Research projects approaches genomics. Medical search. Frequent questions

This talk will discuss how bioethics scholarship should approach issues related to the use of genetics and genomics in precision public health and the appropriate implementation of these technologies. (cdc.gov)
He applies genetics and genomics approaches to study age-related neurodegeneration associated with Alzheimer's disease, dementia and glaucoma. (jax.org)
Part of the Diana Davis Spencer Foundation's gift provides graduate students and postdoctoral fellows the opportunity to be mentored by world-class experts in ocular biology, genetics and genomics, disease modeling and computational biology. (jax.org)
It also stands nearly alone in that it requires all 600 of its nurses to undergo competency training in genetics and genomics. (genomeweb.com)
Every registered nurse at the largest clinical research hospital in the US must take a one-day course in the basics of genetics and genomics in healthcare, then score at least 80 percent in a post-course assessment exam. (genomeweb.com)
With the advent of precision medicine, a feeling amongst the leaders was that our nurses would be at the bedside, taking care of patients, all of whom are on research protocols at the Clinical Center, [and] that we [nurses] would be a place that patients might likely go to ask questions about genetics and genomics," NIH Clinical Center Chief Nurse Officer Gwenyth Wallen said. (genomeweb.com)
In the post-course assessment, nurses are rated on metrics including their understanding of the relationship of genetics and genomics to health, prevention, screening, and diagnostics, and the ability to put together a family health history and patient genetic pedigree from this family history information. (genomeweb.com)
Wallen noted that Calzone and Jenkins have worked extensively with nursing leaders at universities and Magnet -recognized hospitals on genetics and genomics competency programs. (genomeweb.com)
Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. (genomeweb.com)
More Dr. Chander received her PhD in Genetics and Genomics from the Human Genome Sequencing Center at Baylor College of Medicine under the mentorship of Dr. Richard Gibbs. (stanford.edu)
Realizing the benefits of human genetics and genomics research for people everywhere. (ashg.org)
Some are in the early stages of their career, while others are seasoned researchers who have experienced firsthand the enormous changes in genetics and genomics that have occurred over a relatively short period of time. (ashg.org)

The Medical Genomics Group has broad interests in the genomics and epigenomics of phenotypic plasticity in health and disease. (ucl.ac.uk)
He has made important contributions to the field of descriptive, functional and clinical genomics, epigenomics, and miRNA function. (tigem.it)
The Epigenomics and Mechanisms Branch's (EGM's) results to date indicate that the MUTSPEC 2.0 project can generate important knowledge on carcinogen properties. (who.int)

As discussed in chapter 10, the here developed semantic systems biology workflows were successfully applied in the discovery of key elements in symbiotic relationships, to improve functional genome annotation and in comparative genomics studies. (wur.nl)
JAX Professor Martin Pera , an expert in human stem cell biology, will also utilize the gifts for vision research. (jax.org)
The successful candidate will join CIGENE , a multidisciplinary genome biology research group possessing expertise in genetics, evolutionary and comparative genomics, bioinformatics and systems biology. (fems-microbiology.org)
The group wishes to use functional genomics technologies, including gene editing, to better understand the biology underlying specific genotype-phenotype associations. (fems-microbiology.org)
the successful candidate will also participate actively in teaching functional genomics and genome biology at the Faculty of Biosciences. (fems-microbiology.org)
PhD degree in functional genomics, molecular biology, cell biology, or similar obtained within the last 5 years, allowing for any parental leaves. (fems-microbiology.org)
The investments are being made through Genome Canada's 2015 Bioinformatics and Computational Biology Competition, a partnership with the Canadian Institutes of Health Research. (newswire.ca)
The Government of Canada is pleased to support these important bioinformatics and computational biology projects that will maximize the return on investment in genomics research. (newswire.ca)
Bioinformatics and Computational Biology is a priority area for Genome Canada given the growing need for enhanced tools and methodologies to make sense of the huge and growing influx of data stemming from genomics research. (newswire.ca)
Advances in bioinformatics and computational biology are providing scientists with innovative strategies for dealing with the vast amounts of information generated by genomics and extended 'omic' research. (newswire.ca)
Novel antibiotic drug discovery employing bacterial functional genomics, chemical genomics, biochemistry, molecular biology, microbial genetics and physiology approaches. (calstatela.edu)
Davide Cacchiarelli Associate Investigator Other positions: "Rita-Levi Montalcini" Associate Professor of Molecular Biology - Department of Translational Medicine, University of Naples "Federico II" "Armenise-Harvard" Principal Investigator of the Laboratory of Integrative Genomics Davide Cacchiarelli obtained a Master's Degree and a Doctorate Degree in Genetics and Molecular Biology from University of Rome "La Sapienza", working on mechanisms of RNA regulation. (tigem.it)
In 2011, he moved to The Broad Institute of MIT and Harvard and The Department of Stem Cell and Regenerative Biology at Harvard University to focus his research on the rules governing cell fate transitions and reprogramming using genomic approaches. (tigem.it)
Cacchiarelli's research leverages an interdisciplinary approach that brings together pluripotency and stem cell biology with cellular engineering, molecular diagnostics, genomic approaches and mathematical modeling. (tigem.it)
My research currently focuses on the evolution of the flowering gene network in Arabidopsis and soybean, taking an interdisciplinary approach encompassing molecular genetics, genomics, biochemistry, population genetics and systems biology, with an ultimate goal of plant improvement for higher adaptation to diverse and changing environments. (csun.edu)
Research areas Through programs spanning genetics, biology, and therapeutic development, Broad researchers are making discoveries that drive biomedical science forward. (broadinstitute.org)
Before joining the Broad Institute, he received his PhD in statistics from the University of Nottingham, and was a postdoctoral research fellow at Harvard School of Public Health and in the Department of Ecology and Evolutionary Biology at Princeton University. (broadinstitute.org)
NEW YORK (GenomeWeb News) - Three US research teams have reeled in $4.9 million in funding from the National Institutes of Health to use genomics and systems biology approaches to delve into the molecular basis of Alzheimer's disease. (genomeweb.com)
The omics and systems biology projects will receive a total of $4.9 million in fiscal year 2013, which ends in less than two weeks, but each of them could receive significantly more over the five years of their projects. (genomeweb.com)
At Mount Sinai, Eric Schadt, director of the Icahn Institute for Genomics and Multiscale Biology, will lead an effort to build models of biological networks based on molecular, cellular, and clinical data that will be used to study Alzheimer's and identify therapeutic targets. (genomeweb.com)
They plan to use a systems biology approach to integrate and analyze genomic, gene expression, and pathological data from Alzheimer's patients and mouse models. (genomeweb.com)
My projects integrate a broad range of approaches (e.g. quantitative physiology, genomics, cell biology) and of techniques either from our own section (e.g. molecular biology toolbox, cultivation in bioreactors, transcriptome analysis, fluorescence microscopy, FACS, etc.) or in collaboration (e.g. proteomic, metabolomics). (tudelft.nl)
Her current research focus is on the biology of depression and depression recovery, as well identifying effective strategies to improve mental and physical well-being. (stanford.edu)
However, the primacy of genomics as an explanatory or even causal approach to biology and medicine has been fundamentally limiting. (simonsfoundation.org)
In this lecture, Isaac Kohane will illustrate how a knowledgeable and deep embrace of dialectic between genomics and phenomenology is needed to rapidly advance our understanding of human biology and accelerate clinical medicine. (simonsfoundation.org)
EMBL is Europe's life sciences laboratory - an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology. (embl.org)
We examine the role of miRNAs in nodule development using a number of different approaches including genetics, genomics, molecular and cellular biology and microscopy. (sdstate.edu)
Research in the Jez lab uses a combination of structural biology, protein chemistry, and plant science to understand biochemical pathways in plants and microbes with the aim of engineering these systems to address agricultural and environmental problems. (isbr.info)
Focus areas are computer-designed programmable life forms like Xenobots and biobots, synthetic biology including genome recoding and organoid research, and organ-on-chip translational research that aims to bridge the gap between lab-based human model systems studies and human clinical trials. (isbr.info)
Dr Andrew Newhouse has been working on projects that overlap the fields of conservation biology and molecular biology since 2003. (isbr.info)
This Funding Opportunity Announcement (FOA) encourages applications for short-term mentored career enhancement (K18) awards in dental, oral and craniofacial (DOC) research with a focus on behavioral and social sciences, and on genetics, genomics, bioinformatics and computational biology research. (nih.gov)
We believe that similar evolutionary and systems biology approaches could further inform future biomedical research strategies and bring quite novel and unexpected perspectives on the distal causes of human diseases. (irb.hr)
Proposed project represents up to date joint efforts in evolutionary genetics of the Ruđer Bošković Institute, Zagreb and the Max-Planck-Institute for Evolutionary Biology, Plön and will allow knowledge and technology transfer in Croatia. (irb.hr)
This project offers a unique opportunity to delve into the dynamics of genetic variation and its implications for conservation biology, providing valuable contributions to the field and paving the way for future research in biodiversity conservation. (lu.se)
The Genetic and Molecular Epidemiology (GAME) research group is striving to understand how individual biology impacts the results of lifestyle changes. (lu.se)

In chapter 5, we introduced how the concept of protein domains and corresponding architectures can be used in comparative functional genomics to provide for a fast, efficient and scalable alternative to sequence-based methods. (wur.nl)
1) Using a comparative genomics approach, assess the genome differences between Lso haplotypes that induce ZC symptoms in potato and those that are only asymptomatic in potato upon infection. (usda.gov)
Sequencing results will be further incorporated into comparative genomics and phylogenetic analyses (approaches in Objective 1) to correlate genotypic data with our phenotypic knowledge. (usda.gov)
Abby has worked on comparative genomics projects of many different bacteria, including analyses of whole genome sequences of M. tuberculosis , Enterococcus , Fusobacterium , E. coli , and other microbes, with particular emphasis on the evolution of drug resistance and virulence factors. (broadinstitute.org)
She is currently using comparative genomics and transcriptomics to identify bacterial and host factors that govern Salmonella persistence. (broadinstitute.org)
She is interested in comparative genomics using pan-genome graphs. (broadinstitute.org)
I employ a range of meta-omics approaches including: meta-barcoding of microbiomes to assess microbial diversity coupled with the use of comparative meta-genomics and meta-transcriptomics in the frame of interdisciplinary and integrated research projects to link structural and functional diversity of microbes with diversity and community composition of plant communities. (ufz.de)
Our approach was to produce gene predictions by algorithms that rely on comparative sequence data but do not require direct cDNA evidence, then to test predicted novel genes by RT-PCR. (nih.gov)
Our results demonstrate that many important genes and gene fragments have been missed by traditional approaches to gene discovery but can be identified by their evolutionary signatures using comparative sequence data. (nih.gov)
This research program will combine studies of candidate genes with large-scale gene expression analysis, several mapping approaches and comparative genomics to study the genetic basis of trait evolution in wild bird populations. (europa.eu)
Third, we will identify the targets for adaptive evolution during avian evolution using comparative genomics. (europa.eu)

Now I am really fascinated by the methods and approaches which study cells holistically such as proteomics, genomics and metabolomics. (uni-goettingen.de)
Rapid developments in many biomedical disciplines, including genomics, proteomics, and bioinformatics, mean that scientists are faced with overwhelming amounts of new data, increasingly complex data types, evolving standards, and incompatible analytical tools. (the-scientist.com)
The ELLIPSS project will utilize the host of -omics tools and technologies (for proteomics, metabolomics, and genomics, for instance) that are making it increasingly possible to dissect the heterogeneity of single diseases and achieve more precision with treatments. (medscape.com)

The Department of Animal- and Aquacultural Sciences (IHA), Faculty of Biosciences, at the Norwegian University of Life Sciences (NMBU) is inviting applications for a 6-year tenure track position within functional genomics in aqua- and agri- research. (fems-microbiology.org)
Dr. Xu spent seven years at the biotechnology industry, engaging in discovery of novel antibiotics employing functional genomics, microbial physiology, assay development and high throughput screening approaches. (calstatela.edu)
He develops and applies computational techniques to address disease at multiple scales - from whole healthcare systems as "living laboratories" to the functional genomics of neurodevelopment with a focus on autism. (simonsfoundation.org)
Research topic: Construct soil metagenomic libraries from forest and grassland soils along land use gradients and screen for fungal functional genes. (ufz.de)
Another NIH-funded study, Utilizing In Vitro Functional Genomics Advances for Gene-Environment (GxE) Discovery and Validation , aims to better understand the connection between environmental exposure and human disease. (medlineplus.gov)

The study of deleterious variation, or genetic load, in natural populations has become increasingly important in conservation genomics, particularly with the advent of novel bioinformatics tools (see our related work in Bertorelle et al. (lu.se)

Profile: We are seeking a student with a strong background in bioinformatics, coupled with a keen interest and a solid understanding of population genetics and evolutionary genomics. (lu.se)

In September 2022, Apollo became an Assistant Staff in the Cleveland Clinic Lerner Research Institute. (ccf.org)
In 2022, the project announced that 100,000 highly diverse genome sequences have been completed, with 50% from racial or ethnic groups that have been historically underrepresented. (ashg.org)

As the application of evolutionary theory in biomedical research has proven to have substantial explanatory potential, it is tempting to test this novel approach on biomedical data. (irb.hr)
Within the scope of the proposed project we plan to explore, using phylostratigraphic approach, relationship among evolutionary age of the genes, full ontogenetic timing of their expression and their disease status. (irb.hr)

The Jackson Laboratory recently received $2 million in philanthropic gifts from The Gordon and Llura Gund Foundation trustee Gordon Gund, who is co-founder, director, and chairman emeritus of the Foundation Fighting Blindness , and an anonymous donor in support of vision research at the Laboratory. (jax.org)
We are profoundly grateful to the Diana Davis Spencer Foundation, Gordon Gund and an anonymous donor for this transformational gift in continued support of vision research at JAX," says Lon Cardon , Ph.D., FMedSci, president and CEO of The Jackson Laboratory. (jax.org)
He returned to Italy in 2017 thanks to the Armenise Harvard Foundation Career Development Award and now he leads the Laboratory of Integrative Genomics at TIGEM and coordinates a research group focused on understanding the dynamics of cell fate decisions, funded by an ERC-StG. (tigem.it)

We are planning a robust conference agenda which will feature breaking advances in Neuro-Oncology research and Neurosurgical techniques. (braintumour.ca)
The advances in clinical medicine derived from these discoveries were among the compelling impetuses for the Human Genome Project, which aimed to identify the complete set of human genes and make them accessible for further biological study. (simonsfoundation.org)
The complete sequencing of the human genome, announced in 2001, marked the culmination of unprecedented advances in the science of genomics, the study of the genome and its functions. (who.int)
The report1 details the latest advances in genome research and explains how this research could result in clinical applications in many diseases, including those that are endemic in poor countries. (who.int)
Advances in genomics for global health care must be assessed for their relative value in the practice and delivery of health care compared with the costs and efficacy of current approaches to public health, disease control and the provision of basic preventive medicine and medical care. (who.int)
The potential medical applications of genomics are considerable and will lead to major advances in clinical practice but the time-scale is difficult to predict. (who.int)

Our research uses an interdisciplinary, integrative approach to investigate the effects of anthropogenic impact, land use change and environmental pollution on wildlife health and zoonotic diseases. (uni-ulm.de)
Kohane has published several hundred papers in the medical literature and authored a widely-used book on microarrays for integrative genomics. (simonsfoundation.org)

JAX has received more than $7.6 million in philanthropic investment to support vision research, which includes a recent challenge grant as well as the Diana Davis Spencer Foundation's 2020 donation of $2 million and their $1.5 million gift in 2018 to establish the Diana Davis Spencer Foundation Chair for Glaucoma Research at JAX. (jax.org)
In 2018, St. Jude launched an online data-sharing and collaboration platform that provides researchers access to the world's largest public repository of pediatric cancer genomics data. (stjude.org)
Dr. Howard Xu was presented the 2018 CSU Biotechnology Faculty Research Award by Dr. Bill Tong of San Diego State University. (calstatela.edu)
Nominated by his peers, Dr. Xu received the 2018 CSU Biotechnology Faculty Research Award in January 2018 by CSUPERB at the 30th annual CSU Biotechnology Symposium at Santa Clara, CA. The award recognizes faculty members who have done significant work and built an outstanding biotechnology-related research program. (calstatela.edu)

The approach and lessons learned may assist others in determining how best to integrate genomics into their healthcare system. (nature.com)
Pharmacogenomics has the potential of transforming clinical research and improving healthcare in sub-Saharan Africa (SSA). (cambridge.org)
Wallen said that the competency training program is the result of collaboration among the departments of informatics and nursing education, as well as with National Cancer Institute senior nursing research specialist Kathleen Calzone and Jean Jenkins, clinical advisor of the genomic healthcare branch of the NHGRI. (genomeweb.com)
A lot of research projects in various fields - especially healthcare and genomics research -are leveraging open source collaborative-development style approaches. (sandhill.com)

August 23, 2019 - Clarifying Competing Application Instructions and Notice of Publication of Frequently Asked Questions (FAQs) Regarding Proposed Human Fetal Tissue Research. (nih.gov)
July 26, 2019 - Changes to NIH Requirements Regarding Proposed Human Fetal Tissue Research. (nih.gov)
July 22, 2019 - Requirement for ORCID iDs for Individuals Supported by Research Training, Fellowship, Research Education, and Career Development Awards Beginning in FY 2020. (nih.gov)

To analyze personal genomics, a technique called DNA sequencing is needed and it is used to determine any disorders or polymorphisms in DNA sequences. (wikipedia.org)
We are now using multiple approaches to analyze cancer genomes even more deeply. (stjude.org)
They plan to analyze clinical, genomic, pathological, and other molecular data collected from the frozen brain tissue of 1,000 volunteers from the Religious Order Study and the Rush Memory and Aging Project. (genomeweb.com)
This open-source software package enables scientists to analyze sequence and microarray profile data in conjunction with emerging biomedical information, such as pathways and genotypic data, as well as more traditional clinical data, whose research potential in a genomic context has so far eluded the research community. (the-scientist.com)
Our project will use the massive amounts of information available from genome research to identify, analyze and develop potential enzymes in fungi that we could use as catalysts to produce biofuels and other plant-based products. (concordia.ca)
The goal of this genomic research is to identify, analyze and develop potential enzymes in fungi that can be used to convert plant material into biofuels, biochemicals and other products for industrial use. (concordia.ca)
NPH will use artificial intelligence (AI)-based approaches to analyze information provided by participants in order to develop algorithms that predict responses to dietary patterns. (cdc.gov)
The NIH National Human Genome Research Institute's Encyclopedia of DNA Elements (ENCODE) was a project created to understand and analyze the human genome. (medlineplus.gov)

The Childhood Solid Tumor Network and PROPEL support preclinical research into pediatric solid tumors and blood cancers such as leukemia. (stjude.org)
The emergence of oncogene mutations associated with anti-EGFR treatment resistance, which include KRAS and EGFR T790M, is the main cause of disease progression after initial positive response to first-line colorectal and lung cancer therapies," said Marek Minarik , Ph.D., lead investigator and the director of the Center for Applied Genomics of Solid Tumors at Genomac. (prnewswire.com)
Headquartered in Prague, Czech Republic , the Center for Applied Genomics of Solid Tumors (CEGES) is a subsidiary of Genomac International, Ltd., a private biotech company founded in 2001. (prnewswire.com)

Brain Tumour Foundation of Canada partners with the Brain Tumor Funders' Collaborative to extend the impact of research dollars. (braintumour.ca)
By working together we can accelerate progress in brain tumor research. (braintumour.ca)
The human tumor samples provide the global research community with a free resource to advance understanding and treatment of pediatric cancer. (stjude.org)
The projects described in this dissertation begin by characterizing the mutational landscape across tumor cohorts, followed by more in depth analyses of their expression landscapes. (wustl.edu)
We used algorithmic approaches to identify mutations that confer immune recognition of tumor cells, as well as deconvolute the infiltrating immune microenvironment in bulk tumor RNA samples. (wustl.edu)
This dissertation describes studies that effectively address challenges in cancer genomics, including tumor sampling, heterogeneity within and across cancer types, and the role of the microenvironment, in order to successfully establish models for studying human cancers as well as identify correlates of therapeutic response. (wustl.edu)
The main focus of CEGES is the development and application of new technologies and approaches for molecular tumor profiling to diagnose and treat solid cancers. (prnewswire.com)
We have developed genetic and genomics approaches to explain the large variance in anti-tumor immunity across people, and to discover how tumors evolve to resist productive immunity. (massgeneral.org)
Dr. Tuhin Guha is a postdoctoral research fellow in the Snyder lab, where he is using highly multiplexed imaging modalities, such as CODEX and Nanostring to understand the precancer/tumor microenvironment from Familial Adenomatous Polyposis (FAP) More patient samples. (stanford.edu)

A primary goal of my research is to understand the genetic bases of reproductive transition of plants (flowering) in response to environmental signals, and to clarify how these mechanisms have evolved. (csun.edu)
Two major research thrusts in the lab are to determine plant mechanisms that (i) dictate the development of symbiotic root nodules and (ii) recruit beneficial microbes. (sdstate.edu)
My scientific research focused on unravelling the mechanisms of plant-microbe interactions with a particular emphasis on the effect of drivers of global change such as land use intensity, climate change, as well as plant species identity and genetic diversity on the plant associated and rhizosphere soil microbiomes. (ufz.de)
John Cryan talks about the research that exploring mechanisms of how gut bacteria could influence our brain and behavior. (bvsalud.org)
The theoretical part covers the molecular principles and mechanisms underlying the experimental approaches. (lu.se)

Our research aims to advance translational, regenerative and personalized medicine. (ucl.ac.uk)
This NIHR Blood Transplant Research Unit project aims to identify and validate donor-specific biomarkers which are predictive of recipient outcome following haematopoietic stem cell transplantation. (ucl.ac.uk)
Using a systems medicine approach, this project aims to develop personalised treatments for multiple sclerosis based on multi-omics biomarkers. (ucl.ac.uk)
Fascinated by the complexity of biological systems, my research aims at bringing understanding on how microbes respond to their environment and at using this knowledge to turn cells in powerful factories. (tudelft.nl)
One of our current research aims is to develop improved association tests for genome-wide association studies (GWAS) that scale to millions of samples while accounting for technical and biological confounding factors. (embl.org)
Our methodological research aims tie in with experimental collaborations. (embl.org)
That's why she has taken a leadership role in the National Institutes of Health All of Us project, which aims to add diversity to available genomic sequences. (ashg.org)
This project aims to employ different cutting-edge bioinformatics techniques to predict deleterious scores of mutations across a comprehensive dataset of avian genomes, representing a broad swath of the avian phylogenetic tree, and compare their accuracy. (lu.se)

Personalized genomics is the human genetics-derived study of analyzing and interpreting individualized genetic information by genome sequencing to identify genetic variations compared to the library of known sequences. (wikipedia.org)
How does your work in the field advance human genetics research? (ashg.org)

Research involving wet and dry lab aspects of multiomics analyses, and two coronavirus research projects including handling of positive SARS-COV-2 samples. (stanford.edu)

In the competency, they train you to do the pedigree, but it's very manual, on paper," noted Michelle Lardner, deputy CIO for clinical research informatics at the center. (genomeweb.com)
The pilot set to start in the next few months will be led by Sharon Flynn - an NIH nurse educator who was a part of the original group that created the competency training course - in conjunction with clinical research nurses in an ambulatory setting, according to Wallen. (genomeweb.com)
The mission of the Data Science Shared Resource (DSSR) is to provide professional expertise in biostatistics, bioinformatics and clinical research informatics for all Vanderbilt-Ingram Cancer Center investigators. (vicc.org)
Less than a century ago, the discovery of new inherited diseases accelerated through clinical research and analysis. (simonsfoundation.org)
AMDeC actively works with its members to foster partnerships for basic-science and clinical research projects, to build genomics and other core facilities, and to expand New York's research infrastructure. (the-scientist.com)
Upon completing postgraduate work at the Medical Research Council's Clinical Research Centre, Harrow, UK he "emigrated" to the USA to take up postdoctoral positions first at New York University School of Medicine and then Yale University. (cam.ac.uk)

The project focused mainly on single nucleotide polymorphisms (SNPs) distributed within and across populations, and designed high density SNP arrays to screen for polymorphisms, allowing researchers to search for genes involved in common human diseases. (wikipedia.org)
These projects have been completed with the aid of DNA sequencing techniques which allow for the identification of genetic variations in each genome, thus personally diagnosing genetic diseases. (wikipedia.org)
OMEGA will overcome this limitation with open access reference genomes from PGP and GIAB that will be customised by machine learning approaches with quantifiable (epi)genetic variants and signatures of clinically relevant phenotypes and diseases for diverse ancestries. (ucl.ac.uk)
JAX researchers discuss how philanthropy is furthering scientific research and training activities in the field of neurodegenerative diseases of the eye. (jax.org)
The gifts fund the Laboratory's scientific research and training activities in the field of neurodegenerative diseases of the eye, including graduate and postdoctoral fellowship training. (jax.org)
Without these amazing donations, we would not have been able to get going so quickly on our research to understand how aging contributes to increased risk for glaucoma and other diseases of the eye," says Howell. (jax.org)
Not every trial at the NIH Clinical Center collects DNA samples, but most trials there focus on rare diseases, which often rely on genomics for diagnosis, NIH spokeswoman Molly Freimuth said. (genomeweb.com)
Dr. Varuna Chander is a postdoctoral fellow in the Snyder lab investigating the genomic basis of human diseases, both rare and common using multi-omics and machine learning approaches. (stanford.edu)
As a NLM fellow of Biomedical Informatics and Data Science, Dr. Chander led projects investigating the molecular causes of rare diseases and also the relationship between somatic mosaicism in blood and cardiovascular disease risk. (stanford.edu)
Alongside, she also led collaborative projects employing the role of structural variation in genetic diseases. (stanford.edu)
This platform will be a key stepping stone for a new translational research component, bringing a tremendous array of genomic tools, both experimental and computational, to bear on the analysis of the genetic basis for common diseases. (the-scientist.com)
Although development costs associated with genomics are likely to be high, some applications (e.g. control of inherited anaemias and diagnosis of infectious diseases) have already been shown to be cost-effective compared to current practices. (who.int)
Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. (cdc.gov)
Ritchlin is co-leading a new research team dedicated to psoriatic spectrum diseases as part of the $64.5 million Autoimmune and Immune-Mediated Diseases Program (AIM) of the Accelerating Medicine Partnership (AMP), a huge public-private partnership involving the National Institutes of Health that is collecting and analyzing troves of biological data in order to better understand the cellular and molecular compositions and interactions that lead to disease. (medscape.com)
Scientists at the International Agency for Research on Cancer (IARC) have formed the Rare Cancers Genomics Team to develop innovative research projects on rare cancers to improve the prognosis of patients diagnosed with these rare diseases. (who.int)
Despite the high collective occurrence of rare cancers, basic science research, clinical trials, and approval of new therapies for these rare diseases are lacking. (who.int)
The goal is to find new in vitro approaches to understand and treat human diseases caused by the environment. (medlineplus.gov)

JAX Professor Gareth Howell , Ph.D., holds the Diana Davis Spencer Foundation Chair for Glaucoma Research. (jax.org)
Located within the Department of Animal- and Aquacultural Sciences, this group includes 2 full-time professors, 1 associate professor, 11 researchers, 8 PhD students and 9 research technicians. (fems-microbiology.org)
Following industry and academic positions in Sweden, Canada, New Zealand and the US, Paul O'Toole is now Professor of Microbial Genomics at University College Cork, Ireland. (cam.ac.uk)
Gail Jarvik, MD, PhD, the Arno G. Motulsky Endowed Chair in Medicine, Joint Professor of Medicine and Genome Sciences, and Head of the Division of Medical Genetics (only the third since the founding of the division in 1957), an Adjunct Professor of Epidemiology at the UW Medical Center (UWMC) and an Affiliate Member of the Fred Hutchinson Cancer Research Center. (ashg.org)
The challenge right now is that we don't understand the discrete and overlapping endotypes that underlie the phenotypes or domains" of PsA, said Christopher Ritchlin, MD, MPH, professor of medicine in the division of allergy/immunology and rheumatology and the Center of Musculoskeletal Research at the University of Rochester (N.Y.), who spoke about PsA at the annual research symposium of the National Psoriasis Foundation. (medscape.com)

For his thesis, Apollo applied genomic approaches to dissect disease-promoting interactions between members of the oral microbiota. (ccf.org)
The aim of his research group is to characterize polymicrobial-host interactions within the oral cavity that regulate susceptibility to disease. (ccf.org)
Genetics, genomics, and diet interactions in obesity in the Latin American environment. (cdc.gov)
Precision Environmental Health is a research area that helps scientists learn how interactions between the environment and genetics can affect a person's health. (medlineplus.gov)

Together we have joined forces to support the Defeating Embryonal Cancer in Young People Together (DECRYPT) Research Grant, which will open in early 2023. (braintumour.ca)

As the chief intramural research agency of USDA, the Agricultural Research Service plays a foundational role in supporting American agriculture. (usda.gov)

Human Genome Project (HGP) is a research project conducted by universities and research centers throughout six countries with the primary goal of determining the complete sequence of bases of the entire human genome and identifying the complete set of human genes. (wikipedia.org)
Building on a strong publication record and a history of successful clinical collaborations, Genomac has earned recognition as one of the leading centers in the field of molecular cancer research in the region. (prnewswire.com)
Kohane's i2b2 project is currently deployed internationally to over 120 major academic health centers to drive discovery research in disease and pharmacovigilance (including providing evidence on drugs that ultimately contributed to "boxed warning" by the FDA). (simonsfoundation.org)
Since its inception in 1997, the AMDeC Foundation, Inc. (AMDeC), a not-for-profit consortium of 35 of New York's preeminent medical schools, academic health centers, and major medical research institutions, has paved the way for its members to participate in large-scale collaborations. (the-scientist.com)
Through these and other initiatives AMDeC continues to build upon New York's unique capabilities as a center of world-class research institutions, academic medical centers, and hospitals. (the-scientist.com)

Large scale sequencing initiatives and discovery-based research projects address gaps in understanding the clinical significance of genetic variation. (nature.com)
In 2013, as deputy chief nurse officer for research and practice development, Wallen was in charge of nursing education and practice and quality initiatives for the research hospital. (genomeweb.com)
The groups have worked together to fund two previous initiatives (details below) and are now exploring a third joint project. (braintumour.ca)
In life sciences research, data is generated from a variety of sources, including biological research, data-intensive technologies such as quantitative imaging, environmental biodiversity studies, large population cohorts, plant and livestock breeding programs, multi-national clinical trials and e-health initiatives. (newswire.ca)
Such initiatives are now heralded as essential for translational and cross-institutional approaches to biomedical research. (the-scientist.com)
Two of its flagship initiatives include the Integrated Genomics Program and the New York Cancer Project. (the-scientist.com)

Our research group combines mathematics and genomics to address clinically important problems in hematology and immunology. (lu.se)
Beneficially, the lab has developed several methods for interpreting complex genomics data and applied these to problems in hematology. (lu.se)

In addition, Dr. Xu provides research training and mentoring to undergraduate and graduate students from Departments of Biological Sciences and Chemistry & Biochemistry. (calstatela.edu)
She earned a Bachelor of Science in medical biochemistry and a Ph.D. in plant biochemistry from the University of London and completed a post-doctoral research fellowship in baculovirus expression at the University of Oxford. (isbr.info)

We have remained at the forefront of medicine by fostering a culture of collaboration, pushing the boundaries of medical research, educating the brightest medical minds and maintaining an unwavering commitment to the diverse communities we serve. (massgeneral.org)
Research article describing soybean nodule and lateral root GRNs work by post-doc Shuchi Smita published in collaboration with Qin Ma lab ( in silico plants ). (sdstate.edu)
Approaches such as collaboration between developed and developing countries, public-private partnerships and establishment of regional and local networks may take the field forward. (who.int)

In 2010, St. Jude Children's Research Hospital and Washington University School of Medicine launched a $65 million, three-year project to sequence the complete normal and cancer genomes of 600 pediatric cancer patients. (stjude.org)
The St. Jude-Washington University Pediatric Cancer Genome Project became the world's most ambitious effort to discover the origins of childhood cancer and seek new cures. (stjude.org)
In 2014, the Pediatric Cancer Genome Project laid the foundation for the creation of the St. Jude Cancer Predisposition Clinic. (stjude.org)
These tools have reduced the data error rate, recognized mutations driving cancer and made it easier for researchers worldwide to interrogate data-either their own or data generated by the Pediatric Cancer Genome Project. (stjude.org)
This research project will accelerate the use of genomics in pediatric medicine by creating and safely testing new methods for using information obtained from genomic sequencing in the care of newborns. (genome.gov)

The Vanderbilt Chemical Synthesis and High-throughput Analytics Shared Resource (CSHTASR) provides state-of-the-art capabilities for the Vanderbilt-Ingram Cancer Center researchers, and works to harness the power of chemistry and assay technologies to support research requiring the application or discovery of chemical tools to answer biological questions. (vicc.org)
This will help achieve the Integrated Genomics Program's overarching goal: to create the first large-scale biomedical research platform for collaborative science in pursuit of new biological knowledge, personalized diagnostics, and therapeutic tools. (the-scientist.com)
Prof Jeantine Lunshof's research interests are concerned with philosophical research ethics in the field of genomic sciences and biological engineering where disruptive technological innovations call for epistemological and normative exploration. (isbr.info)
In the past, transla- progesterone receptor (PgR) expression, and all of the tional research focused on single biological markers following features: pT 6 2 cm, grade I, age P 35 years which could putatively discriminate patients' prognosis should be considered in this low-risk category, whereas or treatment response. (lu.se)
Perhaps the weak link in the approach of the tient outcome is also highly variable and depends on Lund group is their faith in the reproducibility of biological differences among the tumours. (lu.se)

Organisations and governments seeking to implement genomics into clinical practice face numerous challenges across multiple, diverse aspects of the health care system. (nature.com)
However, numerous barriers to the implementation of genomics into clinical practice exist. (nature.com)
Conventional, tried and effective approaches to medical research and medical practice must not be neglected while the medical potential of genomics is being explored. (who.int)
Our research has contributed to the understanding of inherited susceptibility to multiple myeloma, the identification of the gene behind the Vel-blood group and a diagnostic tool for the blood group used in clinical practice. (lu.se)

GEP studies also assess non-genetic throughput genomic techniques and the exposures, partly in recognition of the related bioinformatics to support GEN's importance of non-genetic factors in large-scale molecular epidemiology driving cancer incidence, and also to projects and other IARC genomics facilitate accurate assessment of gene- projects. (who.int)

Previous postdoctoral training involved modified CRISPR-Cas system for increasing the efficiency of gene editing in mammalian cells/ Xenopus embryos and alternative gene therapy approach to treat various muscle disorders using the diseased mouse models. (stanford.edu)

Particularly for pa- an increasing gap between the resources employed for tients at a low-risk of recurrence, a balance must be basic and translational research and actual patient struck between the under-treatment of the few patients benefits and overall social gain. (lu.se)

Accordingly, a wide-ranging consultative process was undertaken, engaging scientists, clinicians, ethicists, public and private funders of genomics research, health policy-makers, nongovernmental organizations and civil society groups concerned with the ethical, legal and social implications of genomics. (who.int)

However, these approaches were more specifically designed to relate the mutational and gene expression landscapes to clinical and pathologic responses to treatment. (wustl.edu)

International HapMap Project is an international research project facilitating identification of genotype-phenotype correlation by genome-wide association study (GWAS). (wikipedia.org)

Brain Tumour Foundation of Canada is happy to announce our partnership with Kindred Foundation, Cancer Research Society, Phoebe Rose Rocks Foundation, Miracle Marnie, Childhood Cancer Canada and Tali's Fund. (braintumour.ca)
Current clinical trials designed to improve treatment and outcomes for children with cancer reflect the findings and insights gained from the project. (stjude.org)
We are also developing a state-of-the-art clinical genomics program to better diagnose and treat children with cancer. (stjude.org)
Next generation sequencing, especially of DNA and RNA, has been rapidly integrated into preclinical and clinical cancer research. (wustl.edu)
The Cell Imaging Shared Resource (CISR) provides access to cutting-edge technology and expert technical support for microscopic observation and analysis of tissue and cellular anatomy and physiology essential to modern cancer research. (vicc.org)
The CISR maintains the full range of advanced light and electron microscopy and digital imaging capabilities fundamental to current cancer research methodology. (vicc.org)
Through this Shared Resource, Vanderbilt-Ingram Cancer Center investigators obtain both significant cost advantages and vital access to a large array of valuable, advanced instrumentation and dedicated expertise, thus enabling and accelerating cancer research that would otherwise be reduced in quantity and quality. (vicc.org)
The AMDeC New York Cancer Project, a pioneering undertaking to determine the environmental and genetic factors that cause cancer, demonstrated the feasibility of large prospective population research studies in New York. (the-scientist.com)
The project, which set out to improve both cancer prevention and treatment, used an extensive network of hospital members to set up sites throughout the city for the recruitment of a very diverse cohort. (the-scientist.com)
Sources of funding include e.g. the Swedish foundation for Strategic Research, the Knut and Alice Wallenberg Foundation, The Swedish Childhood Cancer Foundation and Swedish Research Council. (lu.se)
A review of the Mediterranean diet and nutritional genomics in relation to cancer in women. (cdc.gov)
E. Biganzoli, P. Boracchi / European Journal of Cancer 40 (2004) 1803-1806 re-analysis of Eden and colleagues are suitable for Some of the claims for the medical benefits of genomics have developing new prognostic classifications and/or com- undoubtedly been exaggerated, particularly with respect to the time-scale required for them to come to fruition. (lu.se)
The toxicogenomic signatures from analysed samples are subsequently linked to -omics patterns found in the human cancer genomics databases. (who.int)

Dr. Xu's research and student training projects are funded by grants from National Institutes of Health ( NIH ), U.S. Department of Homeland Security ( DHS ), U.S. Department of Defense ( DoD ), U.S. Department of Education ( DoEDU ), California State University Program for Education and Research in Biotechnology ( CSUPERB ) and California State University, Los Angeles ( CSULA ). (calstatela.edu)
Dr. Xu's biotechnology research focuses on fighting bacterial infections and the rise of antibiotic-resistant strains with anti-virulence factors in combination with antibiotics. (calstatela.edu)
Some projects focus on developing and evaluating non-traditional approaches that include biotechnology techniques, genomics, genetics, and other cutting-edge approaches needed to respond and adapt quickly and efficiently to unique, new and emerging problems that face our food production system. (usda.gov)

We use computational and data science approaches to study genetic and epigenetic variations and how they modulate genome function. (ucl.ac.uk)
Even when genomics is not part of a particular study, the NIH Clinical Center often asks trial participants to consent to providing samples for potential later use. (genomeweb.com)
My research is articulated around two major themes, the study of central carbon metabolism and its regulation, and uncoupling growth from product formation. (tudelft.nl)
This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial. (nih.gov)
This approach has been to use genomic and typical y occurs within GEP, which bioinformatic techniques to complement has a primary interest in the analysis more traditional approaches for the study and identification of common genetic of rare genetic variants. (who.int)
Therefore, providing new approaches to study rare cancers that help to overcome the intrinsic limitation of low numbers is key to improve the clinical management of patients. (who.int)
In vitro refers to cell-based research, and genomics is the study of the complete set of an individual's DNA. (medlineplus.gov)

In particular, our ERC Synergy project DECODE will pioneer the systematic perturbation of hundreds of key regulators in vivo , combined with single-cell profiling to comprehensively phenotype such mutants. (embl.org)
The congruence of key paradigms in the nutrition and microbiome disciplines validates current recommendations in dietary guidelines, and the systematic incorporation of microbiome science into nutrition research has the potential to further improve and innovate healthy eating. (cdc.gov)

9 Increasingly, there is recognition of the importance of implementation research to identify strategies which assist the adoption of genomics by clinicians. (nature.com)

Here, we present the Melbourne Genomics Health Alliance demonstration project as an exemplar of a collaborative, holistic approach to phased implementation of genomics across multiple autonomous institutions. (nature.com)

The AMDeC Integrated Genomics Program, an alliance of the AMDeC Microarray Resource Center and Bioinformatics Core, seeks to bring together many of these different kinds of data and analysis tools. (the-scientist.com)
These programmes for conventional factors rather than for expectations have been increased following the intro- c-DNA microarray research. (lu.se)

Ms Nicole Suty (until June 2015) standard approaches, and in all cases multi-omics analysis (Assi et al. (who.int)

Whole exome sequencing is the method to sequence all exons in genomics. (wikipedia.org)
The past decade has been characterized by unprecedented progress in the field of descriptive genomics, increasing the capacity to finely map regulatory regions and DNA sequence variants, which are responsible for the phenotypic differences between individuals as well as disease susceptibility. (tigem.it)
A complete and accurate set of human protein-coding gene annotations is perhaps the single most important resource for genomic research after the human-genome sequence itself, yet the major gene catalogs remain incomplete and imperfect. (nih.gov)

Lucas focusses mainly on designing mathematical models, algorithms and data structures to analyse bacterial genomic data, to support our projects like understanding Enterococcus antibiotic resistance. (broadinstitute.org)

It motivated scientists all over to carry out several projects together to understand the human genome. (wikipedia.org)
Their generosity is advancing breakthrough research into glaucoma, age-related macular degeneration, ocular signs of Alzheimer's disease and so much more, and their support of our scientists and our work means the world to us. (jax.org)
These curated, high-level scientific talks feature leading scientists and mathematicians and are intended to foster discourse and drive discovery among the broader NYC-area research community. (simonsfoundation.org)

International genetics communities have spared no effort from the past and have gradually cooperated to prosecute research projects to determine DNA sequences of the human genome using DNA sequencing techniques. (wikipedia.org)
At the time, large-scale sequencing projects focused primarily on adult cancers. (stjude.org)
The project included whole exome and whole transcriptome sequencing of an additional 1,200 patients, which included 23 different cancers. (stjude.org)
In recent years, the increase of data production has been particularly dramatic in genomics and related research fields, specifically in the area of genome sequencing. (newswire.ca)
In Chapter 2, comprehensive sequencing approaches were used to discover the somatic alterations and signaling events leading to spontaneous tumorigenesis in a genetically engineered mouse model (NRL-PRL) for estrogen receptor positive breast cancers, driven by overexpressed prolactin ligand (PRL) in the mammary glands of female mice. (wustl.edu)
Awards of $5 million to four grantees have been made in fiscal year 2013 under the Genomic Sequencing and Newborn Screening Disorders research program. (genome.gov)
Participation is voluntary for those research studies that involve returning results of DNA sequencing to families and physicians, and requires that families provide informed consent. (genome.gov)
The MUTSPEC 2.0 project was developed to accommodate a highly integrated design to identify mutational (and other toxicogenomic) signatures of carcinogens derived by genome-scale sequencing analysis of mutually complementary and cross-validating systems. (who.int)
Thus, the research programme gene or genome-wide genotyping of GCS complements that of GEP, studies, as well as sequencing work. (who.int)

This project also stored the genetic information in public databases and had a role in the improvement of tools for data analysis. (wikipedia.org)
Using Open Consent , PGP-UK provides genomic, epigenomic, transcriptomic and trait data under Open Access to advance personal and medical genomics and to promote Citizen Science. (ucl.ac.uk)
The European Standards for Precision Medicine (EU-STANDS4PM) Consortium will initiate an EU-wide mapping process to assess and evaluate strategies for data-driven in silico modelling approaches. (ucl.ac.uk)
GCGR is generating a comprehensive collection of research tools, materials and associated data to lay the foundations for future basic and translational studies into glioma. (ucl.ac.uk)
CIGENE has a strong aqua- and agri- research profile, with key strengths in the application of 'omics' data to understand the genetic architecture of complex traits. (fems-microbiology.org)
These projects will strengthen the development of new tools to help provide maximum value from research investments in genomics and related fields - areas that produce a massive and ongoing influx of data. (newswire.ca)
A second aim is developing approaches for dimensionality reduction that allow the integration of data across omics modalities, profiled across space and time (see figure). (embl.org)
June 5, 2020 - Notice of Special Interest (NOSI) of NIDCR in Supporting Dental, Oral, and Craniofacial Research Using Bioinformatic, Computational, and Data Science Approaches. (nih.gov)
Other research focuses on the analysis of de-identified data, which may be useful in developing and improving screening tests. (genome.gov)
It will test a new approach to newborn screening, in which genomic data are available as a resource for parents and doctors throughout infancy and childhood to inform health care. (genome.gov)
GEN's projects usual y involve extensive may have a larger effect than common fieldwork in col aboration with external single-nucleotide polymorphisms but investigators in order to develop large- that are not sufficiently frequent to scale epidemiological studies with be captured by current genome-wide appropriate clinical and exposure data, association genotyping arrays. (who.int)
With a view to addressing these challenges, increasing the pool of data, and facilitating access to it, the Rare Cancers Genomics Team is strongly committed to open science. (who.int)
We used two approaches: an online survey using a specially designed data collection tool and a review of publicly available literature using PubMed, IMEMR, Google Scholar, Google, and INSERM search engines. (who.int)

In this thesis, the prob- lem of discrete multistage optimization processes and possible distributed solution approaches will be discussed. (grin.com)

Anatomy1

Organisms1

Diseases2

Chemicals and Drugs3

Analytical, Diagnostic and Therapeutic Techniques and Equipment49

Psychiatry and Psychology18

Phenomena and Processes31

Disciplines and Occupations42

Anthropology, Education, Sociology and Social Phenomena36

Technology, Industry, Agriculture3

Humanities8

Information Science45

Named Groups10

Health Care90

Geographicals8

Genetics and genomics12

Epigenomics3

Biology35

Comparative11

Proteomics3

Functional5

Conservation Genomics1

Population genetics1

20222

Evolutionary2

Laboratory3

Advances6

Integrative2

20184

Healthcare4

20193

Analyze8

Solid tumors3

Tumor9

Mechanisms5

Aims8

Human Genetics2

Analyses1

Clinical research6

Diseases17

Professor5

Interactions4

20231

Agricultural Researc1

Centers5

Initiatives6

Problems in hematology2

Biochemistry2

Collaboration3

Pediatric5

Biological5

Practice4

Epidemiology1

Postdoctoral1

Translational research1

Funders1

Gene expression1

Genome-wide1

Cancer13

Biotechnology3

Study7

Systematic2

Clinicians1

Collaborative1

Microarray2

Multi-omics1

Sequence3

Bacterial1

Scientists3

Sequencing9

Data13

Thesis1