Therefore, it is critically important that we gain a greater understanding of the effects and risks of cannabinoid use on cardiovascular diseases as well as the potential for cannabinoid-directed drugs to be used as therapeutics for the treatment of cardiovascular disease. (aspetjournals.org)
Significance Statement Cardiovascular diseases including atherosclerosis and myocardial infarction are a leading cause of death. (aspetjournals.org)
The aims of this unit are to provide a knowledge base of recent developments in understanding the cardiovascular system and its role in human diseases, and to examine how such understanding can lead to identification and exploitation of novel drug targets for future therapy. (bath.ac.uk)
To be able to discover novel drug targets we aim to develop software based on network theoretic approaches that are capable to identify mediators and pathways involved in the pathomechanism of various cardiovascular diseases by the analysis of datasets assessed with high throughput molecular biological techniques (e.g. microarray, RNA-seq) of samples gathered from small and large animal models of the studied cardiovascular disorders. (semmelweis.hu)
In this project we aim to develop, implement and utilize such network theoretic models to efficiently search for drug target candidates in various cardiovascular diseases. (semmelweis.hu)
Hossein Ardehali, MD, PhD, is working to understand the role of iron and metabolic processes in cardiovascular disease and develop new therapies that target iron accumulation in people with CVD and many other chronic diseases. (northwestern.edu)
W e 're hoping that our studies (with iron chelators and cardiovascular disease) in the preclinical phase , will guide us to translate those into clinical practice and treating patients with various chronic diseases. (northwestern.edu)
Investigation must be related to cardiovascular diseases and can be basic, clinical, translational, epidemiologic or public health-related, and includes stroke. (uvm.edu)
Research Interests: understanding how stress, obesity and aging affect neuroendocrine regulation of blood pressure with an aim to identify novel therapeutic targets for the treatment of hypertension and cardiovascular diseases. (uvm.edu)
3 Hypertension puts the elderly at greater risk for developing several cardiovascular diseases (CVDs), ranging from myocardial infarction, angina, and cerebrovascular disease to peripheral artery disease and cardiac failure. (uspharmacist.com)
The goal of pharmacology is to develop and study drugs used to combat human diseases. (lu.se)
Physiology2
Research interests include vascular pharmacology and physiology, structure and mechanics of the circulation and haemodynamics in relation to vascular disease. (imperial.ac.uk)
Internationally renowned visitors showcase cutting-edge research in physiology, pharmacology, and related disciplines, spanning basic research to translational science. (uc.edu)
Drugs11
Cannabinoid drugs have well-known acute effects on cardiovascular function including tachycardia and orthostatic hypotension. (aspetjournals.org)
Pharmacology is the study of drugs and their effects on living organisms. (uea.ac.uk)
Pharmacology is the study of how drugs and other chemicals affect the body in health and disease. (strath.ac.uk)
Pharmacology is the science of the effects of drugs on biological systems, from the molecular level through to patient studies. (otago.ac.nz)
Pharmacology and Toxicology are at the forefront of modern medicine with a focus on developing drugs to treat important conditions, such as cancer, diabetes, neurological conditions and heart disease. (otago.ac.nz)
Most people are interested in pharmacology because drugs occupy such a prominent place in everyday life. (otago.ac.nz)
Constant progress in medicine involves the design of new drugs that can cure cancer, cardiovascular disease, neurological disorders and other medical conditions. (otago.ac.nz)
Unlike pharmacy, which is about the preparation and dispensing of drugs, pharmacology is the science behind how drugs produce their effects on the body and what the body does to the drugs. (otago.ac.nz)
Pharmacology also plays a key role in developing drugs of the future. (otago.ac.nz)
Pharmacokinetics of cardiovascular, central nervous system, and antimicrobial drugs / Peter G. Welling, Francis L. S. Tse. (who.int)
Examples of topics that may be included are: endocrine pharmacology, psychoactive drugs, asthma therapy, cardiovascular pharmacology and drug delivery. (lu.se)
A good knowledge of pharmacology and toxicology is also an important part of the training of medical doctors, pharmacists, dentists, nurses and physiotherapists. (otago.ac.nz)
Pharmacology and Toxicology are also popular choices for students seeking a career in the professional medical sciences (e.g. (otago.ac.nz)
A series of nine papers was recently published as a special issue in Toxicology and Applied Pharmacology to help better understand the physico-chemical characteristics of FSDs and compare the biological effects of FSDs to pure crystalline silica in an animal model. (cdc.gov)
The new special issue of Toxicology and Applied Pharmacology, Biological Effects of Inhaled Hydraulic Fracturing Sand Dust , is an initial step in this direction. (cdc.gov)
Epidemiology1
Research Interests: cardiovascular disease epidemiology and the practical application of technology for the prevention of chronic disease. (uvm.edu)
Pharmacy2
You'll study in the internationally renowned School of Pharmacy, which conducts world-class research in areas such as cancer, cardiovascular disease, antibiotic resistance and tissue engineering. (uea.ac.uk)
PharmD From University of California San Francisco, PGY-1 Pharmacy Practice residency at Washington Hospital Center, PhD and Post Doc in Pharmacology and Biophysics from Georgetown University. (su.edu)
Disease13
Cardiovascular disease represents a leading cause of death, morbidity, and societal economic burden. (aspetjournals.org)
This narrative review on the role of cannabinoid signaling in cardiovascular disease contributes to a better understanding of this topic by integrating current knowledge and identifying critical gaps. (aspetjournals.org)
Impressive evidence exists for the use of bupropion in smoking cessation among difficult patients who are hard-core smokers such as those with cardiovascular disease, chronic obstructive pulmonary disease (COPD) and depression. (nih.gov)
Objectives Studies on the health effects of aircraft and road traffic noise exposure suggest excess risks of hypertension, cardiovascular disease and the use of sedatives and hypnotics. (bmj.com)
He was consultant physician at St Mary's & Hammersmith hospitals and co-director of the Peart-Rose hypertension & cardiovascular disease prevention clinic. (imperial.ac.uk)
Clinical interests include general medicine, hypertension, cardiovascular disease prevention and hypertensive complications of pregnancy. (imperial.ac.uk)
Cardiovascular disease (CVD) is the number one cause of death globally, and nearly half of all U.S. adults are currently at risk for heart attack and stroke. (northwestern.edu)
In recent years cardiovascular disease has been the number one cause of death in the world. (northwestern.edu)
This trend to cardiovascular disease (CVD) claiming the most lives every year was one reason why Ardehali became interested in CVD research and finding new treatments for CVD. (northwestern.edu)
Cardiovascular disease is the number one cause of death worldwide. (northwestern.edu)
Today's guest, Dr. Hossein Ardehali, is focused on the role of metabolic processes and cardiovascular disease. (northwestern.edu)
Prevalence of Diabetes and Its Association with Atherosclerotic Cardiovascular Disease Risk in Patients with Familial Hypercholesterolemia: An Analysis from the Hellenic Familial Hypercholesterolemia Registry (HELLAS-FH). (cdc.gov)
Effects of the ABCB1 C3435T single nucleotide polymorphism on major adverse cardiovascular events in acute coronary syndrome or coronary artery disease patients undergoing percutaneous coronary intervention and treated with clopidogrel: A systematic review and meta-analysis. (cdc.gov)
Hypertension1
He was a member of the executive committee of the British Hypertension Society, the national hypertension guidelines group and the cardiovascular NIHR specialty group. (imperial.ac.uk)
Clinical3
Simon Thom is emeritus professor of cardiovascular medicine & clinical pharmacology at Imperial College London. (imperial.ac.uk)
He trained at St Mary's Hospital Medical School and subsequently in hospital posts in Bath and Newcastle-upon-Tyne before returning to Peter Sever's department of clinical pharmacology at St Mary's (now Imperial College London) over 40 years ago. (imperial.ac.uk)
As shown below, the program includes three special events: the Kranias Symposium on Early Career Mentorship, PSP Trainees' Research Day, and the Arnold Schwartz Cardiovascular Clinical Pharmacology Lecture. (uc.edu)
Acute1
Learn about Cardiovascular Imaging with these comprehensive activities covering key topics such as lung conditions and acute chest conditions all while earning CME credits. (cmelist.com)
For example, in practical classes you'll gain experience of synthetic medicinal chemistry as well as techniques in current molecular pharmacology - the techniques used in the discovery of new medicines. (uea.ac.uk)
The PharmacologyDrug Discovery programme is the only MSci of its type in the UK and is innovative in its multidisciplinary approach. (uea.ac.uk)
Department3
Each year the Department of Pharmacology invites distinguished researchers to present their work on topics broadly related to pharmacology. (ucdavis.edu)
2007-2010: Tenure-track Independent Research Fellow in Cardiovascular Medicine, Department of BIological Sciences, University of Leeds, Leeds, UK. (abdn.ac.uk)
Metabolism1
Cyclic AMP (cAMP) and cGMP regulate a myriad of cellular functions, such as metabolism, contractility, motility, and transcription in virtually all cell types, including those of the cardiovascular system. (aspetjournals.org)
System4
More recently, a central role for cyclic nucleotide phosphodiesterase (PDE) has also been elaborated in many cell types, including those involved in regulating the activities of the cardiovascular system. (aspetjournals.org)
In this review, we introduce the PDE families whose members are expressed in cells of the cardiovascular system including cardiomyocytes, vascular smooth muscle cells, and vascular endothelial cells. (aspetjournals.org)
On successful completion of this unit, the student should be able to: synthesise an in-depth knowledge of recently identified target molecules and processes in the cardiovascular system, evaluate critically the role of these targets in particular therapeutic areas and utilise a range of ICT and cognitive skills in acquiring knowledge and understanding and applying them to complex, incomplete or contradictory situations. (bath.ac.uk)
Thought you might appreciate this item(s) I saw in Journal of Cardiovascular Pharmacology. (lww.com)
Respiratory2
Because there is little to no information about FSD potential toxicity, NIOSH researchers designed a comprehensive hazard identification study using a rat animal model study to investigate the early adverse effects of several FSDs on organ functions (looking at respiratory, cardiovascular, immune systems, kidneys, and brain), in comparison to MIN-U-SIL ® 5, a respirable α-quartz dust (crystalline silica) that was used as a reference. (cdc.gov)
FSD 8 was examined more thoroughly, in other parts of the body, including the respiratory, cardiovascular and immune systems, brain and kidney. (cdc.gov)
Biochemistry1
In Year 2, you'll gain an introduction to each of the four disciplines: Biochemistry, Immunology, Microbiology and Pharmacology again supported by the Being a Biomolecular Scientist module which develops various skills gained in Year 1. (strath.ac.uk)
Disorders1
Nonadherence is estimated to result in 125,000 deaths due to cardiovascular disorders each year in the US. (msdmanuals.com)
Chronic1
The major objective of this study was to investigate the anti-chronic nonbacterial prostatitis (CNP) mechanism of T. patula by metabolomics and network pharmacology. (mdpi.com)
Effects2
Safety pharmacology is the evaluation and study of the pharmacological effects of a potential drug that are unrelated to the desired therapeutic effect. (routledge.com)
Cardiovascular effects of marijuana. (bvsalud.org)
Research5
This narrative review serves to summarize current research on the role of cannabinoid signaling in cardiovascular function with the goal of identifying critical knowledge gaps and future studies to address those gaps in a way that facilitates the development of new treatments and better cardiovascular health. (aspetjournals.org)
Our research-rich environment is pivotal to the Pharmacology and Drug Discovery course, which has been designed to prepare you for a career at the forefront of pharmaceutical research. (uea.ac.uk)
You'll be taught by academic researchers including pharmacologists, cell biologists, and medicinal and pharmaceutical chemists, whose own research is in pharmacology and drug discovery. (uea.ac.uk)
In July 2017, Martin E. Bloomfield, MD '60 and Judith S. Bloomfield '59 endowed the Bloomfield Early Career Professorship in Cardiovascular Research within the CVRI to encourage and support early-stage, independent investigators in developing high quality and competitive cardiovascular research programs. (uvm.edu)
Sciences1
The pharmacology course will be a very valuable basis for further postgraduate studies or for future work within the fields of biomedicine and pharmaceutical sciences. (lu.se)