Recombinant prostatic secretory proteins. Medical search. Frequent questions

In addition, we observed that NT5E was extensively co-localized with Prostatic acid phosphatase (PAP, also known as ACPP, Fluoride-resistant acid phosphatase or thiamine monophosphatase) in nociceptive neurons. (biomedcentral.com)
Functional amyloid in Homo sapiens: Intralumenal domain of melanocyte protein PMEL Peptide/protein hormones stored as amyloids within endocrine secretory granules Receptor-interacting serine/threonine-protein kinase 1/3 (RIP1/RIP3) Fragments of prostatic acid phosphatase and semenogelins Functional amyloid in other organisms: Curli fibrils produced by E. coli, Salmonella, and a few other members of the Enterobacteriales (Csg). (wikipedia.org)
The follow-up vaccine CV9104 including the additional antigens prostatic acid phosphatase (PAP) and Muc1 is currently being tested in a randomized phase IIb trial to assess the clinical benefit induced by this new vaccination approach. (biomedcentral.com)

In brief: One of the most commonly prescribed benign prostatic hyperplasia (BPH) pharmacotherapies, the alpha1-adrenergic blocker tamsulosin, is frequently discontinued, especially by younger patients due to ejaculatory disorders, often without feedback to the attending physician. (bvsalud.org)

Ab-3 shows no reaction with a variety of normal tissues .CEA is not found in benign glands, stroma, or malignant prostatic cells. (samatashkhis.com)

To overcome these toxicity concerns, we purified and characterized ( in vitro and in vivo ) a secretory version of recombinant mouse NT5E. (biomedcentral.com)
This protein was produced in an in vitro wheat germ expression system that should preserve correct conformational folding that is necessary for biological function. (novusbio.com)
Gene technology-based antimetabolite design: The use of an in vitro protein expression system to facilitate antimetabolite design for virally-induced human diseases and malignant conditions. (ntu.ac.uk)

Ecto-5'-nucleotidase (NT5E) is a glycosyl phosphatidylinositol (GPI)-anchored membrane protein that catalyzes the hydrolysis of extracellular AMP to adenosine [ 1 ]. (biomedcentral.com)
The chemical or biochemical addition of carbohydrate or glycosyl groups to other chemicals, especially peptides or proteins. (lookformedical.com)

The BOB.1, OBF.1, OCA-B (now called BOB.1 / OBF.1) is a 35 kD protein encoded by a gene located on chromosome 11q23.1. (samatashkhis.com)

Any of the enzymatically catalyzed modifications of the individual AMINO ACIDS of PROTEINS, and enzymatic cleavage or crosslinking of peptide chains that occur pre-translationally (on the amino acid component of AMINO ACYL TRNA), co-translationally (during the process of GENETIC TRANSLATION), or after translation is completed (POST-TRANSLATIONAL PROTEIN PROCESSING). (lookformedical.com)

An unusual secondary structure named α sheet has been proposed as the toxic constituent of amyloid precursor proteins, but this idea is not widely accepted at present. (wikipedia.org)

This antibody detects both active and inactive forms of Caspase-3 protein. (samatashkhis.com)
anti-human Caspase 3 rabbit polyclonal antibody purified from rabbit anti-serum by Protein A chromatography. (samatashkhis.com)
The MUC5AC Antibody detects for mucin 5AC (MUC5AC), a secretory-type mucin found in columnar mucous cells of surface gastric epithelium, in goblet cells of the fetal, and in precancerous colon, but is not found in normal colon cells. (neuromics.com)

Pathogenic amyloids form when previously healthy proteins lose their normal structure and physiological functions (misfolding) and form fibrous deposits within and around cells. (wikipedia.org)
To define the localization of WDFY2 in the endocytic pathway, we transiently transfected hTERT-RPE1 cells with green flourescent protein (GFP)-WDFY2 and performed structured illumination microscopy (SIM) together with APPL1 and EEA1 visualized with antibodies (Fig. 1a ). (nature.com)

1 The physiologicalrole of these proteins is unclear but a number of potential biological functions have been postulated, including regulationof secretory granule formation and produc- tion ofbioactivepeptidesthroughproteolyticprocessing. (123dok.net)
It is likely that endostatin has a number of biological functions mediated by different regions of the protein. (justia.com)

Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins (Probable). (neobiotechnologies.com)

To date, 37 human proteins have been found to form amyloid in pathology and be associated with well-defined diseases. (wikipedia.org)

A genetically heterogeneous group of heritable disorders resulting from defects in protein N-glycosylation. (lookformedical.com)

BOB.1 mission is to increase transcriptional activity of such proteins. (samatashkhis.com)

GvpA, forming the walls of particular Gas vesicles, i.e. the buoyancy organelles of aquatic archaea and eubacteria Fap fibrils in various species of Pseudomonas Chaplins from Streptomyces coelicolor Spidroin from Trichonephila edulis (spider) (Spider silk) Hydrophobins from Neurospora crassa and other fungi Fungal cell adhesion proteins forming cell surface amyloid regions with greatly increased binding strength Environmental biofilms according to staining with amyloid specific dyes and antibodies. (wikipedia.org)
Hamilton: B. C. Decker Inc.). A number of anti-angiogenic activities have been reported for this protein, such as inhibition of endothelial cell proliferation, migration, and tube formation. (justia.com)
BOB.1 from "B cell binding Octamer protein 1 "is a specific coactivator of transcription factors Oct-1 and Oct-2 of B lymphocytes. (samatashkhis.com)
Most benefits were demonstrated in cyclin dependent-kinase 12 ( CDK12) mutated cell lines when treated with anti-programmed cell death protein 1 (PD1) therapy. (bjbms.org)

While it is possible that this protein could display some level of activity, the functionality of this protein has not been explicitly measured or validated. (novusbio.com)

The International Society of Amyloidosis classifies amyloid fibrils and their associated diseases based upon associated proteins (for example ATTR is the group of diseases and associated fibrils formed by TTR). (wikipedia.org)

These protein misfolding and deposition processes disrupt the healthy function of tissues and organs. (wikipedia.org)
Here, we have studied the function of WDFY2, a cytosolic protein that has been described to reside on endocytic vesicles close to the plasma membrane 6 . (nature.com)

As emphasized in a recent review by Colgan and colleagues, this lack of a reliable source of purified protein has hindered studies with NT5E [ 2 ]. (biomedcentral.com)

Seminalplasmin, the major basic protein of bull seminal plasma, is a secretory protein of the seminal vesicles. (mpg.de)
Major seminal plasma proteins are secretory proteins from the male sex accessory glands, such as the SEMINAL VESICLES and the PROSTATE . (bvsalud.org)

This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. (cancerindex.org)
Annexin A1 (ANXA1), the first member of the annexin superfamily, is a Ca 2+ -dependent phospholipid-binding protein with two distinct regions: a variable N-terminal domain and a conserved C-terminal domain [ 10 ]. (biomedcentral.com)
Bone-growth regulatory factors that are members of the transforming growth factor-beta superfamily of proteins. (lookformedical.com)

A monoclonal antibody generated against a recombinant peptide fragment of the B3 domain of carcinoembryonic antigen reacts with intact carcinoembryonic antigen. (mpg.de)
TSG101 antibody [4A10] is a well-validated and highly cited mouse monoclonal antibody that detects TSG101, a protein of 390 amino acids and a predicted molecular weight of 44 kDa that is a core constituent of the ESCRT-I complex. (genetex.com)

Characterization by cDNA cloning of two new human protein kinases: Evidence by sequence comparison of a new family of mammalian protein kinases. (mpg.de)
A microtubule subunit protein found in large quantities in mammalian brain. (lookformedical.com)

Characterization by cDNA cloning of the messenger-RNA of human ribosomal protein L8. (mpg.de)
The complete cDNA coding sequence for the mouse CDEI binding protein. (mpg.de)
Characterization by cDNA cloning of the mRNA of a highly basic human protein homologous to the yeast ribosomal protein YL41. (mpg.de)

HN - 2006(1981) BX - Actin-Capping Proteins MH - Actin Depolymerizing Factors UI - D051339 MN - D5.750.78.730.212 MN - D12.776.220.525.212 MS - A family of low MOLECULAR WEIGHT actin-binding proteins found throughout eukaryotes. (nih.gov)
The vesicle associated membrane proteins (VAMP) or synaptobrevins are calcium binding proteins specific to eukaryotes. (novusbio.com)

The potential use of prostatic secretory protein of 94 amino acid residues (PSP94) as a serum marker for prostatic tumor. (mpg.de)
Amino acids 167-374 of TSG101 protein expressed in E. coli. (genetex.com)
Proteins containing a region of conserved sequence, about 200 amino acids long, which encodes a particular sequence specific DNA binding domain (the T-box domain). (lookformedical.com)

The founding member of the nodal signaling ligand family of proteins. (lookformedical.com)

AN - coordinate IM with ADENOMA (IM) HN - 2006 BX - Corticotroph Adenoma BX - Pituitary Adenoma, ACTH-Secreting BX - Pituitary Corticotropin-Secreting Adenoma MH - Actin Capping Proteins UI - D051344 MN - D5.750.78.730.32 MN - D12.776.220.525.32 MS - Actin capping proteins are cytoskeletal proteins that bind to the ends of ACTIN FILAMENTS to regulate actin polymerization. (nih.gov)
HN - 2006(1981) BX - Cofilins MH - Actin-Related Protein 2 UI - D051377 MN - D5.750.78.730.246.500 MN - D12.776.220.525.246.500 MS - A PROFILIN binding domain protein that is part of the Arp2-3 complex. (nih.gov)
HN - 2006(1998) MH - Actin-Related Protein 2-3 Complex UI - D051376 MN - D5.750.78.730.246 MN - D12.776.220.525.246 MS - A complex of seven proteins including ARP2 PROTEIN and ARP3 PROTEIN that plays an essential role in maintenance and assembly of the CYTOSKELETON. (nih.gov)
Arp2-3 complex binds WASP PROTEIN and existing ACTIN FILAMENTS, and it nucleates the formation of new branch point filaments. (nih.gov)
HN - 2006 BX - Arp2-3 Complex MH - Actin-Related Protein 3 UI - D051378 MN - D5.750.78.730.246.750 MN - D12.776.220.525.246.750 MS - A component of the Arp2-3 complex that is related in sequence and structure to ACTIN and that binds ATP. (nih.gov)

GvpA, forming the walls of particular Gas vesicles, i.e. the buoyancy organelles of aquatic archaea and eubacteria Fap fibrils in various species of Pseudomonas Chaplins from Streptomyces coelicolor Spidroin from Trichonephila edulis (spider) (Spider silk) Hydrophobins from Neurospora crassa and other fungi Fungal cell adhesion proteins forming cell surface amyloid regions with greatly increased binding strength Environmental biofilms according to staining with amyloid specific dyes and antibodies. (wikipedia.org)

[ 127 ] They compared hypermethylation of circulating cell DNA from prostate cancer patients with (Group 1, n =20) and without (Group 2, n = 22) disease progression and age-matched controls (benign prostatic hyperplasia, Group 3, n = 22). (medscape.com)
The protein has proapoptotic activities in prostate and bladder cancer cells. (cancerindex.org)
Species- and organ-specificity of secretory proteins derived from human prostate and seminal vesicles. (mpg.de)

Proteins obtained from various species of Xenopus. (lookformedical.com)
Many of the proteins in this species have been the subject of studies involving basic embryological development (EMBRYOLOGY). (lookformedical.com)

An unusual secondary structure named α sheet has been proposed as the toxic constituent of amyloid precursor proteins, but this idea is not widely accepted at present. (wikipedia.org)
A human amyloid precursor-like protein is highly homologous to a mouse sequence-specific DNA-binding protein. (mpg.de)
The gene for the amyloid precursor-like protein APLP2 is assigned to human chromosome 11q23-q25. (mpg.de)

To date, 37 human proteins have been found to form amyloid in pathology and be associated with well-defined diseases. (wikipedia.org)
The International Society of Amyloidosis classifies amyloid fibrils and their associated diseases based upon associated proteins (for example ATTR is the group of diseases and associated fibrils formed by TTR). (wikipedia.org)
Functional amyloid in Homo sapiens: Intralumenal domain of melanocyte protein PMEL Peptide/protein hormones stored as amyloids within endocrine secretory granules Receptor-interacting serine/threonine-protein kinase 1/3 (RIP1/RIP3) Fragments of prostatic acid phosphatase and semenogelins Functional amyloid in other organisms: Curli fibrils produced by E. coli, Salmonella, and a few other members of the Enterobacteriales (Csg). (wikipedia.org)

Here, Western blot and qRT-PCR analysis revealed that TPX2 at both mRNA and protein levels was up-regulated in bladder carcinoma tissues compared to their paired adjacent normal tissues. (cancerindex.org)

To search for other proteins that may undergo RAT, we performed a bioinformatics analysis to identify proteins that contain a GXXXN motif in their first transmembrane helix. (elifesciences.org)
Tripartite Motif Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uchicago.edu)
This graph shows the total number of publications written about "Tripartite Motif Proteins" by people in this website by year, and whether "Tripartite Motif Proteins" was a major or minor topic of these publications. (uchicago.edu)
Below are the most recent publications written about "Tripartite Motif Proteins" by people in Profiles. (uchicago.edu)

8. Modifications in adenoviral coat fiber proteins and transcriptional regulatory sequences enhance transgene expression. (nih.gov)

However, the afferent prostatic blood flow does not account for the specificity of PCa metastatic lesion incidence within the spine as only 5C10% of prostatic blood flow is directed towards the spinal cord [10], [11]. (ap26113.com)

In utero exposure to vinclozolin was insufficient to perturb prostatic development and branching, although expression of androgen receptor and mesenchymal fibroblast growth factor-10 was down-regulated. (nih.gov)
Prostatic inflammation was associated with phosphorylation and nuclear translocation of nuclear factor-kappa B (NFκB) and postpubertal activation of proinflammatory NFκB-dependent genes, including the chemokine interleukin-8 and the cytokine transforming growth factor-β1. (nih.gov)
VAMPs, along with synaptosomal associated protein of 25 kDa (SNAP-25) and syntaxin, form the core complex of soluble NSF attachment protein receptor (SNARE) proteins that interact with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and alpha-SNAP. (novusbio.com)

Proteins encoded by homeobox genes (GENES, HOMEOBOX) that exhibit structural similarity to certain prokaryotic and eukaryotic DNA-binding proteins. (lookformedical.com)

The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins. (lookformedical.com)

Annexin A1 (ANXA1), a Ca 2+ -regulated phospholipid-binding protein, has been demonstrated to be implicated in the progression and prognosis of many cancers. (biomedcentral.com)

The targeting protein for Xenopus kinesin-like protein 2 (TPX2) is associated with the metastasis and prognosis of bladder cancer. (cancerindex.org)
There also appears to be an association between cancer risk and the associated IGF binding proteins (IGFBP). (crenolanibinhibitor.com)
Advance your cancer research with our high-quality Recombinant Human SRC protein, also known as Proto-oncogene tyrosine-protein kinase Src and Proto-oncogene c-Src. (cusabio.com)
Available in both liquid and lyophilized powder forms, our Recombinant Human SRC protein is ready to support your cancer research endeavors. (cusabio.com)

2BECFP cells exhibit marked binding affinity to laminin relative to LNECFP controls, and recombinant beta-2 ectodomain elicits more binding events to laminin than BSA control. (ap26113.com)
Purified recombinant fibulin-5 with either mutation showed reduced affinity for tropoelastin in solid-phase binding assays. (nih.gov)

TSG101 antibody [4A10] detects TSG101 protein at cytoplasm by immunohistochemical analysis. (genetex.com)
WB: Detects a 13 kDa protein (predicted MW 12 kDa). (novusbio.com)

Prostatic innervation is essential for proper growth, development, and secretory function [12]. (ap26113.com)
Many of these proteins have been the subject of scientific investigations in the area of MORPHOGENESIS and development. (lookformedical.com)
Proteins that are preferentially expressed or upregulated during FETAL DEVELOPMENT. (lookformedical.com)
Homeodomain proteins are involved in the control of gene expression during morphogenesis and development (GENE EXPRESSION REGULATION, DEVELOPMENTAL). (lookformedical.com)

The same mutation triggered an endoplasmic reticulum (ER) stress response, as indicated by the strong co-localization of this mutant protein with folding chaperones in the ER, including calreticulin, immunoglobulin-binding protein and protein disulfide isomerase, and by increased rates of apoptosis in patient fibroblasts. (nih.gov)

G protein-coupled receptors (GPCRs) are a family of proteins containing seven transmembrane helices, with the N- and C-terminus of the protein located at the extracellular space and cytosol, respectively. (elifesciences.org)
We have recently analyzed the topology of a transmembrane protein called TM4SF20 (transmembrane 4 L6 family member 20). (elifesciences.org)
A protein family defined by the presence of three ZINC FINGER domains, one of which is a RING FINGER DOMAIN, a coiled-coil region, and a highly variable C-terminal region. (uchicago.edu)

What does this gene/protein do? (cancerindex.org)
Human glioma pathogenesis-related protein 1 (GLIPR1) is a p53 target gene with antitumor activity. (cancerindex.org)
The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. (genetex.com)

Scope includes mutations and abnormal protein expression. (cancerindex.org)

Our Recombinant Human SRC protein is produced using a robust E.coli expression system, providing a consistent and reliable source for your research needs. (cusabio.com)

Proteins found in SEMEN . (bvsalud.org)

Saccharomyces-yogurt showed high antioxidant activity, phenolic acids, and crude protein content. (bvsalud.org)

It is expressed at higher levels than ARP2 PROTEIN and does not contain a PROFILIN binding domain. (nih.gov)

13. Increased glia-specific transgene expression with glial fibrillary acidic protein promoters containing multiple enhancer elements. (nih.gov)

Nodal protein was originally discovered in the region of the mouse embryo primitive streak referred to as HENSEN'S NODE. (lookformedical.com)

Centrosomal protein TRIM43 restricts herpesvirus infection by regulating nuclear lamina integrity. (uchicago.edu)

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. (cusabio.com)

15. Recombinant adenovirus administration in rat peritoneum: endothelial expression and safety concerns. (nih.gov)

Pathogenic amyloids form when previously healthy proteins lose their normal structure and physiological functions (misfolding) and form fibrous deposits within and around cells. (wikipedia.org)

These membrane associated proteins play a key role in the regulation of vesicle membrane fusion with the plasma membrane. (novusbio.com)

Western Blot: VAMP3/Cellubrevin Antibody [NB300-510] - Analysis of recombinant rat VAMP-3. (novusbio.com)
This analysis revealed that ~100 transmembrane proteins, most of which are GPCRs, met our searching criteria ( Table 1-source data 1 ). (elifesciences.org)

The antiviral activities of TRIM proteins. (uchicago.edu)

Anatomy1

Diseases3

Chemicals and Drugs2

Acid phosphatase3

Hyperplasia1

Benign1

Vitro3

Glycosyl2

Gene1

Peptide1

Constituent1

Antibody3

Cells2

Biological2

PROCESSING1

Human1

Disorders1

Increase1

Cell4

Activity1

Group1

Function2

Review1

Seminal plasma2

Superfamily3

Monoclonal antibody2

Mammalian2

CDNA3

Eukaryotes2

Amino3

Ligand1

Actin5

Antibodies1

Prostate3

Species2

Precursor3

Amyloid3

MRNA1

Motif4

Regulatory1

Specificity1

Factor3

Genes1

Dimer1

Progression1

Cancer4

Affinity2

Detects2

Development4

Apoptosis1

Family3

Gene3

Scope1

Human1

Found1

High1

Levels1

Specific1

Mouse1

Nuclear1

Stability1

Expression1

Normal1

Play1

Analysis2

Activities1