AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsInformation ScienceNamed GroupsHealth CareGeographicals
TelomeraseTelomereTelomere HomeostasisDyskeratosis CongenitaTetrahymena thermophilaRNACycloparaffinsHoloenzymesTelomere-Binding ProteinsDNA-Binding ProteinsPlatypusMutationChromosomes, Human, Pair 5Dermatologic Surgical ProceduresAlcoholicsTelomere ShorteningAging, PrematurePromoter Regions, GeneticCatalytic DomainOryziasIdiopathic Pulmonary FibrosisLiposarcoma, MyxoidTetrahymenaOctamer Transcription FactorsCardiomyopathy, AlcoholicReptilesCell AgingRNA, ProtozoanGenetic Predisposition to DiseaseProto-Oncogene Proteins c-mycMarsupialiaPolymorphism, Single NucleotideBone Marrow DiseasesMolecular Sequence DataSharksBase SequenceCase-Control StudiesRNA, MessengerAnemia, AplasticCell ProliferationGene Expression Regulation, EnzymologicCells, CulturedGenotypeTranscription, GeneticCell Line, TumorProtein Structure, TertiaryGenetic Association StudiesKetonesHair ColorRibonucleoproteinsProtein BindingDNA PrimersReverse Transcriptase Polymerase Chain ReactionKeratinocytesNeoplasmsMetaplasiaGlucuronatesCell LineSequence AlignmentHeterozygoteProto-Oncogene Proteins c-etsChromosomal InstabilityHair FollicleUp-RegulationRNA InterferenceApoptosisGenome-Wide Association StudyNucleic Acid ConformationFibroblastsBinding SitesSequence Homology, Amino AcidIn Situ Hybridization, FluorescenceAmino Acid SequenceNuclear ProteinsTumor Suppressor Protein p53MCF-7 CellsApoptosis Inducing FactorUpstream Stimulatory FactorsImmunohistochemistryEmbryonic Stem CellsHeLa CellsGene Expression Regulation, NeoplasticErythrocyte CountAlternative SplicingCell Line, TransformedDNA Mutational AnalysisAmino Acid MotifsMice, TransgenicImmunoprecipitationNeoplasm ProteinsReal-Time Polymerase Chain ReactionHair14-3-3 ProteinsSex ChromosomesPulmonary FibrosisSyntenyLinkage DisequilibriumGliomaCell Transformation, NeoplasticGene Expression Regulation
OxidantTBHPLipid peroxidationCatalystAcetic acidIonic liquidsEpoxidation reactionInduceOxidationSynthesisCyclization reactionsFunctionalization reactionsYieldOxygenMechanismCatalyticOxidationsCompoundsAlcoholsChemistryCatalystsRegioselectiveTemperatureAlkynesQuantitativeEnzymesLigandAmidesPolymersConditionsOxidizing agentAdditionConcentrationHumanStudyWaterTime
Oxidant7
  • In addition to TBAI, tert -butyl hydroperoxide (TBHP) is used as an oxidant. (chemistryviews.org)
  • The use of tert -butyl hydroperoxide as an oxidant and an inexpensive and air stable copper catalyst enables a simple and efficient protocol for the oxidative amidation of commercially affordable alcohols to Weinreb amides in very good yields. (organic-chemistry.org)
  • of tert-butyl hydroperoxide as oxidant at 25 °C. In order to design the subsequent separation step using CO2 extraction, it is critical to have the knowledge on the phase behavior of the systems involved. (tudelft.nl)
  • Reaction of the carbonyl complexes with the oxidant tert -butyl hydroperoxide (TBHP) (either separately or in situ) gives oxomolybdenum(VI) hybrid materials that are proposed to possess one-dimensional polymeric structures in which adjacent oxo-bridged dioxomolybdenum(VI) moieties are further linked by bidentate bridging triazole (trz) ligands. (nih.gov)
  • The catalytic performance of these catalysts was investigated in the selective oxidation of ethylbenzene with tert -butyl hydroperoxide as oxidant. (chempap.org)
  • There has been considerable effort to develop alternative alkene epoxidation methods by employing an oxidant such as tert-butyl hydroperoxide (TBHP) as it is environmentally benign, safer to handle and possesses good solubility in polar solvents. (lancs.ac.uk)
  • Furthermore, the efficiency of the heterogeneous catalyst for continuous epoxidation studies have been assessed using a FlowSyn continuous flow reactor by studying the effect of reaction temperature, feed molar ratio of alkene to TBHP and feed flow rate on the conversion of the oxidant and the yield of corresponding epoxide. (lancs.ac.uk)
TBHP6
  • The mechanism proposed for the reaction includes the in situ generation of hypoiodite from TBAI and TBHP, which reacts with the carbonyl compound. (chemistryviews.org)
  • Mittels mechanistischer Untersuchungen konnte gezeigt werden, dass Vanadium-Schiffbasekomplexe mit tert-Butylhydroperoxid (TBHP) zu Peroxykomplexen (ESI-MS, 51V-NMR) reagieren. (uni-wuerzburg.de)
  • Results from mechanistic studies have indicated that (schiffbase)vanadium(V) complexes react with tert-butyl hydroperoxide (TBHP) to furnish peroxy complexes (ESI-MS, 51V NMR). (uni-wuerzburg.de)
  • Experiments have been carried out to study the effect of reaction temperature, feed molar ratio of alkene to TBHP and catalyst loading on the yield of 1,2-epoxyhexane and 4-vinyl-1-cyclohexane 1,2-epoxide (4-VCH 1,2-epoxide) to optimise the reaction conditions in a batch reactor. (lancs.ac.uk)
  • Within Ti-BEA, the rates of 1-octene epoxidation with H2O2 are 30 and 170 times greater than reactions with TBHP or CHP, respectively. (illinois.edu)
  • In contrast, 1-octene epoxidation rates in Ti-SBA-15 with H2O2 are 7- A nd 40-fold higher than in reactions with TBHP or CHP, respectively. (illinois.edu)
Lipid peroxidation2
  • In vitro exposure of erythrocytes to oxygen radical generating systems (such as H 2 O 2 , ascorbate/Fe 3+ , cumene hydroperoxide, tert-butyl hydroperoxide, etc.) was shown to induce lipid peroxidation, protein degradation, loss of deformability, an increase in osmotic fragility, membrane lipid bilayer perturbation, inhibition of enzymes and hemolysis [5-12]. (scirp.org)
  • With the exception of 1-pentyl- and 1-(2'-oxopropyl)-3,7-dimethyluric acids, all other analogues tested are effective inhibitors of tert-butylhydroperoxide-induced lipid peroxidation in human erythrocyte membranes. (iisc.ac.in)
Catalyst10
  • The catalytic epoxidation reaction of cinnamyl alcohol in the presence of ionic liquids was optimized with respect to various parameters: (i) type and amount of oxidizing agent, (ii) type and amount of catalyst, (iii) type of ionic liquids (ranging from hydrophobic to hydrophilic), and (iv) temperature. (tudelft.nl)
  • Aftercompletion of the reaction, 10 cm3acetonitrile was addedto the reaction mixture and the mixture heated for 10 minat 50 °C. After that, the catalyst was separated from thereaction mixture by filtration and the organic residue wasextracted with 20 cm3EtOAc, washed with 10 cm3distilledwater, dried over MgSO4,and recrystallized in a mixture ofEtOH and H2Oto obtain the pure product. (ambeed.com)
  • More precisely the invention concerns a method for oxidizing hydrocarbon, alcohol and/or ketone using oxygen or an oxygen-containing gas, in liquid phase and in the presence of a catalyst dissolved in a reaction medium. (allindianpatents.com)
  • Another common catalyst for this oxidation reaction which may be mentioned is manganese. (allindianpatents.com)
  • More specifically, the invention consists of a process for oxidizing hydrocarbon, alcohol and/or ketone using oxygen or a gas containing it, in a liquid phase and in the presence of a catalyst dissolved in the reaction medium, characterized in that the catalyst comprises at least one soluble manganese and/or cobalt compound, at least one soluble chromium compound and at least one soluble iron compound. (allindianpatents.com)
  • However, homogenous catalysed alkene epoxidation has several drawbacks including deposition of catalyst on the reactor walls and increased difficulties in separation of catalyst from the reaction mixture. (lancs.ac.uk)
  • A detailed evaluation of molybdenum (Mo) leaching from the polymer supported catalyst has been investigated by isolating any residue from reaction supernatant solutions and then using these residues as potential catalyst in epoxidation reactions. (lancs.ac.uk)
  • The continuous flow epoxidation using FlowSyn reactor has shown considerable time savings, high reproducibility and selectivity along with remarkable improvements in catalyst stability compared to reactions carried out in a batch reactor. (lancs.ac.uk)
  • When used as catalyst precursors for the epoxidation of cis-cyclooctene by tert-butylhydroperoxide at 55 degrees C (1 mol% catalyst (Mo), no additional co-solvent), 1,2-epoxy-cyclooctane was obtained as the only reaction product in quantitative yield after 5 h for 1 and 36% yield after 24 h for the supported complex. (ua.pt)
  • The catalyst was magnetically recovered and reused in the addition reaction five times without a significant reduction in catalytic activity and yield. (nsmsi.ir)
Acetic acid1
  • Further potential but not confirmed hydrolysis products are acetic acid and tert-butyl hydroperoxide. (europa.eu)
Ionic liquids3
  • As a result of these properties, there are many reports where ionic liquids have been used as solvents for chemical reactions. (tudelft.nl)
  • First, the epoxidation reaction of cinnamyl alcohol to 3-phenylglycidol was studied in the presence of ionic liquids as solvents. (tudelft.nl)
  • Therefore, the high-pressure phase behavior of ternary systems containing epoxidation reaction compounds, ionic liquids and scCO2 were measured. (tudelft.nl)
Epoxidation reaction2
  • The Sharpless epoxidation reaction is an enantioselective chemical reaction to prepare 2,3-epoxyalcohols from primary and secondary allylic alcohols. (wikipedia.org)
  • Finally, using data obtained during this work, the conditions for carrying out the epoxidation reaction in a homogeneous phase and extracting the product with scCO2 in the two-phase region are determined. (tudelft.nl)
Induce1
  • To measure ROS levels, nematodes were treated with a tert-butylhydroperoxide insult to induce ROS generation, along with H2DCFDA dye to fluoresce when oxidized by ROS, pipetted into a 96-well plate, and ran through a microplate reader. (etsu.edu)
Oxidation3
  • Since Haruta's discovery of the catalytic activity of gold nanoparticles (GNPs), GNPs have been of great interest in chemistry, dispersed on metal oxides and in CO oxidation reaction [1] . (beilstein-journals.org)
  • The impacts of temperature, mass of catalysts, reaction time and oxidants on the selective oxidation of ethylbenzene were also investigated. (chempap.org)
  • 9] MAHDAVI V, MARDANI M. Selective oxidation of benzyl alcohol with tert-butylhydroperoxide catalysed via Mn (II) 2, 2-bipyridine complexes immobilized over the mesoporous hexagonal molecular sieves (HMS)[J]. J Chem Sci, 2012, 124(5): 1107-1115. (jccsoc.com)
Synthesis5
  • The mild and "green" reaction proceeds in water, and allows the synthesis of a variety of azide-functionalized β-keto esters, amides, and ketones in good yields. (chemistryviews.org)
  • This review presents the recent progress of oxygen functionalization reactions based on non-electrochemical (conventional organic synthesis) and electrochemical methods. (rsc.org)
  • His research focuses on the fundamental understanding of electrochemical reactions and organic electrosynthesis including various oxygen-atom functionalization catalysis, asymmetric synthesis, biochemical reactions. (rsc.org)
  • Cichowicz NR, Kaplan W, Khomutnyk Y, Bhattarai B, Sun Z, Nagorny P (2015) Concise enantioselective synthesis of oxygenated steroids via sequential copper(II)-catalyzed michael addition/intramolecular aldol cyclization reactions. (springer.com)
  • Synthesis of a trans,syn,trans-dodecahydrophenanthrene via a bicyclic transannular Diels-Alder reaction: intermediate for the synthesis of fusidic acid. (tamu.edu)
Cyclization reactions1
  • These substrates can undergo cyclization reactions upon treatment with electrophilic brominating reagents. (uni-wuerzburg.de)
Functionalization reactions3
  • We hope to direct the attention of readers to the latest breakthroughs of traditional oxygen functionalization reactions and to the potential of electrochemistry for the transformation of organic substrates to useful end products. (rsc.org)
  • During his postdoctoral research at the Massachusetts Institute of Technology (MIT), he studied the electrochemical oxygen functionalization reactions. (rsc.org)
  • Based on the structure of the molecule, the test item may be metabolized by Phase I enzymes undergoing functionalization reactions aiming to increase hydrophilicity. (europa.eu)
Yield1
  • While the yield of a kinetic resolution process cannot be higher than 50%, the enantiomeric excess approaches 100% in some reactions. (wikipedia.org)
Oxygen1
  • Whole body knockdown of nadk-1 to decrease cytoplasmic NADPH levels decreased oxygen consumption and tert-butyl hydroperoxide-stimulated ROS levels, which was phenocopied by intestine-specific or neuron-specific knockdown. (etsu.edu)
Mechanism2
  • Mechanism of the acid-promoted intramolecular schmidt reaction: theoretical assessment of the importance of lone pair-cation, cation-, and steric effects in controlling regioselectivity. (tamu.edu)
  • Isotope effects and the mechanism of epoxidation of cyclohexenone with tert-butyl hydroperoxide. (tamu.edu)
Catalytic2
  • Nevertheless, it turns out that although the selectivities obtained with the catalytic systems used in the prior-art processes described above are acceptable, the production efficiency of these processes needs to be further improved in order to allow such a reaction to be exploited industrially. (allindianpatents.com)
  • A pronounced ligand influence on catalytic performance was only found for the hybrids [MoO₃(trz) 0.5 ], and only the 1,2,4-trz compound displayed reaction-induced self-precipitation behavior. (nih.gov)
Oxidations1
  • The reactants for the Sharpless epoxidation are commercially available and relatively inexpensive.K. Barry Sharpless published a paper on the reaction in 1980 and was awarded the 2001 Nobel Prize in Chemistry for this and related work on asymmetric oxidations. (wikipedia.org)
Compounds3
  • Traditional chemical processes show shortcomings caused by using volatile organic compounds as solvents during reactions and separations. (tudelft.nl)
  • Lewis Acid-Activated Reactions of Silyl Ketenes for the Preparation of -Silyl Carbonyl Compounds. (tamu.edu)
  • The reactions between α-dicarbonyl compounds (MGO, GO, and 3-DG) and GSH were studied by LC-MS in a cell-free system. (ebsco.com)
Alcohols1
  • en)Disclosed are novel (meth)acrylic esters of unsaturated amino alcohols, a process for their preparation and their use for preparing crosslinked swellable hydrogel-forming polymers and crosslinked swellable hydrogel-forming polymers. (vtex.vn)
Chemistry3
  • The Biginelli reaction, one of the oldest and most famous MCRs, has sparked new scientific discoveries in polymer chemistry since 2013. (mdpi.com)
  • The demand for green and sustainable chemistry has fostered for the development of new reactions and chemical processes in steroidal chemistry. (springer.com)
  • Recent Progress in the Reactions of Aurone-Derived Azadienes [J]. Chinese Journal of Organic Chemistry, 2020, 40(9): 2714-2724. (sioc-journal.cn)
Catalysts3
  • The reaction occurs at a convenient rate only in the presence of certain finely divided metal catalysts , such as nickel (Ni), platinum (Pt), palladium (Pd), or rhodium (Rh). (britannica.com)
  • 8] CLIMENT M J, CORMA A, IBORRA S. Homogeneous and heterogeneous catalysts for multicomponent reactions[J]. RSC Adv, 2012, 2(1): 16-58. (jccsoc.com)
  • SN2 Reactions in Hydrocarbon Solvents Using Ammonium-Terminated Polyisobutylene Oligomers as Phase-Solubilizing Agents and Catalysts. (tamu.edu)
Regioselective2
  • The term regioselective describes the preference for a reaction that occurs in one direction rather than another, as in the addition of sulfuric acid to propylene. (britannica.com)
  • A regiospecific reaction is one that is 100 percent regioselective. (britannica.com)
Temperature1
  • A new process set-up based on this phase behavior has been proposed, in which the reaction is carried out in a homogenous phase at high rate (no mass transfer limitations) by selection of a suitable pressure, temperature and CO2 concentration. (tudelft.nl)
Alkynes1
  • Mechanistic Studies of Formal Thioboration Reactions of Alkynes. (tamu.edu)
Quantitative1
Enzymes1
  • The first hydrolysis product tert-butyl alcohol has a low molecular weight of 74.12 g/mol, is miscible in water and thus may either be directly excreted or further metabolised by Phase II enzymes before excretion. (europa.eu)
Ligand1
  • The ligand N-(n-propyl)-2-pyridylmethanimine (pyim) and an immobilised analogue of this ligand (MCM-41-pyim) were prepared by the condensation reaction of 2-pyridinecarboxaldehyde with either propylamine or aminopropyl groups covalently attached to the ordered mesoporous silica MCM-41. (ua.pt)
Amides1
  • A Metal-Free Three-Component Reaction of trans--Nitrostyrene Derivatives, Dibromo Amides, and Amines Leading to Functionalized Amidines. (tamu.edu)
Polymers2
  • Multicomponent reactions (MCRs) have been used to prepare polymers with appealing functions. (mdpi.com)
  • In this mini-review, we mainly summarize the recent progress of using the Biginelli reaction to identify polymers for biomedical applications. (mdpi.com)
Conditions2
  • After completion of the reaction, a phase separation is induced by changing the conditions. (tudelft.nl)
  • Optimization of the conditions revealed that product stability is the key factor in determining the reaction conditions. (tudelft.nl)
Oxidizing agent1
Addition1
  • The most important application of this reaction is the addition of chlorine to ethylene to give 1,2-dichloroethane, from which vinyl chloride is prepared. (britannica.com)
Concentration1
  • Seminal MDA concentration was measured by thiobarbituric acid reaction method. (ijbs.com)
Human1
  • However, Free radical reactions occur in the human body and food systems. (scirp.org)
Study1
  • In order to scale up the reaction in an ionic liquid/scCO2 miscibility switch system, a study was started to select the optimum ionic liquid in this case. (tudelft.nl)
Water1
  • One source of industrial ethanol, for example, is the reaction of ethylene with water in the presence of phosphoric acid . (britannica.com)
Time1
  • As one of the few highly enantioselective reactions during its time, many manipulations of the 2,3-epoxyalcohols have been developed. (wikipedia.org)