Radiotherapy induced neoplasms radiation induced. Medical search. Frequent questions

Further studies that account for chemotherapy and examine frequency and duration of radiotherapy would be of interest in confirming the observed association. (nih.gov)
Radiation therapy is synergistic with chemotherapy, and has been used before, during, and after chemotherapy in susceptible cancers. (wikipedia.org)
It is also common to combine radiation therapy with surgery, chemotherapy, hormone therapy, immunotherapy or some mixture of the four. (wikipedia.org)
Evidence on the impact of chemotherapy on radiotherapy-induced second malignant neoplasms is controversial. (bvsalud.org)
What Is the Cardiac Impact of Chemotherapy and Subsequent Radiotherapy in Lymphoma Patients? (cnr.it)
These disturbances in the integrity and function of the buccal cavity are due to the fact that radiotherapy and chemotherapy are incapable of destroying tumoral cells without injuring normal cells. (bvsalud.org)
In general, salivary gland neoplasms respond poorly to chemotherapy, and adjuvant chemotherapy is currently indicated only for palliation. (medscape.com)
There are many treatment options for HC caused by radiation or chemotherapy. (healthybladderclub.com)
It may be seen in greater than 90% of patients older than 60 years who have been successfully treated with combination chemotherapy and whole-brain radiation. (medscape.com)
Advanced head and neck squamous cell carcinoma (HNSCC) is treated with radiotherapy, chemotherapy, targeted therapy or a combination of these treatments. (researchsquare.com)
Findings were categorized by type of treatment (radiotherapy, chemotherapy, targeted therapy, or combination therapy). (researchsquare.com)
Treatment of HNSCCs includes one of the surgery, radiotherapy or chemotherapy treatments or a combination of these treatments. (researchsquare.com)
Some cases have been associated with resistance to radiotherapy or chemotherapy and local recurrence. (researchsquare.com)
The goal of these response through neoadjuvant chemotherapy, policies is to establish collective guidelines to particularly usinga nthracyclines and taxanes-based increase health and quality of life through combination, surgery, radiotherapy and hormone- prevention, treatment of disease and health based therapy5. (bvsalud.org)
Furthermore, it helps with reducing complications due to cancer or its treatments such as postoperative ileus and severity of peripheral neuropathy induced by chemotherapy, and improves cancer-related fatigue, lymphopenia, and quality of life. (researchgate.net)
In these individuals, there may exist chemotherapy-induced neutropenia and/or mucositis and radiation-induced tissue injury, which facilitate fungemia by Candida spp. (biomedcentral.com)
Data about sociodemographic characteristics, the type of neoplasm and the chemotherapy scheme proposed were collected. (bvsalud.org)

An angiosarcoma (AS) is an uncommon malignant neoplasm characterized by rapidly proliferating, extensively infiltrating anaplastic cells derived from blood vessels and lining irregular blood-filled spaces. (medscape.com)
Furthermore, the potential risk of second malignant neoplasm induction is also posing a radiation protection dilemma in case of proton therapy. (su.se)
Esophageal cancer is the common malignant neoplasm, which arises from the mucosa or gland of the esophagus. (biomedcentral.com)

Radiation-induced angiosarcomas occur in the absence of chronic lymphedema after radiotherapy for carcinoma of the cervix , ovary , endometrium , or breast and Hodgkin lymphoma . (medscape.com)
The first evidence that radiotherapy enhances the efficacy of immune checkpoint blockers (ICB) was obtained a dozen years ago in a mouse model of metastatic carcinoma refractory to anti-CTLA-4 treatment. (aacrjournals.org)
Hepatoblastomas with carcinoma features represent a biological spectrum of aggressive neoplasms in children and young adults. (ucsf.edu)

Read how proton therapy can reduce this risk and other effects of radiotherapy. (appliedradiationoncology.com)
A new form of 5-fluorouracil called fluoropyrimidine that has increased activity against malignant cells and while having fewer gastrointestinal side effects has shown to be efficacious against malignant salivary cancers and to potentiate the effects of radiotherapy by increasing apoptosis. (medscape.com)

The overall incidence of PRS is lower than 1% for patients with cancer who are treated with radiation and survive 5 years. (medscape.com)
Patients treated with radiation only (RR=1.64, 95%CI=1.18-2.29) or radiation with surgery (RR=1.49, 95%CI=1.07, 2.06) had elevated risks of developing a second primary tumor, whereas patients treated with surgery only did not appear to be at increased risk (RR=1.28, 95%CI=0.93, 1.76). (nih.gov)
Renal cell cancer and melanoma are generally considered to be radioresistant but radiation therapy is still a palliative option for many patients with metastatic melanoma. (wikipedia.org)
Conclusions: Small target movements can significantly reduce target proton radiotherapy dose during treatment of prostate cancer patients. (korea.ac.kr)
Using γ-H2AX and global genome expression analysis, we studied the biological responses induced by low doses of ionizing radiation in prostate cancer patients following IMRT. (itg.be)
In addition, Proton therapy for radiation-induced parameningeal rhabdomyosarcoma by Dr. Cooper and colleagues from Medical University of South Carolina, Charleston, outlines how patients with heritable retinoblastoma face a heightened risk of developing secondary malignant neoplasms-a risk that's significantly increased by radiotherapy. (appliedradiationoncology.com)
Between November 1999 and January 2002, eighty patients with head and neck cancers who were referred to the Radiotherapy Department of Nemazee Hospital were divided into two groups. (pdftreatment.com)
Clinical and histopathological evaluation of sucralfate in prevention of oral mucositis induced by radiation therapy in patients with head and neck malignancies. (pdftreatment.com)
One of these is radiation therapy (RT), which is used in 20-55% of cancer patients, and its basic principle consists of inhibiting proliferation or inducing apoptosis of cancer cells. (elsevierpure.com)
Radiation to the heart is a common complication of RT, especially in patients with lymphoma, breast, lung, and esophageal cancer. (elsevierpure.com)
The understanding of these mechanisms and risk factors by physicians can lead to a tailored assessment and monitorization of these patients with the objective of early detection or prevention of radiation-induced heart disease. (elsevierpure.com)
Radiotherapy (RT) is an effective treatment for palliative patients with painful bone metastases. (centerwatch.com)
Therefore, single fraction radiation therapy (SFRT) is encouraged, but 20 Gy in 5 fractions is also allowed in this study, though should be chosen only in patients with a complicated bone metastases by fracture, neurological deficit (e.g. spinal cord compression), or a large soft tissue component. (centerwatch.com)
Thereafter, some patients progressing on ipilimumab showed systemic responses only upon receiving radiation to one lesion, confirming clinically the proimmunogenic effects of radiation. (aacrjournals.org)
This study aimed to evaluate the impact of 1% Pilocarpine mouthwash on salivary flow in patients with radiation-induced xerostomia. (ac.ir)
This double-blind, randomized clinical trial involved 63 patients with radiation-induced xerostomia. (ac.ir)
Unstimulated saliva production in patients was measured using the spitting method at three stages: two weeks before the commencement of radiotherapy, two weeks after, and four weeks after the completion of radiotherapy. (ac.ir)
The impact of radiation treatment time on survival in patients with head and neck cancer. (ac.ir)
Hyperbaric oxygen therapy can relieve symptoms of late radiation cystitis in patients who underwent radiotherapy of the pelvic region for prostate cancer. (healthybladderclub.com)
Hyperbaric oxygen therapy can relieve symptoms of late radiation cystitis in patients who underwent radiotherapy of the pelvic region for prostate cancer or other malignancies, according to the results of a new randomized trial. (healthybladderclub.com)
Late radiation cystitis is reported in 5% to 15% of patients after radiotherapy for prostate, rectal, or gynecologic cancers. (healthybladderclub.com)
Previous work suggested that hyperbaric oxygen therapy, where patients breathe pure oxygen at an increased ambient pressure in a hyperbaric chamber, could relieve some symptoms of late radiation cystitis, but prospective, randomized data was lacking. (healthybladderclub.com)
With four locations in San Antonio, Dallas, Lewisville, and Arlington we are able to help patients suffering from unpleasant radiation symptoms and assist with the bodys overall healing. (healthybladderclub.com)
Racial differences in the risk of second primary bladder cancer following radiation therapy among localized prostate cancer patients. (musc.edu)
In addition, based on its expertise in radiation protection, radiation biology and cancer cytogenetics, HPRC offers specialized services for the calibration of radiation survey meters, for the development of individualized protocols for radiotherapy treatment and for the diagnostic cytogenetic evaluation of patients with hematological neoplasms. (demokritos.gr)
They note that although radiation therapy can provide some palliation in such patients, it can also result in radiation necrosis and neurologic decline. (medscape.com)
Therefore, knowing the genetic variations (polymorphisms) will be effective in predicting the response to treatment, and accordingly, we can determine which patients will benefit from chemo- or radiotherapy (Ansell et al. (researchsquare.com)
Feasibility of the Audio-Visual Assisted Therapeutic Ambience in Radiotherapy (AVATAR) System for Anesthesia Avoidance in Pediatric Patients: A Multicenter Trial. (uci.edu)
Methods and Materials: Patients with localized prostate cancer received amifostine as a rectal suspension 30-45 minutes before daily three-dimensional conformal radiation therapy. (johnshopkins.edu)
Seven weeks after the start of radiation therapy, the incidence of RTOG Grade 2 toxicity was 33% in the 1-g group (6/18 patients) compared with 0% (0/12 patients) in the 2-g group and trended toward statistical significance (p = 0.06). (johnshopkins.edu)
There is an urgent need for better triage of patients, especially in third world countries, in order to decrease the pressure induced on healthcare facilities. (bvsalud.org)
METHOD: Four different radiotherapy techniques, including 3D-conformal with anterior and posterior fields (3D-CRT AP-PA), 3D-conformal with 8 coplanar fields (3D-CRT 8 fields), eight fields intensity-modulated radiotherapy (IMRT), and volumetric modulated arc therapy using 2 full arcs (VMAT) were planned on the CT images of 32 COVID-19 patients with the prescribed dose of 1 Gy to the lungs. (bvsalud.org)
However, the overall estimated risks induced by IMRT and VMAT radiotherapy techniques were lower than the 3D-CRT techniques and can be used clinically in younger patients or patients having greater concerns about radiation induced cancers. (bvsalud.org)
Seven eyes of 7 patients diagnosed with symptomatic CCH who underwent ruthenium-106 plaque radiotherapy were included in the study. (cnr.it)
The present research project has a high relevance for the radioprotection of patients undergoing proton therapy as it aims at treatment planning optimisation having as objectives the minimisation of the normal tissue toxicity and the reduction of the risk of developing a second tumour induced by the initial treatment. (su.se)

Accelerated fractionation radiotherapy for laryngeal cancer: Acute and late toxicity. (pdftreatment.com)
VMAT (Volumetric Modulated Arc Therapy) is a type of 3D conformal RT, and delivers the radiation dose more conformally than SUPR, possibly reducing acute and late toxicity. (centerwatch.com)
Serotonin Toxicity and Urinary Analgesics: A Case Report and Systematic Literature Review of Methylene Blue-Induced Serotonin Syndrome. (musc.edu)
On the other hands, researches have been conducted to find molecular markers for predicting the development of treatment-induced acute or chronic toxicity before initiation of treatment (Venkatesh et al. (researchsquare.com)
Purpose: To test whether intrarectal amifostine limits symptoms of radiation proctitis, measured by using the Radiation Therapy Oncology Group (RTOG) gastrointestinal (GI) toxicity score and the Expanded Prostate Cancer Index Composite (EPIC) score. (johnshopkins.edu)
The current 1.1 RBE paradigm, however, has started to be questioned as clinical evidence is gathering pointing towards cases of radiation induced toxicity in the normal tissue that cannot be directly attributed to uncertainties in patient set-up or proton range. (su.se)
This project aims therefore at investigating and developing proton treatment planning optimisation approaches that would reduce both the deterministic toxicity and the stochastic effects for the same quality of the plan with respect to the target coverage minimising therefore the radiation protection concerns regarding proton therapy. (su.se)

This also may be an etiology for the changes seen with radiation necrosis. (medscape.com)

Attention should be given to interfractional target movement along the longitudinal direction, as image-guided radiotherapy may be ineffective if margins are not sufficient. (korea.ac.kr)

Urinary Bladder Neoplasms" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (musc.edu)
This graph shows the total number of publications written about "Urinary Bladder Neoplasms" by people in this website by year, and whether "Urinary Bladder Neoplasms" was a major or minor topic of these publications. (musc.edu)
Below are the most recent publications written about "Urinary Bladder Neoplasms" by people in Profiles. (musc.edu)

Intensity modulated radiotherapy (IMRT) is one of the modern conformal radiotherapies that is widely used within the context of cancer patient treatment. (itg.be)

Individualized Stereotactic Ablative Radiotherapy for Lung Tumors: The iSABR Phase 2 Nonrandomized Controlled Trial. (uci.edu)

The exposure of humans to ionizing radiation (IR) induces several types of genetic and somatic mutations leading to several types of cancers including breast cancer [ 1 ]. (biomedcentral.com)
Therefore, the types of ious forms of radiation, carcinogen ifested as a higher incidence of the tumours that occur during childhood ic infectious agents, and chemicals same kinds of tumours that occur in in humans, including various embry and chemical mixtures. (who.int)

Radiotherapy for oral cancer appears to be a risk factor for second primary tumors. (nih.gov)
Many recent studies have demonstrated that cellular senescence plays a crucial role in the regression of tumors exposed to ionizing radiation (IR), but the underlying mechanism remains unknown. (korea.ac.kr)
The use of radiation in T1 and T2 parotid gland tumors found that 5-year disease-free survival increased from 70% to 92% with postoperative radiation. (medscape.com)
Impacts of prior brain RT on recurrent tumors are poorly understood, though increasing evidence suggests RT-induced changes in the brain microenvironment contribute to recurrent GBM aggressiveness. (elsevierpure.com)
Preclinical data demonstrate that multiple immunomodulators synergize with radiotherapy to cause the regression of irradiated tumors and, less often, nonirradiated metastases. (aacrjournals.org)
Radiation necrosis can occur when radiotherapy is used to treat primary CNS tumors, metastatic disease, or head and neck malignancies. (medscape.com)

Doxorubicin- and platinum-based agents are most commonly used with the platinum-based agents that induce apoptosis versus the doxorubicin-based drugs that promote cell arrest. (medscape.com)
WISP2 overexpression inhibited cell growth and induced cell apoptosis, suppressed cell migration and invasion in ESCC cells. (biomedcentral.com)

It is estimated that half of the US' 1.2M invasive cancer cases diagnosed in 2022 received radiation therapy in their treatment program. (wikipedia.org)
TASTRO-TSOC Cardio-Oncology Task Force 2022, ' Risk Management for Radiation-Induced Cardiovascular Disease (RICVD): The 2022 Consensus Statement of the Taiwan Society for Therapeutic Radiology and Oncology (TASTRO) and Taiwan Society of Cardiology (TSOC) ', Acta Cardiologica Sinica , 卷 38, 編號 1. (tmu.edu.tw)

Radiation may be prescribed by a radiation oncologist with intent to cure or for adjuvant therapy. (wikipedia.org)
Contrary to this finding, other researchers suggest that adjuvant radiotherapy increases the risk of breast angiosarcoma 9-fold. (medscape.com)

But chemo-therapy and radiation therapy were not taken and the patient remained in a good condition throughout the 9-year follow-up period. (scirp.org)
To the best of our knowledge, our case is the sixth case that primary adenosarcomas arising in vaginal endometriosis and it is the first case living without chemo-therapy or radiotherapy. (scirp.org)
However, the current therapeutic options for cancer such as chemo-therapy, radiotherapy, and surgery may produce serious adverse events such as nausea, vomiting, fatigue, and peripheral neuropathy, especially in the long term. (researchgate.net)

This is a systematic review of studies in the PubMed database to April 2013, which fit the eligibility criterion of "Inflammatory Breast Neoplasms" (MeSH Terms), filtered by Languages (English OR Portuguese OR Spanish). (bvsalud.org)

In order to deliver 3D Conformal Radiotherapy, a computerized tomography (CT) simulation is used to develop the treatment plan. (centerwatch.com)

In early years, besides being employed in the treatment of a variety of malignancies, radiation was used to treat benign conditions, such as acne , fungal infections, eczema, and various bone diseases. (medscape.com)
Newer techniques for postoperative radiation in salivary gland malignancies have been proven effective. (medscape.com)
Efffects of sucralfate on mucositis during and following radiotherapy of malignancies in the head and neck region : A double blind placebo controlled study. (pdftreatment.com)

16]Scherlacher A, Beaufort- Spontin F: Radiotherapy of head and neck neoplasms:Prevention of inflammation of the mucosa by sucralfate treatment. (pdftreatment.com)
6][7][8] In addition, pathogenic organisms such as viruses, toxic chemical compounds, and radiation can also lead to cancer pathogenesis by promoting inflammation in the cells. (researchgate.net)

Differences in tumor type, the extent of the cancer, type of radiation used, and the total amount of radiation prescribed can affect chances of developing complications. (healthybladderclub.com)
Radiation necrosis is part of a series of clinical syndromes related to CNS complications of radiotherapy. (medscape.com)
Early delayed complications occur 1-4 months after radiotherapy. (medscape.com)
Radiation necrosis and diffuse cerebral atrophy are considered long-term complications of radiotherapy that occur from months to decades after radiation treatment. (medscape.com)

It is important to distinguish the radiosensitivity of a particular tumor, which to some extent is a laboratory measure, from the radiation "curability" of a cancer in actual clinical practice. (wikipedia.org)
In this consensus paper, experts from the Taiwan Society for Therapeutic Radiology and Oncology and Taiwan Society of Cardiology provide a focused update on the clinical practice for risk stratification and management of radiation-induced cardiovascular disease (RICVD). (tmu.edu.tw)
Gold nanoparticles (AuNPs) have recently attracted attention as clinical agents for enhancing the effect of radiotherapy in various cancers. (tmu.edu.tw)
Although radiotherapy is a standard treatment for cancers, invasive recurrence and metastasis are significant clinical problems. (tmu.edu.tw)
Thus, these findings provide a possible clinical strategy for using AuNPs to treat invasive breast cancer following radiotherapy. (tmu.edu.tw)
This issue is extremely relevant given the growing number of clinical trials testing the ability of radiotherapy to increase the efficacy of ICBs. (aacrjournals.org)
Here, we discuss the rationale for an optimized use of radiotherapy as well as candidate biomarkers that may predict clinical responses to radiotherapy combined with ICBs. (aacrjournals.org)
In the clinical situation of a recurrent astrocytoma (postradiation therapy), radiation necrosis presents a diagnostic dilemma. (medscape.com)
In the struggle to treat life-threatening COVID-19 pneumonia, scientists have debated the clinical use of ionizing radiation (IR). (bvsalud.org)

Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is a treatment using ionizing radiation, generally provided as part of cancer therapy to either kill or control the growth of malignant cells. (wikipedia.org)
Brachytherapy, in which a radioactive source is placed inside or next to the area requiring treatment, is another form of radiation therapy that minimizes exposure to healthy tissue during procedures to treat cancers of the breast, prostate, and other organs. (wikipedia.org)
Radiation therapy has several applications in non-malignant conditions, such as the treatment of trigeminal neuralgia, acoustic neuromas, severe thyroid eye disease, pterygium, pigmented villonodular synovitis, and prevention of keloid scar growth, vascular restenosis, and heterotopic ossification. (wikipedia.org)
Radiation therapy (RT), one of the pillars of cancer treatment, directly causes DNA damage, which can lead to senescence and cell death in tumor cells. (elsevierpure.com)
Radiotherapy is an indispensable component of cancer treatment, and irradiation of the heart and vasculature during cancer radiotherapy is now recognized as a new risk factor for cardiovascular diseases. (tmu.edu.tw)
Cell growth/cell death and endpoints related to accumulation of DNA damage and, thus, carcinogenesis, were studied up to 21 days post treatment in cells exposed to radiation and the lowest cisplatin doses. (bvsalud.org)
Furthermore, double strand DNA breaks were induced in every patient 30 min after the treatment and remaining DNA repair and damage signaling continued after 18-24 h. (itg.be)
Since facilitating information access continues to evolve in radiation oncology on a regular basis, this issue's Technology Trends explores advances in treatment planning systems and discusses the need to balance automation with personalization. (appliedradiationoncology.com)
Moreover, the invasive activity of breast cancer cell lines after radiation treatment was significantly inhibited in the presence of RGD/P-AuNPs. (tmu.edu.tw)
Recent reports have shown that neutron-based radiation therapy may be more effective than photon-based radiation therapy for the treatment of malignant salivary gland neoplasms with gross disease and provides excellent local and regional control of microscopic disease. (medscape.com)
Glioblastoma (GBM) is uniformly fatal with a median survival of just over 1 year, despite best available treatment including radiotherapy (RT). (elsevierpure.com)
For this study, SUPR (simple unplanned palliative radiotherapy) refers to the delivery of radiation to the treatment area with a simple technique, either two opposed fields (parallel opposed pair), or a single direct field. (centerwatch.com)
All RT in the province is provided by 6 centres where radiation oncologists receive an annual salary, which are independent of RT treatment technique and duration. (centerwatch.com)
MASTECTOMY) or radiation treatment of breast cancer. (bvsalud.org)
Treatment of late radiation cystitis is challenging. (healthybladderclub.com)
To find out more about radiation cystitis treatment and various other HBOT treatment options, give us a call or visit your nearest location. (healthybladderclub.com)
Radiation treatment is useful in fighting cancer because it can interfere with the DNA of the cancer cells and stop them from rapidly dividing and replicating. (healthybladderclub.com)

Radiotherapy for head and neck cancers has been examined as a possible risk factor for second primary cancers, but the results have been equivocal. (nih.gov)
According to this study, using sucralfate in order to decrease radiation-induced side effects in head and neck cancers not only is ineffective in reducing radiation mucositis and other side effects but also induces nausea and vomiting. (pdftreatment.com)
Radiation-induced hyposalivation is a common complication of radiotherapy for head and neck cancers. (ac.ir)
Haddad P, Karimi M. A randomized, double-blind, placebo-controlled trial of concomitant pilocarpine with head and neck irradiation for prevention of radiation-induced xerostomia. (ac.ir)

Acute encephalopathy occurs during and up to 1 month after radiotherapy. (medscape.com)

A late effect of ionizing radiation is the development of sarcoma within the field of irradiation, referred to as postradiation sarcoma (PRS) or radiation-induced sarcoma (RIS). (medscape.com)
Ionizing radiation has had many varied uses in medicine. (medscape.com)
Ionizing radiation is thought to act via genetic alterations, including mutations of p53 and retinoblastoma (Rb) genes. (medscape.com)
Whereas ionizing radiation is the triggering factor (with 40-60 Gy believed to be the threshold dose), other factors (eg, genetic tendency, concomitant use of chemotherapeutic agents, and various factors as yet unknown) appear to be responsible for the development of PRS. (medscape.com)
Ionizing radiation works by damaging the DNA of cancerous tissue leading to cellular death. (wikipedia.org)
Diagnostic and therapeutic ionizing radiation (IR) is one of the well known long term risk factors of breast cancer. (biomedcentral.com)
Some additional studies were also performed: measurement of fullerenol nanoparticle size, zeta potential, and the influence of fullerenol on the ionizing radiation-induced damage to PMBCs. (biofullerene.com)
1998. Food preservation using ionizing radiation. (cdc.gov)

inflammatory breast neoplasms, medical oncology. (bvsalud.org)

We evaluated the impact of therapeutic radiation for oral cancer on the risk of second primary cancers with data from the Surveillance, Epidemiology, and End Results (SEER) program for 1973-1999. (nih.gov)
Radiation therapy may be curative in a number of types of cancer if they are localized to one area of the body, and have not spread to other parts. (wikipedia.org)
Most common cancer types can be treated with radiation therapy in some way. (wikipedia.org)
The response of a cancer to radiation is described by its radiosensitivity. (wikipedia.org)
Highly radiosensitive cancer cells are rapidly killed by modest doses of radiation. (wikipedia.org)
Implications of new data on radiation cancer risk : proceedings of the Thirty-second Annual Meeting, 3-4 April 1996, as presented at the Crystal City Marriott, Arlington, Va. / John D. Boice, editor. (who.int)
[ 9 ] and gynecologic cancer, the excess does not appear to be strongly related to radiotherapy. (medscape.com)
This study evaluated the effect of matrix metalloproteinases-2 (MMP-2) gene silencing using MMP-2 shRNA expression plasmids (pMMP-2) on IR induced cytotoxicity and DNA damage by MTT, dead green, γH2AX and comet assays in human normal dermal fibroblasts (HDFs) and MCF-7 human breast cancer cells. (biomedcentral.com)
Several studies have suggested that radiation promotes the invasion of cancer cells by activating molecular mechanisms involving integrin and fibronectin (FN). (tmu.edu.tw)
A combination of RGD/P-AuNPs and radiation reduced cancer cell viability and increased DNA damage compared to radiation alone in MDA-MB-231 cells. (tmu.edu.tw)
Our study suggests that RGD/P-AuNPs can target integrin-overexpressing cancer cells to improve radiation therapy by suppressing invasive activity in addition to sensitization. (tmu.edu.tw)
On the basis of our finding that, integrin α6β4 is specifically activated and acts primarily to induce premature senescence in irradiated cancer cells, we propose that this integrin may be a valuable target and biomarker for radiotherapy. (korea.ac.kr)
Recent data demonstrate that the recruitment of dendritic cells to neoplastic lesions (and hence the priming of tumor-specific CD8 + T cells) is highly dependent on radiotherapy dose and fractionation through a mechanism that involves the accumulation of double-stranded DNA in the cytoplasm of cancer cells and consequent type I IFN release. (aacrjournals.org)
However, radiation can also have the same effect on healthy, normal tissue surrounding the cancer. (healthybladderclub.com)
Radiation therapy is an important therapeutic option for many people dealing with the difficulties of cancer and it can provide great outcomes with limited adverse effects, said Jerry George, DO , oncologist. (healthybladderclub.com)
Effectiveness of postoperative radiotherapy after radical cystectomy for locally advanced bladder cancer. (musc.edu)
Research activities involve the use of radiation and cancer cytogenetics, molecular genetics and radioisotope methodologies to study questions of basic and applied research in radiation protection, radiobiology, and cancer genetics. (demokritos.gr)
It has been suggested that radiation sensitivity and chemosensitivity of cancer cells may play an important role in the local control of the tumor following these therapies. (researchsquare.com)
We identify details including the computed tomography (CT) scanning considerations, the radiobiological basis of IR anti-inflammatory effects, the supportive evidence for low dose radiation therapy (LDRT), and the risks of radiation-induced cancer and cardiac disease associated with LDRT. (bvsalud.org)
This study aimed to estimate cancer risks induced by lung LDRT for different radiotherapy delivery techniques. (bvsalud.org)
The radiation-induced cancer incidence and cancer-specific mortality, and cardiac heart disease risks were estimated for the assessed techniques. (bvsalud.org)
CONCLUSION: All the radiotherapy techniques had low cancer risks. (bvsalud.org)
One study further identified that WISP2 expression was enhanced by serum and correlated with serum-induced cell proliferation in breast cancer cells, demonstrating that WISP2 could enhance cell proliferation in breast cancer [ 8 ]. (biomedcentral.com)

Total body irradiation (TBI) is a radiation therapy technique used to prepare the body to receive a bone marrow transplant. (wikipedia.org)
The lesion arises in the area of previous radiation, with an interval between irradiation and the development of the new tumor of approximately 10 years. (medscape.com)
It uses multiple radiation beams targeted to the tumor, however, large volumes of the body receive low doses of irradiation. (itg.be)
Group I was treated with external radiotherapy alone and group II received irradiation and oral sucralfate. (pdftreatment.com)
The total dose of radiation was at least 50 Gy and sucralfate was started at the beginning of irradiation and was continued for 9 weeks at an oral dose of 1 gram, three times a day. (pdftreatment.com)

Histopathological analysis revealed sheets and aggregates of neoplasm replacing bone marrow interspersed with sclerotic bony fragments. (hindawi.com)

The goal is to deliver a conformal radiation dose to the target volume with maximal sparing of the normal tissue. (centerwatch.com)

Radiation necrosis, a focal structural lesion that usually occurs at the original tumor site, is a potential long-term central nervous system (CNS) complication of radiotherapy or radiosurgery. (medscape.com)

However, in cases of accidental exposure to ionising radiation, the culturing of lymphocytes to obtain metaphase chromosomes and analysis of chromosomal aberrations is time-consuming and problematic after high radiation doses. (bvsalud.org)
HPRC has been the Reference Laboratory of the Greek Atomic Energy Commission and the International Atomic Energy Agency (IAEA) for biological dosimetry and the evaluation of absorbed doses in cases of radiation accident, as well as for standardization of state of the art methodologies applied for biodosimetry purposes. (demokritos.gr)

The primary objective is to patient-reported Quality of Life related to complete control of Radiation Induced Nausea and Vomiting (RINV) between standard palliative radiotherapy and VMAT. (centerwatch.com)

Radiation exposure, known to cause DNA damage, may be a potential source of field cancerization of the upper aerodigestive tract. (nih.gov)
In conclusion, fractionated, concomitant exposure to radiation and cisplatin reduces the inhibitory effect of radiation on cell proliferation of normal cells and does not potentiate delayed effects resulting from accumulation of DNA damage. (bvsalud.org)
Î³H2AX foci induced by mixed beam radiation tended to be surrounded by open chromatin (lighter TEM regions), yet foci containing the highest number of beads, i.e. larger foci representing complex damage, remained in the heterochromatic areas. (bvsalud.org)
IR induced DNA damage in both HDFs and MCF-7 cells. (biomedcentral.com)
The results conclude that pMMP-2 has protected HDFs and sensitized the MCF-7 cells from IR induced DNA damage. (biomedcentral.com)
The aim of the present investigation is to study the effect of MMP-2 gene silencing by transfection of MMP-2 shRNA expression plasmids (pMMP-2on radiation-induced DNA damage in human normal dermal fibroblasts (HDFs) and MCF-7 cells. (biomedcentral.com)
1993. Protective effects of chlorogenic acid, curcumin and beta-carotene against gamma-radiation-induced in vivo chromosomal damage. (cdc.gov)

The use of radiation therapy in non-malignant conditions is limited partly by worries about the risk of radiation-induced cancers. (wikipedia.org)
Different cancers respond to radiation therapy in different ways. (wikipedia.org)
The majority of epithelial cancers are only moderately radiosensitive, and require a significantly higher dose of radiation (60-70 Gy) to achieve a radical cure. (wikipedia.org)
Combining radiation therapy with immunotherapy is an active area of investigation and has shown some promise for melanoma and other cancers. (wikipedia.org)

However, a single dose or fractionated dose of radiation has severe effects on the adjacent normal tissue during radiotherapy [ 2 ]. (biomedcentral.com)

More studies have quantified the use of radiotherapy in the postoperative setting. (medscape.com)
Nonetheless, prospective randomized controlled studies are needed to confirm the usefulness of postoperative radiotherapy. (medscape.com)
This is often combined with postoperative radiation therapy, depending on the specific tumor characteristics and stage. (medscape.com)

10]Burch RM, McMillan BA: Sucralfate induces proliferation of dermal fibroblasts and keratinocytes in culture and granulation tissue formation in full thickness skin wounds. (pdftreatment.com)
Tumor-promoting CNS injury responses are recapitulated in the tumor microenvironment and augmented following prior radiation, impacting cell phenotype, proliferation, and infiltration in the CNS. (elsevierpure.com)

12]Epstein JB, Wong FLW: The efficacy of sucralfate suspension in the prevention of oral mucositis due to radiation therapy. (pdftreatment.com)
La mucositis oral (MO) representa una afección inflamatoria frequente em pacientes oncológicos e uma higiene oral insatisfatória tem frecuente en pacientes con cáncer, y la mala higiene bucal se ha relacionado sido relacionada como fator predisponente para o seu surgimento. (bvsalud.org)

Newer trials with antimicrotubule agents with and without concomitant radiotherapy have shown efficacy. (medscape.com)

By means of different bioinformatics analyses, we report that IMRT induced an inflammatory response via the induction of viral, adaptive, and innate immune signaling. (itg.be)

Purpose: To quantify proton radiotherapy dose reduction in the prostate target volume because of the three-dimensional movement of the prostate based on an analysis of dose-volume histograms (DVHs). (korea.ac.kr)

The diagnosis mandates that the lesion must have proven histologic differences from the primary neoplasm (carcinomas, lymphomas). (medscape.com)

Here we show that the activation of integrin β4 is essential for IR-induced cellular senescence. (korea.ac.kr)
We suggest that insights from RT-induced changes in the tumor microenvironment may provide opportunities to target mechanisms, such as cellular senescence, that may promote GBM aggressiveness amplified in previously radiated microenvironment. (elsevierpure.com)

However, the impact of dose and fractionation on the immunostimulatory potential of radiotherapy has not been thoroughly investigated. (aacrjournals.org)

[ 10 ] Despite significant medical use of radiation therapy (RT), PRS is an uncommon tumor. (medscape.com)
Radiation therapy is commonly applied to the cancerous tumor because of its ability to control cell growth. (wikipedia.org)
For example, leukemias are not generally curable with radiation therapy, because they are disseminated through the body. (wikipedia.org)
Early-stage, localized disease may be treated with radiation therapy or excision in certain cases. (medscape.com)
A relationship between increased blood-brain barrier permeability and radiation therapy has been posited to contribute to this leukoencephalopathy and to methotrexate-induced vasculopathy. (medscape.com)
A serious radiation protection concern is therefore rising with respect to the use of proton radiation therapy. (su.se)

It can occur secondary to any form of radiotherapy modality or regimen. (medscape.com)

1% Pilocarpine mouthwash is recommended for managing radiation-induced xerostomia. (ac.ir)

The subspecialty of oncology concerned with radiotherapy is called radiation oncology. (wikipedia.org)

Anatomy4

Organisms1

Diseases113

Chemicals and Drugs31

Analytical, Diagnostic and Therapeutic Techniques and Equipment77

Phenomena and Processes20

Disciplines and Occupations5

Anthropology, Education, Sociology and Social Phenomena2

Technology, Industry, Agriculture1

Humanities1

Information Science6

Named Groups1

Health Care34

Chemotherapy17

Malignant neoplasm3

Carcinoma3

Effects of radiotherapy2

Patients35

Toxicity7

Etiology1

Image-Guided Radiotherapy1

Urinary Bladder Neoplasms3

Intensity-Modulated Radiotherapy1

Stereotactic Ablative Radiotherapy1

Humans2

Tumors6

Apoptosis2

20222

Adjuvant2

Chemo-therapy3

Systematic Review1

Computerized tomography1

Malignancies3

Inflammation2

Complications4

Clinical9

Treatment17

Head and neck4

Acute1

Ionizing Radiation8

Medical oncology1

Cancer23

Irradiation5

Bone Marrow1

Conformal1

Complication1

Doses2

VMAT1

Damage7

Cancers4

Dose of radiation1

Postoperative3

Proliferation2

Mucositis2

Concomitant1

IMRT1

Prostate1

Histologic1

Senescence2

Fractionation1

Therapy6

Secondary1

Xerostomia1

Called radiation oncology1