Praziquantel albendazole. Medical search. Frequent questions

In cases of lymphatic filariasis (elephantiasis) caused by Wuchereria bancrofti or Brugia malayi, albendazole is sometimes given as an adjunct to ivermectin or diethylcarbamazine in order to suppress microfilaremia. (wikipedia.org)
Albendazole has a similar effectiveness to ivermectin in these cases, though it needs to be given for 21 days rather than the 2 days needed for ivermectin. (wikipedia.org)
Patient with failure of albendazole and ivermectin treatment. (cdc.gov)
We describe a protocol for a trial investigating the efficacy and safety of the co-administration of ivermectin and albendazole against trichuriasis. (biomedcentral.com)
A double-blind, placebo-controlled randomized controlled trial will be conducted in three countries (Côte d'Ivoire, Tanzania and Lao PDR) with the aim to determine the efficacy, safety and extended effects of co-administered ivermectin and albendazole compared to standard albendazole monotherapy. (biomedcentral.com)
This trial will provide robust results on the efficacy and safety of co-administration of ivermectin and albendazole with the aim to better inform WHO recommendations on control of STHs. (biomedcentral.com)
These youngsters were living in a community, which was meant to receive an integrated mass drug administration (MDA) of ivermectin, albendazole, Zithromax, and praziquantel. (cdc.gov)
Albendazole jẹ anthelmintic sintetiki, eyiti o jẹ ti ẹgbẹ ti awọn itọsẹ benzimidazole pẹlu iṣẹ ṣiṣe lodi si ọpọlọpọ awọn kokoro ati ni ipele iwọn lilo ti o ga julọ tun lodi si awọn ipele agbalagba ti fluke ẹdọ.ivermectin jẹ ti ẹgbẹ ti avermectins ati pe o ṣe lodi si awọn kokoro ati awọn parasites. (joycomevet.com)
Albendazole ati ivermectin jẹ oogun de-worming ti o gbooro, ayafi fun itọju hookworm, roundworm, whipworm, pinworm, ati nematode trichinella spiralis miiran le ṣee lo fun itọju cysticercosis ati echinococcosis. (joycomevet.com)
Using a delivery strategy known as mass drug administration (MDA), the program gives preventive medications (albendazole or mebendazole, ivermectin, praziquantel, azithromycin, and tetracycline) alone or in a package (depending on disease prevalence) to every eligible child and adult residing in each disease-endemic district in beneficiary countries. (endinafrica.org)
Iverfull - albendazole, ivermectin,praziquantel 6 Tbs. (petmedsmex.com)
For the helminths, ivermectin can be a great choice (good for the Lyme too), praziquantel and albendazole are ones I use. (drnicoladucharme.com)

Albendazole is an effective treatment for: Flatworms Fasciolosis Cestodes (tapeworms), as an alternative to praziquantel or niclosamide for adult beef tapewormss and as an alternative to praziquantel for pork tapeworms. (wikipedia.org)
Your pediatrician may prescribe oral drugs such as praziquantel or, as an alternative, niclosamide to treat a tapeworm infestation. (healthychildren.org)
Three potential drugs-niclosamide, praziquantel, and albendazole-have been considered for use for preventive chemotherapy in Taenia solium taeniasis control programs through mass drug administration or targeted chemotherapy. (paho.org)
In this Guideline, we provide recommendations for preventive chemotherapy in Taenia solium -endemic areas using niclosamide, praziquantel, or albendazole, including at which dose and in which population groups. (paho.org)
a single dose of Niclosamide or Praziquantel or Albendazole is enough. (zoonotic-diseases.org)

Preventive chemotherapy, using the benzimidazoles (albendazole and mebendazole) is the current main recommended control strategy. (biomedcentral.com)
Albendazole and mebendazole in the treatment of ancylostomiasis in school children between the ages of 6-15 in Swat, Pakistan. (jptcp.com)

Though praziquantel is often better at treating tapeworm infections, albendazole is used more often in endemic countries due to being cheaper and having a broader spectrum. (wikipedia.org)
Albendazole is used for treating certain tapeworm infections. (amdprojects.de)

The mean apparent terminal elimination half-life of albendazole sulfoxide typically ranges from 8 to 12 hours in 25 normal subjects, as well as in 14 hydatid and 8 neurocysticercosis patients. (nih.gov)
Mean T max and mean plasma elimination half-life of albendazole sulfoxide were unchanged. (medlibrary.org)

Antiparasitic drugs in neurocysticercosis: albendazole or praziquantel? (nih.gov)
Other antiparasitic drugs, including albendazole and praziquantel, are available specifically for treating cysticercosis. (healthychildren.org)
ALBENDAZOLE is an antiparasitic. (fr.nf)
Assessment of combined antiparasitic drugs praziquantel and albendazole versus albendazole alone in the treatment of active parenchymal neurocysticercosis in Tanzania and Zambia. (who.int)

Cysticercosis (especially neurocysticercosis), which is caused by the larval form of the pork tapeworm (i.e. albendazole is the drug of choice for larval pork tapeworms, but not adult pork tapeworms). (wikipedia.org)
The drugs praziquantel and albendazole are used to treat cysticercosis, but it is not clear if these drugs are effective in all patients, such as those with calcified cysts or brain enlargement. (nih.gov)
Do not use it if you had an allergic reaction to praziquantel, or if you have a tapeworm infection in your eye (ocular cysticercosis). (optionrx.com)

Plasma concentrations of albendazole sulfoxide increase in a dose-proportional manner over the therapeutic dose range following ingestion of a fatty meal (fat content 43.1 g). (nih.gov)
Urinary excretion of albendazole sulfoxide is a minor elimination pathway with less than 1% of the dose recovered in the urine. (nih.gov)
Following single-dose administration of 200 mg to 300 mg (approximately 10 mg/kg) albendazole to 3 fasted and 2 fed pediatric patients with hydatid cyst disease (age range 6 to 13 years), albendazole sulfoxide pharmacokinetics were similar to those observed in fed adults. (nih.gov)
Nematodes Ascariasis, which can be cured with a single dose of albendazole. (wikipedia.org)
A single dose of albendazole is sufficient to treat intestinal infestations by A. duodenale or Necator americanus. (wikipedia.org)
Only a single dose of albendazole is needed. (wikipedia.org)
for this condition is a single dose of praziquantel , repeated in 10 days. (nih.gov)
Dexamethasone: Steady-state trough concentrations of albendazole sulfoxide were about 56% higher when dexamethasone was coadministered with each dose of albendazole. (nih.gov)
standard (biannual single-dose albendazole and a yearly single-dose praziquantel) 2. (mak.ac.ug)
intensive (quarterly triple-dose albendazole [daily, three days] and quarterly single-dose praziquantel) treatment arms. (mak.ac.ug)
Steady-state trough concentrations of albendazole sulfoxide were about 56% higher when 8 mg dexamethasone was co-administered with each dose of albendazole (15 mg/kg/day) in 8 neurocysticercosis patients. (medlibrary.org)
Following a single dose of albendazole (400 mg), the pharmacokinetics of theophylline (aminophylline 5.8 mg/kg infused over 20 minutes) were unchanged. (medlibrary.org)
However, available human data from a small number of published case series and reports on the use of multiple-dose albendazole in the 1 st trimester of pregnancy, and several published studies on single-dose albendazole use later in pregnancy, have not identified any drug-associated risks for major birth defects, miscarriage, or adverse maternal or fetal outcomes. (medlibrary.org)
In animal reproductive studies, oral administration of albendazole during the period of organogenesis caused embryotoxicity and skeletal malformations in pregnant rats (at doses of 0.10 times and 0.32 times the maximum recommended human dose based on body surface area in mg/m 2 ) and pregnant rabbits (at doses of 0.60 times the maximum recommended human dose based on body surface area in mg/m 2 ). (medlibrary.org)
Albendazole was also associated with maternal toxicity in rabbits (at doses of 0.60 times the recommended human dose based on body surface area in mg/m 2 ) ( see Data ). (medlibrary.org)
If you miss a dose of Albendazole, take it as soon as possible. (amdprojects.de)

dexamethasone increases levels of albendazole by unspecified interaction mechanism. (medscape.com)

ALBENZA (albendazole) is an orally administered broad-spectrum anthelmintic. (nih.gov)

Albendazole can achieve good results (95%-100% efficacy after a 10-day course of treatment) if treatment is initiated within 72 hours of ingestion of the egg-containing raccoon feces. (wikipedia.org)
Albendazole has a similar efficacy to thiabendazole, but fewer side effects. (wikipedia.org)
However, there is no definitive agreement as to how the efficacy of praziquantel is best expressed. (plos.org)
We put together a database from various studies of the efficacy of praziquantel against schistosomiasis. (plos.org)

Cimetidine: Increased albendazole sulfoxide concentrations in bile and cystic fluid by about 2-fold in hydatid cyst patients. (nih.gov)
Albendazole sulfoxide concentrations in bile and cystic fluid were increased (about 2-fold) in hydatid cyst patients treated with cimetidine (10 mg/kg/day) (n = 7) compared with albendazole (20 mg/kg/day) alone (n = 12). (medlibrary.org)

Albendazole concentrations are negligible or undetectable in plasma as it is rapidly converted to the sulfoxide metabolite prior to reaching the systemic circulation. (nih.gov)
The systemic anthelmintic activity has been attributed to the primary metabolite, albendazole sulfoxide. (nih.gov)
Oral bioavailability appears to be enhanced when albendazole is coadministered with a fatty meal (estimated fat content 40 g) as evidenced by higher (up to 5-fold on average) plasma concentrations of albendazole sulfoxide as compared to the fasted state. (nih.gov)
Maximal plasma concentrations of albendazole sulfoxide are typically achieved 2 to 5 hours after dosing and are on average 1.31 mcg/mL (range 0.46 to 1.58 mcg/mL) following oral doses of albendazole (400 mg) in 6 hydatid disease patients, when administered with a fatty meal. (nih.gov)
Following 4 weeks of treatment with albendazole (200 mg three times daily), 12 patients' plasma concentrations of albendazole sulfoxide were approximately 20% lower than those observed during the first half of the treatment period, suggesting that albendazole may induce its own metabolism. (nih.gov)
Limited in vitro and clinical data suggest that albendazole sulfoxide may be eliminated from cysts at a slower rate than observed in plasma. (nih.gov)
Albendazole is rapidly converted in the liver to the primary metabolite, albendazole sulfoxide, which is further metabolized to albendazole sulfone and other primary oxidative metabolites that have been identified in human urine. (nih.gov)
Biliary elimination presumably accounts for a portion of the elimination as evidenced by biliary concentrations of albendazole sulfoxide similar to those achieved in plasma. (nih.gov)
However, since renal elimination of albendazole and its primary metabolite, albendazole sulfoxide, is negligible, it is unlikely that clearance of these compounds would be altered in these patients. (nih.gov)
In patients with evidence of extrahepatic obstruction (n = 5), the systemic availability of albendazole sulfoxide was increased, as indicated by a 2-fold increase in maximum serum concentration and a 7-fold increase in area under the curve. (nih.gov)
The rate of absorption/conversion and elimination of albendazole sulfoxide appeared to be prolonged with mean T max and serum elimination half-life values of 10 hours and 31.7 hours, respectively. (nih.gov)
Although no studies have investigated the effect of age on albendazole sulfoxide pharmacokinetics, data in 26 hydatid cyst patients (up to 79 years) suggest pharmacokinetics similar to those in young healthy subjects. (nih.gov)
Praziquantel: In the fed state increased mean maximum plasma concentration and area under the curve of albendazole sulfoxide by about 50% in healthy subjects. (nih.gov)
In the fed state, praziquantel (40 mg/kg) increased mean maximum plasma concentration and area under the curve of albendazole sulfoxide by about 50% in healthy subjects (n = 10) compared with a separate group of subjects (n = 6) given albendazole alone. (medlibrary.org)
Albendazole sulfoxide plasma concentrations were unchanged 4 hours after dosing. (medlibrary.org)
Concentrations of albendazole and the active metabolite, albendazole sulfoxide, have been reported to be low in human breast milk. (medlibrary.org)

Albendazole can be given with diethylcarbamazine to lower microfilaremia levels. (wikipedia.org)

These highlights do not include all the information needed to use ALBENDAZOLE TABLETS safely and effectively. (nih.gov)
See full prescribing information for ALBENDAZOLE TABLETS. (nih.gov)
Albendazole tablets should be taken with food. (nih.gov)
Patients with known hypersensitivity to the benzimidazole class of compounds or any components of albendazole tablets. (nih.gov)

We analyzed data from 24 studies conducted at African, Asian, and Latin American sites, enrolling overall 4,740 individuals infected with Schistosoma mansoni , S . haematobium , or S . japonicum , and treated with praziquantel at doses of 40-80 mg/kg. (plos.org)
Should I start with low doses of albendazole on that schedule and add praziquantel? (curezone.com)
I ve started 200 mg albendazole at, 4 doses per da. (curezone.com)

The control of schistosomiasis emphasizes preventive chemotherapy with praziquantel, which aims at decreasing infection intensity and thus morbidity in individuals, as well as transmission in communities. (plos.org)

Alveolar and cystic echinococcosis may require lifelong treatment with albendazole, which only prevents the parasites from growing and reproducing rather than killing them. (wikipedia.org)

In women, d'évoluer en hydronéphrose et de créer des urogenital schistosomiasis may cause conditions propices au développement d'un vaginal bleeding, pain during sexual cancer de la vessie. (who.int)
The drug praziquantel is used against the parasitic disease schistosomiasis. (plos.org)

Theophylline because the risk of its side effects may be increased by Albendazole. (amdprojects.de)

grapefruit will increase the level or effect of albendazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)
Monitor Closely (1) grapefruit will increase the level or effect of albendazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)

Monitor liver enzymes before the start of each treatment cycle and at least every 2 weeks while on albendazole therapy and discontinue if clinically significant elevations occur. (nih.gov)
Praziquantel is used to treat schistosoma (infection with a type of worm that lives in the bloodstream) and liver fluke (infection with a type of worm that lives in or near the liver). (optionrx.com)
Lab tests, including complete blood cell counts and liver function, may be performed while you use Albendazole. (amdprojects.de)

Albendazole is a broad-spectrum anthelmintic and antiprotozoal agent of the benzimidazole type. (wikipedia.org)

Albendazole therapy for neurocysticercosis: a prospective double-blind trial comparing 7 versus 14 days of treatment. (nih.gov)
Drug Treatment of Hydatid Cyst With Albendazole and Praziquantel in Humans. (jptcp.com)

Plasma concentrations of parent albendazole were measurable in only 1 of 5 patients. (nih.gov)

Hydatid disease: 28-day cycle followed by 14-day albendazole-free interval for a total of 3 cycles. (nih.gov)

you are allergic to any ingredient in Albendazole or to benzimidazoles (eg, rabeprazole). (amdprojects.de)

Some medicines can affect how praziquantel works. (optionrx.com)
Some medicines may interact with Albendazole. (amdprojects.de)
Ask your health care provider if Albendazole may interact with other medicines that you take. (amdprojects.de)

Praziquantel is in a class of medications called anthelmintics. (nih.gov)

Praziquantel has its side and anthelmintic activity to inhibit enzyme systems carbohydrate metabolism, increases the permeability of cell membranes to calcium, followed by muscle paralysis cestode, vacuolization and disintegration of the integument. (petmedsmex.com)

The pharmacokinetics of albendazole in patients with impaired renal function have not been studied. (nih.gov)
The pharmacokinetics of praziquantel were unchanged following co-administration with albendazole (400 mg). (medlibrary.org)

Albendazole (ADZ) and praziquantel (PZQT) have been used as anthelmintics for over 30 years. (nih.gov)

Ordnung Albendazole '' Online Ohne Rezept. (amdprojects.de)

Each white to off-white, film-coated tablet contains 200 mg of albendazole. (nih.gov)

fosphenytoin decreases levels of albendazole by increasing metabolism. (medscape.com)

Albendazole is poorly absorbed from the gastrointestinal tract due to its low aqueous solubility. (nih.gov)

Albendazole is a white to off-white powder. (nih.gov)

I had it too and I took Praziquantel and the pain in my abdomen, bladder, kidneys went away. (curezone.com)

Store Albendazole at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. (amdprojects.de)

Based on findings from animal reproduction studies, albendazole may cause fetal harm when administered to a pregnant woman. (medlibrary.org)
Albendazole has been shown to be teratogenic (to cause embryotoxicity and skeletal malformations) in pregnant rats and rabbits. (medlibrary.org)
If you are a woman who may become pregnant, you should have a negative pregnancy test before you start taking Albendazole. (amdprojects.de)
Pregnancy and breast-feeding: Do not use Albendazole if you are pregnant. (amdprojects.de)

Anatomy1

Organisms34

Diseases39

Chemicals and Drugs22

Analytical, Diagnostic and Therapeutic Techniques and Equipment5

Health Care2

Geographicals4

Ivermectin12

Niclosamide5

Mebendazole2

Tapeworm infections2

Elimination half-life of albendazole sulf2

Antiparasitic4

Cysticercosis3

Dose16

Dexamethasone1

ALBENZA1

Efficacy4

Cimetidine2

Sulfoxide16

Diethylcarbamazine1

Tablets4

Doses3

Chemotherapy1

Parasites1

Schistosomiasis2

Theophylline1

Intestinal2

Liver3

Broad-spectrum1

Treatment2

Concentrations1

Hydatid1

Benzimidazoles1

Medicines3

Medications1

Anthelmintic activity1

Pharmacokinetics2

Anthelmintics1

Rezept1

Film coated1

Metabolism1

Gastrointestinal1

Powder1

Bladder1

Room temperature1

Pregnant4