Recipients liver transplantation. Medical search. Frequent questions

The aim of this study is to report and analyze for the first time incidence and outcomes of HT in LT recipients, as well as to suggest a management strategy. (physiciansweekly.com)
Trends and Outcomes of Liver Transplantation Among Older Recipients in" by Kenji Okumura, Joon Sub Lee et al. (touro.edu)
CONCLUSION: While there is a higher risk of graft failure in older recipient population, age alone should not be a contraindication for LT. Careful selection of donors and recipients along with optimal management of risk factors during the postoperative period are necessary to maximize the transplant outcomes in this population. (touro.edu)
Julie Doberne, MD, PhD, with the Department of Cardiovascular and Thoracic Surgery, Duke University, in Durham, North Carolina, has researched survival outcomes of heart transplantation for HIV-positive recipients in comparison with outcomes for HIV-negative recipients. (medscape.com)
Aragon Pinto C, Iyer VN , Albitar HAH, Anderson A, Cajigas H, Simonetto DA, Krowka MJ, DuBrock HM, Gallo de Moraes A. Outcomes of liver transplantation in patients with hepatopulmonary syndrome in the pre and post-MELD eras: A systematic review. (mayo.edu)
National trends and long-term outcomes of liver transplant for alcohol-associated liver disease in the United States. (thieme-connect.com)
Cannabis use is not associated with adverse outcomes following liver transplantation, according to data published in the journal Clinical Transplantation . (norml.org)
Researchers from the Dumont-UCLA Transplant and Liver Cancer Center at the David Geffen School of Medicine assessed the impact of pre and post-transplant marijuana use on liver transplant outcomes in a cohort of 900 patients. (norml.org)
Investigators reported, "[T]here were no statistical differences in post-operative outcomes, including patient/graft survival and post-LT [liver transplant] complications in pre- or post-LT users. (norml.org)
Some clinicians believe pancreas after kidney (PAK) transplantation has inferior outcomes compared to simultaneous kidney-pancreas (SPK) transplantation. (unos.org)
The special issue also presents new data on the long-term outcomes of living pancreas donors and the safety systems established for hematopoietic stem cell transplant donors. (sciencedaily.com)
Impact of Donor Age on Allogeneic Hematopoietic Cell Transplantation Outcomes in Older Adults with Acute Myeloid Leukemia. (stembook.org)
Inferior Outcomes with Cyclosporine and Mycophenolate mofetil after Myeloablative Allogeneic Hematopoietic Cell Transplantation. (stembook.org)
HealthDay News) - Outcomes are encouraging for the first 3 living kidney donors with HIV, according to research published online in The Lancet Regional Health: Americas . (renalandurologynews.com)
All of these conditions lead to poor outcomes during or after transplantation. (msdmanuals.com)
Outcomes and factors affecting survival were analyzed in 5347 consecutive OLTs performed in 3752 adults and 822 children between 1984 and 2012, including comparisons of recipient and donor characteristics, graft and patient outcomes, and postoperative morbidity before (n = 3218) and after (n = 2129) implementation of the MELD allocation system. (escholarship.org)
Although several countries have introduced compulsory registration of transplant procedures and some voluntary registries also exist, there is no comprehensive system to collect data on the different types of transplantation and their outcomes. (who.int)
The role of preoperative optimization of the nutritional status on the improvement of short-term outcomes after liver transplantation? (bvsalud.org)
It also remains unclear if preoperative nutritional interventions have benefits to post-transplant outcomes for transplant recipients. (bvsalud.org)

Transplantation;106(8): 1609-1614, 2022 08 01. (bvsalud.org)
In 2022, 9528 liver transplantations were performed in the United States. (medscape.com)

From the initiation of the laparoscopic donor nephrectomy programme at our institution in November 1998 until February 2002, we performed 71 living donor kidney transplants (69 kidneys procured laparoscopically and two procured by open donor nephrectomy after failed laparoscopic approach). (elsevierpure.com)
Doctors do liver transplants when other treatment cannot keep a damaged liver working. (medlineplus.gov)
The need for liver transplants currently far eclipses the supply of available donor organs. (medscape.com)
Despite a steady increase of more than 30% in liver transplants per year since 2012, many patients continue to die while awaiting a life-saving transplant. (medscape.com)
For more than 40 years, Montefiore's physicians have performed successful liver transplants worldwide. (montefiore.org)
While living-donor liver transplantation (LDLT) accounts for less than five percent of liver transplants in the United States and Europe, it has become the principal form of liver transplantation worldwide. (sciencedaily.com)
Two months later, researchers at Johns Hopkins performed the first liver and kidney HIV-to-HIV transplants. (positivelyaware.com)
Our one-year patient survival rates for lung transplants exceed the national average, placing us among the nation's best transplant centers by the Scientific Registry of Transplant Recipients (SRTR). (ucsd.edu)
In pediatric transplants, female adult living donors are more common, while male recipients are more common in low- and middle-income settings. (bmj.com)
Annually, more than 500 transplants in the US come from living donors, who can live without their right lobe (in adult-to-adult transplantation) or the lateral segment of their left lobe (in adult-to-child transplantation). (msdmanuals.com)
The evolution of liver transplantation during 3 decades: analysis of 5347 consecutive liver transplants at a single center. (escholarship.org)
In many of the clusters of rabies transmission through organ transplants, identification of the cause was complicated by delayed diagnosis or misdiagnosis due to the rarity of the disease, geographic distance separating transplant recipients, and lack of prompt recognition and reporting systems. (cdc.gov)
After approval by the Research Ethics Committee for the Santa Casa de Misericórdia de São Paulo, this study evaluated 33 prospective patients who were candidates for liver transplants and had been receiving treatment in a dentistry department for patients with special needs, during 3 years, according to the indication/medical records maintained by the liver transplant team. (bvsalud.org)

Data concerning 7130 consecutive adult liver and liver-kidney transplant recipients were retrospectively collected from ten Transplantation Centers' institutional databases, over a 10-year period. (physiciansweekly.com)
Expansion of the use of split livers involves increasing cooperation between centers and expanding institutional experience with these techniques. (medscape.com)
These were forwarded with the donated organs to the various transplantation centers. (cdc.gov)
The donor's kidneys, heart, and liver were removed and transported to other medical centers for transplantation. (cdc.gov)

ICG ﬂuorescence cholangiography might be helpful to reduce biliary complications after LDLT in both donors and recipients. (docksci.com)
Recently, a novel ﬂuorescent intraoperative cholangiography technique for cholecystectomy using indocyanine green (ICG) has been used, and in 2009 we started using ICG ﬂuorescence cholangiography in LDLT donors who underwent right or left hepatectomy [16], because appropriate cutting line of the bile duct in the donor operation is one of the key issues to prevent biliary complications in both donors and recipients after LDLT. (docksci.com)
The data were collected from our records in the LT unit and written informed consents were obtained from both donors and recipients regarding operations and researches. (wjgnet.com)
The approach to evaluation and follow-up provides additional transplantation options to benefit both potential donors and recipients with HIV," the authors write. (renalandurologynews.com)

The first recipient was a 64-year-old man who had hepatocellular carcinoma and underwent liver transplantation. (cdc.gov)
Dr. Sanchez has served as the principal investigator and co-program director of a National Cancer Institute-funded study comparing multiphase contrast-enhanced CT and MRI for diagnosis of hepatocellular carcinoma, the most common type of liver cancer, and for liver transplant allocation. (mayo.edu)
These criteria plus the absence of extrahepatic and major vessel involvement satisfy the Milan criteria, used to assess suitability of liver transplantation for patients who have cirrhosis and hepatocellular carcinoma. (msdmanuals.com)

As of October 24, 2023, according to the Organ Procurement and Transplantation Network , 10,227 patients were awaiting a liver transplant. (medscape.com)

Perioperative Delta Sodium and Post-Liver Transplant Neurological Complications in Liver Transplant Recipients. (bvsalud.org)
Hyponatremia before liver transplant (LT) increases risk of post-LT neurological complications in patients with decompensated cirrhosis , but it is unknown to what extent change in sodium from pre- to post-LT influences risk of central nervous system (CNS) sequelae. (bvsalud.org)
Adult LT recipients with higher perioperative delta sodium shifts displayed a higher risk of post-LT CNS complications , even after adjusting for pre-LT sodium . (bvsalud.org)
LT recipients, even those with pre-LT hyponatremia , may benefit from maintenance of stable serum sodium levels to minimize post-LT CNS complications . (bvsalud.org)
Biliary complications in 108 consecutive recipients with duct-to-duct biliary reconstruction in living-donor liver transplantation. (docksci.com)
Biliary complications remain the leading cause of postoperative complications after living-donor liver transplantation (LDLT) in patients undergoing duct-to-duct choledochocholedochostomy. (docksci.com)
However, since the introduction of ICG ﬂuorescence cholangiography, we have not encountered any biliary complications in either donors or recipients. (docksci.com)
In other words, biliary complications directly associated with surgical procedures should be avoided or overcome through innovative surgical techniques and understanding of liver anatomy [13]. (docksci.com)
Epstein-Barr virus (EBV) primary infection and/or reactivation are suggested to play a significant role in the incidence of post-transplantation lymphoproliferative disorders (PTLD) and some other complications in immunocompromised patients, especially organ recipients. (govaresh.org)
Liver biopsy on POD 7 showed no evidence of rejection, biliary complications or drug-induced liver injury. (cdc.gov)
Approximately 30 to 40 percent of recipients will experience some complications within three months of transplant. (montefiore.org)
Patients with a very high Model for End-Stage Liver Disease (MELD) score at transplant and patients with acute liver failure are at higher risk for complications and a longer recovery, and their overall survival rates are also lower. (montefiore.org)
Disadvantages to the donor include mortality risk of 1/600 to 700 (compared with 1/3300 in living-donor kidney transplantation) and complications (eg, bile leakage, bleeding) in up to one fourth. (msdmanuals.com)
A few livers come from deceased, non-heart-beating donors (called donation-after-cardiac-death [DCD] donors), but in such cases, bile duct complications develop in up to one third of recipients because the liver had been damaged by ischemia before donation. (msdmanuals.com)
Where appropriate medical care is available, the risks associated with live kidney donation are low but not negligible - in addition to operative complications, they include such long-term risks as failure of the remaining kidney. (who.int)
Aim: To evaluate the invasive dental procedures for removing dental foci performed in patients scheduled for liver transplantation and its accompanying complications. (bvsalud.org)
Methods: The medical records of 33 preliver transplant recipients who were undergoing invasive dental procedures were reviewed, including their laboratory tests, special handling needs and resulting complications. (bvsalud.org)
Conclusions: Surgical intervention to remove dental foci in liver disease patients requires careful clinical evaluation, laboratory tests, knowledge and skills in the use of local and systemic hemostatic procedures, and a partnership approach between dentists and physicians, in order to reduce the risk of complications. (bvsalud.org)
This research aimed at evaluating invasive dental procedures for removing dental foci in patients scheduled for liver transplantation along with any accompanying complications. (bvsalud.org)
Because injection drug use is the most commonly reported risk factor for hepatitis C,() providers caring for recipients of organs from donors who are HCV-seropositive or recently injected drugs should maintain awareness of infectious complications of injection drug use and monitor recipients accordingly (2). (cdc.gov)

abstract = "Background: Laparoscopic live donor nephrectomy is becoming increasingly popular as it has been shown to minimize donor morbidity, length of hospital stay and length of time to return to work. (elsevierpure.com)
abstract = "In living donor liver transplantation, the safety of the donor operation is the highest priority. (elsevierpure.com)

INCE Wachs et al ﬁrst reported duct-to-duct direct biliary reconstruction for living-donor liver transplantation (LDLT) in 1998 [1], duct-to-duct reconstruction has been performed in many institutions. (docksci.com)
There are few reviews concerning the feasibility of using marginal liver grafts in living donor liver transplantation (LDLT). (wjgnet.com)
We reviewed more than 300 articles, summarized new findings, and confirmed that marginal grafts are a feasible option for expanding options for patients on liver transplant waiting lists in emergency situations in LDLT ( e.g ., liver failure or hepatic encephalopathy). (wjgnet.com)
The special issue presents the International Liver Transplantation Society guidelines on LDLT, as well as a summary of recent UK guidelines. (sciencedaily.com)
We herein present one case of pediatric living donor liver transplantation (LDLT) combined with spleen-preserving regional total. (koreamed.org)
Replacement of the inferior vena cava (IVC) after concurrent resection of hepatoblastoma-containing liver and retrohepatic IVC is regarded as a feasible option for pediatric living-donor liver transplantation (LDLT). (koreamed.org)

LD kidney transplantation (LDKT) is preferred over DD kidney transplantation (DDKT), because of superior quality kidneys that result in improved patient and graft survival ( 2 ), greater flexibility for transplantation across the ABO ( 3 , 4 ) and HLA ( 5 , 6 ) barriers, and the possibility for kidney exchange ( 7 ) including chains initiated by unspecified donors ( 8 ). (frontiersin.org)
Other individuals have a multitude of the most severe symptoms of end-stage liver disease and a limited chance for survival. (medscape.com)
Recipient survival was best in children with biliary atresia and worst in adults with malignancy. (escholarship.org)
Of 17 recipient and donor variables, era of transplantation, etiology of liver disease, recipient and donor age, prior transplantation, MELD score, hospitalization at time of OLT, and cold and warm ischemia time were independent predictors of survival. (escholarship.org)
Despite increasing acuity in post-MELD era recipients, patient and graft survival continues to improve, justifying the "sickest first" allocation approach. (escholarship.org)
Religiosity associated with prolonged Survival in Liver Transplant Recipients. (bvsalud.org)
[ 2 ] Nevertheless, extended survival was seen in a few patients and included a 3-year-old girl who received a multivisceral transplant (stomach, duodenum, pancreas, small bowel, colon and liver). (medscape.com)
One-year survival has been reported following transplantation of a living-related segment of a donor intestine [ 4 ] and in a 41-year-old woman with short gut syndrome (SGS) secondary to superior mesenteric artery thrombosis. (medscape.com)
[ 5 ] In a series of 6 intestine transplant recipients treated with CsA, the mean survival rate was 25.7 months -- 2 patients surviving for 5.5 and 5 years. (medscape.com)
The introduction of TAC in 1990 improved actuarial graft and patient survival rates following all types of intestine transplantation. (medscape.com)

Cirrhosis is defined histologically as a diffuse hepatic process characterized by fibrosis and conversion of the normal liver architecture into structurally abnormal nodules. (medscape.com)
The progression of liver injury to cirrhosis may occur over several weeks to years. (medscape.com)
Specific medical therapies may be applied to many liver diseases in an effort to diminish symptoms and to prevent or forestall the development of cirrhosis. (medscape.com)
Cases of alcohol-associated liver disease (ALD) are increasing at a steady rate in the United States with more patients presenting with alcohol-associated hepatitis and alcohol-associated cirrhosis. (thieme-connect.com)
Mortality due to cirrhosis and liver cancer in the United States, 1999-2016: observational study. (thieme-connect.com)
Alcohol as a risk factor for liver cirrhosis: a systematic review and meta-analysis. (thieme-connect.com)
formerly known as primary biliary cirrhosis) is an autoimmune liver disorder characterized by the progressive destruction of intrahepatic bile ducts, leading. (msdmanuals.com)

Forty-seven adult recipients were classified as either left or right lobe grafted recipients. (elsevierpure.com)
In the right lobe donor group, the remnant liver volume was 45.4%, and it rapidly increased to 68.9% at 1 month and 89.8% at 6 months. (elsevierpure.com)
Livers of the right lobe donor group regenerated fastest in the donor groups, and the recipient liver regenerated faster than the donor liver. (elsevierpure.com)
The right lobe of the liver from the donor was then implanted uneventfully. (usuhs.edu)
In SLT, the liver is divided into a left lateral lobe (LLL) graft (segments 2 + 3) for a pediatric or small adult recipient and an extended right lobe (eRL) graft (segments 1 + 4-8) for an adult recipient. (medscape.com)
Gains in knowledge have led to the use of 2 hemiliver grafts-a left lobe (segment I-IV) and a right lobe (segment V-VIII)-for transplantation into 2 adults or adult-sized recipients. (medscape.com)

Donor kidneys could be from a deceased donor (DD) or a living donor (LD). (frontiersin.org)
Methods: Retrospective chart review of all patients who underwent living donor kidney transplant using kidneys procured laparoscopically at our centre was performed. (elsevierpure.com)
Conclusions: Recipient outcome is not compromised and excellent results can be achieved with living donor kidney transplantation using laparoscopically procured kidneys. (elsevierpure.com)
The next milestone in HIV-to-HIV transplantation is to demonstrate the safety of living donation now that we know deceased donor HIV-positive kidneys are safe for people living with HIV. (positivelyaware.com)
In the case of kidney transplantation, the use of organs from live donors produces better results medically than kidneys from deceased donors. (who.int)
Globally, just over half the kidneys transplanted each year are obtained from living donors, while in most developing countries almost all kidneys come from living donors. (who.int)
and so 2 kidneys and 2 corneas were transplanted to 4 recipients on May 27th and June 1st. (cdc.gov)
METHODS: In 2018, 2 kidneys and a liver were procured from a deceased donor resident of Kentucky, one of many states that was experiencing an HAV outbreak associated with person-to-person transmission through close contact, primarily among people who reported drug use. (cdc.gov)

Of 696 patients who underwent liver transplantation, the EBV viral load of 127 patients suspected of EBV infection/disease was examined intermittently in this retrospective study. (govaresh.org)

Over the following 30 years, the risk of death among patients on the pediatric wait list substantially declined because of the ability to use these reduced-size grafts and because of the subsequent introduction of live-donor transplantation. (medscape.com)
However, living-donor partial liver grafts are also used. (medscape.com)
In addition, research is needed to best understand liver function in small grafts and to ensure regeneration in the early period after transplantation. (medscape.com)
Although split-liver transplantation was initially used for deceased-donor grafts in the pediatric population, the lessons learned from split-liver transplantation have been successfully applied to live-donor liver transplantation to benefit both pediatric and adult recipients. (medscape.com)
At organ procuring, the liver and kidney grafts looked grossly normal. (cdc.gov)
However, such grafts place the recipients at greater risk for adverse events. (wjgnet.com)
Although some indispensable treatments are needed to address the deficiencies of these grafts, recipients can receive a favorable prognosis, similar to that of patients who receive standard liver grafts, under these treatments. (wjgnet.com)
BACKGROUND: Autologous portal vein Y-graft (PYG) interposition has been the standard procedure for reconstruction of double portal vein (PV) orifices of right liver grafts during living donor liver transplantations. (koreamed.org)
Grafts are prepared at the recipient transplant center and placed in an ice bath containing preservation solution. (medscape.com)

These include earlier exposure to the risks of immunosuppression and transplantation surgery ( 19 , 20 ), potential earlier loss of residual native kidney function and higher risk of non-adherence to immunosuppressants due to not having experienced the morbidity of dialysis ( 12 ). (frontiersin.org)

Background - Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD) is a quality improvement intervention designed to enhance access to kidney transplantation and living kidney donation. (ices.on.ca)
Living liver donation is a possible alternative, which could increase the amount of donor organs available in the short term. (bmj.com)
To assess the attitude towards living organ donation in the general population to have an overview of the overall attitude within Germany. (bmj.com)
Factors for and against living liver donation were assessed. (bmj.com)
Sex, religion, state of health and age of the donor, however, did not influence other questions on the readiness to consider living organ donation. (bmj.com)
The will for postmortem organ donation positively correlated with the will to be a living organ donor. (bmj.com)
Differences in donation readiness resulting from the situation of every donor and recipient are thoroughly outlined. (bmj.com)
The acceptance for a living liver donation was found to be high - and comparable to that of living kidney donation. (bmj.com)
Should gratitude be a requirement for access to live organ donation? (bmj.com)
Transplant Australia is a national charity representing transplant recipients, donor families, living donors and all those touched by organ and tissue donation and transplantation. (abnnewswire.net)
Our vision is for Australia to lead the world in organ and tissue donation and transplantation - saving lives, improving quality of life and providing much needed care and support. (abnnewswire.net)
They include those awaiting transplantation, donor families, living donors, transplant recipients, and the doctors, nurses and coordinators working in the organ and tissue donation and transplantation sector. (abnnewswire.net)
Contributed by leading international experts, the special issue papers highlight ongoing efforts to improve the selection and evaluation of living donors, their surgical and medical care during donation, and follow-up after the procedure. (sciencedaily.com)
Lifelong follow-up is essential for gaining a more complete understanding of the true risks of living donation. (sciencedaily.com)
Living-organ donation confronts patients, healthcare professionals, and society with a challenging set of concerns unlike any other type of procedure. (sciencedaily.com)
Another paper provides a thoughtful update on Iran's controversial paid living organ donation program. (sciencedaily.com)
RTI Donor Services is a not-for-profit organization that partners with tissue recovery organizations in acquiring donated tissue on behalf of RTI Surgical, with the goal of maximizing the gift of tissue donation to benefit recipients in need. (rtix.com)
Our focus is on delivering a high level of service to our recovery partners and developing safe, innovative regenerative health solutions that improve lives and maximize the gift of tissue donation. (rtix.com)
RTI Donor Services participates in the Pathways Thank You Letter Program as a way for transplant recipients to thank their donor families and express the impact their donation gift has had on their life. (rtix.com)
The generous gift of tissue donation can dramatically improve the quality of life for recipients. (rtix.com)
See how tissue donation and transplantation have touched the lives of others. (rtix.com)
Knowing the importance of living donation, I was hooked on the idea that I could become a living kidney donor. (positivelyaware.com)
An HIV-positive donor, who made her end-of-life donation decision known to her family, saved two lives that day. (positivelyaware.com)
While more organ donations are possible because of the HOPE Act, at least eight states have antiquated laws that prohibit people living with HIV from both deceased and living donation. (positivelyaware.com)
It's time to end such laws and remove related barriers to organ donation, so that people living with HIV can give the 'gift of life. (positivelyaware.com)
Advantages of living donation for the recipient include shorter waiting times and shorter cold ischemic times for explanted organs, largely because transplantation can be scheduled to optimize the patient's condition. (msdmanuals.com)
Organ and tissue donation and transplantation is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ or tissue. (who.int)
3 Global Observatory on Donation and Transplantation 2016. (who.int)
5 United Nations General Assembly - Resolution A/RES/71/322 on Strengthening and promoting effective measures and international cooperation on organ donation and transplantation to prevent and combat trafficking in persons for the purpose of organ removal and trafficking in human organs, September 2017. (who.int)
However, Kenya has already drafted new legislation which covers the donation of organs and tissues from both living and deceased donors, and eight Member States8 intend to adopt new legal requirements. (who.int)

This very special issue of Transplantation is dedicated to the approximately 33,000 living kidney and 5,000 living liver donors who provided organs for transplantation in 2014 across the world," comments Prof. Jeremy R. Chapman, Editor-in-Chief of Transplantation . (sciencedaily.com)
Scarcity of organs for transplantation makes living related donor transplantation lifesaving, but it may not be equitably distributed. (bmj.com)

We aimed to construct a simple clinical model to predict the effectiveness of TAC in recipients after pediatric LT and help clinicians to choose CsA for an alternative quickly. (authorea.com)
In addition to testing for HBV DNA at 4-6 weeks after transplantation, clinicians caring for liver transplant recipients should consider testing for HBV DNA 1 year after transplantation or at any time if signs and symptoms of viral hepatitis develop, even if previous tests were negative (2). (cdc.gov)

Common signs and symptoms may stem from decreased hepatic synthetic function (eg, coagulopathy), portal hypertension (eg, variceal bleeding), or decreased detoxification capabilities of the liver (eg, hepatic encephalopathy). (medscape.com)
In most cases, the left portal vein and the right hepatic artery are sectioned because they are long and thus facilitate anastomoses to the recipient vessels. (medscape.com)

The recipient was discharged on POD 6 and received an immunosuppression regimen of tacrolimus and mycophenolate. (cdc.gov)
A study that showed a greater incidence of adnexal skin tumours in organ transplant recipients than in immunocompetent individuals (7) corroborates the role of immunosuppression in syringoma development. (medicaljournals.se)
[ 1 ] Recipients were treated with intensive conventional immunosuppression , including combinations of prednisone , azathioprine , and antilymphocyte globulin. (medscape.com)

The virus must be undetectable, and the recipient must meet criteria for heart transplantation as well. (medscape.com)
Heart transplantation remains the gold standard for end-stage heart failure treatment. (medscape.com)

infections were detected a median of 38 from the same donor as the liver recipient were evaluated for (range = 5-116) weeks after transplantation. (cdc.gov)
A blood specimen collected 10 weeks after transplantation was positive for HIV antibody by EIA, and a specimen collected 1 week later was positive by both EIA and Western blot assay. (cdc.gov)
infections were detected a median of 38 (range = 5-116) weeks after transplantation. (cdc.gov)

During 2014-2019, CDC investigated 30 suspected cases of unavailable for the majority of recipients. (cdc.gov)
3 Crabb DW, Im GY, Szabo G, Mellinger JL, Lucey MR. Diagnosis and treatment of alcohol-associated liver diseases: 2019 practice guidance from the American Association for the Study of Liver Diseases. (thieme-connect.com)
During 2014-2019, CDC received 20 reports of HBV infection among recipients of livers from donors who had no evidence of past or current HBV infection. (cdc.gov)

Other risk factors for graft failure among recipients were male sex, African American race, re-transplantation, presence of diabetes, mechanical ventilation at the time of LT, higher MELD score, presence of portal vein thrombosis, HCV positive status, and higher DRI. (touro.edu)

Clinical Transplantation , 17 (SUPPL. (elsevierpure.com)

The researchers, on behalf of the OPTN Pediatric Transplantation Committee, studied early effects of a policy implemented in March 2016 that changed medical urgency criteria for pediatric candidates (ages newborn to 17) awaiting a heart transplant. (unos.org)
A survey conducted from September 2016 to December 2018 showed that only a limited number of Member States in the African Region had some legal requirements in place covering OTDT from living donors. (who.int)

There is long-term evidence of success with HIV-positive liver and kidney donors, and there have been improvements in medications to suppress HIV. (medscape.com)
The special issue publishes the evidence base for the KDIGO guidelines ( http://kdigo.org/home/guidelines/livingdonor/ ) on evaluation and follow-up care of living kidney donors, currently under development. (sciencedaily.com)
Glomerular filtration rates decreased at 2 to 4 years of follow-up for the first 3 living kidney donors with HIV. (renalandurologynews.com)
In a prospective study, Christine M. Durand, MD, from the Johns Hopkins University School of Medicine in Baltimore, and colleagues reported on the first 3 cases of living kidney donors with HIV. (renalandurologynews.com)

Campos, A.C.L., Matias, J.E.F. and Coelho, J.C.U. (2002) Nutritional Aspects of Liver Transplantation. (scirp.org)
The implementation of the model for end-stage liver disease (MELD) in 2002 represented a fundamental shift in liver donor allocation to recipients with the highest acuity, raising concerns about posttransplant outcome and morbidity. (escholarship.org)
Cite this: Intestine Transplantation - Medscape - Jun 01, 2002. (medscape.com)

20 reports of HBV infection among recipients of livers from were defined as unexpected, new,¶ reproducible laboratory donors who had no evidence of past or current HBV infection. (cdc.gov)

Morbidity and mortality of iatrogenic hemothorax occurring in a cohort of liver transplantation recipients: a multicenter observational study. (physiciansweekly.com)

Tacrolimus is the backbone immunosuppressant after solid organ transplantation. (frontiersin.org)
Tacrolimus (Tac) is the most commonly used immunosuppressor after solid organ transplantation. (frontiersin.org)
Liver transplantation is the 2nd most common type of solid organ transplantation. (msdmanuals.com)
28,000 solid organ transplantations are performed annually. (cdc.gov)

A speciality of our clinic is allogeneic and autologous stem cell Transplantation. (uniklinikum-dresden.de)
Younger Matched Unrelated Donors Confer Decreased Relapse Compared to Older Sibling Donors in Older B-cell ALL Patients Undergoing Allogeneic Hematopoietic Cell Transplantation. (stembook.org)
The report of the Madrid meeting3 outlines the main concerns about allogeneic and xenogeneic transplantation identified during the consultation process and highlights points of consensus. (who.int)
The consultations highlighted, however, that allogeneic (human-to-human) transplantation poses major challenges and that xenotransplantation, which offers a potential alternative to allogeneic transplantation in certain conditions, requires particularly rigorous oversight and management in view of its specific potential risks and related problems. (who.int)

Because injection drug or HBV DNA) in an organ recipient without evidence for HBV infection (anti-HBc, HBsAg, or HBV DNA) preceding transplantation. (cdc.gov)
Myocarditis Among Vaccine Recipients: Update from Total anti-HBc indicates past or current infection with HBV. (cdc.gov)
State and local health departments infection with hepatitis B. No behavioral risk factors or shared information about recipient behavioral risk factors and health care-associated hepatitis B outbreaks were reported in outbreaks of health-care-associated HBV infection. (cdc.gov)
unexpected, donor-derived HBV infection among liver recipi- ents. (cdc.gov)
We concluded that monitoring of EBV load might detect EBV infection/disease in liver transplant suspected recipients even several weeks before the onset of any manifestation, especially in pediatric cases in whom PTLD incidence and its mortality are high. (govaresh.org)
Cryptococcosis infection after transplantation is easily overlooked or misdiagnosed. (cdc.gov)
We report a cluster of donor-derived cryptococcosis infection in liver and kidney transplant recipients from the same donor in China. (cdc.gov)
Another feature of recipient-acquired cryptococcosis is the late onset of infection, which usually is 15‒21 months posttransplant ( 7 ). (cdc.gov)
The recipient showed good liver function for 30 months without active infection ( Table ). (cdc.gov)
The recipient is married and denied risk factors for HIV infection. (cdc.gov)
New cases of vector-borne T cruzi infection usually occur in persons who live in primitive houses in areas where the sylvatic cycle is active. (medscape.com)
[ 9 ] The use of TAC as the primary immunosuppressant in small bowel transplantation as well as improved surgical techniques, the availability of an increased array of potent immunosuppressive medications, infection prophylaxis, and suitable patient selection have contributed to the reality of this procedure for a growing number of patients who are total parenteral nutrition (TPN)-dependent and have permanent intestinal failure. (medscape.com)
We report the results of an investigation to determine the source of transmission and describe the clinical course of HAV infection in the infected kidney recipients. (cdc.gov)
Unexpected donor-derived hepatitis B virus (HBV) infection is defined as a new HBV infection in a recipient of a transplanted organ from a donor who tested negative for total antihepatitis B core antibody (total anti-HBc), hepatitis B surface antigen (HBsAg), and HBV DNA* before organ procurement. (cdc.gov)

Morbidity and Mortality Weekly Report archived donor serum, plasma, or liver biopsy samples were of nonliver organs** from the 20 donors developed a new tested for HBV DNA. (cdc.gov)
Malnutrition is a known risk factor for postoperative morbidity and mortality in patients awaiting liver transplantation (LT). Malnutrition is a potentially reversible risk factor, though there are no clear guidelines on the best mechanism for an improvement. (bvsalud.org)

Kidney transplantation (KT) is the preferred kidney replacement therapy (KRT) for suitable patients with end-stage kidney disease (ESKD) ( 1 ). (frontiersin.org)
Median age was 59 y, 36% were female , and median Model for End-Stage Liver Disease score was 20. (bvsalud.org)
In older recipient group female sex and Asian race were higher, while model for end-stage liver disease (MELD) score and rates of preoperative mechanical ventilation were lower ( (touro.edu)
This is scarring of the liver, caused by injury or long-term disease. (medlineplus.gov)
Given the high wait-list mortality rate among pediatric patients with end-stage liver disease and improved understanding of segmental liver anatomy, various techniques were developed to provide reduced-size allografts with complete arterial, portal, biliary, and venous drainage. (medscape.com)
However, donor-derived transmission should be considered if disease is found within 1 month posttransplant or if multiple recipients from the same donor become ill ( 8 , 9 ). (cdc.gov)
The second recipient was a 65-year-old man who had end-stage renal disease and received a kidney transplant from the same donor. (cdc.gov)
The gravity index (PELD)-pediatric end-stage liver disease-showed a negative correlation with the Alberta Infant Motor Scale (r = 0.83, p = 0.01). (scirp.org)
Conclusion: Infants with liver disease, even after transplantation, have delay in motor development, as well as changes in their nutritional and autonomic dysfunction. (scirp.org)
Zhao, V.M. and Ziegler, T.R. (2010) Nutrition Support in End-Stage Liver Disease. (scirp.org)
Carey, E.J., Gautam, M., Ingall, T. and Douglas, D.D. (2008) The Effect of Liver Transplantation on Autonomic Dysfunction in Patients with End-Stage Liver Disease. (scirp.org)
Comorbidities such as obesity and NASH have been shown to augment the deleterious effects of AUD and ALD, resulting in more advanced liver disease. (thieme-connect.com)
Measuring the alcohol in alcohol-associated liver disease: choices and challenges for clinical research. (thieme-connect.com)
The validity of viral hepatitis and chronic liver disease diagnoses in Veterans Affairs administrative databases. (thieme-connect.com)
Alcoholic liver disease epidemiology in the United States: a retrospective analysis of 3 US databases. (thieme-connect.com)
10 Bertha M, Shedden K, Mellinger J. Trends in the inpatient burden of alcohol-related liver disease among women hospitalized in the United States. (thieme-connect.com)
As people are living longer with HIV thanks to highly active antiretroviral therapy, they are also experiencing more kidney failure related to hypertension, diabetes, and cardiovascular disease-all of which can come with older age. (positivelyaware.com)
Transplanting their own (autologous) bone marrow-derived stem cells into 48 patients with end-stage liver disease resulted in therapeutic benefit to a high number of the patients, report researchers publishing in the current issue of Cell Transplantation (19:11). (medicaldaily.com)
Richard Franka] It's true that donor-derived disease transmission following organ transplantation has been reported for many different pathogens, essentially since the beginning of wider use of organ and tissue transplantation. (cdc.gov)
However, it is also true that only a fraction of 1 percent of all transplant procedures in the United States result in donor-derived disease in the recipient. (cdc.gov)
Any liver disease that affects the synthesis of clotting factors may manifest itself by an increase of prothrombin time (PT), which reflects the extrinsic pathway for the coagulation mechanism. (bvsalud.org)

Orthotopic liver transplantation (OLT) is usually associated with significant blood loss and frequently requires the usage of blood products. (usuhs.edu)
To analyze a 28-year single-center experience with orthotopic liver transplantation (OLT) for patients with irreversible liver failure. (escholarship.org)

Although not yet scientifically proven, evaluation and dental treatment during the pre-transplantation period is recommended in order to prevent infections and resultant odontogenic-origin sepsis during the post-transplant period, when patients receive immunosuppressive therapy. (bvsalud.org)

Conclusions: A simple clinical model with well performance in predicting the risk of poor curative effects of those recipients who receive an IS protocol based on TAC was constructed. (authorea.com)
CONCLUSIONS: Adherence to current guidance for hepatitis A vaccination may prevent future morbidity due to HAV among organ recipients. (cdc.gov)

Background: Tacrolimus (TAC) is the first choice of calcineurin inhibitors (CNIs) for recipients after pediatric LT. But there are some special pediatric recipients present an unsatisfied prognosis with the therapy of TAC. (authorea.com)

Infections occurred within 1 month after transplantation, and were confirmed by using biopsies and blood tests. (cdc.gov)
Both kidney recipients, residents of Virginia, subsequently developed acute HAV infections. (cdc.gov)
The donor and both kidney recipients were found to have a genetically identical strain of HAV using a next-generation sequencing-based cyber molecular assay (Global Hepatitis Outbreak Surveillance Technology), confirming donor-derived HAV infections in kidney recipients. (cdc.gov)

Anatomy22

Organisms7

Diseases78

Chemicals and Drugs29

Analytical, Diagnostic and Therapeutic Techniques and Equipment96

Phenomena and Processes15

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena2

Information Science4

Named Groups2

Health Care33

Geographicals1

Outcomes19

20222

Transplants13

Centers4

Donors and recipients4

Hepatocellular carcinoma3

20231

Complications20

Abstract2

LDLT6

Survival10

Cirrhosis7

Right lobe6

Kidneys8

Underwent liver transplantation1

Grafts9

Surgery1

Donation30

Organs for transplantation2

Clinicians2

Hepatic2

Immunosuppression3

Heart transplantation2

Weeks after transplantation3

20193

Risk factors for graft failure1

Clinical Transplantation1

20162

Kidney donors4

20023

Among recipients1

Observational study1

Solid organ4

Allogeneic4

Infection14

Morbidity and morta2

Disease21

Orthotopic2

Post-transplant1

Conclusions2

Tacrolimus1

Infections3