprivation, and gestational age. (biomedcentral.com)
  • Maternal alcohol use and biological vulnerability were also hypothesized to be confounders of the sensitivity-cognitive association. (columbia.edu)
  • Adjustment for potential confounders did not alter the results. (nih.gov)
  • Triplet pregnancies result from various fertilization, splitting, and development scenarios that involve ova and sperm. (medscape.com)
  • For pregnancies with medical record data on ultrasound timing, we conducted supplementary tests to model associations by trimester of exposure. (cdc.gov)
  • However, stratified regression models showed no association between increasing ultrasound counts and case status, either for pregnancies without (aOR 1.01, 95% CI 0.92, 1.11) or with ultrasound indications (aOR 1.01, 95% CI 0.95, 1.08). (cdc.gov)
  • Women (aged ≥ 18 years) whose first delivery was cesarean delivery with 2 consecutive singleton pregnancies from the National Vital Statistics System (NVSS) database between 2017 and 2019 were included in this retrospective cohort study. (biomedcentral.com)
  • [ 7 , 21-23 ] The controversial findings may be due to variations of study designs, including the gestational weeks, dose, season, and adherence of maternal vitamin D supplementation as well as ethnicity of the study population. (medscape.com)
  • However, scarce literature is present to capture this unusual concentration of mortality in certain families by examining the association of the mortality risks among the siblings of those families along with various unobserved characteristics of the mother. (biomedcentral.com)
  • Mortality clustering occurred among specific families in Brazil and was a result of shared familial characteristics among the siblings of the same family [ 13 ]. (biomedcentral.com)
  • Unobserved genetic characteristics shared by siblings of the same parent resulted in mortality clustering among Guatemalan children [ 10 ]. (biomedcentral.com)
  • A general linear model was used to assess the relationship between maternal urinary cotinine level and neurodevelopment. (biomedcentral.com)
  • Multivariable regression was performed to assess BMI and age as predictors for UDFF.Twenty-two participants were male, 24 were female, and the mean age was 14 ± 3 (range: 7-18) years. (stanford.edu)
  • We analysed data from 8,621 white European liveborn singletons from 2 population-based pregnancy cohorts to assess the associations of maternal quitting, reducing, and continuing smoking during pregnancy with the longitudinal growth of different fetal parameters (weight, head circumference, femur length, and abdominal circumference). (plos.org)
  • Primary outcome is impairment-free survival at 18-22 months corrected age. (stanford.edu)
  • Outcome was childhood overweight at 7-years-of age. (nih.gov)
  • No obvious predictors for maternal events or child outcome were determined, except for a possible relation between severe pulmonary regurgitation and symptomatic heart failure. (bmj.com)
  • Maternal micronutrient status affects preg- supplements are routinely prescribed for nancy outcome [ 1,2 ] and maternal micro- the obstetric population, but compliance is nutrient deficiency has been reported to be generally poor. (who.int)
  • A consistent linear dose-dependent association of maternal smoking with fetal growth was observed from the early second trimester onwards, while no major growth deficit was found in women who quit smoking early in pregnancy except for a shorter FL during late gestation. (plos.org)
  • Birthrates of dizygotic twins vary by race (10-40 per 1000 births in blacks, 7-10 per 1000 births in whites, and approximately 3 per 1000 births in Asians) and maternal age (ie, the frequency has risen with increasing maternal age ≤40 years). (medscape.com)
  • Cord blood levels of 25-hydroxyvitamin D [25(OH)D], calcium, and phosphorus were measured in 1491 neonates who were divided into three groups based on the duration of maternal vitamin D supplementation during pregnancy. (medscape.com)
  • There is limited evidence from human studies on how maternal cardiometabolic health during pregnancy affects a child's cognitive and behavioural development. (biomedcentral.com)
  • It is useful not only for diagnosis but also for monitoring disease progression, treatment response, and potential of recurring gestational choriocarcinoma. (wikipedia.org)
  • The association of maternal hypothyroidism with childhood ADHD was influenced by timing of diagnosis. (nih.gov)
  • RESULTS: During follow-up, 8262 women received an endometriosis diagnosis. (lu.se)
  • We investigated associations between maternal postpartum distress covering anxiety, depression and stress and childhood overweight. (nih.gov)
  • The overweight/obese children grew faster than did the non-overweight children in the early pubertal stages, and the non-overweight children caught up and showed greater height gains at older ages. (go.jp)
  • This observational study suggests a possible association between exposure to aluminum in some childhood vaccines and development of persistent asthma in children. (cdc.gov)
  • Maternal exposure to SHS during pregnancy may result in delayed MDI in early childhood. (biomedcentral.com)
  • Childhood Brain Development: Is There a Critical Window for Maternal TSH Measurement? (obgproject.com)
  • One study had shown the positive association of maternal education and household wealth status with the mortality clustering in families in a historical Italian population [ 14 ]. (biomedcentral.com)
  • Chronic hypertension (HTN) is determined by this threshold being met before 20 weeks of gestation, while HTN is gestational when met at 20 weeks or more of gestation. (drugtopics.com)
  • Gestational hypertension (transient hypertension of pregnancy or chronic hypertension identified in the latter half of pregnancy). (medscape.com)
  • Greater maternal antenatal BMI was associated with increased anthropometric measures in offspring independent of maternal glycemic status. (nature.com)
  • The American College of Cardiology (ACC) and American Heart Association (AHA) recommended lowering BP thresholds for HTN in 2017 to 120/80 mm Hg or more, but these recommendations have not been used in pregnancy HTN guidelines. (drugtopics.com)
  • Average birth weight and average gestational age were statistically significantly lower in the highly exposed population than in the control area prior to filtration of municipal water supply. (biomedcentral.com)
  • When investigating the associations of birth weight SDS and age at menarche with growth indices, it was found that only birth weight was positively and significantly associated with both height (β = 1.342 cm, 95% CI (0.12, 2.57), p = 0.032) and leg length (β = 0.968 cm, 95% CI (0.08, 1.86), p = 0.034). (zu.ac.ae)
  • The findings from China suggest that maternal vitamin D supplementation recommended by the IOM results in a slight but significantly higher fetal level of 25(OH)D and improves fetal growth. (medscape.com)
  • The etiology of fetal ovarian cysts is still unknown, although a linkage with fetal gonadotrophin stimulation derived from maternal estrogens or placental human chorionic gonadotrophin (hCG) has been suggested. (degruyter.com)
  • Associations with trajectories of estimated fetal weight (EFW) and individual fetal parameters (head circumference, femur length [FL], and abdominal circumference [AC]) from 12-16 to 40 weeks' gestation were analysed using multilevel fractional polynomial models. (plos.org)
  • Association of in utero organochlorine pesticide exposure and fetal growth and length of gestation in an agricultur al population. (cdc.gov)
  • An analysis of more than 2000 mother-child pairs indicates maternal cardiovascular health at 28 weeks' gestation, which was assessed based on BMI, blood pressure, and other factors, can help predict offspring cardiovascular health between 10-14 years age. (hcplive.com)
  • During gestation, plasma volume experiences a physical expansion, and amniotic fluid from maternal body fluids maintains and protects the development of fetus. (springer.com)
  • Adjustment for maternal BMI strengthened the negative association between GDM and child weight, BMI and circumferences. (nature.com)
  • Maternal T2D was no longer associated with greater child mean skinfolds ( p = 0.14) or waist circumference ( p = 0.18) after adjustment for maternal BMI. (nature.com)
  • Linear and Poisson regressions were used, with adjustment for maternal demographic, lifestyle, and dietary factors. (fabresearch.org)