Horseradish PeroxidaseHeme peroxidasesThyroid peroxidase antibodiesAntibodies against thyroid peroxidaseAntibodyHydrogenGlutathione and glutathioneEnzyme glutathioneAscorbate peroxidaseGpx4SubstrateProteinsCytochromeOxidationExtracellularSelenoproteinProteinNeutrophilMoleculeActivityGeneRegulationImmuneGenesReactionSensitivityProcedureCatalyzeDetection systemsContentMeSHSystemFamilyRoleCellsActivitiesShows
Horseradish Peroxidase6
- Certain 6-hydroxybenzothiazole and phenol derivatives enhance light emission from the horseradish peroxidase catalysed oxidation of cyclic diacyl hydrazides such as luminol. (bham.ac.uk)
- These reactions produce novel, enhanced chemiluminescent assays for horseradish peroxidase labels used in immunoassays. (bham.ac.uk)
- The utility of enhanced chemiluminescent assays for horseradish peroxidase conjugates was demonstrated in a range of immunoassays, both immunoextraction and competitive, in conjunction with a variety of solid supports such as plastic beads, tubes and microtitre plates. (bham.ac.uk)
- This research investigated the applicability of a luminol-based chemiluminescence assay to monitor transport of horseradish peroxidase (HRP) enzyme in saturated porous media. (k-state.edu)
- Horseradish Peroxidase Conjugated Antibody, supplied by OriGene, used in various techniques. (bioz.com)
- Goat Anti Mouse Igg Horseradish Peroxidase Conjugate, supplied by OriGene, used in various techniques. (bioz.com)
Heme peroxidases3
- Based on sequence alignments, heme peroxidases have been divided into three classes. (rcsb.org)
- Collectively, the data show that all three members of the class I heme peroxidases can support radical formation on the distal tryptophan and that the reactivity of this radical can be controlled either by the protein structure or by the nature of the compound I intermediate. (bris.ac.uk)
- Protonation of the proximal histidine ligand in heme peroxidases. (lu.se)
Thyroid peroxidase antibodies5
- What Are Thyroid Peroxidase Antibodies? (kidshealth.org)
- Why Are Thyroid Peroxidase Antibodies Tests Done? (kidshealth.org)
- If you have questions about the thyroid peroxidase antibodies test or what the results of the test mean, talk to your doctor. (kidshealth.org)
- Women with glomerulonephritis had both a significantly greater prevalence of thyroid peroxidase antibodies (odds ratio 3.85, 95% confidence interval 1.04-14.3) and an increased prevalence of elevated serum TSH values (P = 0.007). (lu.se)
- The Thyroid Profile consists of a battery of several tests for the measurement of thyroid function, including Total and Free Thyroxine, Total and Free Triiodothyronine, Thyroglobulin, Thyroglobulin Antibodies, Thyroid Peroxidase Antibodies, and Thyroid Stimulating Hormone. (cdc.gov)
Antibodies against thyroid peroxidase2
- Usually, the immune system doesn't make a lot of antibodies against thyroid peroxidase because it's not a germ. (kidshealth.org)
- positive titers of antibodies against thyroid peroxidase was the main underlying abnormality found in 16 out of 27 (59.2%) of patients with DEMS/SAPS compared to 11 out of 54 (20.4%) of pSS controls (p = 0.0009). (vitality101.com)
Antibody3
- The thyroid peroxidase antibody test measures these antibodies in the blood. (medlineplus.gov)
- Thyroid peroxidase (TPO, antimicrosomal antibody, antithyroid microsomal antibody) antibody - blood. (medlineplus.gov)
- Donkey IgG F(ab')2 fragment Peroxidase conjugated secondary antibody reagents are ideal for ELISA, western blotting, Immunohistochemistry, Fluorescence Microscopy, Flow Cytometry as well as other antibody detection methods. (rockland.com)
Hydrogen7
- The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. (nih.gov)
- Is the protein surrounding the active site critical for hydrogen peroxide reduction by selenoprotein glutathione peroxidase? (umassmed.edu)
- Although the TMBZ solution is colorless, it turns bluish-green (λmax: 655 nm) in the presence of hydrogen peroxide and peroxidase. (dojindo.com)
- Peroxidase activity was measured with 4 different hydrogen donors (ferulic acid, caffeic acid, pyrocatechol and pyrogallol). (tubitak.gov.tr)
- The family of glutathione peroxidase enzymes (GPX) acts by catalyzing the conversion of hydrogen peroxide or hydroperoxides to water or corresponding alcohols, participating in enzymatic defense against damage caused by ROS. (ufrgs.br)
- There is a third natural antioxidant enzyme called, glutathione peroxidase which also reduces hydrogen peroxide to water. (yourdictionary.com)
- X-ray crystallography, kinetics, spectroscopy and directed evolution have been used to define substrate binding in recombinant soybean cystolic ascorbate peroxidase (rsAPX), which catalyses the hydrogen peroxide-dependent oxidation of ascorbate in plants. (le.ac.uk)
Glutathione and glutathione1
- In this context, the extracellular antioxidant system, comprised primarily of glutathione and glutathione peroxidase, is especially important in protecting against oxidant injury. (nih.gov)
Enzyme glutathione3
- The oxido-reductase enzyme glutathione peroxidase 4 (GPX4) governs Salmonella Typhimurium-induced neutrophil transepithelial migration. (umassmed.edu)
- This dosage induces optimum levels of the antioxidant enzyme glutathione peroxidase in the lungs. (yourdictionary.com)
- The activity of an enzyme (glutathione peroxidase ) in platelets (small blood cells essential in blood clotting) may be evaluated to assess selenium status. (yourdictionary.com)
Ascorbate peroxidase2
- Ascorbate peroxidase (APX), cytochrome c peroxidase (CcP), and the catalase - peroxidases (KatG) share very similar active site structures and are distinguished from other peroxidases by the presence of a distal tryptophan residue. (bris.ac.uk)
- The redox-sensitive transcription factor RAP2.4a mediates chloroplast-to-nucleus redox signaling and controls induction of the three most prominent chloroplast peroxidases, namely 2-Cys peroxiredoxin A (2CPA) and thylakoid- and stromal ascorbate peroxidase (tAPx and sAPx). (fu-berlin.de)
Gpx42
- Wortmann, Markus (2015): Glutathion Peroxidase 4 (Gpx4): ein Modulator der Tumorangiogenese und Endothelintegrität. (uni-muenchen.de)
- Glutathione Peroxidase 4/GPX4 " has 7 results in Products. (rndsystems.com)
Substrate1
- This structure provides new rationalization of the unusual functional features of the related cytochrome c peroxidase enzyme, and a mechanism for electron transfer from the substrate to the heme has been prepared (Chapter 3). (le.ac.uk)
Proteins1
- also known as PHGPx) is a monomeric, 21 kDa member of the glutathione peroxidase family of proteins. (rndsystems.com)
Cytochrome1
- An Improved Staining Procedure for the Detection of the Peroxidase Activity of Cytochrome p-450 on Sodium Dodecyl Sulfate Polyacrylamide Gels. (dojindo.com)
Oxidation1
- Peroxidases (PRXs) and laccases (LACs) are enzymes involved in catalyzing the oxidation of the lignin monomers to facilitate lignin polymerization . (bvsalud.org)
Extracellular2
- Induction of extracellular glutathione peroxidase occurs in airway inflammation and undoubtedly plays an important defense against oxidative injury to the airway surface. (nih.gov)
- Role of neutrophil extracellular la NETosis en las enfermedades infecciosas pulmonares. (bvsalud.org)
Selenoprotein1
- Consequences of genetic variations in the glutathione peroxidase 1 selenoprotein. (uic.edu)
Protein2
- Thyroid peroxidase is a type of protein (called an enzyme) that cells in the thyroid gland use to make thyroid hormone. (medlineplus.gov)
- Apart from various hydrolases, a high level of peroxidase activity (32 200 U/ltre medium, with specific activity of 1.3417 U/μg protein) has been obtained. (amrita.edu)
Neutrophil1
- Further, in vivo experiments using wild type and myeloperoxidase null mice showed a significantly lower degree of biodegradation and particle elimination in latter animal type, underscoring the role of neutrophil peroxidase in biodegrading carbon nanotube s. (cdc.gov)
Molecule1
- The peroxidase active site, which catalyzes the reduction of PGG2 to PGH2, is located on the other side of the molecule, at the heme binding site. (wikipedia.org)
Activity6
- The changes in reduced glutathione (GSH), activity of glutathione transferase (GST) and glutathione peroxidase (GSPx) after administration of exogenous melatonin (N-acetyl-5-methoxy-tryptamine) at a dose 20 mg/kg b.w. were investigated for five and ten days in the liver and kidney of male and female mice. (nih.gov)
- Melatonin caused an increase in glutathione level, the activity of glutathione peroxidase as well as glutathione transferase in the examined organs. (nih.gov)
- The peroxidase with an optimum activity at 50 °C was reasonably stable at 70 °C. The enzyme was active in the pH range 5-11, with an optimum at pH 6. (amrita.edu)
- Title : Ferromagnetic nanoparticles with peroxidase-like activity enhance the cleavage of biological macromolecules for biofilm elimination Personal Author(s) : Gao, Lizeng;Giglio, Krista M.;Nelson, Jacquelyn L.;Sondermann, Holger;Travis, Alexander J. (cdc.gov)
- Within the transcription factor family, RAP2.4a has a unique function as a general transcriptional activator of chloroplast peroxidase activity. (fu-berlin.de)
- 2,3,7,8-Tetrachlorodibenzo- p -dioxin as an antiestrogen: Effect on rat uterine peroxidase activity. (cdc.gov)
Gene2
- Além disso, foi obtida uma construção para transformação de arroz, contendo os genes repórteres GUS e GFP, a fim de realizar o estudo do promotor do gene da Glutationa Peroxidase 3. (ufrgs.br)
- In addition, it was obtained a construct for transformation of rice, containing the GUS and GFP reporter genes in order to study the Glutathione Peroxidase 3 gene promoter. (ufrgs.br)
Regulation1
- Phylogenetic analysis reveals that HPX15, AsP-15 and AcP-15 are unique to Anophelines and this may be due to the involvement of this peroxidase in regulation of Plasmodium development. (biomedcentral.com)
Immune1
- Donkey IgG F(ab')2 fragment Peroxidase conjugated - Secreted as part of the adaptive immune response by plasma B cells, immunoglobulin G constitutes 75% of serum immunoglobulins. (rockland.com)
Genes1
- Análise da expressão dos genes de glutationa peroxidase em arroz (Oryza sativa L. (ufrgs.br)
Reaction1
- After the peroxidase reaction, wash slide with buffer 5-7X, (this buffer should not contain any sodium azide because peroxidase is inactivated) and distilled/deionized water 2X. (immunochemistry.com)
Sensitivity1
- This Peroxidase Enhancing system increases the level of sensitivity in peroxidase based chromogens (AEC and DAB). (immunochemistry.com)
Procedure1
- To extend available double labeling procedures such as combinations of immunogold and peroxidase methods, an additional, gold- and peroxidase-independent procedure would represent a considerable advantage. (tu-berlin.de)
Catalyze1
- Peroxidases catalyze a wide variety of peroxide-dependent oxidations. (rcsb.org)
Detection systems2
- We offer a choice of either peroxidase or alkaline phosphatase based VECTASTAIN ABC kit detection systems. (vectorlabs.com)
- 1) Horseradish (Armoracia rusticana) peroxidase is used in detection systems with different substrates. (bspp.org.uk)
Content1
- For this purpose, the alkaline phosphatase product is identified by its cerium content via energy filtered transmission electron microscopy and thereby differentiated from cerium-free peroxidase-derived precipitates. (tu-berlin.de)
MeSH1
- Glutathione Peroxidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
System3
- The VECTASTAIN Elite ABC system is the most sensitive avidin/biotin-based peroxidase system and is approximately 5 times more sensitive than the original VECTASTAIN ABC Kit with the same low background. (vectorlabs.com)
- Peroxidase enzyme system is routinely used in Immunohistochemistry (IHC) and Immunocytochemistry (ICC). (immunochemistry.com)
- Using the rat olfactory bulb as model system I showed further that the new technique allows the combination with the peroxidase/diaminobenzidine system for ultrastructural double labeling. (tu-berlin.de)
Family1
- Animal heme-dependent peroxidases is a family of peroxidases. (wikipedia.org)
Role1
- The role of peroxidase and IAA oxidase activities in defense mechanisms in response to heavy metal toxicity is discussed. (tubitak.gov.tr)
Cells1
- Iodine, ingested in food and water as iodide, is actively concentrated by the thyroid and converted to organic iodine (organification) within follicular cells by thyroid peroxidase. (msdmanuals.com)
Activities2
- Peroxidase and IAA oxidase activities showed a clear inverse relation with growth. (tubitak.gov.tr)
- Histochemical Detection of Peroxidase and Laccase Activities in Populus Secondary Xylem. (bvsalud.org)
Shows1
- This graph shows the total number of publications written about "Glutathione Peroxidase" by people in this website by year, and whether "Glutathione Peroxidase" was a major or minor topic of these publications. (umassmed.edu)