The first benzo to be developed was chlordiazepoxide, known as Librium, and was discovered by accident after co-workers noticed there was a "beautiful crystalline" structure leftover during tests for new tranquilizers. (landmarkrecovery.com)
The anti-anxiety drug chlordiazepoxide, aka Librium, was the first in the class of 1,4-benzodiazepines, and it was also synthesised accidentally. (chemistryworld.com)
Advertisement for Librium (chlordiazepoxide HCI), a medication manufactured by Roche Laboratories to reduce anxiety. (omeka.net)
Hydrochloride20
Chlordiazepoxide Hydrochloride and Clidinium Bromide (Heritage Pharmaceuticals. (medlibrary.org)
Chlordiazepoxide hydrochloride and clidinium bromide capsules may produce physical dependence from continued therapy. (medlibrary.org)
Tolerance to chlordiazepoxide hydrochloride and clidinium bromide capsules may develop from continued therapy. (medlibrary.org)
Because of the varied individual responses to tranquilizers and anticholinergics, the optimum dosage of chlordiazepoxide hydrochloride and clidinium bromide capsules varies with the diagnosis and response of the individual patient. (medlibrary.org)
The initial dose should not exceed 2 chlordiazepoxide hydrochloride and clidinium bromide capsules per day, to be increased gradually as needed and tolerated. (medlibrary.org)
Chlordiazepoxide hydrochloride and clidinium bromide capsules are available in light green opaque capsules, each containing 5 mg chlordiazepoxide hydrochloride and 2.5 mg clidinium bromide in bottles of 100 capsules (NDC 23155-808-01), with "VP302" imprinted on the cap of the capsule. (medlibrary.org)
The use of benzodiazepines, including chlodiazepoxide hydrochloride, a component of Chlordiazepoxide Hydrochloride and Clidinium Bromide Capsules, exposes users to risks of abuse, misuse, and addiction, which can lead to overdose or death. (nih.gov)
Before prescribing Chlordiazepoxide Hydrochloride and Clidinium Bromide Capsules and throughout treatment, assess each patient's risk for abuse, misuse, and addiction (see WARNINGS ). (nih.gov)
The continued use of benzodiazepines, including Chlordiazepoxide Hydrochloride and Clidinium Bromide Capsules, may lead to clinically significant physical dependence. (nih.gov)
Abrupt discontinuation or rapid dosage reduction of Chlordiazepoxide Hydrochloride and Clidinium Bromide Capsules after continued use may precipitate acute withdrawal reactions, which can be life-threatening. (nih.gov)
Chlordiazepoxide Hydrochloride and Clidinium Bromide Capsules is a fixed-combination of chlordiazepoxide hydrochloride, a benzodiazepine, and clidinium bromide, an anticholinergic. (nih.gov)
Each Chlordiazepoxide Hydrochloride and Clidinium Bromide capsule contains the active ingredients 5 mg chlordiazepoxide hydrochloride and 2.5 mg clidinium bromide. (nih.gov)
Chlordiazepoxide hydrochloride is 7-chloro-2-methylamino-5-phenyl-3H-1,4-benzodiazepine 4-oxide hydrochloride. (nih.gov)
Chlordiazepoxide hydrochloride has been studied extensively in many species of animals and these studies are suggestive of action on the limbic system of the brain, which recent evidence indicates is involved in emotional responses. (nih.gov)
The taming effect of chlordiazepoxide hydrochloride was further demonstrated in rats made vicious by lesions in the septal area of the brain. (nih.gov)
The oral LD 50 of single doses of chlordiazepoxide hydrochloride, calculated according to the method of Miller and Tainter, is 720 ± 51 mg/kg as determined in mice observed over a period of 5 days following dosage. (nih.gov)
Pill with imprint 958 par is Green & Yellow, Capsule-shape and has been identified as Chlordiazepoxide Hydrochloride 5 mg. (drugs.com)
A simple, accurate, precise, rapid, economical and sensitive UV spectrophotometric method has been developed for the determination of trifluoperazine Hydrochloride in pharmaceutical preparations and environmental wastewater samples, which shows maximum absorbance at 257 nm in distilled water. (rroij.com)
No interference was observed from common excipients and additives often accompany with trifluoperazine Hydrochloride in pharmaceutical preparations .The method was successfully applied to the determination of trifluoperazine Hydrochloride in some pharmaceutical formulations (tablets) and industrial wastewater samples. (rroij.com)
Besides him, the list (according to A.41) were included: tablets, and (or) a capsule containing either dosage of one of the following substances: phentermine, chlordiazepoxide, fenfluramine, amfepramone, alpramazol, phenylpropanolamine, hlordiazepoksidin, in combination with other drugs pharmacologically active agents (sometimes referred to as a generalized named 'Thai tablets') used for exchange program weight correction. (magisglobal.com)
Benzodiazepine4
It was the first benzodiazepine to be synthesized and the discovery of chlordiazepoxide was by pure chance. (wikipedia.org)
In tests of various benzodiazepine compounds, chlordiazepoxide was found to cause the most profound reduction in the turnover of 5HT (serotonin) in rats. (wikipedia.org)
Chronic use of benzodiazepines, such as chlordiazepoxide, leads to the development of tolerance, with a decrease in number of benzodiazepine binding sites in mice forebrains. (wikipedia.org)
Advertisement for Miltown (meprobamate), manufactured by Wallace Pharmaceuticals. (omeka.net)
Benzodiazepines4
Chlordiazepoxide and other benzodiazepines were initially accepted with widespread public approval but were followed with widespread public disapproval and recommendations for more restrictive medical guidelines for its use. (wikipedia.org)
Serotonin is closely involved in regulating mood and may be one of the causes of feelings of depression in rats using chlordiazepoxide or other benzodiazepines. (wikipedia.org)
Benzodiazepines were developed in the 1950's in New Jersey, specifically in 1957 by chemists working for Hoffman La Roche, a Swiss pharmaceutical and healthcare multinational. (landmarkrecovery.com)
Diazepam1
Increased fat increases the volume of distribution for highly lipophilic drugs (eg, diazepam, chlordiazepoxide) and may meaningfully increase their elimination half-lives. (msdmanuals.com)
Capsule2
It is supplied by Granules Pharmaceuticals Inc. Cipla 422 100 mg Pill - white capsule/oblong, 18mm. (bistropizzacasa.de)
It is supplied by Ranbaxy Pharmaceuticals Inc. 142 Pill - white capsule/oblong. (bistropizzacasa.de)
The company is into manufacturing and exporting of Pharmaceutical Products under almost all dosage forms and categories consisting more than 380 products. (tradeindia.com)
With the prescription copy or physician's certificate, allowable number could be from 6 to 9 original packages of medicinal product of the same name, pharmaceutical form, strength and dosage number. (palanga-airport.lt)
Therapeutic2
So, oral controlled release and site-specific drug delivery system has been of great interest in the pharmaceutical field to achieve an improved therapeutic advantage. (ijpsr.com)
With increasing regulatory strictness, the quality, quantity and safety of imipramine can be maintained for obtaining optimum therapeutic concentration and for quality assurance in pharmaceutical formulations. (openaccesspub.org)
Pregnancy1
If chlordiazepoxide is used during pregnancy the risks can be reduced via using the lowest effective dose and for the shortest time possible. (wikipedia.org)
India1
SALVAVIDAS PHARMACEUTICAL PVT LTD is a reputed and fast growing Manufacturing Company in Pharmaceutical & Healthcare Industry for over a decade, based in Surat, Gujarat, India. (tradeindia.com)
Applicable for the pharmaceutical industry, Pharmaceutical Pellets can be defined as the little, free-flowing, spherical particulate matters produced by the accumulation of grains of drug substances or fine powders and excipients, by utilizing the most appropriate processing equipments. (jairadhesales.co.in)
Active6
Chlordiazepoxide has a medium to long half-life but its active metabolite has a very long half-life. (wikipedia.org)
Thus there is need for the development of new, simple, sensitive and accurate analytical method for the quantitative estimation of trifluoperazine as an active pharmaceutical ingredient . (rroij.com)
The importance of analytical techniques involved in the quality control analysis of active drug in pharmaceutical formulations has been discussed in published papers 4 , 5 , 6 . (openaccesspub.org)
Imipramine HCl is weakly fluorescent in nature and reagents such as erythrosine B in chloroform 20 and rhodamine B in ethylene glycol-distilled water medium 21 have been utilized for quantitative determination of active drug in pharmaceutical formulations by fluorescence spectrophotometry. (openaccesspub.org)
We are offering best quality Active Pharmaceutical Ingredients, which suffice as the biologically active pharmaceutical medicates. (jairadhesales.co.in)
The following status describes submitted unfinished drugs, including the marketing categories of Active Pharmaceutical Ingredient (API), Drug for Further Processing, Bulk for Human Drug Compounding, and Bulk for Animal Drug Compounding. (hipaaspace.com)
Medication1
Barbiturates were developed by German pharmaceutical companies in the early 20th century and became a popular over-the-counter medication during the Great Depression in the United States. (landmarkrecovery.com)
DRUG3
Pharmaceutical or a drug is classified on the basis of their origin. (lessonotes.com)
In Ethiopia, the Food, Medicine and Health Care Administration and Authority (FMHACA), formerly known as the Drug Administration and Control Authority, regulates the country's pharmaceutical sector in an environment vulnerable to drug smuggling and the circulation of substandard medicines. (rwmansiononpeachtree.com)
IMF is pharmacologically similar to pharmaceutical fentanyl (PF), but is unlawfully produced in clandestine laboratories, obtained via illicit drug markets, and includes fentanyl analogs. (cdc.gov)
Drugs3
Sedative drugs and sleeping pills, including chlordiazepoxide, have been associated with an increased risk of death. (wikipedia.org)
One of our specializations is Contract Manufacturing and 3rd Party Manufacturing where we ensure we manufacture the required pharmaceutical drugs and make it easily accessible to the market. (tradeindia.com)
The pharmaceutical industry makes heavy use of high-throughput screening for lead compounds, so in a sense many drugs are discovered by randomly searching for a needle in a haystack. (chemistryworld.com)
Trifluoperazine1
All chemical used were of analytical or pharmaceutical grade and trifluoperazine standard material was provided from AL-hokamaa company for pharmaceutical industries (HPI) Mosul-Iraq. (rroij.com)
Laboratories1
Produced by: SEDICO Pharmaceutical Co. Under Licence of: Riom Laboratories - France. (farmastan.com)
Liver1
Common side-effects of chlordiazepoxide include: Confusion Constipation Drowsiness Fainting Altered sex drive Liver problems Lack of muscle coordination Minor menstrual irregularities Nausea Skin rash or eruptions Swelling due to fluid retention Yellow eyes and skin Chlordiazepoxide in laboratory mice studies impairs latent learning. (wikipedia.org)
Industries1
Store below 30 degrees C.* Produced by: Chemipharm Pharmaceutical Industries S.A.E. - Egypt. (farmastan.com)
Product2
Store between 15 degrees - 30 degrees C.* Product of: Amoun Pharmaceutical Co. S.A.E. - Egypt. (farmastan.com)
Store in a cool dry place, up to 30 degrees C. * Product of: AlfaCure Pharmaceuticals Co. s.a.e. (farmastan.com)
Treatment1
Chlordiazepoxide is indicated for the short-term (2-4 weeks) treatment of anxiety that is severe and disabling or subjecting the person to unacceptable distress. (wikipedia.org)
Journal1
Journal of Advanced Pharmaceutical Science And Technology - 1(3):29-47. (openaccesspub.org)
Resources1
We have the expertise, flexibility, and resources to provide a full range of pharmaceutical API custom development services at every stage of the lifecycle. (cambrexprofarmaco.com)
Professional1
At the present time would be considered professional cases against members of pharmaceutical institutions in st.234 cc - 'illegal turnover potent substances. (magisglobal.com)