Proto-Oncogene Proteins c-bcl-2bcl-2-Associated X ProteinApoptosisReactive Oxygen SpeciesOxygenApoptosis Regulatory ProteinsOxygen ConsumptionOxidative StressCaspasesIron Regulatory Protein 1Caspase 3Hydrogen PeroxideMitochondriaMolecular Sequence DataSignal TransductionIron Regulatory Protein 2ColforsinCoat Protein Complex ICell LineAntioxidantsProtein BindingCell SurvivalInhibitor of Apoptosis ProteinsDNA FragmentationEnzyme ActivationAmino Acid SequenceNADPH OxidaseBase SequenceBlotting, WesternIn Situ Nick-End LabelingTranscription FactorsOxidation-ReductionDNA-Binding ProteinsRNA, MessengerLeucine-Responsive Regulatory ProteinBinding SitesTumor Cells, CulturedFree Radical ScavengersSuperoxide DismutaseX-Linked Inhibitor of Apoptosis ProteinMembrane Potential, MitochondrialMutationApoptosis Inducing FactorAcetylcysteinePhosphorylationTumor Suppressor Protein p53Gene Expression RegulationTransfectionCytochromes cEnzyme InhibitorsSinglet OxygenCaspase 9Cell ProliferationDose-Response Relationship, DrugCatalaseTime FactorsCaspase InhibitorsCell DeathSuperoxidesCarrier ProteinsIron-Regulatory ProteinsOxidantsBacterial ProteinsCell CycleCASP8 and FADD-Like Apoptosis Regulating ProteinModels, BiologicalFlow CytometryCaspase 8Oxygen Inhalation TherapyKineticsMice, Inbred C57BLRNA, Small InterferingPromoter Regions, GeneticGlutathioneProto-Oncogene Proteinsbcl-X ProteinFas Ligand ProteinDNA DamageTranscription, GeneticMembrane ProteinsDown-RegulationReactive Nitrogen SpeciesHeLa CellsGene Expression Regulation, BacterialRecombinant ProteinsRats, Sprague-DawleyAntineoplastic AgentsReverse Transcriptase Polymerase Chain ReactionMice, KnockoutProtein Structure, TertiaryNF-kappa BUp-RegulationMembrane GlycoproteinsAnnexin A5Cell DivisionPoly(ADP-ribose) PolymerasesRecombinant Fusion ProteinsCysteine Proteinase InhibitorsGene ExpressionRepressor Proteins