• The iterative design and additive 3D printing of the scaffolds allowed for rapid cycles of experiments and performance improvement, said Gazzola and co-first author Xiaotian Zhang, a postdoctoral researcher in Gazzola's lab. (nanowerk.com)
  • The group is comprised of a diverse array of clinicians, researchers, and clinician-researchers across the student, postdoctoral scholar/clinical trainee, and faculty/practitioner levels. (adaa.org)
  • The sensors could give surgeons real-time feedback on how much force they can use during surgery without damaging the tissue," said Kaiyan Qiu, a University of Minnesota mechanical engineering postdoctoral researcher and lead author of the paper. (newswise.com)
  • Dr Vishal Bhavsar , postdoctoral researcher with the Section of Women's Mental Health at the Department of Health Services and Population Research and Consultant Psychiatrist at South London and the Maudsley NHS Foundation Trust, has been awarded a National Institute for Health and Care Research (NIHR) Advanced Fellowship. (kcl.ac.uk)
  • Thereafter, she worked as a postdoctoral researcher at both the Department of Chemistry of the University of Saskatchewan (Canada) between 1989 and 1990, and the Department of Chemistry of Queen's University in Kingston (Canada) between 1993 and 1994. (tcd.ie)
  • Claude Robert Cloninger (born April 4, 1944) is an American psychiatrist and geneticist noted for his research on the biological, psychological, social, and spiritual foundation of both mental health and mental illness. (wikipedia.org)
  • Our research vision is to develop and transform ocean modeling and data assimilation to quantify regional ocean dynamics on multiple scales. (mit.edu)
  • Microsatellites are molecular markers with numerous applications in biological research. (phys.org)
  • Currently working on RNA modeling projects at Max Planck Medical Research. (foresight.org)
  • The Edward J. Meeman Biological Station is the department's primary field research and teaching venue for ecology, environmental biology, and natural history. (memphis.edu)
  • With professional staff and equipment enabling research and training for students, postdocs, and researchers in micro-fabrication and surface characterization, this facility significantly enhances the University's capabilities and competitiveness in the targeted growth area of interdisciplinary materials science. (memphis.edu)
  • This SIG aims to facilitate increased attention on topics and issues concerning diversity and multiculturalism within ADAA and in the field in general, and encourages discussion, collaboration, and research among researchers, clinicians, and stakeholders interested in meeting the mental health needs of diverse underserved communities. (adaa.org)
  • The focus of the meeting is to explore new and existing uses of common ontologies to support sharing and discovery of data and resources, researcher networking, and particularly to support the evaluation of research. (bioontology.org)
  • Dr Monica Aas, researcher at the Social, Genetic and Developmental Psychology (SGDP) Centre, has received the UKRI Medical Research Council (MRC) Career Development Award, set up to improve human health by supporting world-class medical research. (kcl.ac.uk)
  • The £918k grant will fund Dr Aas's research into the integration of psychological models and biological pathways in psychosis. (kcl.ac.uk)
  • This research strongly suggests that biological ageing plays an important role in causing coronary artery disease, the commonest cause of death in the world. (medindia.net)
  • The Vanderbilt engineers have two decades of research experience in foundations of model-based design, design automation, AI assisted design processes and simulation of cyber-physical and human-cyber-physical systems. (vanderbilt.edu)
  • Additionally, she has held positions as Director of the Medicinal Chemistry Moderatorship, member of the Fellowship Central committee, Head of Organic, Medicinal and Biological Chemistry at the School of Chemistry, Director of Postgraduate Teaching and Learning, Director of Research and Director of Global Relationships at the School of Chemistry, Director of Dublin Chemistry postgraduate program, Tutor and served in numerous College committees and selection panels. (tcd.ie)
  • The results, from an exhaustive study of all births in California during the 1990s by UC Davis Health System researchers, are published online today in the February issue of the journal Autism Research. (livescience.com)
  • In research appearing in the Proceedings of the National Academy of Sciences , Daniel Forger and Charles Peskin explain their mathematical model of the biological clock that replicates the hundreds of clock-related molecular reactions that occur within each mammalian cell. (scienceagogo.com)
  • Additional research is needed to develop better tools for toxicity analysis, exposure-response modeling, and physiologically based pharmacokinetic and pharmacodynamic (PB/PK and PB/PD) modeling. (cdc.gov)
  • 3. Conduct research to better understand the toxicology (biological mechanisms) of mixed exposures. (cdc.gov)
  • The research activities of the CSB revolve around three major biophysical approaches for studying the structure and dynamics of complex biological macromolecules: NMR spectroscopy, X-ray crystallography, and electron cryo-microscopy. (stonybrook.edu)
  • Fundamental biological research often fails to include drug discovery, which is one of the most important and beneficial scientific contributions to mankind. (stonybrook.edu)
  • Most previous research focused on oral exposures (i.e., drinking water), but researchers are now finding that skin (dermal) contact may also be relevant. (cdc.gov)
  • The article, by researchers from the International Agency for Research on Cancer (IARC) and partners, was published today in the Journal of Virology . (who.int)
  • Our research group works on constructing and refining computational models to describe genetic, epigenetic and metabolic networks. (lu.se)
  • This interdisciplinary research is conducted in close collaboration with researchers in medicine and biology. (lu.se)
  • Methods: Using a community-based participatory research approach, community researchers administered a community-developed survey to 489 residents of Greater Lawndale who reported current or recent employment in a job that met at least one characteristic of precarious employment (e.g. unpredictable schedule, insecure work, no living wage/benefits). (cdc.gov)
  • The researchers used computational modeling to optimize the eBiobot design and component integration for robustness, speed and maneuverability. (nanowerk.com)
  • We describe a computational methodology allowing to systematically and quantitatively characterize a Boolean mathematical model of a biological network in terms of genetic interactions between all loss of function and gain of function mutations with respect to all model phenotypes or outputs. (researchgate.net)
  • In addition, we suggest several computational tools for studying the distribution of double mutants in the space of model phenotype probabilities. (researchgate.net)
  • Spectroscopic or computational work on metalloenzymes, or pure biochemical, biological, or biomedical studies on inorganic compounds are only encouraged if they clearly relate to specific properties of the metals or metalloid elements involved, and significantly further our understanding of inorganic chemistry. (rsc.org)
  • We welcome studies that report new models of reactivity, selectivity, bonding or structure, or new computational methods, that have relevance for the design of subsequent experiments. (rsc.org)
  • Some of us use computational modeling to understand how proteins fold and how proteins bind to proteins and design drugs for high-affinity binding to proteins. (stonybrook.edu)
  • Qualitative and quantitative models are built for both physiological background and most important physiological and molecular players in selected medical problems. (oru.se)
  • The overarching goal of the SD-NSC Human Cell Models of Aging Core is to create and make available powerful, new human cell-based models to enable studies into the molecular and cellular heterogeneity of human aging. (salk.edu)
  • Bioinformatics provides the tools to understand complex biological systems ranging from entire ecological systems to specific human diseases, to cellular and molecular networks. (memphis.edu)
  • We include the extensive use of molecular methods in this field and the use of models to understand and predict disease outbreaks. (usda.gov)
  • At the core of far-from-equilibrium biological activity lies an orchestra of molecular motors, constantly dissipating energy while converting chemical fuel into mechanical work. (europa.eu)
  • I will incorporate the nanotube sensors in minimal biomimetic models of active systems, including DNA-gel and reconstituted cytoskeleton driven by molecular motors, to demonstrate my approach in a highly controlled environment. (europa.eu)
  • They also found that without the inherent randomness of molecular interactions within a cell, biological rhythms may dampen over time. (scienceagogo.com)
  • Their model was validated with a large library of data on the concentrations of the molecular species within the mouse molecular clock at different times of the day and data on the behavior of mice with circadian clock mutations. (scienceagogo.com)
  • Without the rapidity of molecular interactions within these cells, the precision of the biological clock would be lost. (scienceagogo.com)
  • Laufer Center researchers come from a broad community including Stony Brook departments of chemistry, physics, applied mathematics and statistics, computer science, molecular genetics and microbiology as well as Cold Spring Harbor Laboratory. (stonybrook.edu)
  • Our groups is multidisciplinary including clinical PhD students and clinical researchers along with a biostatistician, molecular biologist and technical personnel. (lu.se)
  • Advances in quantification of biology and medicine will soon render obsolete researchers and practitioners who are not fluent in quantitative assessment of data and mechanistic understanding of biological and medical systems through modeling and simulation. (confex.com)
  • A key goal is rapid, targeted intervention and selection of a depression treatment with the highest likelihood of working for an individual patient based on their specific biology, through the development of an explanatory and predictive end-to-end model. (vanderbilt.edu)
  • In a biological modeling process whose goal is the incremental conversion of observations to knowledge, models will evolve by formulating alternative biology-based model structures and evaluating them with new observations, Sztipanovits said. (vanderbilt.edu)
  • We believe a promising approach to address model selection is a biology-guided learning process that represents existing but partial knowledge symbolically and complements it with machine learning-based components such as deep neural networks for completing the alternative models," said Sztipanovits. (vanderbilt.edu)
  • We will extend our DeepForge design studio with new components for supporting Biology-Guided Learning in the modeling process and make it available for the program," said Sztipanovits. (vanderbilt.edu)
  • To accelerate the creation of new models spanning different science disciplines, Vanderbilt will incorporate state-of-the-art data platforms from another society-scale biology challenge: predicting pandemics. (vanderbilt.edu)
  • besides, she has driven the foundation of the Division of Medicinal and Biological Chemistry within the Institute of Chemistry of Ireland (ICI) and its adherence to the European Federation of Medicinal Chemistry and Chemical Biology (EFMC) in 2022. (tcd.ie)
  • Organoid cell culture has transformed cell-based assays in drug discovery and basic biology by conferring physiologic relevance to in vitro cell-based biological models. (corning.com)
  • The researchers were jointly led by Maksim Plikus, an assistant professor of developmental and cell biology, and Qing Nie, a professor of mathematics, both of UCI. (medicalnewstoday.com)
  • Model organisms such as yeast, fruit flies, and worms have advanced the study of genomics, eukaryotic biology, and evolution. (cshlpress.com)
  • Such systems biology models can, for example, describe how whole populations interact with their environment, how individual cells choose to differentiate into different cell types, or how multicellular systems form patterns and grow new organs in two or three dimensions. (lu.se)
  • We spent our time at the Marine Biological Laboratory in Woods Hole, Massachusetts. (edu.au)
  • Hirsh and his team, which includes doctoral student Rozi Andretic and technician Sarah Chaney, use fruit flies as their genetic models for humans. (sciencedaily.com)
  • During the late 70s, Cloninger worked on modeling complex patterns of inheritance using path analysis to allow for both genetic and cultural inheritance. (wikipedia.org)
  • He worked to develop methods for disentangling genetic, cultural, and other environmental influences on mental disorders until he concluded that such statistical modeling would never convince skeptics or provide precise estimates when biological parents also reared their own children. (wikipedia.org)
  • Genetic interaction can be defined as a deviation of the phenotypic quantitative effect of a double gene mutation from the effect predicted from single mutations using a simple (e.g., multiplicative or linear additive) statistical model. (researchgate.net)
  • Experimentally characterized genetic interaction networks in model organisms provide important insights into relationships between different biological functions. (researchgate.net)
  • We demonstrate this methodology on three published models for each of which we derive the genetic interaction networks and analyze their properties. (researchgate.net)
  • Genome-wide association study of handedness excludes simple genetic models. (medlineplus.gov)
  • Multilocus genetic models of handedness closely resemble single-locus models in explaining family data and are compatible with genome-wide association studies. (medlineplus.gov)
  • Genetic deletion of Kif11 in hepatocytes inhibited the development of HCC in a mouse model. (bvsalud.org)
  • In perspective, we aim to use qualitative modeling together with biosignature screening for synergistic effects: Better quality biosignatures, with relevant predictive values in the clinical setting, are expected by including knowledge about how clinical and physiological variables work together. (oru.se)
  • He identified and described heritable personality traits predictive of vulnerability to alcoholism and other mental disorders in prospective studies of adoptees reared apart from their biological parents. (wikipedia.org)
  • In this project I hope to trace the biological underpinnings of childhood trauma to enable us to develop predictive models and preventative strategies for psychosis, hopefully leading to improved treatment options in the future. (kcl.ac.uk)
  • Our team is also an Early Access Partner for Microsoft's Premonition technology, which is an industrial platform for predicting pandemics by integrating diverse biological data sets and performing cloud-scale predictive analytics and machine learning," said Sztipanovits. (vanderbilt.edu)
  • Neema said the team will leverage both data-driven and knowledge-centric approaches to build new hybrid neuro-symbolic models that provide causative and predictive understanding of complex biological systems. (vanderbilt.edu)
  • 3D modeling is more predictive of biological systems, making in vitro results more easily translated to human patients. (corning.com)
  • Many challenges present themselves when creating realistic cellular models, from the detailed spatial representation of membranes and organelles to convoluted biochemical pathways. (psc.edu)
  • 3D models better represent the physical and biochemical environments that viruses encounter in vivo . (corning.com)
  • The consensus that graduate programs in the biological, medical, and health sciences should include quantitative skills in the training of researchers, clinicians, and health care deliverers has yet to coalesce on statistical and mathematical content, use of software, and ways to integrate with existing curricula and expertise. (confex.com)
  • They are continuing these studies and using statistical models to understand the interactions between different solutes and develop rational methods to select the proper combination of molecules to stabilize cells. (umn.edu)
  • Experience: Bridge the gap between experimental scientists and statistical researchers by representing the causal mechanisms that are likely to lead to biological damage of policy interest. (cdc.gov)
  • The use of this methodology for validating mathematical models from experimental data and designing new experiments is discussed. (researchgate.net)
  • R 0 is affected by numerous biological, sociobehavioral, and environmental factors that govern pathogen transmission and, therefore, is usually estimated with various types of complex mathematical models, which make R 0 easily misrepresented, misinterpreted, and misapplied. (cdc.gov)
  • Although R 0 is a biological reality, this value is usually estimated with complex mathematical models developed using various sets of assumptions. (cdc.gov)
  • The principles can then be converted into mathematical models. (lu.se)
  • Our new mathematical model predicted details of signaling communications between hairs, otherwise difficult to reveal with standard biological experiments alone," says Prof. Nie. (medicalnewstoday.com)
  • Together we develop new models and methods for new types of experiments and data. (lu.se)
  • The results of these experiments are used to develop biological principles for how insects control their flight using their vision and how they avoid obstacles. (lu.se)
  • We have used an iterative approach with MCell simulations and synaptic physiology to refine our mammalian model of the neuromuscular active zone. (psc.edu)
  • New York University researchers have developed a model of the intra-cellular mammalian biological clock that reveals how the rapid interaction of molecules with DNA produces reliable 24-hour rhythms. (scienceagogo.com)
  • therefore the flies can be used as a tool to study the complex biological processes underlying drug abuse. (sciencedaily.com)
  • Improvements in computer resources and the interests of an increasing number of researchers have allowed TEM to evolve over time to better examine the influence of ecosystem processes and human activities on terrestrial biogeochemistry and how changes in this biogeochemistry may feedback to influence atmospheric chemistry, climate, water quantity and quality, and social welfare. (mbl.edu)
  • The model resembles some key elements of an embryo at around 18-21 days old and allows the researchers to observe the processes underlying the formation of the human body plan never directly observed before. (scitechdaily.com)
  • This is a hugely exciting new model system, which will allow us to reveal and probe the processes of early human embryonic development in the lab for the first time. (scitechdaily.com)
  • The key objective of the EU-funded NanoNonEq project is to tackle conceptual challenges associated with the measurement of the stochastic dynamics of such biological processes. (europa.eu)
  • Estimating the amount of the free energy budget lost to dissipation is crucial for a deeper understanding of the underlying nonequilibrium dynamics and for unravelling the thermodynamic constraints on the possible biological processes. (europa.eu)
  • Biological applications include the study of decomposition processes in soil where fungi interact with organic molecules and mineral particles. (lu.se)
  • Scientists from the University of Cambridge, in collaboration with the Hubrecht Institute in The Netherlands, have developed a new model to study an early stage of human development using human embryonic stem cells. (scitechdaily.com)
  • Model organisms including mice and zebrafish have previously enabled scientists to gain some insights into human gastrulation. (scitechdaily.com)
  • Scientists at USC have created a mathematical model that explains and predicts the biological process that creates antibody diversity - the phenomenon that keeps us healthy by generating robust immune systems through hypermutation. (phys.org)
  • The organ models we are 3D printing are almost a perfect replica in terms of the look and feel of an individual's organ, using our custom-built 3D printers," said lead researcher Michael McAlpine, an associate professor of mechanical engineering in the University of Minnesota's College of Science and Engineering and a 2017 recipient of the Presidential Early Career Award for Scientists and Engineers (PECASE). (newswise.com)
  • For the first time, scientists engineered a mouse model of "baldness" in an attempt to understand how poor hair growth occurs in humans. (medicalnewstoday.com)
  • Researchers must expand these methods to include PFAS that are relevant to workplace exposures. (cdc.gov)
  • We modeled the association between employment precarity and occupational exposures using logistic regression models. (cdc.gov)
  • Genetics researchers have long been able to manipulate genes in fruit flies for investigations of nervous system pathways. (sciencedaily.com)
  • By manipulating these pathways, researchers may, in the future, not only be able to stimulate hair growth, but also stop hair from growing in undesired areas. (medicalnewstoday.com)
  • Integrating microelectronics allows the merger of the biological world and the electronics world, both with many advantages of their own, to now produce these electronic biobots and machines that could be useful for many medical, sensing and environmental applications in the future," said study co-leader Rashid Bashir, an Illinois professor of bioengineering and dean of the Grainger College of Engineering. (nanowerk.com)
  • Remotely controlled miniature biological robots have many potential applications in medicine, sensing and environmental monitoring. (nanowerk.com)
  • This project will investigate the biological and environmental underpinnings of psychosis, including the role of stress in mental health, to help develop preventative strategies. (kcl.ac.uk)
  • We then apply these advances to better understand physical, acoustical and biological interactions. (mit.edu)
  • Newly designed microfluidic device enables researchers to observe plant root-microbe interactions in real time. (anl.gov)
  • The interpretation of R 0 estimates derived from different models requires an understanding of the models' structures, inputs, and interactions. (cdc.gov)
  • Bashir's group has pioneered the development of biobots, small biological robots powered by mouse muscle tissue grown on a soft 3D-printed polymer skeleton. (nanowerk.com)
  • The eBiobots are the first wireless bio-hybrid machines, combining biological tissue, microelectronics and 3D-printed soft polymers. (nanowerk.com)
  • Drive technology development to create novel organoid and hybrid-cell models to investigate the role of cellular heterogeneity in human tissue and organ aging. (salk.edu)
  • Researchers tested the tissue and developed customized silicone-based inks that can be "tuned" to precisely match the mechanical properties of each patient's prostate tissue. (newswise.com)
  • This article presents information on human lung tissue modeling as a platform for studying COVID-19. (corning.com)
  • In our process these materials serve as the bioinks, substances made of sugars and proteins that can be used for 3D printing of complex tissue models," Prof. Dvir says. (scienceblog.com)
  • Structural data required for building spatially realistic cell models, and even larger connectomics models, are particularly demanding of both resolution and spatial extent. (psc.edu)
  • New approaches are needed to economically handle these speeds and data scales and make the resulting datasets available for long term on-demand analyses by researchers and students nationwide. (psc.edu)
  • Furthermore, the various TEM subgroups have developed input data sets, collaborated with other groups in the development of other ecosystem models, and participated in model intercomparisons to examine how differences in model assumptions may influence simulated ecosystem responses to natural and human disturbances. (mbl.edu)
  • Our group creates and utilizes new models and methods for multiscale modeling, uncertainty quantification, data assimilation and the guidance of autonomous vehicles. (mit.edu)
  • All specimen data are published online and continually updated, and are freely available to researchers everywhere. (memphis.edu)
  • Through the use of machine learning (ML) algorithms and big data, health care professionals can provide next-level patient care, and researchers can speed up their work considerably. (forbes.com)
  • While there is a long way to go before any clinical application, there are data in experimental models where lengthening telomere length has been shown to retard and in some situations reverse age-related changes in several organs. (medindia.net)
  • Using a combination of mathematical modeling and biological data, the researchers were able to map hair growth patterns across the entire skin. (medicalnewstoday.com)
  • For example, researchers should develop the ability to use data from proteomics and genomics studies and extrapolate these to whole body systems. (cdc.gov)
  • The prediction models integrate patient´s, clinical and tumour related data to achieve high accuracy. (lu.se)
  • Advanced modeling and simulations allow researchers to quickly experiment with different biological variables, giving them the flexibility they need. (forbes.com)
  • The alternative models that reflect different biological hypotheses may have different knowledge gaps that will impact model selection decisions. (vanderbilt.edu)
  • This makes direct-induction protocols particularly well-suited for creating cellular models of human aging. (salk.edu)
  • The advancement of 3D cell culture disease modeling has allowed researchers to study viral and cellular science more realistically than ever before. (corning.com)
  • RESULTS: We established a cellular senescence-related genes-based stratified model, and a multivariable-based nomogram, which could accurately predict the prognosis of CC patients in the TCGA database. (bvsalud.org)
  • The integration of electronic sensors or biological neurons would allow the eBiobots to sense and respond to toxins in the environment, biomarkers for disease and more possibilities, the researchers said. (nanowerk.com)
  • Creates a place for clinicians and researchers to discuss, debate, and address issues relevant to the understanding and treatment of childhood anxiety and mood disorders. (adaa.org)
  • The SIG promotes networking between clinicians and researchers and helps combat isolation for therapists in private practice and offers opportunities for learning and connection between the annual conferences through online communication and CE. (adaa.org)
  • For this reason it is important to develop better models of human development. (scitechdaily.com)
  • By looking at which genes were expressed in these human gastruloids at 72 hours of development, the researchers found a clear signature of the event that gives rise to important body structures such as thoracic muscles, bone, and cartilage, but they do not develop brain cells. (scitechdaily.com)
  • Vanderbilt researchers have been selected by Wellcome Leap as one of 12 global teams to develop an integrated model of depression and to identify biologically effective treatment in an accelerated timeframe. (vanderbilt.edu)
  • To identify which children would develop autism, the researchers obtained electronic records identifying children born during the study period who later received an autism diagnosis from state Department of Developmental Services. (livescience.com)
  • Researchers will develop fluorescent nanosensors that will allow them to detect the microscopic activity of motor proteins. (europa.eu)
  • In my lab, I will develop fluorescent nanosensors for unveiling microscopic activity otherwise inaccessible in complex biological systems. (europa.eu)
  • Researchers are also expanding how they study the collected serum to include more PFAS compounds as they become available for evaluation and to develop ways to collect air samples in workplace settings. (cdc.gov)
  • We develop and analyse models of biological networks to improve our understanding of how living cells and tissues function. (lu.se)
  • Based on these models, other researchers can develop small, light control systems for uses such as in drones. (lu.se)
  • Findings: The primary clinical classifier model had an area under receiver operating characteristic curve (AUC) of 0·92 (95% CI 0·90-0·95) in EARLI and 0·88 (0·84-0·91) in VALID. (lu.se)
  • A new review article summarizes epidemiological and biological findings that support the existence of a novel model of human papillomavirus (HPV)-mediated carcinogenesis. (who.int)
  • These nanosensors will be functionalised for use in biomimetic models of biological systems and live cells to infer quantitative information on dissipation. (europa.eu)
  • A team of researchers led by the University of Minnesota has 3D printed lifelike artificial organ models that mimic the exact anatomical structure, mechanical properties, and look and feel of real organs. (newswise.com)
  • A team of researchers from the University of California, Irvine (UCI) set out to explore hair growth across the skin surface of the entire body. (medicalnewstoday.com)
  • The design allows for possible future integration of additional microelectronics, such as chemical and biological sensors, or 3D-printed scaffold parts for functions like pushing or transporting things that the biobots encounter, said co-first author Youngdeok Kim, who completed the work as a graduate student at Illinois. (nanowerk.com)
  • Increases in relative employment precarity were significantly associated with self-reported exposure to chemical and biological hazards, physical hazards, and slip, trip, strike, fall, trap or crush hazards at work. (cdc.gov)
  • R 0 is rarely measured directly, and modeled R 0 values are dependent on model structures and assumptions. (cdc.gov)
  • Trees survive Minnesota winters using combinations of molecules expressed naturally to stabilize critical biological structures. (umn.edu)
  • The Terrestrial Ecosystem Model (TEM) is a process-based ecosystem model that describes carbon, nitrogen and water dynamics of plants and soils for terrestrial ecosystems of the globe. (mbl.edu)
  • It also regards the family as more than just the sum of the individual members, using models based on systems approach, such as used in cybernetics or game theory . (newworldencyclopedia.org)
  • The National Institutes of Health will fund six projects to identify biological factors that affect neural regeneration in the retina. (nih.gov)
  • The text allows biological control researchers and practitioners to leverage the ecological information provided to enhance sustainable pest management systems. (usda.gov)
  • We explore how protein motions cause biological mechanisms and how proteins aggregate in neurodegenerative diseases such as Parkinson's and Alzheimer's. (stonybrook.edu)
  • MCell is designed for studying just such systems, allowing researchers to run realistic simulations with arbitrarily complex 3D geometry, tracking the movement of discrete molecules as they diffuse and react with other molecules. (psc.edu)
  • With the popularity of these more complex models growing, we have assembled a team of experts to answer your questions on disease modeling using ALI tools and systems. (corning.com)
  • Speciation and separation studies that are primarily based around kinetic and thermodynamic models are not considered suitable for Dalton Transactions . (rsc.org)
  • From expert panel discussions on advances in 3D cell culture technique to perspectives on organoid applications to tried and true methods for specialized 3D model applications, Corning is pleased to offer the new e-book, Expert Guide to 3D Cell Culture, now available for download. (corning.com)
  • Researchers developed the current methods to study serum samples for PFAS based on what they know about how the general public is exposed. (cdc.gov)
  • Methods: In this observational, multicohort, retrospective study, we validated two machine-learning clinical classifier models for assigning ARDS subphenotypes in two observational cohorts of. (lu.se)
  • The hybrid "eBiobots" are the first to combine soft materials, living muscle and microelectronics, said researchers at the University of Illinois Urbana-Champaign, Northwestern University and collaborating institutions. (nanowerk.com)
  • Multidisciplinary scientist with a PhD in Biological Design from Arizona State University. (foresight.org)
  • It provides expertise in the use of microscopy to students, faculty and researchers at the University of Memphis and throughout the immediate area. (memphis.edu)
  • These unique inks were used in a custom-built 3D printer by researchers at the University of Minnesota. (newswise.com)
  • The risk of developing age-related diseases, such as multiple sclerosis, heart disease and cancer, has been linked with faster 'biological' aging in an international study led by researchers at the University of Leicester. (medindia.net)
  • Janos Sztipanovits, E. Bronson Ingram Distinguished Professor of Engineering and director of the Institute for Software Integrated Systems at Vanderbilt University, is principal investigator on the team's Modeling and Model Integration project. (vanderbilt.edu)
  • In a major medical breakthrough, Tel Aviv University researchers have "printed" the world's first 3D vascularised engineered heart using a patient's own cells and biological materials. (scienceblog.com)
  • An important resource for any model organism is a near-complete reference genome from which a multitude of scientific questions can be answered. (cshlpress.com)
  • A new study published in Science indicates that cocaine sensitization -- which is linked to addiction -- might be associated with circadian genes, the genes that set the biological clock. (sciencedaily.com)
  • In the first case study, we observed that the real biological networks were most sensitive to overexpression/state-flip and edge-addition/-reverse mutations among node-based and edgetic mutations, respectively. (researchgate.net)
  • Researchers use advanced technology and mice to study dopamine neuron structure, addiction and the brain's ability to recover. (anl.gov)
  • Researchers recently reported a technique that increases the regenerative capacity of retinal axons in a mouse model of optic nerve injury, a model commonly used to study glaucoma and other optic neuropathies. (nih.gov)
  • Laufer Center researchers insert gene circuits into cells and study noise. (stonybrook.edu)
  • From each study, researchers extracted outcome point estimates and corresponding 95% CIs, number of events in each group, and covariates included in the model. (medscape.com)
  • Aim: The present study seeks to investigate the profile and scientific production of Brazilian researchers in dentistry from the National Council for Scientific and Technological Development (CNPq). (bvsalud.org)
  • Conclusion: The results of this study reveal both a significant contribution from dentistry researchers towards the consolidation of national scientific production as well as the updating of information regarding dentistry production. (bvsalud.org)
  • Theoretical models and resources are now available - for example Ian Hacking's "looping effect" and Sally Haslanger's "discursive constructions" - that provide principled grounds for understanding social categories as both independently real and as the products of contingent social histories. (degruyter.com)
  • Modeling each type of molecule separately helped avoid mathematical assumptions in their model that may not be valid in real-life cells. (scienceagogo.com)
  • The researchers say the biggest task in the coming decade will be to optimize and broadly implement strategies that use human genetics to enhance understanding of health and disease, and maximize the benefits of treatment. (eurekalert.org)
  • We welcome work on model compounds of metalloenzymes and biologically active inorganic compounds, including reports on their synthesis, characterization and studies of their applications. (rsc.org)
  • These patient-specific organ models, which include integrated soft sensors, can be used for practice surgeries to improve surgical outcomes in thousands of patients worldwide. (newswise.com)
  • The researchers then attached soft, 3D printed sensors to the organ models and observed the reaction of the model prostates during compression tests and the application of various surgical tools. (newswise.com)
  • n=2813), a multinational, observational ARDS cohort, we applied a custom classifier model (with fewer variables than the primary model) to determine the prognostic value of the subphenotypes and tested their interaction with the positive end-expiratory pressure (PEEP) strategy, with 90-day mortality as the dependent variable. (lu.se)
  • Autism is a pervasive developmental disorder of deficits in social skills and communication, as well as repetitive and restricted behaviors, with onset occurring prior to age 3, the researchers explain in a statement. (livescience.com)
  • Our aim is to improve prediction models for regional and distant metastatic spread in breast cancer in order to individualise treatment selection for the individual patients. (lu.se)
  • One prediction model aims to preoperatively identify node-negative breast cancer patients for whom axillary surgery could be abstained. (lu.se)
  • Prediction of lymph node metastasis in breast cancer by gene expression and clinicopathological models: Development and validation within a population based cohort. (lu.se)
  • Create induced cell models that maintain age-related phenotypes. (salk.edu)
  • Application of these models can provide valuable prognostic information and could inform management strategies for personalised treatment, including application of PEEP, once prospectively validated. (lu.se)
  • Differentially expressed genes (DEGs) of senescence related genes between tumor and normal tissues were used for Least absolute shrinkage and selection operator (LASSO) regression to construct a prognostic model. (bvsalud.org)
  • application of these biological insights to drive new treatment and preventive options. (eurekalert.org)
  • Argonne National Laboratory has developed computer models to predict how disease can spread. (anl.gov)
  • The impacts of biological and clinical variables are considered in order to predict the evolution of certain diseases or health complications. (forbes.com)
  • Distribute protocols and key reagents relevant for creating induced cell types and organoid models. (salk.edu)
  • Discover how Dr. Hans Clevers from the Hubrecth Organoid Technology (HUB), located in Utrecth, The Netherlands, successfully expanded adult stem cell-derived organoids in genetically stable form and ultimately, was able to generate in vitro models of any epithelial disease from any patient. (corning.com)
  • Generate a bank of fibroblasts and corresponding induced pluripotent stem cells (iPSCs) that represent the breadth of healthy adult chronological age from a human cohort extensively phenotyped for key physical and functional measures of biological age. (salk.edu)
  • The models are mainly based on the interaction between different genes and proteins, for example in stem cells. (lu.se)
  • She worked as a researcher in the Medicinal Chemistry Institute (CSIC) until the year 2000, thereafter joining the School of Chemistry in TCD as a Lecturer. (tcd.ie)
  • There have been many in silico studies based on a Boolean network model to investigate network sensitivity against gene or interaction mutations. (researchgate.net)
  • Bumblebees use 'optical flow' to avoid colliding with their surroundings", explains Christine Scholtyssek, a researcher in the Vision Group. (lu.se)
  • Recently, we were focusing on investigating the role of butyrate in modeling the inflammatory response of gut epithelial cells, studying the switch-like behaviour of this system. (oru.se)
  • To facilitate bedside identification of subphenotypes, clinical classifier models using readily available clinical variables have been described in four randomised controlled trials. (lu.se)
  • Interpretation: Classifier models using clinical variables alone can accurately assign ARDS subphenotypes in observational cohorts. (lu.se)
  • Our environment is collaborative within a lively group of students and researchers. (mit.edu)
  • Marie Dacke and Emily Baird from the Vision Group collaborate with researchers at the Swiss Federal Institute of Technology, Lausanne, in the development of aerial robots. (lu.se)
  • However, these models may behave differently from human embryos when the cells start to differentiate. (scitechdaily.com)
  • Animal models can respond differently to certain drugs: the anti-morning sickness drug thalidomide, for example, passed clinical trials after testing in mice but subsequently led to severe birth defects in humans. (scitechdaily.com)
  • They also tested an underlying biological theory that threat and deprivation ACEs may manifest differently in neurodevelopment, with distinct impacts on primary headaches. (medscape.com)