Proteasome inhibitors. Medical search. Frequent questions

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Anatomy20

Cell Line, Tumor Cell Line Tumor Cells, Cultured Endoplasmic Reticulum HeLa Cells Cells, Cultured Cell Nucleus COS Cells HEK293 Cells Cytosol Fibroblasts Jurkat Cells Mitochondria Inclusion Bodies K562 Cells Cell Line, Transformed HCT116 Cells Cytoplasm Lysosomes HL-60 Cells

Organisms4

Thermoplasma Saccharomyces cerevisiae Mice, Nude Cercopithecus aethiops

Diseases4

Multiple Myeloma Neoplasms Lymphoma, Mantle-Cell Hyalinosis, Systemic

Chemicals and Drugs97

Proteasome Inhibitors Proteasome Endopeptidase Complex Leupeptins Boronic Acids Pyrazines Cysteine Proteinase Inhibitors Cysteine Endopeptidases Multienzyme Complexes Protease Inhibitors Acetylcysteine Ubiquitins Ubiquitin Oligopeptides Lactones Antineoplastic Agents Ubiquitinated Proteins NF-kappa B Peptide Hydrolases Polyubiquitin Ubiquitin-Protein Ligases Enzyme Inhibitors Chymotrypsin Thiostrepton Caspases I-kappa B Proteins Protein Subunits Proto-Oncogene Proteins c-bcl-2 RNA, Small Interfering RNA, Messenger Clioquinol Ubiquitin-Conjugating Enzymes Ubiquitin-Activating Enzymes Myeloid Cell Leukemia Sequence 1 Protein Calpain Caspase 3 Protein Synthesis Inhibitors Pyrroles Proteins Endopeptidases Butanes Dipeptides Cyclin-Dependent Kinase Inhibitor p27 Tumor Suppressor Protein p53 DNA-Binding Proteins Apoptosis Regulatory Proteins Lactams, Macrocyclic Cell Cycle Proteins Benzoquinones TNF-Related Apoptosis-Inducing Ligand Molecular Chaperones Adenosine Triphosphatases HSP90 Heat-Shock Proteins Transcription Factors Neoplasm Proteins Carrier Proteins Thiocarbamates Nuclear Proteins Membrane Proteins bcl-2-Associated X Protein Histone Deacetylase Inhibitors HSP70 Heat-Shock Proteins Activating Transcription Factor 4 Caspase Inhibitors Cycloheximide Cyclin-Dependent Kinase Inhibitor p21 Reactive Oxygen Species Hydroxamic Acids Glutathione Synthase HSP72 Heat-Shock Proteins Recombinant Proteins Transcription Factor CHOP Intracellular Signaling Peptides and Proteins Hydroxyquinolines Proto-Oncogene Proteins c-mdm2 Recombinant Fusion Proteins Sulfones Ligases Tumor Necrosis Factor-alpha Microtubule-Associated Proteins Amino Acid Chloromethyl Ketones Caspase 8 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt Proto-Oncogene Proteins Protein-Serine-Threonine Kinases Ubiquitin-Protein Ligase Complexes Saccharomyces cerevisiae Proteins Tumor Suppressor Proteins Boron Compounds Heat-Shock Proteins Peptides Phthalimides SKP Cullin F-Box Protein Ligases X-Linked Inhibitor of Apoptosis Protein S-Phase Kinase-Associated Proteins Semicarbazones Cullin Proteins Muscle Proteins

Analytical, Diagnostic and Therapeutic Techniques and Equipment13

Blotting, Western Transfection Immunoblotting Xenograft Model Antitumor Assays Drug Screening Assays, Antitumor Models, Biological Immunoprecipitation Reverse Transcriptase Polymerase Chain Reaction Inhibitory Concentration 50 Flow Cytometry Drug Evaluation, Preclinical Microscopy, Fluorescence Antineoplastic Combined Chemotherapy Protocols

Phenomena and Processes37

Apoptosis Ubiquitination Proteolysis Drug Synergism Down-Regulation Protein Processing, Post-Translational Drug Resistance, Neoplasm Signal Transduction Cell Survival Transfection Dose-Response Relationship, Drug Protein Binding Enzyme Activation Phosphorylation Amino Acid Sequence Cell Death Mutation Protein Transport Cell Cycle Protein Stability Autophagy Time Factors Cell Proliferation Hydrolysis Unfolded Protein Response Up-Regulation Gene Expression Regulation RNA Interference Transcription, Genetic Protein Structure, Tertiary Oxidative Stress Inhibitory Concentration 50 Endoplasmic Reticulum-Associated Degradation Endoplasmic Reticulum Stress Protein Folding Protein Biosynthesis Substrate Specificity

Information Science2

Molecular Sequence Data Amino Acid Sequence

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Information Science

Proteasome Inhibitors Proteasome Endopeptidase Complex Leupeptins Boronic Acids Pyrazines Cysteine Proteinase Inhibitors Cysteine Endopeptidases Multienzyme Complexes Protease Inhibitors Acetylcysteine Ubiquitins Ubiquitin Apoptosis Oligopeptides Ubiquitination Cell Line, Tumor Lactones Antineoplastic Agents Multiple Myeloma Proteolysis Ubiquitinated Proteins NF-kappa B Cell Line Peptide Hydrolases Polyubiquitin Drug Synergism Ubiquitin-Protein Ligases Blotting, Western Enzyme Inhibitors Down-Regulation Chymotrypsin Thiostrepton Tumor Cells, Cultured Caspases I-kappa B Proteins Protein Processing, Post-Translational Endoplasmic Reticulum Drug Resistance, Neoplasm Protein Subunits HeLa Cells Signal Transduction Cells, Cultured Cell Survival Transfection Dose-Response Relationship, Drug Proto-Oncogene Proteins c-bcl-2 Protein Binding Enzyme Activation Immunoblotting RNA, Small Interfering Phosphorylation Molecular Sequence Data RNA, Messenger Clioquinol Amino Acid Sequence Ubiquitin-Conjugating Enzymes Ubiquitin-Activating Enzymes Myeloid Cell Leukemia Sequence 1 Protein Cell Death Calpain Mutation Protein Transport Cell Cycle Caspase 3 Protein Synthesis Inhibitors Xenograft Model Antitumor Assays Protein Stability Pyrroles Proteins Endopeptidases Butanes Autophagy Time Factors Dipeptides Cyclin-Dependent Kinase Inhibitor p27 Tumor Suppressor Protein p53 DNA-Binding Proteins Cell Proliferation Apoptosis Regulatory Proteins Lactams, Macrocyclic Cell Cycle Proteins Cell Nucleus COS Cells Hydrolysis Drug Screening Assays, Antitumor Benzoquinones Unfolded Protein Response Up-Regulation Models, Biological Gene Expression Regulation HEK293 Cells Immunoprecipitation TNF-Related Apoptosis-Inducing Ligand Reverse Transcriptase Polymerase Chain Reaction Molecular Chaperones Adenosine Triphosphatases HSP90 Heat-Shock Proteins Transcription Factors Neoplasm Proteins RNA Interference

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