Renal cardiovascular. Medical search. Frequent questions

Knowledge to be gained from this proposal can influence strategies to minimize the risk of chronic kidney and cardiovascular disease among first responders. (cdc.gov)
Cardiovascular mortality is extremely high in end-stage renal disease. (nih.gov)
In patients who had preexisting vascular disease or diabetes combined with an additional cardiovascular risk factor, mild renal insufficiency significantly increased the risk for subsequent cardiovascular events. (nih.gov)
A kidney transplantation improves both quality of life and life expectancy of patients with chronic renal disease. (rug.nl)
Despite this, their risk of developing cardiovascular disease is five times higher as compared to the general population. (rug.nl)
Therefore, it is of vital importance to prevent the occurrence of cardiovascular disease after kidney transplantation. (rug.nl)
Since baseline serum creatinine level and GFRs may not be readily available, the consensus committee recommended the use of the Modification of Diet in Renal Disease (MDRD) equation to estimate the patient's GFR/1.73 mm based on serum creatinine level, age, gender, and race. (medscape.com)
We also lack hard endpoints for tirzepatide in obesity, but several ongoing studies may provide data on the impact of tirzepatide on cardiovascular outcomes (SURMOUNT-MMO), nonalcoholic steatohepatitis (SYNERGY-NASH), heart failure with preserved ejection fraction (SUMMIT), chronic kidney disease (TREASURE-CKD), and obstructive sleep apnea (SURMOUNT-OSA). (medscape.com)
Interface between renal disease and cardiovascular illness. (medlineplus.gov)
Use of NSAIDs, dehydration, and preexisting renal disease are all predisposing factors. (mhmedical.com)
Results: During a median of 3.8 years (17,451 person-years in total), there were 2,163 deaths, of which 826 were related to cardiovascular disease. (lu.se)
The Feinberg Cardiovascular and Renal Research Institute is seeking an enthusiastic and highly motivated scientist for expansion of basic and translational studies related to molecular mechanisms of kidney disease. (northwestern.edu)
The primary safety end point was a composite of death, end-stage renal disease, embolic events resulting in end-organ damage, renovascular complications, or hypertensive crisis at 1 month or new renal-artery stenosis of more than 70% at 6 months. (amegroups.org)
Severe renal arteriosclerosis (r‐ASCL) can predict atherosclerosis cardiovascular disease (ASCVD) in LN, according to a study. (medjournal360.com)
Renal arteriosclerosis strongly associated atherosclerotic cardiovascular disease risk in lupus nephritis. (medjournal360.com)
Possible complications of renal artery stenosis are chronic kidney disease and coronary artery disease. (wikipedia.org)
At the present time, there is a paucity of data about the role of L- arginine in chronic cardiovascular and kidney disease in dogs. (unicam.it)
We sought to compare the risk of end-stage renal disease (ESRD), ischemic heart event (IHE), congestive heart failure (CHF), cerebrovascular accident (CVA), and all-cause mortality among 470,386 individuals with resistant and nonresistant hypertension (non-RH). (hypertension.qc.ca)
Over the course of NIOSH's 50-year history, occupational chronic diseases, including cancer, cardiovascular disease, and adverse reproductive outcomes have always been a significant public health burden and source of economic costs. (cdc.gov)
Since its inception in 2004, the Cancer, Reproductive, Cardiovascular, and Other Chronic Disease Prevention Program (CRC), within the NIOSH Program Portfolio , has provided leadership in the prevention of work-related chronic diseases and conditions. (cdc.gov)
and (4) other chronic diseases such as occupational neurologic and renal disease. (cdc.gov)
One example of the important CRC etiologic research in cardiovascular disease research is the Buffalo Cardio-Metabolic Occupational Police Stress Study. (cdc.gov)
The Renal and Cardiovascular Disease Research Laboratory examines the efficacy of non-pharmacological interventions on the health and quality of life of people with chronic kidney disease (CKD). (illinois.edu)
CKD patients often suffer from poor health and quality of life due to a high prevalence of co-morbid conditions, including cardiovascular disease, muscle wasting, bone disorders, and cognitive dysfunction. (illinois.edu)
Objective: To quantify direct medical costs of fractures and cardiovascular diseases among endstage renal disease (ESRD) patients. (johnshopkins.edu)
Methods: Medicare claims data from year 2001 of the United States Renal Data System were used to quantify direct medical costs of acute episodic events (acute myocardial infarction (MI), stroke, heart valve repair, heart valve replacement, fractures) and chronic conditions (arrhythmia, peripheral vascular disease (PVD), heart valve disease (HVD), congestive heart failure (CHF), coronary heart disease, and non-acute stroke). (johnshopkins.edu)
Dr. Longenecker's research interests have focused on non-communicable diseases, particularly cardiovascular and renal disease, hypertension, and diabetes. (drexel.edu)
He also has experience in national health surveys in Kuwait such as the World Health Organization STEPS Study and the Kuwait Salt Intake and Renal Disease Study, which have been used to inform public health practice in that country. (drexel.edu)
In this review, current and potential future applications for the RF coil technology in cardiovascular, neurovascular, and renal disease will be discussed. (mdc-berlin.de)
1. The burden of cardiovascular disease is increasing rapidly in Africa, and it is now a public health problem throughout the African Region. (who.int)
Cardiovascular disease has a major socioeconomic impact on individuals, families and societies in terms of health-care costs, absenteeism and national productivity. (who.int)
The most important cardiovascular diseases (CVDs) in the African Region are those related to atherosclerosis, cardiomyopathies and rheumatic heart disease. (who.int)
5. The WHO STEPwise approach to surveillance of noncommunicable diseases in general and cardiovascular disease in particular (otherwise known as STEPS) is based on community evaluation of eight risk factors (see Figure 1). (who.int)
The Faculty of Medicine offers the degree of Doctor of Philosophy in seven program areas: Bioscience of Health and Disease, Cardiovascular and Renal Sciences, Clinical Epidemiology, Community Health, Human Genetics, Immunology and Infectious Diseases and Neurosciences. (mun.ca)
Adjusted Cox regression assessed the separate relevance of the baseline UACR and the UACR change to the risk of developing stages 4 to 5 CKD and end-stage renal disease (ESRD). (ox.ac.uk)
Associations were weaker for shorter exposure windows (and for cardiovascular disease or death), but strengthened after allowing for regression to the mean. (ox.ac.uk)

Cardiovascular mortality risk also is increased in selected (high-risk) individuals with mild to moderate impairment of renal function. (nih.gov)
We investigated the association of renal function with all-cause and cardiovascular mortality in a population-based cohort and explored potential mechanisms underlying any such relationship. (nih.gov)
Renal function was inversely associated with all-cause and with cardiovascular mortality. (nih.gov)
Mild to moderate loss of renal function is strongly associated with an increased risk of cardiovascular mortality. (nih.gov)
Cardiovascular diseases not only result in increased mortality, they also lead to damage of the renal graft, even when protective drugs are being used. (rug.nl)
In patients with kidney injury, measuring changes in the SOFA score in the first 24 hours of renal replacement therapy (RRT) can identify patients at high risk for mortality. (medscape.com)
The secondary end points evaluate the effectiveness of revascularization in important subgroups of patients and with respect to all-cause mortality, kidney function, renal artery patency, microvascular renal function, and blood pressure control. (umn.edu)
Tsioufis similarly describes hypertension as the "most important contributor to cardiovascular mortality and morbidity" and highlights that there are a significant proportion of hypertensive adults whose blood pressure remains uncontrolled. (cardiovascularnews.com)
Rationale & Objective: A healthy lifestyle promotes cardiovascular health and reduces cardiac-related mortality in the general population, but its benefits for people receiving maintenance hemodialysis are uncertain. (lu.se)
Outcome: Cardiovascular and all-cause mortality. (lu.se)
Compared with patients who had a low lifestyle score, the AHRs for cardiovascular mortality among those with medium and high lifestyle scores were 0.73 (95% CI, 0.59-0.91) and 0.65 (95% CI, 0.49-0.85), respectively. (lu.se)
Conclusions: A healthier lifestyle is associated with lower all-cause and cardiovascular mortality among patients receiving maintenance hemodialysis. (lu.se)
Background:Precise effects of albuminuria and low estimated glomerular filtration rate (eGFR) on cardiovascular mortality, all-cause mortality, and renal events in diabetic patients are uncertain.Materials and Methods:A systematic review was conducted of the literature through MEDLINE, EMBASE, and CINHAL from 1950 to December 2010. (elsevierpure.com)
Cohort studies of diabetic patients providing adjusted relative risk (RR) of albuminuria and eGFR for risks of cardiovascular mortality, all-cause mortality, and renal events were selected. (elsevierpure.com)
With regard to the risk of cardiovascular mortality, microalbuminuria (RR 1.76, 95%CI 1.38-2.25) and macroalbuminuria (RR 2.96 95%CI 2.44-3.60) were significant risk factors compared to normoalbuminuria. (elsevierpure.com)
The same trends were seen in microalbuminuria (RR 1.60, 95%CI 1.42-1.81), and macroalbuminuria (RR 2.64, 95%CI 2.13-3.27) for the risk of all-cause mortality, and also in microalbuminuria (RR 3.21, 95%CI 2.05-5.02) and macroalbuminuria (RR 11.63, 95%CI 5.68-23.83) for the risk of renal events. (elsevierpure.com)

The cardiovascular risk associated with early renal insufficiency is unknown. (nih.gov)
Clinicians are often reluctant to use angiotensin-converting enzyme inhibitors in patients with renal insufficiency. (nih.gov)
To determine whether mild renal insufficiency increases cardiovascular risk and whether ramipril decreases that risk. (nih.gov)
The effect of renal insufficiency on the primary outcome (adjusted hazard ratio, 1.40 [95% CI, 1.16 to 1.69]) was independent of known cardiovascular risks and treatment. (nih.gov)
Adherence of chronic renal insufficiency patients to hemodialysis. (pucrs.br)
The consequences of renal ischemia are neuroendocrine activation, hypertension, and renal insufficiency that can potentially result in acceleration of atherosclerosis, further renal dysfunction, myocardial infarction, heart failure, stroke, and death. (umn.edu)
The primary end point is event-free survival from CV and renal adverse events, defined as a composite of CV or renal death, stroke, MI, hospitalization for CHF, progressive renal insufficiency, or need for permanent renal replacement therapy. (umn.edu)
Studies examining the pharmacokinetics of caffeine in neonates with hepatic or renal insufficiency have not been conducted. (drugs.com)

A prospective, single-blind, randomized, sham-controlled trial published in the NEJM examined the impact of catheter-based renal-artery denervation on blood pressure in patients with resistant hypertension. (amegroups.org)
Time in therapeutic range (TTR) of BP is associated with cardiovascular events.OBJECTIVES This study sought to assess the impact of catheter-based RDN on TTR and its association with cardiovascular outcomes in the GSR (Global SYMPLICITY Registry).METHODS Patients with uncontrolled hypertension were enrolled and treated with radiofrequency RDN. (univr.it)
Renal denervation is a catheter-based procedure designed to treat resistant hypertension (high blood pressure that remains uncontrolled even with medication) by using radiofrequency or ultrasound ablation on nerves in the wall of the renal artery. (mddionline.com)
Efficacy of catheter-based renal denervation in the absence of antihypertensive medications (SPYRAL HTN-OFF MED Pivotal): a multicentre, randomised, sham-controlled trial. (medtronic.com)

Urinary albumin-to-creatinine ratio values are often used to guide treatment decisions as albuminuria is known to be a strong predictor of cardiovascular and renal events. (endocrinologyadvisor.com)

Background: Atherosclerotic renal artery stenosis is a problem with no consensus on diagnosis or therapy. (umn.edu)
Conclusions: CORAL represents a unique opportunity to determine the incremental value of stent revascularization, in addition to optimal medical therapy, for the treatment of atherosclerotic renal artery stenosis. (umn.edu)
Renal artery stenosis (RAS) is the narrowing of one or both of the renal arteries, most often caused by atherosclerosis or fibromuscular dysplasia. (wikipedia.org)
Most cases of renal artery stenosis are asymptomatic, and the main problem is high blood pressure that cannot be controlled with medication. (wikipedia.org)
Decreased kidney function may develop if both kidneys do not receive adequate blood flow, furthermore some people with renal artery stenosis present with episodes of flash pulmonary edema. (wikipedia.org)
Renal artery stenosis is most often caused by atherosclerosis which causes the renal arteries to harden and narrow due to the build-up of plaque. (wikipedia.org)
The pathophysiology of renal artery stenosis leads to changes in the structure of the kidney that are most noticeable in the tubular tissue. (wikipedia.org)
medical citation needed] Changes include: Fibrosis Tubular cell size (decrease) Thickening of Bowman capsule Tubulosclerosis Glomerular capillary tuft (atrophy) The diagnosis of renal artery stenosis can use many techniques to determine if the condition is present, a clinical prediction rule is available to guide diagnosis. (wikipedia.org)
The specific criteria for renal artery stenosis on Doppler are an acceleration time of greater than 70 milliseconds, an acceleration index of less than 300 cm/sec² and a velocity ratio of the renal artery to aorta of greater than 3.5. (wikipedia.org)
When high-grade renal artery stenosis is documented and blood pressure cannot be controlled with medication, or if renal function deteriorates, surgery may be resorted to. (wikipedia.org)

Studies among the general population indicate the importance of healthy food to prevent cardiovascular diseases. (rug.nl)
Noncommunicable diseases, in particular cardiovascular diseases, and perinatal conditions together constitute the main causes of death. (who.int)
We know that the sympathetic nervous system is involved in the development, progression and maintenance of hypertension and various other cardiovascular diseases," explains Mahfoud as to why this area is the target of the treatment. (cardiovascularnews.com)
2. One of the reasons for increased cardiovascular diseases (CVDs) worldwide is the increase in aged populations. (who.int)

The primary entry criteria are (1) an atherosclerotic renal stenosis of ≥60% with a 20 mm Hg systolic pressure gradient or ≥80% with no gradient necessary and (2) systolic hypertension of ≥155 mm Hg on ≥2 antihypertensive medications. (umn.edu)
Notably, the new and updated 2023 European Society of Hypertension (ESH) guidelines recommend the use of renal denervation among patients with apparent resistant hypertension as "additive or alternative to increasing medication", as well as in patients with uncontrolled hypertension who are non-adherent or intolerant to antihypertensive drugs. (cardiovascularnews.com)
For Konstantinos Tsioufis (University of Athens, Athens, Greece), a past president of ESH, this upgrade to the guidelines cements renal denervation as the "third pillar" for the treatment of hypertension. (cardiovascularnews.com)
1) Patients with severe resistant hypertension were randomly assigned in a 2:1 ratio to undergo renal denervation or a sham procedure. (amegroups.org)
The authors summarize that this blinded trial did not show a significant reduction of systolic blood pressure in patients with resistant hypertension 6 months after renal-artery denervation as compared with a sham control. (amegroups.org)
This narrowing of the renal artery can impede blood flow to the target kidney, resulting in renovascular hypertension - a secondary type of high blood pressure. (wikipedia.org)
Among the diagnostic techniques are: Doppler ultrasound study of the kidneys Refractory hypertension Auscultation (with stethoscope) - bruit ("rushing" sound) Captopril challenge test Captopril test dose effect on the differential renal function as measured by MAG3 scan. (wikipedia.org)
Seen how the Symplicity Spyral renal denervation procedure works to help treat hypertension. (medtronic.com)
The graduate program in Cardiovascular and Renal Sciences enables students to pursue research and academic studies in selected topics including hypertension and stroke, neural and endothelial control of vasculature and blood pressure as well as physiological mechanisms promoting heart failure. (mun.ca)

We will also correlate stenosis severity with longitudinal renal function and determine the value of stenting from the perspectives of quality of life and cost-effectiveness. (umn.edu)

Only AKI 2 (50% decrease in eGFR) and AKI 3 (75% decrease in eGFR) were considered significant for renal impairment after the procedure. (minervamedica.it)

However, the relationship between β-cells and albuminuria or renal functions in T2DM patients remains unclear. (biomedcentral.com)
Change in Albuminuria and Risk of Renal and Cardiovascular Outcomes: Natural Variation Should Be Taken into Account. (ox.ac.uk)

The primary outcome measure was incidence of cardiovascular death, myocardial infarction, or stroke. (nih.gov)
Methods: CORAL is a randomized clinical trial contrasting optimum medical therapy alone to stenting with optimum medical therapy on a composite cardiovascular and renal end point: cardiovascular or renal death, myocardial infarction, hospitalization for congestive heart failure, stroke, doubling of serum creatinine, and need for renal replacement therapy. (umn.edu)

ST preserved the renal function and attenuated the glomerular shrinkage elicited by HS. (bvsalud.org)
The failure of β-cells compensates for ambient insulin resistance that leads to uncontrolled hyperglycemia resulted in renal glomerular hyperfiltration with microalbuminuria [ 6 ]. (biomedcentral.com)

This narrowing of renal arteries due to plaque build-up leads to higher blood pressure within the artery and decreased blood flow to the kidney. (wikipedia.org)
The vessels of the cardiovascular system are the heart , arteries , capillaries , and veins . (physio-pedia.com)

These have yielded important insights, with SPYRAL HTN-ON MED demonstrating durable reductions in ambulatory systolic blood pressure of -18.7mmHg at three years in patients receiving the renal denervation procedure. (cardiovascularnews.com)

This grant proposal will provide new and important information regarding opioids and the central neurohumoral regulation of renal function and will ultimately provide a new strategy for therapeutic modalities for different cardiovascular and renal pathologies. (grantome.com)

O acometimento renal na hipertensão arterial e diabetes mellitus tipo 2: como identificar e prevenir? (pucrs.br)
Although dysregulated lipid metabolism results in diabetic nephropathy (DN) development in patients with type 2 diabetes mellitus (T2DM), it is not understood whether betatrophin is associated with urinary albumin excretion and renal function. (biomedcentral.com)
A reduction in urinary albumin-to-creatinine ratio (UACR) over a 1-year period is associated with a decreased risk for cardiovascular and renal events, according to the results of a study published in Diabetes Care . (endocrinologyadvisor.com)
Studies have shown that glucagon-like peptide 1 receptor agonists (GLP-1 RAs) have both cardiovascular and renal benefits in patients with type 2 diabetes (T2D) and elevated cardiovascular risk. (endocrinologyadvisor.com)

At baseline, renal function was estimated by the serum creatinine level, the Cockcroft-Gault formula and Levey's equation. (nih.gov)
Acute kidney injury (AKI), formerly called acute renal failure (ARF), is commonly defined as an abrupt decline in renal function, clinically manifesting as a reversible acute increase in nitrogen waste products (measured by blood urea nitrogen [BUN] and serum creatinine levels) over the course of hours to weeks. (medscape.com)

Renal complications following thoracic procedures are uncommon and usually occur in the setting of sepsis. (mhmedical.com)

In a study to assess the definition of renal dysfunction in multicenter, randomized, controlled trials involving critically ill patients, the renal SOFA score is the most commonly used system to quantify renal function at baseline or as a secondary outcome. (medscape.com)

Given the magnitude of weight loss with tirzepatide, I expect many of these trials to provide positive results like the recently announced positive topline results for semaglutide in the SELECT trial, which explored its impact on cardiovascular outcomes in patients with obesity. (medscape.com)

This excess fluid causes a myriad of problems including elevated blood pressure, which leads to an enlarged, dysfunctional heart, and eventually congestive heart failure or related cardiovascular problems. (illinois.edu)

In young infants, the elimination of caffeine is much slower than that in adults due to immature hepatic and/or renal function. (drugs.com)
Caffeine citrate should be administered with caution in preterm neonates with impaired renal or hepatic function. (drugs.com)

Furthermore, an association was observed between the diet and the acidity of the blood and also between dietary patterns, such as low vegetable intake, and high cardiovascular risk. (rug.nl)
To evaluate this association, data from 8,270 participants (35.5% women) with T2D and high cardiovascular risk were analyzed. (endocrinologyadvisor.com)
Additionally, the inclusion of individuals with T2D and high cardiovascular risk may preclude the results of this study from being generalizable to the population at large. (endocrinologyadvisor.com)

Ramipril reduced cardiovascular risk without increasing adverse effects. (nih.gov)

Estimation of renal function by relatively simple methods therefore may be a valuable tool for cardiovascular risk assessment over and above that provided by conventional risk factors. (nih.gov)
BACKGROUND: To report the postoperative renal function stratified according to the visceral vessels (VV) revascularization technique used during proximal abdominal aortic aneurisms (p-AAA) open surgical repair (OR). (minervamedica.it)
The follow-up data of 63.6±21 months shows no significant difference in renal function according to the revascularization technique used compared to the perioperative period. (minervamedica.it)
in critically ill patients, renal dysfunction severity can also be evaluated by combining renal function with functional parameters of other organs (eg, the Sequential Organ Failure Assessment [SOFA] score). (medscape.com)
How does swimming exercise training impact hydro-electrolytic balance, renal function, sympathetic contribution to resting blood pressure and cerebrospinal fluid (CSF) [Na+ ] in rats fed a high- sodium diet from weaning ? (bvsalud.org)
In this study, we sought to investigate the effects of swimming training (ST) on cerebrospinal fluid (CSF) Na+ concentration, sympathetic drive , blood pressure (BP) and renal function of rats fed a 0.9% Na+ (equivalent to 2% NaCl) diet with free access to water for 22 weeks after weaning . (bvsalud.org)
Thus, in this hazard identification study we investigated the effects of inhalation of crude oil vapor (COV) on cardiovascular function. (cdc.gov)
Purpose: The goal of these studies is to identify the CNS sites and neuropathways by which central kappa opioid systems modulate renal function in normal and cirrhotic rats. (grantome.com)
Retrograde tract tracing will be used to identify regions that may influence the activity of parvocellular PVN and also express cFos and/or ICER 2) establish the role of the PVN parvocellular neurons and relevant CNS sites on cardiovascular and renal function produced by central activation of kappa opioids. (grantome.com)

4 While renal cell carcinoma only represents 2% of adult cancers, it is among the most lethal, with approximately 35% of patients dying within 5 years of diagnosis. (ahrq.gov)

We hypothesize that exposure to inhaled particulate matter causes systemic inflammation and endothelial dysfunction that result in chronic kidney and cardiovascular damage. (cdc.gov)

In certain pathophysiological states (e.g., cirrhoses with ascites), changes in the integrity of arterial circulation can lead to profound changes in renal excretion of fluid and electrolytes via the activation of neuronal and humoral mechanisms in the CNS and periphery. (grantome.com)
The activation of central kappa opioids produce a marked water diuresis (an increase in urine flow without a concurrent increase in renal sodium excretion), which is different than traditional diuretics clinically used to date (which, enhance water and sodium excretion). (grantome.com)
Methods: Excitotoxin lesions studies will be performed to determine the role of the PVN and other CNS sites identified in Specific Aim 1 in the kappa- mediated effects on urine flow, renal sodium excretion and RSNA. (grantome.com)

The technique uses energy targeted to the renal nerves to modulate the sympathetic signalling between the kidneys and brain to reduce blood pressure. (cardiovascularnews.com)

The department offers a nurturing environment for career development, a stimulating community of several kidney and cardiovascular research labs, weekly conferences and seminars of interest. (northwestern.edu)

The primary outcome was the time from randomization to the first occurrence of a composite of major adverse cardiovascular events (MACE). (endocrinologyadvisor.com)

Else van den Berg investigated the dietary habits of a large cohort of renal transplant recipients and the association of several nutrients with cardiovascular risk factors. (rug.nl)
However, whether a reduction in these patients' UACR is associated with a reduction in the risk of future cardiovascular and renal events in those treated with a GLP-1 RA had not yet been established. (endocrinologyadvisor.com)
These findings indicated that a reduction in UACR in a 1-year period predicts a reduced risk for major cardiovascular and renal outcomes. (endocrinologyadvisor.com)
30%) than placebo, a reduction in UACR without liraglutide was still associated with a decreased risk for MACE and renal outcomes. (endocrinologyadvisor.com)
A 10% increase in TTR through 6 months was associated with significant risk reductions in major cardiovascular events from 6 to 36 months. (univr.it)
In the SPYRAL HTN-ON MED pilot study, at three years, blood pressure reductions with the Symplicity blood pressure procedure were present throughout the day and night, including the high-risk zone in the late night and early morning period, which is usually associated with increased risk for stroke and cardiovascular events. (medtronic.com)

The Dublin, Ireland-based company's goal was to present data from the ongoing SPYRAL HTN-ON MED clinical study of its Symplicity Renal Denervation System at the 2021 Transcatheter Cardiovascular Therapeutics Conference (TCT), but that presentation hinged on an interim look at the data by an independent monitoring board. (mddionline.com)

CONCLUSIONS: Postoperative renal failure after p-AAAs repair is still a major concern although perfusion techniques and organ protection are important to reduce its frequency. (minervamedica.it)
Thus, stroke, cardiac failure and renal failure further fuel the vicious cycle of ill-health and poverty. (who.int)
8 However, the deaths due to renal cell carcinoma are driven by the failure of systemic treatments in metastatic (later stage) patients. (ahrq.gov)

To date the clinical programme has completed two randomised, sham-controlled trials, one involving the use of renal denervation in the presence of antihypertensive medications-the SPYRAL HTN-ON MED study-and another investigating the procedure in the absence of medications-the SPYRAL HTN-OFF MED Pivotal trial. (cardiovascularnews.com)
A short video describes the mechanism of action for the Symplicity procedure, also known as renal denervation. (medtronic.com)

Crucially, as more evidence about the safety and efficacy of renal denervation emerges from clinical trials, new guidance in Europe raises the prospect that more patients could have this treatment available. (cardiovascularnews.com)
Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of-concept randomised trial. (medtronic.com)

Patients during dialysis, Kidney patient on his regular visit to the renal dialysis ward of a London hospital where he is connected to a hemodialysis machine which essentially cleans his blood of waste products and toxins. (endocrinologyadvisor.com)

Swimming training improves cardiovascular autonomic dysfunctions and prevents renal damage in rats fed a high-sodium diet from weaning. (bvsalud.org)
An exercise -dependent reduction in blood pressure was associated with decreased CSF [Na+ ], sympathetically driven vasomotor tonus and renal fibrosis indicating that the anti-hypertensive effects of swimming training in rats fed a high- sodium diet might involve neurogenic mechanisms regulated by sodium levels in the CSF rather than changes in blood volume . (bvsalud.org)
CSF [Na+ ] levels were higher in sedentary HS rats but were reduced by ST. Our findings showed that ST effectively normalised BP of HS rats , independent of its effects on hydro-electrolytic balance, which might involve neurogenic mechanisms regulated by Na+ levels in the CSF as well as renal protection . (bvsalud.org)

Altogether, this study shows that with healthier foods, a large health benefit could be gained in renal transplant recipients. (rug.nl)
In this project, NIOSH researchers have an ongoing collaboration with the State University of New York at Buffalo to study the effects of policing and occupational stress on early (subclinical) markers of cardiovascular health. (cdc.gov)
Medtronic previously noted in a regulatory filing with the U.S. Securities Exchange Commission that if the primary endpoint had achieved statistical significance at the time of that interim data analysis in late October, the company would have closed enrollment on the renal denervation study early. (mddionline.com)

Within this framework, renal transplant recipients are counselled shortly after transplantation to improve their dietary habits. (rug.nl)

The ability of antioxidant enzymes to reduce or inhibit the effects of ROS may allow the cardiovascular system to adapt to acute COV exposures. (cdc.gov)
However, sub-chronic exposures may result in longer-lasting negative health consequences on the cardiovascular system. (cdc.gov)
Research Question: What are the central nervous system mechanisms and pathways responsible for the kappa opioid mediated renal effects? (grantome.com)
Watch a short animation that explains the mechanism of action for RF renal denervation with the Symplicity Spyral system. (medtronic.com)
The parasympathetic and sympathetic nervous systems also play a key role in the regulation of the cardiovascular system [2] . (physio-pedia.com)

Exposure: Based on the American Heart Association's recommendations for cardiovascular prevention, a modified healthy lifestyle score was the sum of 4 components addressing use of smoking tobacco, physical activity, diet, and control of systolic. (lu.se)

We have plenty of hypertensive drugs, and we also know that lifestyle modification is able to lower blood pressure," Mahfoud tells Cardiovascular News . (cardiovascularnews.com)
Mahfoud and Tsioufis have been among the leading investigators in studies assessing renal denervation, which has been shown to be capable of lowering blood pressure, as a complementary option to the existing treatments. (cardiovascularnews.com)
BACKGROUND Renal denervation (RDN) has been shown to lower blood pressure (BP), but its effects on cardiovascular events have only been preliminarily evaluated. (univr.it)

Disease36

Mortality16

Insufficiency8

Catheter-based4

Predictor of cardiovascular1

Artery Stenosis10

Diseases4

Hypertension9

Stenosis1

Impairment1

Albuminuria2

Myocardial2

Glomerular2

Arteries2

Denervation procedure1

Therapeutic1

Diabetes4

Serum2

Complications1

Baseline1

Outcomes in patients1

Congestive1

Hepatic2

High cardiovascular risk3

Reduced cardiovascular risk1

Function9

Diagnosis1

Dysfunction1

Excretion3

Modulate1

Kidney and cardiovascular1

Adverse1

Risk6

20211

Failure3

Procedure2

Efficacy2

Dialysis1

Rats3

Study3

Transplantation1

System5

Prevention1

Blood3