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  • homologous
  • Second, the neo-sex chromosome is homologous to the sex chromosomes of mammals, which makes it possible - for the first time - to study mammalian X gene homologs in a novel, avian Z-linked environment where females are the heterogametic sex (ZW), and thus to draw direct parallels over the avian ZW-mammalian XY boundary. (lu.se)
  • conditions
  • It is generally accepted that most aneuploid fetal conditions, such as trisomy 21 Down syndrome, are due to maternal chromosome segregation errors. (warwick.ac.uk)
  • circular chromosomes
  • The decrease in circular rDNA and the degradation of the amplified rDNA population in early embryo development indicated that the small circular molecules are homologous to the rDNA gene cluster, meaning that an abundance of rDNA sequences are not prone to generating circular chromosomes from random events like breakage of ligation. (wikipedia.org)
  • crossover
  • Why has the crossover block come to be extended over most of the chromosome? (genetics.org)
  • Furthermore, the numbers of crossovers and chiasmata are reduced in the absence of TRIP13, and their distribution along the chromosomes is altered, suggesting a role for TRIP13 in aspects of crossover formation and/or control. (uva.nl)
  • To address this limitation, we have collected and mapped the locations of 4829 crossover events occurring on mouse chromosome 11 in 5858 meioses of male and female reciprocal F1 hybrids of C57BL/6J and CAST/EiJ mice. (jax.org)
  • Genetics
  • Plant breeding can be accomplished through many different techniques ranging from simply selecting plants with desirable characteristics for propagation, to methods that make use of knowledge of genetics and chromosomes, to more complex molecular techniques (see cultigen and cultivar). (wikipedia.org)
  • 1991
  • Gill BS, Friebe B, Endo TR (1991) Standard karyotype and nomenclature system for description of chromosome bands and structural aberrations in wheat ( Triticum aestivum ). (springer.com)
  • 1991. dif, a recA-independent recombination site in the terminus region of the chromosome of Escherichia coli. (asmscience.org)
  • locus
  • Dubcovsky J, Luo M, Dvorak J (1995) Differentiation between homoeologous chromosomes 1A of wheat and 1A m of Triticum monococcum and its recognition by the wheat Ph1 locus. (springer.com)
  • replication
  • However, if the polymerases dissociate from the fork (fork collapse) or the fork structure breaks (broken fork), replication restart can proceed either by homologous recombination (HR) or microhomology-primed re-initiation (FoSTeS/MMBIR)4,5. (sussex.ac.uk)
  • As indicated in the mitosis diagram, mitosis is preceded by a round of DNA replication, so that each chromosome forms two copies called chromatids. (wikipedia.org)
  • Grete Kellenberger's major scientific contribution was the discovery that recombination is due to a physical exchange of DNA, and not to selective replication. (wikipedia.org)
  • paternal
  • Five paternal half sib families of German Angus (GA) (n = 428) and six of German Simmental (GS) (n = 378) including dams were genotyped with 11 microsatellites (INRA132, RM033, BM1815, BM1258, BOLA-DRB1, BM1818, BM1905, BM1443, CYP21, CSSM5 and DYMS1) derived from chromosome 23. (unibz.it)
  • roles
  • Discovery of the molecular structure of telomeres, telomerase enzyme, the templating role of telomerase RNA and their roles in cellular senescence and chromosome healing (for which a Nobel Prize was won). (wikipedia.org)
  • Genomic
  • Additionally, chromosome 19, which contains Pten, was also selectively deleted in medulloblastoma arising after disruption of HR. Thus, our data highlight the preeminence of Ptch1 as a tumor suppressor in cerebellar granule cells and reveal other genomic events central to the genesis of medulloblastoma. (pnas.org)
  • Polytenization arises with under- or overamplification of some genomic regions, creating polytene chromosomes. (wikipedia.org)
  • Cells
  • This allows the selection of single cells that have incorporated the DNA construct into their own chromosomes. (jrank.org)
  • yeast
  • We focus our research on meiotic recombination, mainly working with the model plant Arabidopsis thaliana and to some extent with the yeast Saccharomyces cerevisiae . (oeaw.ac.at)
  • differences
  • Significant differences in recombination rates between GA and GS could be demonstrated for the marker intervals INRA132-CSSM5, CYP21-BOLA-DRB1 and BOLA-DRB1-BM1818. (unibz.it)
  • gene of interest
  • The ability to target DNA constructs to particular locations in chromosomes is a very powerful tool because it allows the modification of more or less any gene of interest, in more or less any way desired. (jrank.org)
  • contrast
  • In contrast, another pedigree following colorblindness and the slightly different B form of hemophilia, which also arises from a mutation on the X chromosome, revealed a different inheritance pattern. (docplayer.net)
  • In contrast to the sexual diploids, the pairing of chromosomes at metaphase I in triploid apomicts is strongly reduced. (wikipedia.org)
  • analysis
  • Extreme size variations of the alpha-satellite I blocks transmitted in these families and deduced from quantitative FISH analysis are not correlated with the inter-individual variations of recombination activity observed in the peri-centromeric region. (oup.com)
  • This chromosome was chosen for its medium size and high gene density and provided a comparison with our previous analysis of recombination on the longest mouse chromosome 1. (jax.org)
  • She developed the technique for visualizing maize chromosomes and used microscopic analysis to demonstrate many fundamental genetic ideas. (wikipedia.org)