• No evidence of tumor was identified in adnexa, uterus or omentum in microscopy, but only GCT metastasis was detected in Douglas space peritoneal nodules. (researchsquare.com)
  • 2 - 4 Additionally, there are rare reports of primary tumors outside the abdominal cavity with metastasis to the umbilicus, including breast, lung and penis. (aafp.org)
  • Metastasis to the pelvic peritoneum or omentum, independent of uterine myometrial invasion and lung metastases, is extremely rare in invasive mole. (biomedcentral.com)
  • We depicted a single-cell landscape of OC ecosystem with five tumour-relevant sites: peripheral blood (PB), pelvic lymph node (PLN), primary tumour (Pri.OT), omentum metastasis (Met.Ome), and malignant ascites. (mendeley.com)
  • The functional effects of GRO and TAK1/NFkB signaling cascade in omental metastasis will be further investigated on primary ovarian cancer cells isolated from ovaries and omenta, as well as using ex vivo and in vivo tumorigenic models. (hku.hk)
  • Indeed, while it is clear that cancer metastasis must involve detachment of cancer cells from the primary tumor, such a phenomenon could well be attributed to mutation(s) and/or aberrant gene expression patterns in one or a few genes and not necessarily reflect involvement of a more coordinated process such as EMT [ 9 ]. (biomedcentral.com)
  • Ovarian cancer metastasis is primarily due to the exfoliation of malignant cells or cell aggregates from the primary tumor into the abdominal cavity and their subsequent spread and attachment to visceral and parietal peritoneal surfaces of abdominal organs such as the omentum. (biomedcentral.com)
  • Most sources include the following three: Gastrophrenic ligament-extends to the underside of the left dome of the diaphragm Gastrocolic ligament-extends to the transverse colon (occasionally on its own considered synonymous with "greater omentum") Gastrosplenic ligament (or Gastrolienal) ligament)- extends to the spleen, overlying the kidney The splenorenal ligament (or lienorenal ligament) (from the left kidney to the spleen) is occasionally considered part of the greater omentum. (wikipedia.org)
  • The dorsal leaf of the omentum is freed up from its short epiploic vessels and from a few vascular attachments to the spleen and pancreas. (vin.com)
  • By the time the surgery was finished, I lost two, four-inch sections of my intestines, my omentum, my spleen and half of the lining of my diaphragm - and that was only 70% if the cancer. (curetoday.com)
  • The transverse colon is related anterosuperiorly to the liver, gallbladder, stomach, greater omentum and spleen. (learnsurgeryonline.com)
  • The lower pole of the spleen and the greater curvature of the stomach with greater omentum attached lie superior to the splenic flexure. (learnsurgeryonline.com)
  • GAS has a much poorer prognosis than HPV-associated cervical adenocarcinoma, with propensity for presentation at advanced stage and wide dissemination to unusual sites such as the ovary, omentum and peritoneum. (nih.gov)
  • 1 Indeed, the primary tumor in most cases of Sister Joseph's nodule is intra-abdominal: stomach, large and small intestine, pancreas, kidney, uterus, ovary or gallbladder. (aafp.org)
  • Gene expression profiling (Affymetrix, U133) was carried out on 14 matched sets of primary (ovary) and metastatic (omentum) ovarian cancer (serous adenocarcinoma) patient samples. (biomedcentral.com)
  • Fertility-sparing surgery will be performed in certain cases, the procedure should include a detailed inspection of the contralateral ovary and also negative for malignancy omentum and ovary biopsy. (bvsalud.org)
  • The greater omentum develops from the dorsal mesentery that connects the stomach to the posterior abdominal wall. (wikipedia.org)
  • Consequently, the blind-ended sac (also called the lesser sac) formed by the dorsal mesentery is brought inferiorly, where it assumes its final position as the greater omentum. (wikipedia.org)
  • Exploration of his abdomen revealed multiple firm gooseberry-like nodules of different sizes involving the greater omentum, peritoneal cavity and the mesentery. (biomedcentral.com)
  • Here we present an unusual case of EGIST that presented with multiple gooseberry-like nodules involving the whole abdominal cavity, the omentum, peritoneum and small bowel mesentery, which makes a radical resection difficult. (biomedcentral.com)
  • Exploration revealed multiple firm gooseberry-like nodules of different sizes ranging between 1 and 5cm in diameter (Figures 4 , 5 , 6 and 7 ), involving the greater omentum, peritoneal cavity and the mesentery, but liver texture was normal. (biomedcentral.com)
  • The main bulk of the tumour was excised together with the greater omentum and part of the mesentery, however, residual tumour remained stuck to the small bowel and great vessels. (biomedcentral.com)
  • The primary laparotomy revealed a 8 x7 x6cm, solid mass arising from distal ileum, separated from the right adnexa, and adherent to the adjacent mesentery and small intestine, resulting in intestinal stricture. (researchsquare.com)
  • 63cm small intestine with mesentery and the mass was resected merely in toto , and primary ileal mesenchymal tumor with whole intestinal layer invasion was suggested by the intraoperative frozen section. (researchsquare.com)
  • Although primary neoplasms arising in the mesentery are rare, the mesentery is a major avenue for the dissemination of tumours, which can spread through hematogenous, lymphatic, direct or peritoneal seeding. (sajr.org.za)
  • Secondary involvement of the mesentery from tumours elsewhere is much more common than primary mesenteric neoplasms such as desmoid tumour, inflammatory myofibroblastic tumour (IMFT), and others. (sajr.org.za)
  • They appear as solitary or multiple irregular hypoechoic masses with heterogeneous echotexture and increased echogenicity in the surrounding mesentery and omentum on USG and show increased internal vascularity on colour Doppler. (sajr.org.za)
  • Desmoplastic small round-cell tumors (DSRCT) frequently develop in the retroperitoneum, pelvis, omentum, and mesentery. (bvsalud.org)
  • The uterus, adnexa, omentum and peritoneum appeared grossly normal. (researchsquare.com)
  • Staging fallopian tube cancer involves the removal of both fallopian tubes and of the ovaries, uterus, cervix, infracolic omentum, and retroperitoneal lymph nodes, in addition to peritoneal washings and peritoneal biopsies. (medscape.com)
  • To claim the diagnosis of a primary EESS, the uterus must be free of tumor as it constitutes the main primary site of ESS [ 2 ]. (biomedcentral.com)
  • Primary Peritoneal Mesothelioma is a rapidly aggressive and rare neoplasm that arises from the lining of mesothelial cells of the peritoneum and spreads extensively within the confines of the abdominal cavity. (karger.com)
  • The patient underwent hysteroscopy and laparoscopy, by which an iatrogenic uterine perforation and omentum and pelvic peritoneum metastases were confirmed. (biomedcentral.com)
  • Peritoneal neoplasia can originate de novo from the peritoneal tissues (primary) or invade or metastasize into the peritoneum from adjacent or remote organs (secondary). (medscape.com)
  • Surgical exploration helped find a sarcoma of the great omentum and treat the disease. (iomcworld.org)
  • The patient had no history of breast cancer, and mammography showed no evidence of breast carcinoma as a primary site for her metastatic disease. (aafp.org)
  • Fresh samples including primary ovarian tumour, omentum metastatic tumour, pelvic lymph node, malignant ascites and peripheral blood were obtained from these patients during surgery. (mendeley.com)
  • One model that has gained credibility in recent years is that metastasizing cells at least partially recapitulate the developmental process of epithelial-to-mesenchymal transition (EMT) in their transit from primary to metastatic sites. (biomedcentral.com)
  • While histological examination reveled no morphological distinction between the matched sets of primary and metastatic samples, gene expression profiling clearly distinguished two classes of metastatic samples. (biomedcentral.com)
  • Further analyses focusing on genes previously associated with EMT clearly distinguished the primary from metastatic samples in all but one patient. (biomedcentral.com)
  • Our results are consistent with a role of EMT in most if not all ovarian cancer metastases and demonstrate that identical morphologies between primary and metastatic cancer samples is insufficient evidence to negate a role of EMT in the metastatic process. (biomedcentral.com)
  • This mechanism of intra-abdominal metastatic spread allows for the capture and molecular comparison of primary and metastatic cancer cells isolated from the same patient, providing a favorable opportunity to evaluate the potential role of epithelial-to-mesenchymal transition (EMT) in the metastatic process. (biomedcentral.com)
  • Computed tomography (CT) of the chest, abdomen and pelvis ( Figure 2 ) showed diffuse caking of the omentum with tumor metastases and extension of the tumor into the periumbilical region. (aafp.org)
  • No primary tumor was ever identified. (aafp.org)
  • 2 In an estimated 9 to 17 percent of cases, the primary tumor is never found. (aafp.org)
  • Osteosarcoma is the most common primary malignant tumor of bone tumor, although there are a lot of therapies such as surgery, radiotherapy and chemotherapy, its prognosis is still very poor. (qxmd.com)
  • Primary peritoneal carcinoma is treated with tumor debulking followed by chemotherapy with 5-fluorouracil, doxorubicin, or cisplatin. (medscape.com)
  • How long after the primary tumour was removed (you don't say where it was) were you treated for omentum cancer? (cancer.org)
  • Other described primary peritoneal cancers and tumors include malignant mesothelioma, benign papillary mesothelioma, desmoplastic small round cell tumors, peritoneal angiosarcoma, leiomyomatosis peritonealis disseminata (LPD), and peritoneal hemangiomatosis. (medscape.com)
  • The primary outcome measure was the TBR, which was obtained by normalizing to the omentum (in 106 lesions) or other solid organs (27 lesions). (cancernetwork.com)
  • A fold of this tissue called the omentum covers and connects the organs in the abdomen. (cancer.net)
  • The greater omentum is larger than the lesser omentum, which hangs down from the liver to the lesser curvature. (wikipedia.org)
  • Here, we present an unusual case of primary DSRCT in the liver. (bvsalud.org)
  • Ovaries are the primary source of estrogen and progesterone for the body. (cancer.net)
  • Primary peritoneal cancers, some of which have been implicated in many cases of carcinomas of unknown primary origin, include ovarian cancer arising in women several years after bilateral oophorectomy. (medscape.com)
  • However, the underlying molecular mechanism of how omentum modulating ovarian cancer colonization remains unclear. (hku.hk)
  • Our previous studies have found that TAK1/NFkB signalling cascade is required for ovarian cancer cell aggressiveness and could be activated by omentum conditioned medium (OCM)1, suggesting that there are some factors in OCM playing activators for this pathway. (hku.hk)
  • These pilot data suggest that Gro-α secreted from omentum plays as a key chemokine in activating TAK1/NFkB pathway in ovarian cancer cells. (hku.hk)
  • Given the patient's age, a malignancy was the primary concern. (aafp.org)
  • c - e An iatrogenic uterine perforation (arrow) ( c ) and the lesions [right uterosacral ligament ( d ) and omentum ( e )] of mole under laparoscopy. (biomedcentral.com)
  • The primary extra-uterine location of ESS is an extremely uncommon occurrence. (biomedcentral.com)
  • The histopathological examination of the resected specimens disclosed the diagnosis of primary extra-uterine ESS arising from ovarian endometriosis. (biomedcentral.com)
  • A cranial ventral abdominal midline incision can be used to gain access to the omentum and its attachments in order to create a pedicle. (vin.com)
  • Factors that predispose a patient to torsion include anatomic variations of the omentum itself, such as accessory omentum, bifid omentum, irregular accumulations of omental fat (in patients who are obese), and narrowed omentum pedicle. (medscape.com)
  • Multiple Primaries (Pre-2007)--Thyroid: Does the rule in the 3rd Edition of the SEER Program Code Manual apply to cases diagnosed before 1998 that states if there are two separate carcinomas in the thyroid, one papillary and the other follicular, it is one primary and coded to the combination code 8340/3 [Papillary and follicular carcinoma]? (cancer.gov)
  • The common anatomical term "epiploic" derives from "epiploon", from the Greek epipleein, meaning to float or sail on, since the greater omentum appears to float on the surface of the intestines. (wikipedia.org)
  • The greater omentum is the larger of the two peritoneal folds. (wikipedia.org)
  • The two layers of the greater omentum descend from the greater curvature of the stomach and the beginning of the duodenum. (wikipedia.org)
  • The greater omentum is usually thin, and has a perforated appearance. (wikipedia.org)
  • The greater omentum is often defined to encompass a variety of structures. (wikipedia.org)
  • The phrenicosplenic ligament is part of the greater omentum. (wikipedia.org)
  • The right and left gastroepiploic arteries (also known as gastroomental) provide the sole blood supply to the greater omentum. (wikipedia.org)
  • The right and left gastroepiploic arteries anastomose within the two layers of the anterior greater omentum along the greater curvature of the stomach. (wikipedia.org)
  • The greater omentum varies in size and texture between animals. (vin.com)
  • The higher incidence of torsion on the right side of the omentum is related to the greater size and mobility of that side. (medscape.com)
  • Cremonini C, Bertolucci A, Tartaglia D, Menonna F, Galatioto C, Chiarugi M. Acute abdomen caused by greater omentum torsion: A case report and review of the literature. (medscape.com)
  • The recommended standardized treatment includes primary surgery for diagnosis, staging and cytoreduction, followed by adjuvant chemotherapy Surgery must be performed by an Oncologist Gynecologist or an Oncologist Surgeon because inadequate surgery performed by another specialist has been reported in 75% of cases. (bvsalud.org)
  • The research suggests that some forms of peritoneal cancer, such as extraovarian primary peritoneal carcinoma (EOPPC), affect only females. (medicalnewstoday.com)
  • Primary peritoneal carcinoma usually manifests with abdominal distention and diffuse nonspecific abdominal pain secondary to ascites. (medscape.com)
  • If all causes of impaired wound healing are eliminated but the wound continues to not heal, then a flap of omentum can be mobilized and moved to the site of the wound in an attempt to provide new arterial, venous, and lymphatic communications. (vin.com)
  • As the torsion progresses, arterial occlusion leads to acute hemorrhagic infarction, and necrosis of the omentum eventually occurs. (medscape.com)
  • A break of a contained hematoma is usually involved in splenic rupture, which occurs almost exclusively during acute infection and the primary attack ( 6 ). (cdc.gov)
  • Although uncommon, GAS is likely to increase in relative prevalence with the introduction of HPV vaccination and precursor lesions will not be detected by primary HPV-based screening programs. (nih.gov)
  • Venous return is compromised, and the distal omentum becomes congested and edematous. (medscape.com)
  • Omentum below that point is edematous and congested. (medscape.com)
  • The omental lengthening procedures described by Ross and Pardo in the dog gave new impetus for further exploration into the extraabdominal uses of omentum. (vin.com)
  • In omental torsion, the omentum twists around a pivotal point, usually in a clockwise direction (see the image below). (medscape.com)
  • Chen F, Liu J, Fan F, Xu W, Lv Z. Primary omental torsion in children: single-center experience of 17 cases. (medscape.com)
  • Torsion of the omentum may be either primary or secondary. (medscape.com)
  • There are two main types of peritoneal cancer: primary and secondary. (medicalnewstoday.com)
  • As the review also explains, staging for peritoneal cancer works differently in primary and secondary cases. (medicalnewstoday.com)
  • Since the early 1900s, omentum has been used in a variety of surgical situations most notably in gastrointestinal and urogenital operations in people. (vin.com)
  • The omentum participates directly in bacterial and foreign material absorption and in the transport of phagocytes into the peritoneal cavity. (vin.com)
  • This category will also be used in primary coding to classify bacterial infections of unspecified nature or site. (cdc.gov)
  • When I first presented with my primary colon cancer in April of 2008, my CEA levels were 0.2 to 0.3. (livejournal.com)
  • Further, we identified two endothelial subsets in primary tumours and one MAIT cluster in ascites predicting the responses to platinum-based chemotherapy of OC patients. (mendeley.com)
  • The twisted portion of the omentum tends to be localized to a right-side segment, thereby giving rise to the sudden onset of pain and signs of peritoneal irritation on the right side of the abdomen. (medscape.com)
  • In primary torsion, a mobile segment of omentum rotates around a proximal fixed point in the absence of any associated intra-abdominal pathology. (medscape.com)
  • Primary abscess of the omentum: report of a case. (bmj.com)
  • Accordingly, the chemotherapy used to treat primary fallopian tube cancers is based on the standard management of ovarian cancers. (medscape.com)
  • Standardized treatment includes primary surgery with the objective to perform an optimal cytoreduction followed by chemotherapy Treatment must be individualized according to each patient. (bvsalud.org)