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Racemases and EpimerasesCarbohydrate EpimerasesAlanine RacemaseAmino Acid IsomerasesUDPglucose 4-EpimeraseCarbohydratesCarbohydrate MetabolismDietary CarbohydratesMolecular Sequence DataPlesiomonasAmino Acid SequenceAzotobacter vinelandiiIduronic AcidHexuronic AcidsUronic AcidsGlucuronic AcidCarbohydrate SequenceAlginatesSubstrate SpecificityCarbohydrate ConformationCrystallography, X-RaySequence AlignmentModels, MolecularPhylogenySequence Homology, Amino AcidKineticsBacterial ProteinsOligosaccharidesCloning, MolecularAntigens, Tumor-Associated, CarbohydrateLectins
Ribulose 5-phosphaIsomerasesMetabolismEnzymesPentoseLipidFattyFamilyActing on carbohydrates and derivativesIsomeraseGlucoseClass
Ribulose 5-phospha8
  • In enzymology, a L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4) is an enzyme that catalyzes the interconversion of ribulose 5-phosphate and xylulose 5-phosphate in the oxidative phase of the Pentose phosphate pathway. (wikipedia.org)
  • The systematic name of this enzyme class is L-ribulose-5-phosphate 4-epimerase. (wikipedia.org)
  • Other names in common use include phosphoribulose isomerase, ribulose phosphate 4-epimerase, L-ribulose-phosphate 4-epimerase, L-ribulose 5-phosphate 4-epimerase, AraD, and L-Ru5P. (wikipedia.org)
  • Mechanism of ribulose 5-phosphate 4-epimerase in active site Aldol and dehydration mechanisms L-Ribulose 5-phosphate 4-epimerase catalyzes the epimerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate by retro-aldol cleavage and subsequent aldol reaction. (wikipedia.org)
  • First, the retro-aldol cleavage mechanism is analogous to the reaction catalyzed by L-fuculose-phosphate aldolase which has high levels of sequence similarity with L-ribulose-5-phosphate 4-epimerase. (wikipedia.org)
  • Ribulose 5-phosphate 4-epimerase is found on the well studied L-arabinose operon. (wikipedia.org)
  • This operon consists of eight genes araA-araH with the gene for Ribulose 5-phosphate 4-epimerase called araD. (wikipedia.org)
  • L-Ribulose-5-phosphate 4-epimerase and L-fuculose-1-phosphate (L-Fuc1P) aldolase are evolutionarily related enzymes that display 26% sequence identity and a very high degree of structural similarity. (wikipedia.org)
Isomerases2
Metabolism2
  • IBS further showed transcriptional upregulation of enzymes involved in fructose and glucan metabolism as well as the succinate pathway of carbohydrate fermentation. (biomedcentral.com)
  • Galactosemia is an inborn disorder of carbohydrate metabolism of which early detection can prevent severe illness. (bvsalud.org)
Enzymes1
  • This is consistent with the notion that both enzymes belong to a superfamily of epimerases/aldolases that catalyze carbon-carbon bond cleavage reactions via a metal-stabilized enolate intermediate. (wikipedia.org)
Pentose1
  • 2. Dickens, F. and Williamson, D.H. Pentose phosphate isomerase and epimerase from animal tissues. (qmul.ac.uk)
Lipid1
  • Although lipids are a distinct class of biomolecules, we shall see that they often occur combined, either covalently or through weak bonds, with members of other classes of bio-molecules to yield hybrid molecules such as glycolipids , which contain both carbohydrate and lipid groups, "and lipoproteins , which contain both lipids and proteins. (medmuv.com)
Fatty1
  • For example, carbohydrase can break down carbohydrates into sugars, lipase can break down fats into fatty acids and protease breaks down protein into amino acids. (priyamstudycentre.com)
Family1
  • N-terminal domain, C-terminal domain, FGGY family of carbohydrate kinases [InterProScan]. (ntu.edu.sg)
Acting on carbohydrates and derivatives1
Isomerase1
  • Other names in common use include phosphoribulose isomerase, ribulose phosphate 4-epimerase, L-ribulose-phosphate 4-epimerase, L-ribulose 5-phosphate 4-epimerase, AraD, and L-Ru5P. (wikipedia.org)
Glucose1
  • Accepted August 23, 2012 ABSTRACT The catabolite control protein CcpA is a pleiotropic regulator that mediates the global transcriptional response to rapidly catabolizable carbohydrates, like glucose in Gram-positive bacteria. (studyres.com)
Class1
  • The systematic name of this enzyme class is L-ribulose-5-phosphate 4-epimerase. (wikipedia.org)