• He taught biochemistry, biophysics and physiology. (wikipedia.org)
  • Introduces the requisite organic, physical, and biochemistry for incoming bioengineers to understand biological systems at the molecular level. (washington.edu)
  • An overview of the physiology and biochemistry of vitamin B12 and folate under normal and pathological conditions is included. (medscape.com)
  • Cation occlusion is now considered an essential property of all ATP-driven cation pumps and also other coupled cation transport systems (e.g. cation exchangers or co-transport proteins). (wikipedia.org)
  • Transport proteins that are involved in this type of transport are referred to as cotransporters or symporters. (physiologyweb.com)
  • Movement across a biological membrane is more complicated and is a function of lipid solubility of the ion/molecule as well as the presence of channels or transport proteins that can allow the ion/molecule to cross the membrane (see Lipid Bilayer Permeability and Summary of Membrane Transport Processes ). (physiologyweb.com)
  • Microtubules also function as highly active railways, transporting proteins, energy-producing mitochondria, organelles and other materials from the body of the brain cell to distant parts connecting it to other cells. (usf.edu)
  • These vesicles are carriers of active or non-autonomous function biomolecules, such as proteins, lipids, DNA, mRNA and non-coding regulatory RNA. (spandidos-publications.com)
  • We study the interaction between proteins in biological fluids as well as single proteins to nanomaterials of different kinds. (lu.se)
  • Conceptualization and mathematical modeling of how membrane channels, carriers and pumps work to transport molecules across the cell membrane. (wikipedia.org)
  • The kinetic equations of membrane transport were developed by Stein, together with William Lieb, and published in "Transport and Diffusion Across Cell Membranes", a comprehensive treatment of transport kinetics. (wikipedia.org)
  • The driving forces for solute transport at membrane level in plants are same as those in the other biological membrane systems. (biologydiscussion.com)
  • For non-equilibrium conditions, the active transport may be identified by the flux ratio for an ionic species across the membrane. (biologydiscussion.com)
  • But this tells us nothing directly of the transport of ions across the membrane. (biologydiscussion.com)
  • If the active transport involves the movement of a charged ion-carrier complex across the membrane, then it is termed as electrogenic process. (biologydiscussion.com)
  • This carrier combines with permeant and transports it across the membrane. (biologydiscussion.com)
  • A type of secondary active transport across a biological membrane in which a transport protein couples the movement of an ion (usually Na + or H + ) down its electrochemical gradient to the movement of another ion or molecule against a concentration or electrochemical gradient. (physiologyweb.com)
  • The concentration gradient may exist across a biological membrane, where the concentration is higher on one side of the membrane compared to the other side. (physiologyweb.com)
  • Cloride (Cl − ) plays an important role in several physiological processes such as the action potential of skeletal muscle cells, CO 2 transport in blood (via Cl − /bicarbonate exchange across the plasma membrane of red blood cells), and many other processes. (physiologyweb.com)
  • An electrogenic transport process is one that leads to the translocation of net charge across the membrane. (physiologyweb.com)
  • Plasma membrane redox system (PMRS) is an electron transport chain system ubiquitously present throughout all cell types. (hindawi.com)
  • Curcumin, isolated from Curcuma longa, has modulatory effects on cellular physiology due to its membrane interaction ability and antioxidant potential. (hindawi.com)
  • Plasma membrane redox system (PMRS) is an electron transport chain system ubiquitously present in all cell types that transfers electrons from intracellular substrates to extracellular acceptors maintaining redox homeostasis for a successful cell physiology [ 1 ]. (hindawi.com)
  • Laurence Irving was a pioneer in the field of comparative physiology. (uaf.edu)
  • Irving studied and published on many topics in comparative physiology, ranging through matters as diverse as metabolism and respiration in starfish, development of trout embryos, blood supply in mammalian brains, adaptations of seals to diving, blood transport of respiratory gases in fishes, respiration of porpoises and manatees, cold adaptation in arctic birds and mammals including humans, and environmental adaptations of native arctic peoples. (uaf.edu)
  • Besides Stein's contribution to concepts in kinetics, biology, and medicine, he also, together with Eric Barnard, conducted work on the first labeling of the active center of an enzyme, ribonuclease, identifying histidine residue 119. (wikipedia.org)
  • In the context of exploring lymphatic physiology, students in Dr. Dixon's laboratory learn to weave together techniques in molecular and cell biology, biomechanics, imaging, computer programming, and image and signal processing to provide insight into the regulation of lymphatic physiology. (gatech.edu)
  • 1974. In: Biological handbooks: Biology data book, Volume III, second edition. (cdc.gov)
  • Moreover, applications of such models arise in several biophysical phenomena in different fields such as, for instance, biology, medicine and electronics, where, by means of nanoscale memristor networks, scientists seek to reproduce the behavior of biological synapses. (mdpi.com)
  • Mathematical Biology is the application of mathematical modelling to solve problems in biology and physiology. (gla.ac.uk)
  • His investigations contributed substantially to our understanding of the enzymology, genetics, and regulation of this major pathway of biological nitrogen acquisition. (geniustudies.com)
  • Fulvic Acid can now freely, without restriction of these unwanted salt acids, transport nutrients into our cells , as it was made to do. (optimallyorganic.com)
  • Alexa Woo, PhD, assistant professor of molecular pharmacology and physiology and member of the Byrd Alzheimer's Center, was the study's lead author. (usf.edu)
  • Alexa Woo, PhD, an assistant professor of molecular pharmacology and physiology at the USF Health Morsani College of Medicine, was the paper's lead author. (usf.edu)
  • He is the author of numerous papers and review articles on biochemical, genetic, and molecular biological aspects of inorganic nitrogen metabolism. (geniustudies.com)
  • Circadian rhythmicity of active GSK3 isoforms modulates molecular clock gene rhythms in the suprachiasmatic nucleus. (rochester.edu)
  • The broad range of curcumin's biological properties is due to its ability to bind to over 100 identified different molecular targets [ 17 ]. (hindawi.com)
  • TIAs have a wide variety of different molecular structures and biological activities [ 11 ]. (biomedcentral.com)
  • To enhance our understanding of the molecular mechanism of substrate cleavage, we have solved the crystal structures of human GGT1 (hGGT1) with glutathione (a substrate) and a phosphate-glutathione analog (an irreversible inhibitor) bound in the active site. (bvsalud.org)
  • Gradually, I changed methodologies, biochemical, molecular biological and physiological, and I have had the pleasure of being part of how plant respiration over time has proven to be involved in many fundamental life processes, developing a more integrated view of plant metabolism. (lu.se)
  • As a result of this self-organization, cells drive fluid flows that circulate around the colony at a constant peak speed of ~30 µm s −1 , providing a stable and high-speed avenue for directed material transport at the macroscopic scale. (nature.com)
  • We previously reported that CD23/FcεRII (low-affinity IgE receptor) is expressed on human intestinal epithelial cells and is responsible for transepithelial transport of IgE. (mcmaster.ca)
  • Our results indicate that CD23 expression in these human intestinal epithelial cells is mediated through the p38 MAPK pathway and that inhibition of p38 MAPK consequently interferes with the transport of IgE and immune complexes across the intestinal epithelial barrier. (mcmaster.ca)
  • Recent evidence from our lab suggests that this process involves active uptake into lymphatics by the lymphatic endothelial cells. (gatech.edu)
  • They did not know, however, the identity of the active substances, just as cancer researchers understood little of the unregulated growth of tumour cells. (nobelprize.org)
  • Their multi‑functional cargo have been indicated to regulate a vast number of biological pathways in target cells. (spandidos-publications.com)
  • Exosomes are small lipid bilayer-surrounded extracellular vesicles released from cells into the extracellular space or biological fluids ( 1 , 2 ). (spandidos-publications.com)
  • An important finding was that trapping or "occlusion" of the K and Na ions in the protein has the functional role of minimizing wasteful cation leakages through the system, thus ensuring optimal efficiency of energy coupling between ATP (Adenosine Triphosphate) hydrolysis and active Na and K ion movements, 3 Na ions out of and 2 K ions into the cell per cycle, respectively. (wikipedia.org)
  • The Na + /K + ATPase is electrogenic because for every ATP molecule hydrolyzed, 3 Na + ions are transported out of the cell and 2 K + ions are transported into the cell (leading to the translocation of one net positive charge out of the cell). (physiologyweb.com)
  • Due to the low partition coefficient K j of polar solutes, which reflects the high lipid content of cell membranes, the permeability of biological membranes to solute molecules P j is known to decrease with increasing polarity of the permeant. (biologydiscussion.com)
  • Discover the structure, functions, and processes of biological membranes in this comprehensive guide. (thesciencenotes.com)
  • A second central issue lies in the functions of the biological membranes. (lu.se)
  • When solute movement is against potential gradient an active process is involved. (biologydiscussion.com)
  • These structures and the structure of apo-hGGT reveal movement of amino acid residues within the active site as the substrate binds. (bvsalud.org)
  • It serves as an internal transport system for moving essential substances throughout the cell, and in single-celled organisms, such as the AMOEBA, it is responsible for the movement (CELL MOVEMENT) of the entire cell. (bvsalud.org)
  • Velocity distribution of the anterograde and retrograde transport of extracellular particles byAmoeba proteus. (godman-inc.com)
  • Introduces chemical and biochemical reaction kinetics, methods of evaluating kinetic parameters for reaction rate data, and prediction of the performance of biological and biochemical processes. (washington.edu)
  • Aquaporin-4-dependent glymphatic solute transport in the rodent brain. (rochester.edu)
  • In addition to the well known HacA targets such as the ER resident foldases and chaperones, GO enrichment analysis revealed up-regulation of genes involved in protein glycosylation, phospholipid biosynthesis, intracellular protein transport, exocytosis and protein complex assembly in the HacACA mutant. (tu-berlin.de)
  • Studies the principles of combined mass transport in homogeneous and heterogeneous reaction systems as applied to biological processes. (washington.edu)
  • Biological processes over-represented in the down-regulated genes include those belonging to central metabolic pathways, translation and transcription. (tu-berlin.de)
  • The behavioural and biological responses of a child to the obesogenic environment can be shaped by processes even before birth, placing an even greater number of children on the pathway to becoming obese when faced with an unhealthy diet and low physical activity. (who.int)
  • He has authored numerous papers and review articles on active transport of sodium, potassium, and calcium in mammalian systems, on protein kinase C, and on the applications of NMR and EPR spectroscopy to the study of biological systems. (geniustudies.com)
  • In this study, we compared the transport of IgE with that of immune complexes in both the apical-to-serosal and the serosal-to-apical directions across HT29 epithelial cell layers and examined the effects of two p38 MAPK inhibitors, SKF86002 and SB203580, on the expression and function of CD23. (mcmaster.ca)
  • Transepithelial transport of IgE and immune complexes across the epithelial barrier were similarly inhibited. (mcmaster.ca)
  • Intrinsic to the lymphatic system are the varying mechanical forces (i.e., stretch, fluid shear stress) that the vessels encounter as they seek to maintain interstitial fluid balance and promote crucial transport functions, such as lipid transport and immune cell trafficking. (gatech.edu)
  • Hence, the generation of free radicals are part of normal physiology and immune reactions, whereas uncontrolled and chronic production causes local damage ( Beckman and Ames, 1998 ). (dsm.com)
  • Stein collaborated with Felix Bronner, an authority on the physiology of calcium movements, in developing a model that could account for the rates of transmembrane movements of calcium in the face of the cell's extremely low concentrations of the ion. (wikipedia.org)
  • i.e. innate within your physiology provided that you understand some foundational physiological principles. (nfpt.com)
  • The FHA cycle is active inside the cell, detoxifying superoxide anion radicals (O2·-), which are mainly generated as a result of so-called 'electron leakage' to triplet oxygen (O2) in photosynthetic, mitochondrial, peroxisomal, and probably other electron transport chains (Ozyigit et al. (deepdyve.com)
  • Jesper Nygård's research has focused on electron transport in low-dimensional semiconductors, superconductors and nanodevices. (lu.se)
  • Vessel transport function is tracked throughout the procedure by imaging lymphatic uptake of an intradermally injected near infrared (NIR) tracer. (gatech.edu)
  • It is referred to as secondary active transport because no ATP hydrolysis is involved in this process (as opposed to primary active transport). (physiologyweb.com)
  • adapting the crop plants for taking best use of biological pest management approaches. (lu.se)
  • Water is the medium that holds all biological and chemical reactions in the body, resulting in the production of heat and energy metabolism reactions that are required for life support. (articlesfactory.com)
  • Methionine, in turn, is required for the synthesis of S-adenosylmethionine (SAM), a methyl group donor used in many biological methylation reactions, including the methylation of sites in DNA and RNA. (medscape.com)
  • However, cyano-Clbis readily converted into biologically active forms in humans and other mammals. (medscape.com)
  • Conclusions: The results indicate that the constitutive activation of the HacA leads to a coordinated regulation of the folding and secretion capacity of the cell, but with consequences on growth and fungal physiology to reduce secretion stress. (tu-berlin.de)
  • Introduces solid mechanics and interactions of biological structures and medical materials. (washington.edu)
  • The ion/molecule being transported against a chemical or electrochemical gradient is referred to as the driven ion/molecule. (physiologyweb.com)
  • In cotransport, the direction of transport is the same for both the driving ion and driven ion/molecule (into the cell or out of the cell). (physiologyweb.com)
  • This transport process is referred to as active transport because the driven ion/molecule is transported against a concentration or electrochemical gradient. (physiologyweb.com)
  • Current evidence predominantly suggests that chytridiomycosis and WNS outbreaks are driven by anthropogenic transport of novel pathogenic fungi into new geographic regions. (cdc.gov)
  • Dr. Kang also holds the Fleming Endowed Chair in Alzheimer's Research at USF Health and is a biological scientist at James A. Haley Veterans' Administration Hospital. (usf.edu)
  • One such function is the lymphatic transport of dietary lipid from the intestine to the circulation. (gatech.edu)
  • Through the use of tissue-engineered model systems and animal models, our research is shedding light on key functions of lymphatic transport, and the consequence of disease on these functions. (gatech.edu)
  • Introduces momentum and heat transport in medical and biological systems. (washington.edu)
  • Reviews linear and nonlinear systems analysis and control system design and biological and medical applications. (washington.edu)
  • In the in vivo experiment, SE was effective in the treatment of infection after only two days of treatment and was more effective than E and amphotericin B. The S. nitens is active against Candida albicans (C. albicans) and the antifungal potential is being enhanced after incorporation into liquid crystal precursor systems (LCPS). (who.int)
  • The overall outlook regarding research laboratories and themes is promising: the community is numerous, active and there are topics addressing all aspects of animal behavior, especially in large countries like Brazil and Argentina. (bvsalud.org)
  • These results illustrate the combined impact of genetic, lifestyle, and environmental factors in modulating immunological responsivity and emphasize the importance of the exposome in shaping biological responses. (cdc.gov)
  • biological and mechanical properties for several biomedical applications (Montheard et al. (articlesfactory.com)
  • Serious' effects are those that evoke failure in a biological system and can lead to morbidity or mortality (e.g., acute respiratory distress or death). (cdc.gov)
  • He has published multiple important papers in this area and he is senior author on the paper describing the anatomically constrained model of the bee central cortex which is the biological and computational foundation of the project. (lu.se)
  • The energy required to drive transport resides in the transmembrane electrochemical gradient of the driving ion. (physiologyweb.com)
  • Application areas span many topics ranging from electrochemical energy storage, charge and energy transport in correlated materials, light-matter interactions, and how non-covalent interactions influence drug binding, biomolecular structure, and crystal packing. (gatech.edu)
  • During the post-war years he played an important role in the development of U.S. initiative in arctic and Antarctic biological research. (uaf.edu)
  • He then became chief of the physiology section at the newly established Arctic Health Research Center in Anchorage, Alaska (1949-1962). (uaf.edu)
  • Irving was active in research, writing, and professional affairs until his death in 1979. (uaf.edu)
  • Below you will find descriptions of general areas of research currently active in our department. (gatech.edu)
  • Dive into the research topics where Allan Rasmusson is active. (lu.se)
  • The program brings together 12 full-time faculty allowing students to choose from wide range of concentrations such as biological oceanography, chemical oceanography, and physical oceanography. (ubc.ca)
  • 1996. Threshold limit values for chemical substances and physical agents and biological indices for 1995/1996. (cdc.gov)
  • NGF proved to be an extremely potent biological substance. (nobelprize.org)
  • These data show that apoplastic redox-active transition metals are involved in the ascorbate-induced [Ca2+]cyt. (deepdyve.com)
  • Candidates who do not comply with the minimum admission requirements for BSc (Entomology), may be considered for admission to the BSc - Extended programme for the Biological and Agricultural Sciences. (up.ac.za)
  • Interactions between the enzyme and substrate change as the substrate moves deeper into the active site cleft. (bvsalud.org)
  • Understanding the physiology of these structured microbial communities is not only essential to the treatment of chronic infections, but also important to industrial applications, such as bioremediation, anti-biofouling and food hygiene. (nature.com)
  • In collaboration with Steven Karlish at the Weizmann Institute, Stein investigated the kinetic mechanism of active Na and K ion transport, confirming the basic alternating access model of active Na and K transport. (wikipedia.org)
  • Thus, we are also interested in understanding the nature of these forces in both healthy and disease states, such as lymphedema, in order to probe the biological response of the lymphatic system to mechanical forces. (gatech.edu)