• As such, an extract of HGW a was examined by first characterizing it via high performance liquid chromatography (HPLC) to determine the presence of icariin, epimedins A, B and C, icaritin (i.e., fully deglycosylated icariin) and hyperoside (galactoside of quercetin). (cosmeticsandtoiletries.com)
  • The effect of quercetin on the prevention or treatment of COVID-19 and other respiratory tract infections in humans: A rapid review, Adv. Integr. (c19early.org)
  • Binding interaction of quercetin-3-beta-galactoside and its synthetic derivatives with SARS-CoV 3CL(pro): Structure-activity relationship studies reveal salient pharmacophore features, Bioorg. (c19early.org)
  • The material was then tested in vitro for biofilm reduction and anti-inflammatory effects. (cosmeticsandtoiletries.com)
  • QR is an active agent against SARS and MERS due to its antimicrobial, antiviral, anti-inflammatory, antioxidant, and some other beneficial effects. (c19early.org)
  • Overall, the results indicate that epigallocatechin gallate and withaferin A, in combination, may potentially inhibit skin-aging, while enhancing antioxidant effects of various enzymes, and warrant further experimental validation. (ijpsonline.com)
  • QR may hold therapeutic potential against SARS-CoV-2 due to its inhibitory effects on several stages of the viral life cycle. (c19early.org)
  • Many studies have investigated the cardioprotective effect of phytochemicals against CH by abrogating oxidative stress and inflammation. (phcogrev.com)
  • N. Nasiruddin , " Protective Effects of Phytochemicals against Cardiac Hypertrophy by Modulating Oxidative Stress and Inflammation: A Review " , Pharmacognosy Reviews , vol. 16, no. 32, pp. 146-151, 2022. (phcogrev.com)
  • Neuroprotective effects of salidroside and its analogue tyrosol galactoside against focal cerebral ischemia in vivo and H2O2-induced neurotoxicity in vitro. (ac.ir)
  • In vitro effects of PCBs and OH-PCBs on the basal and dexamethasone-modified thyroid hormone metabolism in chicken liver. (krakow.pl)
  • Aging has many adverse effects on human health. (frontiersin.org)
  • However, concerns have been raised about potential adverse effects. (healthline.com)
  • Public health officials and others concerned with appropriate actions to take at hazardous waste sites may want information on levels of exposure associated with more subtle effects in humans or animals (LOAEL) or exposure levels below which no adverse effects (NOAELs) have been observed. (cdc.gov)
  • An MRL is defined as an estimate of daily human exposure to a substance that is likely to be without an appreciable risk of adverse effects (noncarcinogenic) over a specified duration of exposure. (cdc.gov)
  • The pre-WPI could effectively protect the stability of anthocyanins, and the effect was better than that of the natural whey protein isolate (NW). (bvsalud.org)
  • Protein protects anthocyanins from degradation, and this protective effect is influenced by the preheating temperature of protein and the structure of protein. (bvsalud.org)
  • Yamaoka K, Ohno S, Kawasaki H, Suzuki K. Overexpression of a beta-galactoside binding protein causes transformation of BALB3T3 fibroblast cells. (arjournals.org)
  • Together, we successfully identified three major substances in purified FFC of finger citron and determined the excellent antiaging activity of FFC, which is attributed to its strong antioxidative activity and effect on homeostasis of ROS. (frontiersin.org)
  • The aim of the study was to clarify antioxidative effects of bilberry and chokeberry fruits alone and with addition of a LAB-strain, Lactobacillus plantarum HEAL19, in an I/R-model in mice. (biomedcentral.com)
  • Abstract Galectins, highly conserved β-galactoside-binding lectins, have diverse regulatory roles in development and immune homeostasis and can mediate protective functions during microbial infection. (nsf.gov)
  • this effect, associated with its fermentation by the local microbial flora, gives rise to the typical symptoms of lactose intolerance. (researchgate.net)
  • Polyphenols have received considerable attention for their promotive effects on colonic health. (bvsalud.org)
  • QR is a potent immunomodulatory molecule due to its direct modulatory effects on several immune cells, cytokines, and other immune molecules. (c19early.org)
  • Many research studies have highlighted the positive effects of natural flavonoids on chronic diseases, including PCa. (mdpi.com)
  • A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen. (ac.ir)
  • 18) have reported the protective action of an adzuki extract against acetaminophen-induced hepatotoxicity via a hepatic γ-glutamylcysteinylglycine-mediated antioxidation/detoxification system in rat liver after four weeks of feeding. (healthjade.com)
  • Serious' effects are those that evoke failure in a biological system and can lead to morbidity or mortality (e.g., acute respiratory distress or death). (cdc.gov)
  • Pharmacological effects and pharmacokinetic properties of icariin, the major bioactive component in Herba Epimedii. (cosmeticsandtoiletries.com)
  • In this study, we aimed to evaluate the effect of salidroside on the activities of the different drug-metabolizing enzymes CYP1A2, CYP2B6, CYP2C9, CYP2D6 and CYP3A4 in rats, in which a specific probe drug was used for each enzyme. (ac.ir)
  • effect of evodiamine on CYP enzymes in rats by a cocktail method. (ac.ir)
  • Effects of aescin on cytochrome P450 enzymes in rats. (ac.ir)
  • Les interactions sucres/protéines (enzymes, lectines) sont au cœur de la communication cellulaire tant extracellulaire (interactions cellule-cellule, cellule-matrice, hôte-pathogène) qu'intracellulaire (GlcNAcylation en tant que modification post-traductionnelle). (univ-nantes.fr)
  • In UVB-irradiated human fibroblast cells, gallic acid glucoside lowered matrix metalloproteinase-1 levels and increased the collagen content, which was indicative of a stronger anti-aging effect than that of gallic acid or arbutin. (springeropen.com)
  • ATSDR acknowledges that a considerable amount of judgment may be required in establishing whether an end point should be classified as a NOAEL, 'less serious' LOAEL, or 'serious' LOAEL, and that in some cases, there will be insufficient data to decide whether the effect is indicative of significant dysfunction. (cdc.gov)
  • Our data showed that salidroside exhibited an inductive effect on CYP1A2, CYP2B6, CYP2C9 and CYP3A4 activities by changing the main pharmacokinetic parameters (t1/2, CL/F, Cmax and AUC(0-∞)) of the four probe drugs in rats. (ac.ir)
  • MRLs are derived when reliable and sufficient data exist to identify the target organ(s) of effect or the most sensitive health effect(s) for a specific duration within a given route of exposure. (cdc.gov)
  • As these kinds of health effects data become available and methods to assess levels of significant human exposure improve, these MRLs will be revised. (cdc.gov)
  • In vivo , the purified FFC significantly increased the mean and maximum lifespan of Caenorhabditis elegans by 31.26 and 26.59%, respectively, and showed no side effects on their physiological functions. (frontiersin.org)
  • 7. Wu Q, Zhang Q, Wen C, Hu L, Wang X, and Lin G. The effect of MS-275 on CYP450 isoforms activity in rats by cocktail method. (ac.ir)
  • Effects of hydroxysafflor yellow A on the activity and mRNA expression of four CYP isozymes in rats. (ac.ir)
  • The adzuki bean paste showed potential hypoglycemic activity in both normal mice and streptozotocin (STZ)-induced diabetic rats after an oral administration of sucrose, but did not show any effect on the blood glucose concentration after glucose administration, suggesting that the active fraction suppressed the postprandial blood glucose level by inhibiting alpha-glucosidase and alpha-amylase, irrespective of the endogenous blood insulin level. (healthjade.com)
  • As an example, acute inhalation MRLs may not be protective for health effects that are delayed in development or are acquired following repeated acute insults, such as hypersensitivity reactions, asthma, or chronic bronchitis. (cdc.gov)
  • author = {Matthieu Sawaf and Hélène Dumortier and Fanny Monneaux}, doi = {10.1155/2016/5767106}, issn = {2314-7156}, year = {2016}, date = {2016-01-01}, journal = {Journal of Immunology Research}, volume = {2016}, pages = {5767106}, abstract = {Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by B cell hyperactivity leading to the production of autoantibodies, some of which having a deleterious effect. (cnrs.fr)
  • Exercise, in particular, has been shown to have a powerful effect on mitochondrial biogenesis, as it increases the demand for energy in the muscles and stimulates the production of new mitochondria to meet this demand. (bioactor.com)
  • 3. HEALTH EFFECTS considered to be important because it helps the users of the profiles to identify levels of exposure at which major health effects start to appear. (cdc.gov)
  • LOAELs or NOAELs should also help in determining whether or not the effects vary with dose and/or duration, and place into perspective the possible significance of these effects to human health. (cdc.gov)
  • MRLs are based on noncancerous health effects only and do not consider carcinogenic effects. (cdc.gov)
  • In the present study, we examined the memory-improving effects of the extracts of C. chinensis and C. campestris on scopolamine (SCOP)-induced memory deficit and explored their underlying mechanism in mice. (mdpi.com)
  • This study was focused on developing a pearl pigment which might have a similar sparkling effect as snow. (scsk.or.kr)
  • Additionally, molecular dynamics simulations were performed to estimate stability and flexibility of best complexes, while collagenase activity colorimetric assay was carried out to study the effects of (1), (2) and (3) on collagenase. (ijpsonline.com)
  • This effect was found to be due to its structure and purity, and this concept was also applied to development of our pearl pigments. (scsk.or.kr)
  • Fluorescence studies indicated that pre-WPI there existed a solid binding affinity and static quenching for malvidin-3-galactoside (M3G). (bvsalud.org)
  • The points in the figures showing no-observed-adverse-effect levels (NOAELs) or lowest-observed-adverse-effect levels (LOAELs) reflect the actual doses (levels of exposure) used in the studies. (cdc.gov)
  • Despite causing unpleasant side effects in some people, soluble fibers in soybeans are generally considered healthy. (healthline.com)
  • Due to high rainfall, irrigation practices and/or poor soil drainage, waterlogging annually affects large areas of farmlands worldwide, and these effects result in anoxic (absence of O 2 ) soils and severe hypoxia or anoxia within crop roots. (biomedcentral.com)
  • the most widely used pearl effect pigment is the mica-based pigment, which uses natural mica as the substrate that is in turn coated with metal oxide interference layer. (scsk.or.kr)
  • More specifically, this invented pearl effect pigments are the mixture of glass-flake and glass-flake coated metal oxides and present the optical properties of snow matrix such as refractive index and particle size, unlike only the glass-flake or glass-flake coated metal oxides to be applied in. (scsk.or.kr)
  • Using base material having similar physical properties (refractive index and particle size) as snow matrix as platelet for pearl effect pigments, these invented pigments present a three-dimensional glittering effect of the snow matrix. (scsk.or.kr)
  • The skin-whitening and anti-aging effects exerted by matrix metalloproteinase-1 (MMP-1) and collagen content were determined as well. (springeropen.com)
  • Tinospora cordifolia is an important ayurvedic herb known for its immune stimulating effect. (arjournals.org)
  • One of the repressive effect of CD33 on monocyte activation requires phosphoinositide 3-kinase/PI3K. (cusabio.com)
  • The inhibitory effect of T2CA on phopho-galectin-3 expression and the activation of T-cytotoxic and NK cells suggested its protective effects against pathogenic infections and human malignancies via its immune stimulating mechanisms. (arjournals.org)