Prediction of lymph node metastasis in breast cancer by gene expression and clinicopathological models: Development and validation within a population based cohort. (lu.se)
If the sentinel lymph node is negative for metastasis, it is likely that the neoplasm is still within the location of the primary tumor. (medscape.com)
Cancer124
A retrospective cohort of women diagnosed with invasive, nonmetastatic breast cancer and potentially eligible for these clinical trials was used. (nih.gov)
In the breast cancer clinical trials evaluated for the present study, no criterion precluding recruitment was shared by many or all trials and no specific eligibility criterion was consistently the reason for patients' ineligibility. (nih.gov)
Role of vascular density and normalization in response to neoadjuvant bevacizumab and chemotherapy in breast cancer patients. (curehunter.com)
Local Therapy Decision-Making and Contralateral Prophylactic Mastectomy in Young Women with Early-Stage Breast Cancer. (curehunter.com)
Pneumocystis jiroveci pneumonia (PCP) in patients receiving neoadjuvant and adjuvant anthracycline-based chemotherapy for breast cancer: incidence and risk factors. (curehunter.com)
Tailoring adjuvant chemotherapy regimens for patients with triple negative breast cancer. (curehunter.com)
Phase II study of tivantinib (ARQ 197) in patients with metastatic triple-negative breast cancer. (curehunter.com)
Phase II Study of Lapatinib in Combination With Trastuzumab in Patients With Human Epidermal Growth Factor Receptor 2-Positive Metastatic Breast Cancer: Clinical Outcomes and Predictive Value of Early [18F]Fluorodeoxyglucose Positron Emission Tomography Imaging (TBCRC 003). (curehunter.com)
Randomized Phase III Trial of Paclitaxel Once Per Week Compared With Nanoparticle Albumin-Bound Nab-Paclitaxel Once Per Week or Ixabepilone With Bevacizumab As First-Line Chemotherapy for Locally Recurrent or Metastatic Breast Cancer: CALGB 40502/NCCTG N063H (Alliance). (curehunter.com)
Racial and Ethnic Differences in Breast Cancer Survival: Mediating Effect of Tumor Characteristics and Sociodemographic and Treatment Factors. (curehunter.com)
Molecular Phenotype of Breast Cancer According to Time Since Last Pregnancy in a Large Cohort of Young Women. (curehunter.com)
Variation in type of adjuvant chemotherapy received among patients with stage I breast cancer: A multi-institutional study. (curehunter.com)
Background Hormone receptor (HR)-positive breast cancer is a disease for which no immune checkpoint inhibitors have shown promise as effective therapies. (bmj.com)
Methods This non-randomized, multicohort, phase II study evaluated the efficacy and safety of the anti-PD-1 antibody nivolumab 240 mg administered every 2 weeks in combination with the CDK4/6 inhibitor abemaciclib 150 mg twice daily and either fulvestrant (FUL) or letrozole (LET) as a first-line or second-line treatment for HR-positive HER2-negative metastatic breast cancer. (bmj.com)
A recessive variant of XRCC4 predisposes to non- BRCA1/2 breast cancer in chinese women and impairs the DNA damage response via dysregulated nuclear localization. (duke.edu)
PURPOSE: To define the biology driving the aggressive nature of breast cancer arising in young women. (duke.edu)
An integrated approach to the prediction of chemotherapeutic response in patients with breast cancer. (duke.edu)
Assessing risk of breast cancer in an ethnically South-East Asia population (results of a multiple ethnic groups study). (duke.edu)
Breast cancer as heterogeneous disease: contributing factors and carcinogenesis mechanisms. (duke.edu)
The observed bimodal patterns of breast cancer incidence in the U.S. suggested that breast cancer may be viewed as more than one biological entity. (duke.edu)
Co-occurring Fatigue and Lymphatic Pain Incrementally Aggravate Their Negative Effects on Activities of Daily Living, Emotional Distress, and Overall Health of Breast Cancer Patients. (duke.edu)
Fatigue and lymphatic pain are the most common and debilitating long-term adverse effects of breast cancer treatment. (duke.edu)
Distinct Receptor Tyrosine Kinase Subsets Mediate Anti-HER2 Drug Resistance in Breast Cancer. (duke.edu)
Each year, more people die of lung cancer than of colon, breast, and prostate cancers combined. (hindawi.com)
Scholars@Duke publication: Trilaciclib prior to gemcitabine plus carboplatin for metastatic triple-negative breast cancer: phase III PRESERVE 2. (duke.edu)
Triple-negative breast cancer (TNBC) is an aggressive malignancy for which cytotoxic chemotherapy remains the backbone of treatment. (duke.edu)
This phase III trial compares denosumab to placebo for the prevention of breast cancer in women with a BRCA1 germline mutation. (clinicaltrials.gov)
Research has shown that denosumab may also reduce the risk of developing breast cancer in women carrying a BRCA1 germline mutation. (clinicaltrials.gov)
I. To evaluate the reduction in the risk of any breast cancer (invasive or ductal carcinoma in situ [DCIS]) in women with germline BRCA1 mutation who are treated with denosumab compared to placebo. (clinicaltrials.gov)
ARM A: Patients receive denosumab subcutaneously (SC) every 6 months (q6m) for up to 5 years in the absence of the development of breast cancer or unacceptable toxicity. (clinicaltrials.gov)
ARM B: Patients receive placebo SC q6m for up to 5 years in the absence of the development of breast cancer. (clinicaltrials.gov)
We updated our previous report of a phase 2 trial using proton beam radiation therapy to deliver partial breast irradiation (PBI) in patients with early stage breast cancer. (nih.gov)
Purpose: To assess the efficacy and exploratory biomarkers of continuing palbociclib plus endocrine therapy (ET) beyond progression on prior palbociclib-based regimen in patients with hormone receptor-positive/HER2-negative (HR+/HER2−) advanced breast cancer (ABC). (gencat.cat)
Breast cancer that develops during or shortly after pregnancy is frequently more aggressive than cancer diagnosed at other times in a woman's life. (tamu.edu)
To better understand the patterns of cancer-related protein expression in the breasts of lactating women, we determined the differences in total and individual protein expression in milk based on (a) three time points during lactation (early, mid, and late), (b) length of lactation, and (c) parity. (tamu.edu)
8) a neutralizing anti-human GP88 monoclonal antibody (AG1) has been developed in our laboratory and been validated previously in our breast cancer xenograft system. (inknowvation.com)
At the end of this phase I SBIR study, we will have established feasibility studies to develop novel therapies for lung cancer. (inknowvation.com)
Conclusion: T+L did not significantly improve DFS and OS over T alone, both with chemotherapy, and, therefore, cannot be recommended for adjuvant treatment of early-stage HER2-positive breast cancer. (johnshopkins.edu)
for the ALTTO Steering Committee and Investigators 2021, ' Updated results from the international phase III ALTTO trial (BIG 2-06/Alliance N063D) ', European Journal of Cancer , vol. 148, pp. 287-296. (johnshopkins.edu)
Background and purpose: Adjuvant radiotherapy of internal mammary nodes (IMN) improves survival in high-risk early breast cancer patients but inevitably leads to more dose to heart and lung. (regsj.dk)
These estimates are used to guide the choice of selection criteria for the randomised Danish Breast Cancer Group (DBCG) Proton Trial. (regsj.dk)
Materials and methods: 179 breast cancer patients already treated with loco-regional IMN radiotherapy from 18 European departments were included. (regsj.dk)
These estimates are used to guide the choice of selection criteria for the randomised Danish Breast Cancer Group (DBCG) Proton Trial.Materials and methods: 179 breast cancer patients already treated with loco-regional IMN radiotherapy from 18 European departments were included. (regsj.dk)
While research exists on the well-being of women during a specific phase of breast cancer, little research exists in which researchers utilized the same instruments to examine differences in women's well-being, based on the phase of their breast cancer. (elsevierpure.com)
Using a trajectory framework, the purpose of this study is to examine the differences in the physical and social well-being of women during the following breast cancer states: newly diagnosed, adjuvant therapy, stable disease and recurrent disease. (elsevierpure.com)
The convenience sample consisted of 35 women newly diagnosed with breast cancer, 52 women with breast cancer undergoing adjuvant therapy, 84 women whose breast cancer was considered stable and 64 women with recurrent breast cancer. (elsevierpure.com)
Health care professionals need to recognize differences between groups to better meet the needs of patients with a breast cancer diagnosis. (elsevierpure.com)
This trial is testing the safety and efficacy of two immunotherapy drugs in combination with standard chemotherapy to treat metastatic triple negative breast cancer. (withpower.com)
Controversy remains about its impact on the preoperative staging of breast cancer surgery. (bvsalud.org)
This study evaluated survival and surgical outcomes of preoperative MRI in conservative breast cancer surgery. (bvsalud.org)
METHODS: A phase III, randomized, open-label, single-center trial including female breast cancer participants, stage 0-III disease, and eligible for breast-conserving surgery. (bvsalud.org)
We compared the role of including MRI in preoperative evaluation versus radiologic exam routine with mammography and ultrasound in breast cancer conservative candidates. (bvsalud.org)
METHODS: we selected 50 asymptomatic women without a personal or family history of breast cancer, outside the pregnancy and childbirth cycle in order to collect papillary fluid by the automated system. (bvsalud.org)
CIENCIASMEDICASNEWS: (1) American Society of Clinical Oncology clinical practice guideline: update on adjuvant endocrine therapy for women with hormone receptor-positive breast cancer. (blogspot.com)
In 2016, ASCO performed a focused update of the 2014 guideline on adjuvant endocrine therapy based on emerging data concerning the benefits and risks of ovarian suppression in addition to standard adjuvant therapy in premenopausal women with estrogen receptor-positive breast cancer. (blogspot.com)
Cost-effectiveness of 2-[18F]FDG-PET/CT versus CE-CT for response monitoring in patients with metastatic breast cancer: a register-based comparative study. (sdu.dk)
Suppression of Breast Cancer Stem Cells and Tumor Growth by the RUNX1 Transcription Factor. (umassmed.edu)
Antagonizing miR-218-5p attenuates Wnt signaling and reduces metastatic bone disease of triple negative breast cancer cells. (umassmed.edu)
M, Bromberg J. Self-renewal of CD133(hi) cells by IL6/Notch3 signalling regulates endocrine resistance in metastatic breast cancer. (umassmed.edu)
Endocrine therapies are effective in the treatment of hormone receptor (HR)-positive breast cancer, however, de novo or acquired treatment resistance is a significant clinical problem. (elsevierpure.com)
The ENCORE 301 phase II randomized, placebo-controlled study demonstrated a significant improvement in progression-free survival (PFS) and overall survival (OS), with the addition of entinostat to exemestane in patients with HR-positive advanced breast cancer with disease progression after prior non-steroidal aromatase inhibitor (AI). (elsevierpure.com)
These results prompted the development of E2112, a phase III registration trial which is investigating entinostat/placebo in combination with exemestane in patients with locally advanced or metastatic breast cancer who have experienced disease progression after a non-steroidal AI. (elsevierpure.com)
E2112 aims to validate the preclinical and clinical findings supporting the role of HDAC inhibitors in overcoming resistance to endocrine therapy in breast cancer, and ultimately improve outcomes for patients with advanced breast cancer. (elsevierpure.com)
Our aim is to improve prediction models for regional and distant metastatic spread in breast cancer in order to individualise treatment selection for the individual patients. (lu.se)
One prediction model aims to preoperatively identify node-negative breast cancer patients for whom axillary surgery could be abstained. (lu.se)
Chemotherapy comprises part of successful treatment regimens for breast cancer, however, up to 50% of patients develop resistance. (usuhs.edu)
We hypothesize that drug resistance may be associated with stress hormone-induced alterations in breast cancer cells. (usuhs.edu)
It's estimated that every year there are approximately 2,000 new cases of male breast cancer and 400 men will die each year from it. (jimstoppani.com)
This pales in comparison to the roughly 40,000 women who die from breast cancer each year. (jimstoppani.com)
However, the small number of men who are diagnosed with and die from breast cancer is problematic due to the fact that no one is talking about it. (jimstoppani.com)
And because most men would never imagine that they could get breast cancer, they wait far too long to seek the medical attention they need when early symptoms arise. (jimstoppani.com)
These are some of the reasons I'm taking this time to help raise awareness for male breast cancer. (jimstoppani.com)
My goal is to make more men realize that this is a reality and to educate them so that any man who may feel a lump in his chest or any other signs of breast cancer gets the immediate attention he needs. (jimstoppani.com)
Only when more men start talking about breast cancer can others find support from those who have also suffered from it. (jimstoppani.com)
If a man is diagnosed with breast cancer at an early stage, he has a very good chance for survival. (jimstoppani.com)
They're either uninformed that breast cancer is even a possibility or, as I mentioned earlier, are simply embarrassed by it. (jimstoppani.com)
For this reason, many cases of male breast cancer are diagnosed when the disease is more advanced. (jimstoppani.com)
The best thing you can do, in addition to watching yourself for any signs or symptoms, is talk about male breast cancer with your friends. (jimstoppani.com)
Also, if you can, be sure to donate to the National Breast Cancer Foundation ( www.nationalbreastcancer.org ) and the Male Breast Cancer Foundation in Memory of Mr. John W. Nick ( www.malebreastcancer.org ). (jimstoppani.com)
Numerous studies confirm that dairy consumption is associated with a reduced risk of colorectal, breast, bladder, ovarian and prostate cancer. (jimstoppani.com)
BACKGROUND: BRCA1 and BRCA2 genes are critical in homologous recombination DNA repair and have been implicated in familial breast and ovarian cancer tumorigenesis. (ox.ac.uk)
METHODS: This multi-centre phase II single arm trial was designed to investigate the activity and safety of 6-mercaptopurine (6MP) 55 mg/m² per day, and methotrexate 15 mg/m² per week in patients with advanced breast or ovarian cancer, ECOG PS 0-2, progressing after ≥ one prior regimen and known to bear a BRCA1/2 germ line mutation. (ox.ac.uk)
Purpose The mammalian target of rapamycin inhibitor everolimus targets aberrant signaling through the PI3K/AKT/mammalian target of rapamycin pathway, a mechanism of resistance to anti-estrogen therapy in estrogen receptor (ER)-positive breast cancer. (psu.edu)
We hypothesized that everolimus plus the selective ER downregulator fulvestrant would be more efficacious than fulvestrant alone in ER-positive metastatic breast cancer resistant to aromatase inhibitor (AI) therapy. (psu.edu)
Patients and Methods This randomized, double-blind, placebo-controlled, phase II study included 131 postmenopausal women with ER-positive, human epidermal growth factor receptor 2-negative, AI-resistant metastatic breast cancer randomly assigned to fulvestrant (500 mg days 1 and 15 of cycle 1, then day 1 of cycles 2 and beyond) plus everolimus or placebo. (psu.edu)
Conclusion Everolimus enhances the efficacy of fulvestrant in AI-resistant, ER-positive metastatic breast cancer. (psu.edu)
This study is the first to show the safety, tolerability, feasibility, and cosmesis results of a 5-fraction dose-escalated S-PBI treatment for early-stage breast cancer in the adjuvant setting. (elsevierpure.com)
Purpose: This multi-center, randomized, phase III study was conducted to demonstrate the non-inferiority of DA-3031 compared with daily filgrastim in patients during the first cycle of chemotherapy for breast cancer in terms of the duration of severe neutropenia (DSN). (korea.ac.kr)
Methods: Seventy-four patients with breast cancer who were receiving combination chemotherapy with docetaxel, doxorubicin, and cyclophosphamide (TAC) were enrolled. (korea.ac.kr)
Conclusions: DA-3031 and daily filgrastim are similar in regard to DSN and safety in breast cancer patients receiving TAC chemotherapy. (korea.ac.kr)
Here, we investigate the fusion gene landscape in triple-negative breast cancer (TNBC) and high-grade serous ovarian cancer (HGSOC), two subtypes of female cancers with high molecular similarity but limited treatment options at present. (broadinstitute.org)
Sentinel node mapping is rapidly becoming an alternative staging procedure for the axilla in managing early breast cancer . (medscape.com)
Given the high prevalence of breast cancer worldwide, the possibility of avoiding axillary clearance surgery in a significant number of patients makes this an extremely valuable procedure. (medscape.com)
Lymphoscintigraphy is the staging modality of choice for early breast cancer, and breast cancer trials with 5- to 10-year outcome data have shown no significant differences in disease-free survival rates or overall survival rates between lymphoscintigraphy and axial lymph node dissection but have shown significantly lower morbidity with lymphoscintigraphy. (medscape.com)
Participants who have multicentric (the presence of two of more tumor foci within different quadrants of the same breast) and/or multifocal (the presence of two or more tumor foci within a single quadrant of the breast) breast cancer are also eligible if all examined tumors meet pathologic criteria for ER positivity and HER2 negativity â? (who.int)
Participants with bilateral synchronous invasive breast cancer are eligible if all histopathologically examined tumors meet pathologic criteria for ER positivity and HER2 negativity. (who.int)
For cancer, the diagnosis and primary therapy phase of all cancers, as well as colon and rectum cancer with stoma, larynx cancer with laryngectomy and breast cancer with mastectomy, were included (1). (who.int)
Although infectious diseases are stil the major causes of morbidity and mortality, there is some evidence that non communicable diseases like cancer (cervical and breast cancers are reported to be the most common, followed by lung cancer), diabetes mellitus, hypertension, tobacco-related diseases and mental il ness are increasing noticeably. (who.int)
Breast cancer has a worse prognosis when diagnosed during pregnancy or postpartum. (medscape.com)
Methods for early detection are needed, as evidenced every day in the multidisciplinary unit for treating pregnancy-associated breast cancer, which operates within the Breast Unit at the Vall d'Hebron University Hospital in Barcelona, Spain. (medscape.com)
The team working in this field is led by Cristina Saura, PhD, who is also head of the Breast Cancer Group at the Vall d'Hebron Institute of Oncology (VHIO). (medscape.com)
The results of a study recently published in Cancer Discovery show, for the first time, that breast milk from breast cancer patients contains circulating tumor DNA (ctDNA) that can be detected by a liquid biopsy of the milk. (medscape.com)
In this case, it arose from the concerns of a breast cancer patient who was diagnosed while pregnant with her third daughter. (medscape.com)
She had been breastfeeding for a long time and had stretched it out until shortly before she was diagnosed with breast cancer. (medscape.com)
Though we knew that breast cancer is not transmitted through breast milk, we decided to test the sample and look for markers that could help our research. (medscape.com)
She noted that the breast milk they analyzed had been frozen for more than a year before the patient's cancer diagnosis. (medscape.com)
In terms of methodology, Ana Vivancos, PhD, head of the VHIO Cancer Genomics Group and also one of the authors of the study, explained that they used two techniques to analyze the breast milk and blood samples: next-generation sequencing and droplet digital polymerase chain reaction. (medscape.com)
We were able to detect tumor mutations in milk samples from 13 of the 15 patients with breast cancer who were tested, while circulating tumor DNA was detected in only one of all the blood samples that were collected at the same time," said Vivancos. (medscape.com)
As a next step to make this finding practically useful, the research team designed a genomic panel using next-generation sequencing as a potential method for early detection of breast cancer. (medscape.com)
The panel has been calibrated, based on the existing literature, to detect the genes that are most frequently mutated in breast cancer in young women under 45 years old. (medscape.com)
In practice, the panel design allows us to detect mutations in more than 95% of breast cancer cases in women under 45 years old. (medscape.com)
That's exactly the goal of this research: to screen for breast cancer in women who have just given birth. (medscape.com)
In Saura's opinion, in Spain, just like taking a small blood sample from newborns in a heel-prick test to rule out metabolic diseases, milk samples could be taken from women who give birth to rule out or diagnose breast cancer. (medscape.com)
Chemoprevention is an appealing strategy with proven success in familial adenomatous polyposis (FAP) and breast cancer. (medscape.com)
Delores is a 62-year-old elementary school teacher and a breast cancer survivor. (medscape.com)
She was diagnosed with stage IIB, estrogen -receptor (ER)-positive and progesterone-receptor (PR)-positive, HER2-n egative breast cancer and was treated with mastectomy and chemotherapy. (medscape.com)
As during previous visits, she expresses her high anxiety about the possibility of recurrence of her disease, and her anxiety has worsened since the recent death of her sister from breast cancer. (medscape.com)
Cancers such as doxorubicin are commonly used in cancer leukaemia, colorectal, breast, lung, and so on are chemotherapy. (who.int)
Carcinoma1
Lymphoscintigraphy is indicated for proven palpable or nonpalpable invasive breastcarcinoma for which removal of the primary tumor and axillary node dissection would be indicated. (medscape.com)
Malignant9
80% of neoplasms are benign, although their tendency to recur or develop into malignant tumors varies. (medtigo.com)
The equitable distribution of benign and malignant neoplasms makes up 10 to 15% of all salivary gland tumors in the submandibular gland. (medtigo.com)
Epithelioid angiosarcoma is a rare malignant neoplasm found in vascular endothelial cells. (bvsalud.org)
Angiosarcoma is a rare malignant vascular neoplasm which constitutes less than 1% of all sarcomas. (bvsalud.org)
Epithelioid angiosarcoma (EA) is a rare variant of angiosarcoma, which is characterized by a high-grade malignant neoplasm, which consists of an atypical, multilayered, or solid endothelial proliferation and vasoformative architecture, presenting necrosis and an area of hemorrhage 1-5 . (bvsalud.org)
Neoplasms that arise in the salivary glands are relatively rare, yet they represent a wide variety of both benign and malignant histologic subtypes as seen in the image below. (medscape.com)
Benign neoplasms occur more frequently in women than in men, but malignant tumors are distributed equally between the sexes. (medscape.com)
Almost half of all submandibular gland neoplasms and most sublingual and minor salivary gland tumors are malignant. (medscape.com)
As to the potential advantages that breast milk liquid biopsy could have over similar techniques like blood liquid biopsy, Vivancos pointed to the results of her study: "We have seen that breast milk liquid biopsy was positive for the presence of circulating tumor DNA in 87% of cases, whereas blood only revealed the presence of this marker in 8% of cases. (medscape.com)
Genes2
Transcriptome analysis reveals overlap in fusion genes in a phase I clinical cohort of TNBC and HGSOC patients treated with buparlisib and olaparib. (broadinstitute.org)
RNA-seq was utilized to identify fusion genes in a cohort of 18 TNBC and HGSOC patients treated with the PI3K inhibitor buparlisib and the PARP inhibitor olaparib in a phase I clinical trial (NCT01623349). (broadinstitute.org)
Mutation4
A germline mutation is an inherited gene change which, in the BRCA1 gene, is associated with an increased risk of breast and other cancers. (clinicaltrials.gov)
To determine the reduction in risk of other (i.e. non-breast and nonovarian) malignancies, including those known to be associated with BRCA1 germline mutations in women with germline BRCA1 mutation who are treated with denosumab compared to placebo. (clinicaltrials.gov)
To compare rates of breast biopsies and rate of benign breast lesions in women with germline BRCA1 mutation who are treated with denosumab compared to placebo. (clinicaltrials.gov)
In the end, when we analyzed the patient's breast milk, we found DNA with the same mutation that was present in her tumor," explained Saura. (medscape.com)
Survival2
Administration of trilaciclib prior to gemcitabine plus carboplatin (GCb) significantly improved overall survival (OS) compared with GCb alone in an open-label phase II trial in patients with metastatic TNBC, potentially through protection and direct activation of immune function. (duke.edu)
Proton beam radiation therapy for PBI produced excellent ipsilateral breast recurrence-free survival with minimal toxicity. (nih.gov)
Cell proliferation1
P21 (CDKN1A), a key cell cycle regulatory protein that governs cell cycle progression from G1 to S phase, can regulate cell proliferation, growth arrest, and apoptosis. (duke.edu)
Invasive1
BACKGROUND: Breast magnetic resonance imaging (MRI) has high sensitivity in detecting invasive neoplasms. (bvsalud.org)
MeSH1
Neoplasm Transplantation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
Most series report that about 80% of parotid neoplasms are benign, with the relative proportion of malignancy increasing in the smaller glands. (medscape.com)
Submandibular2
Among salivary gland neoplasms, 80% arise in the parotid glands, 10-15% arise in the submandibular glands, and the remainder arise in the sublingual and minor salivary glands. (medscape.com)
A phase II clinical trial of 6-mercaptopurine (6MP) and methotrexate in patients with BRCA defective tumours: a study protocol. (ox.ac.uk)
Tumor5
Both procedures showed that tumor cells were capable of moving through S phase even in the presence of an apparently near complete inhibition of deoxyuridine incorporation into DNA. (elsevierpure.com)
18 F]PARPi was evaluated in vivo in breast and prostate xenograft tumor models by microPET imaging, biodistribution and autoradiography. (wustl.edu)
Participants must have undergone definitive surgery of the primary breast tumor(s). (who.int)
She was worried that she had transmitted the tumor through her breast milk to her second daughter while breastfeeding. (medscape.com)
The most common tumor of the parotid gland is the pleomorphic adenoma , which represents about 60% of all parotid neoplasms, as seen in the image below. (medscape.com)
Adjuvant2
National Surgical Adjuvant Breast and Bowel Project (NSABP) B-38 had a proportion of 18.8% of cases 'not meeting' the receptor status subcategory criterion. (nih.gov)
Women with stage II or stage III breast cancers who would ordinarily be advised to receive adjuvant chemotherapy should receive ovarian suppression in addition to endocrine therapy. (blogspot.com)
Mortality2
In 2005, cardiovascular diseases, neoplasms, malaria, respiratory diseases and neonatal causes were major public health problems in terms of mortality. (who.int)
A reduction in childhood mortality and morbidity from diarrhoeal diseases is attributed to the improved status of sanitation, water supply, personal hygiene and breast-feeding. (who.int)
Cancers1
Women with stage I or II breast cancers at higher risk of recurrence, who might consider chemotherapy, may also be offered ovarian suppression in addition to endocrine therapy. (blogspot.com)
Tumors4
Age-specific differences in oncogenic pathway deregulation seen in human breast tumors. (duke.edu)
As for this unresolved need, Saura explained that there is currently no system or tool available to allow early suspicion of breast tumors in pregnant women prior to diagnosis. (medscape.com)
Although researchers have learned much from the study of this diverse group of tumors over the years, the diagnosis and treatment of salivary gland neoplasms remain complex and challenging problems for the head and neck surgeon. (medscape.com)
The randomized, double-blind, placebo-controlled, phase III PRESERVE 2 trial will evaluate the efficacy and safety of trilaciclib administered prior to GCb in patients with locally advanced unresectable or metastatic TNBC. (duke.edu)
Parity1
We recorded and related to the production of papillary fluid patient age, smoking habit, previous breast surgery, parity, breastfeeding, menopausal status and age at menarche. (bvsalud.org)
Diagnosis1
The diagnosis of myeloproliferative neoplasm (MPN), The diagnosis of myeloproliferative neoplasm (MPN), unclassifiable, requires that either all 3 criteria are met. (who.int)
Abstract1
abstract = "Introduction: Solid-phase synthesis and conjugation reactions of acids and amines using coupling reagents are common in organic synthesis, but rare in 18F radiochemistry. (wustl.edu)
Immunohistochemical analysis that demonstrates the endothelial nature of the neoplasm is frequently positive for specific vascular markers (CD31, CD34, factor VIII), and keratin 1,2,5,6 . (bvsalud.org)
Pregnancy1
The medical history records the woman's age, the number of children she has borne, her breast-feeding practices, plans for pregnancy and nursing of the infant, medication allergies, and tendency to bleeding. (wikipedia.org)
Women1
Patients and Methods: The multicenter, open-label, phase II BioPER trial included women who had experienced a progressive disease (PD) after having achieved clinical benefit on the immediately prior palbociclib plus ET regimen. (gencat.cat)
Bilateral1
Macromastia can be manifested either as a unilateral condition or as a bilateral condition (single-breasted enlargement or double-breasted enlargement) that can occur in combination with sagging, breast ptosis that is determined by the degree to which the nipple has descended below the inframammary fold (IMF). (wikipedia.org)
Recurrent breast1
Nonetheless, it is statistically rare for a young woman to experience virginal mammary hypertrophy that results in massive, oversized breasts, and recurrent breast hypertrophy. (wikipedia.org)