Radiation genetics. Medical search. Frequent questions

Your degree and research area is bespoke to you, however, our supervisors can provide projects in many areas of current interest in genetics and genomics, ranging from fundamental questions in cell biology to variation and disease in humans. (nottingham.ac.uk)
156 (9.9%) were identified as human genomics/genetics publications. (cdc.gov)
All human genomics/genetics articles were coded according to topic and phase of translational research . (cdc.gov)
Genetics, genomics and the patenting of DNA : review of potential implications for health in developing countries. (who.int)

The smaller tumors are usually treated with surgery, but if the tumor is larger than two inches, radiation therapy or chemotherapy may be used. (naturalpedia.com)
Treatment for sarcomas such as MFH, usually involves surgical removal of the tumor, followed by radiation or chemotherapy to kill off any remaining cancer cells. (naturalpedia.com)
You'd have surgery to remove a tumor, then chemotherapy or radiation to kill cancer cells. (webmd.com)
Tumor genetics can also tell doctors which drugs won't work. (webmd.com)
This may be due to radiation treatment, chemotherapy, or a brain tumor or its treatment. (kidshealth.org)

For instance, we might expect evolutionary change in adaptive radiations to be driven by the availability of ecological niches. (nih.gov)
Understanding the genetic basis of speciation and adaptive radiation without geographic isolation, and determining how and when such diversification is possible, is a key aim of evolutionary biology. (biorxiv.org)

We applied two tests for the assumption of Brownian motion that generally have high power to reject data generated under non-Brownian niche-filling models for the evolution of traits in adaptive radiations. (nih.gov)
Adaptive radiations represent some of the most remarkable explosions of diversification across the tree of life. (biorxiv.org)
These results highlight the role of both genome architecture and secondary contact with hybridization in fuelling adaptive radiation. (biorxiv.org)
Despite the supposed prevalence of ecological speciation in adaptive radiation, the factors that constrain or facilitate speciation and the mechanisms by which speciation proceeds during the adaptive radiation of lineages are still not well understood 3 , 4 . (biorxiv.org)

A few women develop uterine sarcoma 5 to 25 years after they had radiation therapy for another pelvic cancer. (medlineplus.gov)
Depending on the results, you may need radiation therapy or chemotherapy to kill any cancer cells that remain. (medlineplus.gov)
With cancer that has come back, radiation may be used for palliative treatment . (medlineplus.gov)
If you have had radiation therapy in your pelvic area or have taken tamoxifen for breast cancer, ask your provider how often you should be checked for possible problems. (medlineplus.gov)
Epidemiological studies with longer follow-up of larger cohorts of pilots with a wide range of radiation exposure levels are needed to clarify the relationship between cosmic radiation exposure and cancer risk. (cdc.gov)
One other way that these hormonal problems can arise is as a side-effect of radiotherapy, more specifically, radiation used to prevent the spread of cancer to the brain. (catalyst-magazine.org)
Chemotherapy and radiation may be used after surgery to make sure all the cancer cells are killed. (naturalpedia.com)
Exposure to radiation from atomic bombs, nuclear accidents, and prior cancer treatment may affect risk. (medicalnewstoday.com)
Estimation of organ-specific occupational radiation doses for individual technologists using these data (in progress) will be used in comprehensive retrospective and prospective investigations of radiogenic cancer and other serious disease risks. (bmj.com)
The Jackson Laboratory has made fundamental contributions to biomedical research, including cancer genetics and establishing the mouse as the premier research animal model. (jax.org)
Eight employees and $50,000, 'For research in cancer and the effects of radiation. (jax.org)
Over half of cancer patients undergo radiation therapy (RT). (nature.com)

Genetics to include, inheritance patterns, mutations and clinical application to practice and oncogenetics. (bangor.ac.uk)

Population genetics studies the genetic variation that exists in wild populations, and the forces, such as selection, mutation and genetic drift, that shape this variation. (nottingham.ac.uk)

Unlike non- ionizing radiation (such as microwaves and ultraviolet radiation), which has insufficient energy to eject molecular electrons, ionizing radiation deposits sufficient energy to remove electrons from atomic orbits and create molecular ion pairs along particle tracks. (cdc.gov)
Eumelanin also protects skin from damage caused by ultraviolet (UV) radiation in sunlight. (medlineplus.gov)
others are sparked by environmental exposures such as ultraviolet radiation, tobacco smoke or chemicals. (columbian.com)
Eumelanin also absorbs damaging ultraviolet radiation. (leakeyfoundation.org)

NIEHS research uses state-of-the-art science and technology to investigate the interplay between environmental exposures, human biology, genetics, and common diseases to help prevent disease and improve human health. (nih.gov)

But blasting cancers with chemotherapy or radiation kills healthy cells as well, which can lead to a host of nasty side effects. (webmd.com)
Chemotherapy and radiation both work by killing fast-growing cells. (kidshealth.org)
Some chemotherapy drugs and/or radiation to the brain may interfere with learning. (kidshealth.org)
Chemotherapy, radiation to the brain, and even some antibiotics can lead to high-frequency hearing loss (when a person cannot hear high-pitched sounds), tinnitus (ringing in the ears), or dizziness. (kidshealth.org)
Short dental roots, delayed teeth, or missing teeth are more common in very young children who've had radiation to the brain and/or chemotherapy with a drug called vincristine. (kidshealth.org)
Both chemotherapy and radiation can cause fertility problems . (kidshealth.org)

The discussion below largely relates to lower radiation doses and dose rates which can cause non-deterministic effects and which are more relatable to radiation exposure from NPL sites. (cdc.gov)

We also have an excellent understanding of mouse biology, including their genetics, which means experiments can be performed under well-defined conditions (meaning it is easier to make a link between causes and effects in experiments). (catalyst-magazine.org)

this process, called "ionization," is the source of the term "ionizing radiation" (see Chapter 2). (cdc.gov)

z-VAD-fmk was injected intracerebroventricularly as a bolus injection (0.2 µg/h for 1 h) into rats prior to exposure to radiation. (spandidos-publications.com)

To whom correspondence should be addressed: St. John's Institute of Dermatology, Division of Genetics and Molecular Medicine, King's College London School of Medicine at Guy's, King's College and St. Thomas' Hospitals, King's College London (KCL), University of London, St. Thomas' Hospital, Lambeth Palace Road, London SE1 7EH, United Kingdom. (bioone.org)

As a case study, we used these tests to explore the evolution of feeding adaptations in two radiations of warblers. (nih.gov)
The research group Genetics of Sex Differences is interested in sexual selection and sexual conflict, the evolution of sexual dimorphism, and sex chromosome evolution. (lu.se)

A mammogram is an X-ray with low-dose radiation that lets doctors look for abnormalities in the breast tissue. (everydayhealth.com)

Here, we address these questions in the Alpine whitefish radiation, using a whole-genome dataset that includes multiple individuals of each of the 22 species belonging to six ecologically distinct ecomorph classes across several lake-systems. (biorxiv.org)

Investigating brain stem cells using mouse genetics, microscopes, and radiation. (catalyst-magazine.org)

Past radiation therapy. (medlineplus.gov)
Radiation therapy is a major risk factor for all soft tissue sarcomas, including MFH. (naturalpedia.com)
Treatment for this condition includes surgery and radiation therapy. (kaiserpermanente.org)

A number of direct and indirect radiation interaction pathways can produce damage to the DNA of irradiated cells. (cdc.gov)

It has lower radiation than normal X-Rays. (healthline.com)

Depending on their genetics, people produce different amounts of eumelanin. (leakeyfoundation.org)

Direct macromolecule damage by radiation involves partial or complete energy transfer to one or more electrons on the molecule. (cdc.gov)

A very large radiation dose received in a short enough period of time to preclude significant repair can cause cellular walls to collapse and disrupt organ systems, producing deterministic effects such as acute radiation syndrome, cataracts, and teratogenesis (mental retardation, IQ reduction, microencephaly, stunted growth). (cdc.gov)
Irradiation was conducted at room temperature at a dose of radiation of 4 Gy. (spandidos-publications.com)

Kids who had chest radiation and/or chemo with a class of drugs called anthracycline are at higher risk for heart problems up to 20 years or longer after treatment. (kidshealth.org)
Because pheomelanin does not protect skin from UV radiation, people with more pheomelanin have an increased risk of skin damage caused by sun exposure. (medlineplus.gov)
Skin damage caused by UV radiation from the sun is a major risk factor for developing melanoma. (medlineplus.gov)
Studies suggest that other variations in the MC1R gene may also increase the risk of developing melanoma in the absence of UV radiation-related skin damage. (medlineplus.gov)

Later, more sophisticated techniques such as gamma and neutron radiation were developed at newly established nuclear research centers. (hindawi.com)
Airborne contamination at these areas consists of both gamma radiation and Rn-222. (cdc.gov)
At the SLAPS, the gamma exposure rate has been measured at 9 to 261 x 10 -6 roentgens per hour (R/hr, a roentgen is a unit of radiation exposure), with an average of 84 x 10 -6 R/hr taken along the northern boundary ( Bechtel, 1987c ). (cdc.gov)
In 1988, gamma radiation measurements showed a radiation exposure rate ranging from 17 to 2,229 x 10 -3 R/yr above a bkg average of 73x10 -3 R/yr ( Bechtel, 1989a ). (cdc.gov)
Gamma radiation readings at the site during 1988 ranged from 13 to 55 x 10 -6 R/hr with an average exposure rate of 24 x 10 -6 R/hr with the bkg in the St. Louis area of 8 x 10 -6 R/hr. (cdc.gov)

Blurred or double vision, glaucoma, or cataracts are more likely in kids who were treated for tumors near the eye or received radiation to the brain. (kidshealth.org)

Antony R. Young and Susan L. Walker "UV Radiation, Vitamin D and Human Health: An Unfolding Controversy Introduction," Photochemistry and Photobiology 81(6), 1243-1245, (1 November 2005). (bioone.org)

These effects can be caused by acute exposure to sources of high intensity radiation, such as can be found in hospitals, government, and industry. (cdc.gov)
Because eumelanin normally protects skin from the harmful effects of UV radiation, a lack of this pigment leaves skin more vulnerable to damage from sun exposure. (medlineplus.gov)
Healthy male Sprague‑Dawley rats were used in the present study to examine the radioprotective effect of a type of pan-caspase inhibitor, z-VAD-fmk, following radiation, to investigate the effects of caspase blockade in a model of the nucleus of the abducens nerve. (spandidos-publications.com)

Studies on the molecular mechanism of neuronal cell apoptosis following radiation have enriched the number of protective therapeutic strategies against radiation-induced neuronal cell death ( 2 ). (spandidos-publications.com)

The School of Life Sciences has many research groups doing pioneering work in genetics, ranging across a broad diversity of relevant topics. (nottingham.ac.uk)

These include age, gender, and genetics. (healthline.com)

The present study performed immunohistochemistry, terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) and western blot analysis and identified no significant changes in the expression of the X-linked inhibitor of apoptosis protein (XIAP) following radiation (P>0.05). (spandidos-publications.com)

As a result, the present study aimed to investigate changes in the expression of X-linked IAP (XIAP) induced by radiation injury, the activity and expression of caspase members following radiation and the effect of caspase blockade. (spandidos-publications.com)

The syndrome has been documented for 50 years, but more recent developments in molecular genetics have dramatically increased understanding of its pathophysiology and opened up molecular avenues for treatment in the future. (medscape.com)
The severity of the problem depends on how much chemo and/or chest radiation they got and the child's age during treatment. (kidshealth.org)
For example, doctors may shield the ovaries and testicles during radiation treatment. (kidshealth.org)

Anatomy1

Diseases10

Chemicals and Drugs2

Analytical, Diagnostic and Therapeutic Techniques and Equipment9

Psychiatry and Psychology1

Phenomena and Processes10

Disciplines and Occupations5

Health Care10

Genomics4

Tumor5

Evolutionary2

Adaptive4

Cancer12

Mutations1

Population Genetics1

Ultraviolet4

Exposures1

Chemotherapy6

Doses1

Biology1

Ionizing1

Exposure to radiation1

Molecular Medicine1

Evolution2

Abnormalities1

Genome1

Stem cells1

Therapy3

Pathways1

Lower radiation1

Depending1

Involves1

Dose2

Risk4

Gamma5

Tumors1

INTRODUCTION1

Effects3

Therapeutic1

Research1

Include1

Protein1

Investigate1

Treatment3