Amyloid beta-Protein PrecursorAmyloid beta-PeptidesAmyloidMicrogliaAlzheimer DiseasePeptide FragmentsProtein PrecursorsAmyloid Precursor Protein SecretasesSmilacaceaeAmino Acid SequenceMolecular Sequence DataPlaque, AmyloidEndopeptidasesAspartic Acid EndopeptidasesCerebral Amyloid AngiopathyAmyloid NeuropathiesBrainMoraceaeIridoid GlycosidesNeuronsCells, CulturedCell LineSerum Amyloid A ProteinMice, TransgenicCell MembraneBase SequenceProtein Processing, Post-TranslationalMolecular WeightElectrophoresis, Polyacrylamide GelIntracellular MembranesMembranesCerebral CortexKineticsRecombinant ProteinsBinding SitesDisease Models, AnimalProtein BindingCloning, MolecularMembrane LipidsMutationTrypsinRNA, MessengerPeptide HydrolasesPeptidesAmyloidosisProtein ConformationProtein Structure, TertiaryBlotting, WesternEscherichia coliIslet Amyloid PolypeptideMembrane PotentialsHydrolysisMembranes, ArtificialTransfectionAgingInterleukin-1betaMicroscopy, ElectronMembrane ProteinsSequence Homology, Amino AcidModels, MolecularSerine EndopeptidasesProtein Structure, SecondaryPresenilin-1ChymotrypsinCarrier ProteinsRecombinant Fusion ProteinsCattleTime FactorsCricetinaeMice, Inbred C57BLDNAImmunoblottingProtease InhibitorsInsulysinSubstrate SpecificitySignal TransductionPlasmidsDNA PrimersNerve Tissue ProteinsErythrocyte MembraneStructure-Activity RelationshipProteolysisImmunohistochemistryMacromolecular SubstancesEnzyme PrecursorsGene Expression RegulationCongo RedMembrane GlycoproteinsMembrane FluiditySerum Amyloid P-ComponentAntibodies, MonoclonalBacterial ProteinsCircular DichroismGlycoproteinsCysteine EndopeptidasesS100 Calcium Binding Protein beta SubunitProtein TransportMass SpectrometryGene ExpressionProteins