• SAN DIEGO, July 22, 2021 /PRNewswire/ - NuVasive, Inc. (NASDAQ: NUVA), the leader in spine technology innovation, focused on transforming spine surgery with minimally disruptive, procedurally integrated solutions, announced today the commercial launch of Modulus ® ALIF, a 3D-printed porous titanium implant for anterior lumbar interbody fusion (ALIF), in targeted global regions. (nuvasive.com)
  • There was a large increase in the amount of mineralised bone within the porous Ti layer when the implant was coated with anatase TiO 2 . (inderscience.com)
  • According to Dr. J. A. Gerber, probing pressure around an implant should not exceed 0.15 Newtons (0.15N). 7 Follow the 'simple six' rule that takes into consideration the osseointegration and regenerative procedures to wait six months after the implant has been restored before probing. (rdhmag.com)
  • UV11 - Conical 11 dgr connection Regular Platform Pure & Porous dental implant UV11 dental implant with highly developed porosity and high surface cleanliness in accordance with RBM type of surface treatment. (uniqa.dental)
  • Kevin Foley, MD, Chairman of Semmes-Murphey Neurologic and Spine Institute and professor of neurosurgery, orthopedic surgery and biomedical engineering at the University of Tennessee Health Science Center stated, "The Inspire porous PEEK technology checks all of the boxes for an ideal interbody implant: fully interconnected porosity, modulus of elasticity equivalent to cancellous bone, strong biomechanical properties, radiolucency, and a bioactive surface for osseointegration. (rocklandreviewnews.com)
  • and despite the good osseointegration of Titanium, it is still not good enough and there is a high amount of implant loosening due to the failure of the interface between Titanium and bone. (us.es)
  • Titanium is the major component of most dental implant systems, since it exhibits excellent biocompatibility and supports osseointegration. (springer.com)
  • By combining these 2 materials, researchers hope to improve osseointegration-the direct structural and functional connection between living bone and the implant-while maintaining the desirable mechanical properties associated with PEEK, such as lower stiffness and better load distribution. (e-neurospine.org)
  • Research on implant surface topography has been of major focus and new surfaces are constantly applied on implants (7) in an attempt to accelerate osseointegration rates. (dentalmedjournal.it)
  • Bu çalışma, en yaygın olarak kullanılan implant biyomalzemeleri Ti ve Ti6Al4V alaşımlarının mekanik özellikleri, biyouyumlulukları ve bu biyomalzemelerin mevcut uygulamaları bakımından eklemeli imalat çalışmalarını farklı perspektiflerden incelemektedir. (acarindex.com)
  • Implant biomaterials should have high fatigue, wear and corrosion resistance, stability, osteogenesis and osseointegration properties as well as long lifespan to achieve an intended function. (acarindex.com)
  • We report the 1-year results of a prospective, singlecenter clinical study in which a posterior lumbar interbody fusion (PLIF) was performed using a novel porous polyether ether ketone (PEEK) implant and pedicle screw fixation in patients with symptomatic single-level degenerative lumbar disc disease. (scitechnol.com)
  • All patients underwent a single level PLIF procedure using a porous PEEK implant with pedicle screw fixation and bone marrow concentrate applied to a ceramic carrier. (scitechnol.com)
  • We found that used of a porous-surface PEEK implant with bone marrow concentrate on a ceramic carrier is a clinically viable alternative for improving the osseointegration and fusion rates in patients undergoing single-level PLIF surgery for degenerative disc disease in the lumbar spine. (scitechnol.com)
  • Three-dimensional porous metallic structures are of great importance for implant surgery since such structures promote the in-growth of natural human bone cells (osseointegration). (ronald-simmonds.de)
  • Innovative implant surfaces for cementless anchoring have been generated with the aid of a porous titanium coating for many years now. (dot-coating.de)
  • In addition to its metal coating capabilities, DOT is able to apply a porous titanium coating on implant components consisting of temperature resistant plastic (PEEK) or ceramics. (dot-coating.de)
  • Using porous titanium coating,a firmly adherent pure titanium layer can be applied on the implant giving the bone a suitable surface for ingrowth and osseointegration. (dot-coating.de)
  • A typical application in the medical field is the production of human acetabular cups with high stability and a complex surface structure that facilitates osseointegration, in other words, the organic fusion of bone tissue with the surface of the bone implant. (mastars.com)
  • In total joint replacement in particular, it is important that the implant has a roughened, and ideally porous, structure to which new bone can attach and mechanically anchor itself. (3dprint.com)
  • This process, called osseointegration, ensures that the implant will be well fixated in the patient bone in order to support the forces of daily living. (3dprint.com)
  • Osseointegration, as applied to dental implants, refers to the postinsertion result in which medullary bone has grown up to or into the material of the implant without interposition of a connective tissue layer between the bone and the alloplastic implant material. (medscape.com)
  • Both mechanisms can facilitate retention of an implant, but osseointegration is considered more suitable for long-term implant success. (medscape.com)
  • Porous materials allow for easier osseointegration of implants and their firmer connection with the bone. (iospress.com)
  • The platform contains 3D printed cellular titanium implants that feature porous macro - , micro-, and nanostructures designed to mimic cortical and cancellous bone to facilitate intervertebral fusion. (aofoundation.org)
  • CONDUIT™ Implants are designed with an interconnected pore structure making them 80% porous (700 μm pore size) compared with the typical 50-90% porosity of natural cancellous bone [1−6] ( Fig 2 ). (aofoundation.org)
  • The implants' porous structure enables excellent visualization both intraoperatively and postoperatively on imaging modalities without interference ( Fig 3 ). (aofoundation.org)
  • Effect of pore size on bone ingrowth into porous titanium implants fabricated by additive manufacturing: an in vivo experiment. (aofoundation.org)
  • Osteoinduction of porous Ti implants with a channel structure fabricated by Selective Laser Melting. (aofoundation.org)
  • A pronounced effect of the hydrothermally prepared TiO 2 coating was seen with the in vivo test where Ti6Al4V implants with a porous Ti layer on the surface were implanted in rabbit tibia for ten weeks. (inderscience.com)
  • The surface of dental implants are also porous so the bone tissue and blood vessels around it can bond together. (cancuncosmeticdentistry.com)
  • R1] Bansiddhi A., Sargeant T. D., Stupp S. I., Dunand D. C., 2008, "Porous NiTi for bone implants: A review", Acta Biomaterialia 4 (2008) 773-782. (unipv.it)
  • One advantage of NPs as a coating for dental implants when not embedded in a film but applied directly to the titanium is that, with careful control of the doping and distribution, their small size provides the opportunity to leave the majority of the titanium surface uncoated and thus available for osteoblast colonisation and subsequent osseointegration. (springer.com)
  • These hybrid implants seek to harness the biocompatibility and favorable mechanical properties of PEEK, along with the enhanced osseointegration potential of Ti. (e-neurospine.org)
  • Biomaterial research regarding dental implants have dominantly utilized titanium as a material of choice and both basic and clinical research show that commercially pure titanium and several of other titanium alloys are osteoconductive and promote osseointegration (4). (dentalmedjournal.it)
  • Certain prerequisites have been proposed as essential factors for successful osseointegration (6) and the development and evolution of the dental implants progressed based on these factors. (dentalmedjournal.it)
  • In this context, 3D printable biomaterials are suitable candidates for implants and the amount of additively-manufactured implants is significantly increasing due to their unique properties which are biocompatible, versatile and adaptable, have relevant mechanical (strength and stiffness) and biological functionalities, porous structure, design freedom, provide material save, produce with good accuracy, fulfill design requirements in geometry. (acarindex.com)
  • For example, a potential project could focus on structural optimization of porous titanium for patient-specific implants (tailored stiffness, strength and improved osseointegration). (nmsu.edu)
  • A porous TPS coating is applied on the implants using a vacuum plasma spray process to modify the surface of ceramic implants and thus to make the surface attractive for improved osseointegration. (dot-coating.de)
  • In machined surface implants the diabetes interfere negatively in osseointegration while acid-etched surface promoted major BIC and BD index, indicating its selective use in diabetic patients. (bvsalud.org)
  • Many changes in bone metabolism associated with diabetes can consequently affect the process of osseointegration of dental implants. (bvsalud.org)
  • In the 1960s, Branemark introduced the concept of osseointegration as it applies to dental implants. (medscape.com)
  • This study aimed to compare the Regenerex (VR) to the non-interconnecting pore structure Porous Plasma Spray (VP) on tibial implants for total knee arthroplasty (TKA) at 5 years. (lu.se)
  • Remarkably, immunofluorescence staining, micro-CT, histological, and biomechanical tests demonstrated that the sustained release of both BMP-2 and OPG from composite scaffolds significantly improved bone ingrowth and osseointegration in osteoporotic defects. (figshare.com)
  • Curiteva pioneered and received clearance of the world's first 3D printed, fully interconnected porous PEEK structure, utilizing internally developed Fused Filament Fabrication. (rocklandreviewnews.com)
  • HUNTSVILLE, Ala., April 14, 2023 (Newswire.com) - Huntsville, AL based technology company, Curiteva announced a limited commercial release utilizing its recently FDA-cleared Inspire Porous PEEK HA FUSE Cervical Interbody System. (rocklandreviewnews.com)
  • Por otro lado, las técnicas que se han realizado para mejorar la oseointegración del titanio han sido: ataque químico para modificar la morfología de la superficie y conversión de la superficie en bioactiva, mediante deposición electroforética de compuestos de vidrio bioactivo/chitosan y vidrio bioactivo/PEEK y mediante sol-gel de hidroxiapatita sintética. (us.es)
  • This white paper examines findings from both in-vitro and in-vivo studies on new porous PEEK technology. (beckershospitalreview.com)
  • New porous PEEK technology produced higher osseointegration capability when compared to solid PEEK, solid titanium and porous titanium in cell culture. (beckershospitalreview.com)
  • Titanium Coating On PEEK For Medical Devices Porous titanium coatings onto polymers are of great interest tomedical industries. (orchid-ortho.com)
  • A vacuum plasma spray (VPS) process has been developed to coat PEEK with a micro porous biomimetic titanium coating. (orchid-ortho.com)
  • The porous surface architecture is engineered to participate in fusion and promote new bone on-growth and in-growth. (nuvasive.com)
  • Porous coated materials can provide early mechanical stabilization preventing early micromotion due to their increased surface. (orchid-ortho.com)
  • Porous coating provides a rough surface for frictional resistance as well as an excellent surface for bone ingrowth. (biomedcentral.com)
  • 16 Further, it was found that porous HA (Interpore BioMed Interpore Cross International, Irvine, Calif) attracted internal bone growth when placed on the surface of viable bone. (allenpress.com)
  • Article: Improvement of osseointegration of Ti and Ti-alloys by hydrothermally prepared bioactive anatase coating Journal: International Journal of Nano and Biomaterials (IJNBM) 2015 Vol.6 No.1 pp.18 - 28 Abstract: This paper reports on the in vivo behaviour of Ti6Al4V alloy substrates with or without a porous Ti layer that were coated with a thin layer of anatase TiO 2 by a hydrothermal treatment. (inderscience.com)
  • This paper reports on the in vivo behaviour of Ti6Al4V alloy substrates with or without a porous Ti layer that were coated with a thin layer of anatase TiO 2 by a hydrothermal treatment. (inderscience.com)
  • TPS Technical Information Sheet TPS (Titanium Plasma Spray) Coating is a porous coating made using vacuum plasma spary process that can be applied on: Ti6AL4V, Ti6AL4V Eli, CoCr and TiC substrate materials. (orchid-ortho.com)
  • To construct three-dimensional (3D)-printed composite scaffolds for implantation, a hydrogel loaded with drugs was injected into porous Ti6Al4V scaffolds. (figshare.com)
  • Porous titanium-6 aluminum-4 vanadium cage has better osseointegration and less micromotion than a poly-ether-ether-ketone cage in sheep vertebral fusion. (aofoundation.org)
  • Incorporating simvastatin/poloxamer 407 hydrogel into 3D-printed porous Ti 6 Al 4 V scaffolds for the promotion of angiogenesis, osseointegration and bone ingrowth. (bvsalud.org)
  • In conclusion, this study demonstrated that the BMP-2- and OPG-loaded 3D-printed composite scaffolds can potentially promote osseointegration for osteoporotic patients after joint replacement. (figshare.com)
  • On-Growth and In-Growth Osseointegration Enhancement in PM Porous Ti-Scaffolds by Two Different Bioactivation Strategies: Alkali Thermochemical Treatment and RGD Peptide Coating. (irsjd.org)
  • Porous NiTi alloys combine benefits from shape memory effects and porous structure. (unipv.it)
  • R3] Zhu S. L., Yang X. J., Fu D. H., Zhang L. Y., Li C. Y. and CY Z. D., 2005, "Stress-strain behavior of porous NiTi alloys prepared by powders sintering", Mater Sci Eng A - Struct Mater Prop Microstruct Proc 408 (2005) 264-268. (unipv.it)
  • Ti alloys offer superior strength, biocompatibility, and osseointegration capabilities, making them ideal for promoting spinal fusion and ensuring long-term stability. (e-neurospine.org)
  • is a porous titanium construct with a 3D interconnecting pore structure and biomechanical characteristics close to that of normal trabecular bone. (lu.se)
  • In particular, the porous trabecular structure of bone can be approximated using 3D printing. (3dprint.com)
  • Modulus is designed for enhanced osseointegration, 1 biomechanical, 1 and imaging properties. (nuvasive.com)
  • The metallic material that best fits to the requirements of being a bone replacement is Titanium, thanks to its excellent balance between biomechanical (low stiffness and density) and biofunctional (biocompatible, corrosion resistant and good osseointegration) properties. (us.es)
  • The purpose of this study was to determine the effect of stem diameter on torsional stability in a biomechanical analysis of cadaveric femurs, as well as investigate the length of cortical contact necessary to obtain sufficient torsional stability for osseointegration. (biomedcentral.com)
  • The REDAPT™ Fully Porous Shell is fabricated through additive manufacturing, which permits greater design flexibility compared to standard, subtractive manufacturing (i.e., machining). (snvideos.com)
  • Conclusion: Highly porous titanium cups produced using an additive manufacturing and electron beam melting technology achieved reliable midterm clinical and radiographic results not inferior to those of second-generation cups. (unime.it)
  • Fig 2: Interconnected porous structure that mimics cortical and cancellous bone. (aofoundation.org)
  • Its porous nature makes it incredibly biocompatible, yet it's strong enough to stand in for bones in the skull, limbs, and even the spine. (in-vision.at)
  • In terms of corrosion behaviour, specimens with a lower porosity were not much different from the non-porous material. (iospress.com)
  • On the one hand, porous Ti has been fabricated using the space-holder technique to achieve a 50 % porosity sample with different pore sizes (100-200 μm, 250-355 μm, 355-500 μm). (us.es)
  • This work tackles a suitable solution for both problems: porous c.p. (us.es)
  • It demonstrates poor osseointegration due to its proclivity to form biofilms, potentially affecting the fusion process and long-term stability. (e-neurospine.org)
  • One thing is certain: the acetabular cup consists of a fixed profile that ensures optimal stability and a carefully designed porous structure that effectively promotes osseointegration. (mastars.com)
  • In vivo studies with similar porous titanium materials show that bony in-growth increases at the 500−700 μm pore size range compared with larger or smaller pores [2−4] . (aofoundation.org)
  • In vitro studies [1] have reported more significant osteoblastic differentiation in human stem cells cultured on similar porous titanium constructs than solid titanium surfaces. (aofoundation.org)
  • Highly repeatable and consistent porous structures may be realised with strut sizes down to 100µm. (medicaldevice-network.com)
  • Dr. Drach's research deals with mechanics of heterogeneous materials including composite and porous materials. (nmsu.edu)
  • Porous NiTi device for lumbar fusion (Actipore by Biorthex, Canada). (unipv.it)
  • Additionally, new reports support the use of bovine porous bone mineral as an acceptable heterogeneous grafting material. (aetna.com)
  • These procedures may include the use of autogenous bone or various types of freeze-dried or decalcified freeze-dried bone graft materials from tissue banks or commercially processed bovine porous bone mineral. (aetna.com)
  • Osseointegration can be contrasted with fibroosseous integration, in which there is a soft-tissue interface that is viewed as the equivalent of the periodontal ligament that surrounds the tooth. (medscape.com)
  • Research on porous NiTi is still required in order to successfully exploit this material in orthopedics. (unipv.it)
  • Because it's a natural material, it is praised for its osseointegration possibilities. (in-vision.at)
  • Twenty-four cadaveric femoral specimens were implanted with a fully porous-coated stem. (biomedcentral.com)
  • Furthermore, a minimum of 3 cm or 4 cm of diaphyseal contact with a porous-coated stem should be achieved in proximal femoral bone deficiency and will likely be dependent on the stem diameter utilized at the time of surgery. (biomedcentral.com)
  • Objective: Highly porous titanium cups have been recently introduced, with contradictory outcomes. (unime.it)
  • After arthroplasty in patients with osteoporosis, poor interface osseointegration resulting from insufficient bone regeneration ability often leads to catastrophic complications such as prosthesis displacement and loosening and periprosthetic fractures. (figshare.com)
  • Both groups showed similar radiographic parameters regarding osseointegration, which were stable over the time. (unime.it)