BrittleDiagnosed with Osteogenesis ImperfectaDistractionHaving osteogenesis imperfectaImperfecta patientsGenetic DisorderFractures50,000Multicenter studyBonesDisorderLobsteinDeformitiesCollagenSymptomsSuffers100,000 peopleTeeth2017MeSHBone FormationSyndromeDentinogenesis imperfectaInterventionFractureCleftPatientsActorTypeAdequateMildConditionTypesMedicalSuccessfullyChildrenTreatmentsProtecting PeopleDoctorsClinicalRESEARCHBenefitsTimeTOPICLivesSpecific
Brittle10
- About 100,000 people in China suffer from osteogenesis imperfecta, a genetic and inherited disorder characterized by brittle bones. (chinadaily.com.cn)
- Type I occurs in people who have osteogenesis imperfecta , a genetic condition in which bones are brittle and easily broken. (medlineplus.gov)
- Another heart-wrenching, controversial novel by Jodi Picoult, Handle with Care introduces Willow, a smart and charming five-year-old who was born with a brittle bone disease called osteogenesis imperfecta. (simonandschuster.com)
- Osteogenesis imperfecta (OI), also known as "brittle bone disease," is a rare genetic disorder that affects the bones. (upmc.com)
- Friday was Jian Chuntian's last day at China-Dolls, the Beijing NGO that assists people with osteogenesis imperfecta, also called brittle-bone disease. (chinadaily.com.cn)
- Connor suffers from Osteogenesis Imperfecta (OI), often called brittle bone disease. (bu.edu)
- I am interested in improving bone strength in a disorder known as Osteogenesis Imperfecta (OI) or brittle bone disease. (missouri.edu)
- People with brittle bone disease have fragile bones that break with minimal trauma, severely decreasing quality of life. (missouri.edu)
- The vibrant 11-year-old was born with osteogenesis imperfecta, also known as brittle bone disease, a disorder with no cure. (rmpbs.org)
- You wouldn't be able to tell because of her constant smile, but Meg's daily life includes around-the-clock care and accessibility challenges due to her stature (people with brittle bone disease sometimes have shorter limbs or do not grow at typical rates). (rmpbs.org)
Diagnosed with Osteogenesis Imperfecta1
- Diagnosed with Osteogenesis Imperfecta (OI) as an infant, Heffernan has been in a wheelchair her whole life. (blogspot.com)
Distraction26
- An alternative intervention is known as distraction osteogenesis, which achieves bone lengthening by gradual mechanical distraction (cutting of bone and moving the ends apart incrementally to allow new bone to form in the gap). (cochrane.org)
- This review, produced through Cochrane Oral Health , examines the benefits and risks of distraction osteogenesis for advancing the upper jaw compared to conventional orthognathic surgery in adolescents and adults. (cochrane.org)
- Upper jaw was more stable in the distraction osteogenesis group than the conventional osteotomy group five years after surgery. (cochrane.org)
- This review found only one small randomised controlled trial concerning the effectiveness of distraction osteogenesis compared to conventional orthognathic surgery. (cochrane.org)
- An alternative intervention is distraction osteogenesis, which achieves bone lengthening by gradual mechanical distraction. (cochrane.org)
- To provide evidence regarding the effects and long-term results of maxillary distraction osteogenesis compared to orthognathic surgery for the treatment of hypoplastic maxilla in people with cleft lip and palate. (cochrane.org)
- In the 1950s, the Russian orthopedic surgeon, Dr. Gabriel Ilizarov slowly perfected the surgical and postoperative management of distraction osteogenesis treatment to correct deformities and repair defects of the arms and legs. (madisonaveoralsurgeon.com)
- Distraction osteogenesis was initially used to treat defects of the oral and facial region in 1990. (madisonaveoralsurgeon.com)
- Since then, the surgical and technological advances made in the field of distraction osteogenesis have provided the oral and maxillofacial surgeons with a safe and predictable method to treat selected deformities of the oral and facial skeleton. (madisonaveoralsurgeon.com)
- Dr. Press or Dr. Silverman use distraction osteogenesis to treat selected deformities and defects of the oral and facial skeleton. (madisonaveoralsurgeon.com)
- What does the term distraction osteogenesis mean? (madisonaveoralsurgeon.com)
- Simply stated, distraction osteogenesis means the slow movement apart (distraction) of two bony segments in a manner such that new bone is allowed to fill in the gap created by the separating bony segments. (madisonaveoralsurgeon.com)
- Is the surgery for distraction osteogenesis more involved than "traditional surgery" for a similar procedure? (madisonaveoralsurgeon.com)
- No. Distraction osteogenesis surgery is usually done on an outpatient basis with most of the patients going home the same day of surgery. (madisonaveoralsurgeon.com)
- Is distraction osteogenesis painful? (madisonaveoralsurgeon.com)
- Since all distraction osteogenesis surgical procedures are done while the patient is under general anesthesia, pain during the surgical procedure is not an issue. (madisonaveoralsurgeon.com)
- What are the benefits of distraction osteogenesis vs. traditional surgery for a similar condition? (madisonaveoralsurgeon.com)
- Distraction osteogenesis surgical procedures typically produce less pain and swelling than the traditional surgical procedure for a similar condition. (madisonaveoralsurgeon.com)
- Distraction osteogenesis eliminates the need for bone grafts , and therefore, another surgical site. (madisonaveoralsurgeon.com)
- Lastly, distraction osteogenesis is associated with greater stability when used in major cases where significant movement of bony segments are involved. (madisonaveoralsurgeon.com)
- What are the disadvantages of distraction osteogenesis? (madisonaveoralsurgeon.com)
- Distraction osteogenesis requires the patient to return to the surgeon's office frequently during the initial two weeks after surgery. (madisonaveoralsurgeon.com)
- Does distraction osteogenesis leave scars on the face? (madisonaveoralsurgeon.com)
- No. distraction osteogenesis works well on patients of all ages. (madisonaveoralsurgeon.com)
- Leg-lengthening procedures using distraction osteogenesis have been performed successfully. (medscape.com)
- Osteogenesis distraction and inferior alveolar nerve lateralization were performed in five (2.51%) and three (1.51%) procedures respectively. (bvsalud.org)
Having osteogenesis imperfecta1
- Figures in film, television, video games and novels depicted as having osteogenesis imperfecta include: Samuel L. Jackson's character Elijah Price in M. Night Shyamalan's 2000 film Unbreakable and its 2019 follow-up Glass, who was born with type I osteogenesis imperfecta. (wikipedia.org)
Imperfecta patients1
- A wedding ceremony is one of the highlights for osteogenesis imperfecta patients as more than 300 sufferers gathered in Beijing on Sunday. (chinadaily.com.cn)
Genetic Disorder1
- For the average baby not ultimately diagnosed with a moderate to severe form of Osteogenesis Imperfecta (OI)- a genetic disorder causing defects in quantity or quality of collagen- like Easton Elrod , fracturing a clavicle is not uncommon in a challenging vaginal birth. (acsh.org)
Fractures5
- With osteogenesis imperfecta, the goal is to keep the child walking, to protect the bone from breaking all the time so that they can walk, and also decrease the number of fractures that they have in a lifetime. (cure.org)
- As a result, people with OI are more prone to bone fractures. (upmc.com)
- People may have only a few fractures or several dozen in their lives. (upmc.com)
- People with this type of OI have frequent fractures that often decrease after puberty. (upmc.com)
- If a child has frequent fractures and other symptoms of osteogenesis imperfecta, doctors may perform tests to diagnose the condition. (upmc.com)
50,0003
- An estimated 25,000 to 50,000 Americans have OI, according to the Osteogenesis Imperfecta Foundation . (upmc.com)
- According to the Osteogenesis Imperfecta Foundation , 50,000 people are impacted in the United States. (acsh.org)
- OI affects somewhere between 20,000 and 50,000 people in America. (bu.edu)
Multicenter study2
- A multicenter study to evaluate pulmonary function in osteogenesis imperfecta. (childrensmercy.org)
- Outcome of COVID19 in Patients With Osteogenesis Imperfecta: A Retrospective Multicenter Study in Saudi Arabia. (cdc.gov)
Bones10
- Osteogenesis imperfecta is a hereditary disorder that disrupts the proper formation of bones and makes bones abnormally fragile. (msdmanuals.com)
- Most people with osteogenesis imperfecta have fragile bones, and about 50 to 65% have hearing loss. (msdmanuals.com)
- People with weakened bones can get them from a minor fall or without any trauma at all. (akronchildrens.org)
- Medical problems that cause weakened bones include osteoporosis and osteogenesis imperfecta . (akronchildrens.org)
- The term is used to describe those who suffer from osteogenesis imperfecta, a genetic and inherited disorder characterized by fragile bones. (chinadaily.com.cn)
- When Willow is born with severe osteogenesis imperfecta, her parents are devastated-she will suffer hundreds of broken bones as she grows, a lifetime of pain. (simonandschuster.com)
- People born with OI have bones that break easily - sometimes without any trauma. (upmc.com)
- The bones of a person suffering from OI are so fragile that putting a blanket on them can cause a fracture. (bu.edu)
- A genetic or heritable condition- osteogenesis imperfecta (OI) causes bones to fracture (break) readily, sometimes with no apparent cause or slight damage. (myriterx.com)
- Moreover, treatment for osteogenesis imperfecta emphasizes strengthening bones & enhancing the quality of life. (myriterx.com)
Disorder1
- An inherited bone disorder is osteogenesis imperfecta. (myriterx.com)
Lobstein1
- Osteogenesis imperfecta ( OI dan kadang-kadang dikenali sebagai penyakit tulang rapuh, atau "Lobstein syndrome" [1] ) adalah gangguan tulang genetik. (wikipedia.org)
Deformities1
- Type IV osteogenesis imperfecta ranges widely in severity and can cause deformities. (msdmanuals.com)
Collagen2
- In osteogenesis imperfecta, synthesis of collagen, one of the normal components of bone, is impaired in most affected people because of mutations in the genes that play an important role in the development of collagen. (msdmanuals.com)
- The majority of the time, osteogenesis imperfecta (OI) is caused by a modification or defect in the genes that provide the instructions for producing type I collagen. (myriterx.com)
Symptoms8
- After birth, doctors base the diagnosis of osteogenesis imperfecta on the symptoms and on a physical examination. (msdmanuals.com)
- Some people have very mild symptoms, while others have moderate or more severe symptoms. (kidshealth.org)
- There are many different symptoms of osteogenesis imperfecta. (upmc.com)
- Not all people will experience many of the symptoms. (upmc.com)
- There is no cure for osteogenesis imperfecta, but treatment can help people manage their symptoms and live a healthier life. (upmc.com)
- Most people don't notice osteoporosis symptoms until it is advanced. (bannerhealth.com)
- Because most people don't have symptoms of osteopenia or osteoporosis, it's very important to ask about bone density screening as early as age 50 if you are at risk. (bannerhealth.com)
- Other symptoms, which can be minor to severe and differ from person to person, can occur in people with OI. (myriterx.com)
Suffers1
- 1 in every 15,000 children suffers from osteogenesis imperfecta worldwide. (cure.org)
100,000 people1
- From hosting 36 support and network groups in 26 states to expanding resources or raising funds, the OI community and Foundation staff provide quality support services to more than 100,000 people each year. (oif.org)
Teeth2
- Children may have discolored and poorly developed teeth (called dentinogenesis imperfecta) depending on the type of osteogenesis imperfecta. (msdmanuals.com)
- About half of the people who have OI have teeth that appear normal, and their major concerns are routine care. (intelligentdental.com)
20171
- Asa Butterfield's character Gardner Elliot in the 2017 film The Space Between Us has with osteogenesis imperfecta due to being born on the planet Mars. (wikipedia.org)
MeSH1
- Osteogenesis Imperfecta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (childrensmercy.org)
Bone Formation1
- Osteogenesis imperfecta means "imperfect bone formation. (upmc.com)
Syndrome1
- Thus, people with the syndrome require routine dental examinations. (myriterx.com)
Dentinogenesis imperfecta4
- Dentinogenesis imperfecta type II and type III usually occur in people without other inherited disorders. (medlineplus.gov)
- Dentinogenesis imperfecta affects an estimated 1 in 6,000 to 8,000 people. (medlineplus.gov)
- Mutations in the DSPP gene have been identified in people with dentinogenesis imperfecta type II and type III. (medlineplus.gov)
- Dentinogenesis imperfecta type I occurs as part of osteogenesis imperfecta, which is caused by mutations in one of several other genes (most often the COL1A1 or COL1A2 genes). (medlineplus.gov)
Intervention2
- If there is not early intervention on children like Farida with osteogenesis imperfecta, chances are they will lose the ability to walk. (cure.org)
- But the intervention drew strong criticisms, particularly from disability rights and family support groups, who compared it to involuntary sterilization and other horrific treatments inflicted on disabled people throughout history, ostensibly for both individual and social benefit. (blogspot.com)
Fracture3
- Sometimes people with a compression fracture of the spine do not have any pain at all. (akronchildrens.org)
- Think about how a basic diaper change or a vigorous hug in a person with a more severe form of OI can elicit a fracture. (acsh.org)
- Liu W, Lee B, Nagamani SCS, Nicol L, Rauch F, Rush ET, Sutton VR, Orwoll E. Approach to the Patient: Pharmacological Therapies for Fracture Risk Reduction in Adults With Osteogenesis Imperfecta. (childrensmercy.org)
Cleft1
- The Development, Deployment, and Evaluation of the CLEFT-Q Computerized Adaptive Test: A Multimethods Approach Contributing to Personalized, Person-Centered Health Assessments in Plastic Surgery. (duke.edu)
Patients1
- Are there any age limitations for patients who can receive osteogenesis? (madisonaveoralsurgeon.com)
Actor1
- Peter Radtke - German founder of Die Deutsche Gesellschaft für Osteogenesis Imperfecta, also a philologist and actor. (wikipedia.org)
Type3
- Type I osteogenesis imperfecta is the mildest type. (msdmanuals.com)
- Type II osteogenesis imperfecta is the most severe type and causes death. (msdmanuals.com)
- Type III osteogenesis imperfecta is the most severe type that does not cause death. (msdmanuals.com)
Adequate1
- Most insurance companies will cover the cost of the osteogenesis surgical procedure provided that there is adequate and accurate documentation of the patient's condition. (madisonaveoralsurgeon.com)
Mild1
- Osteogenesis imperfecta can range from mild to severe. (msdmanuals.com)
Condition3
- But some people do not fit into one of the classified types of the condition. (upmc.com)
- If a parent has osteogenesis imperfecta or a family history of the condition, doctors may test for the condition using ultrasound or other tests. (upmc.com)
- He explained to me his rare condition and his passion for being able to give back to people and make some sort of difference in peoples lives. (bu.edu)
Types3
- There are 4 main types of osteogenesis imperfecta (I, II, III, and IV) along with other rare types. (msdmanuals.com)
- There are more than a dozen identified types of osteogenesis imperfecta. (upmc.com)
- High quality clinical trials, which involve lots of people, and different face types, are required to guide decision making. (cochrane.org)
Medical1
- The Foundation's principal education event is the OIF National Conference, which provides more than 570 people with medical, research, and coping information. (oif.org)
Successfully1
- Theoretically it is possible to do this successfully for a person with OI and there is anecdotal evidence that this has been accomplished. (intelligentdental.com)
Children7
- Now she's working together with the researcher Leanne Baird, who's a genetic counseling student, to find out more about the role OI plays when young people are making future decision about having children. (oife.org)
- Sometimes heart or lung diseases develop in children with osteogenesis imperfecta. (msdmanuals.com)
- Children like Farida rely on the support and generosity of people like you to receive surgery and comprehensive care offered at CURE hospitals. (cure.org)
- The group could not reach consensus, but it did reach a compromise: "growth attenuation can be an ethically acceptable decision because the benefits and risks are similar to those associated with other decisions that parents make for their profoundly disabled children and about which reasonable people disagree. (blogspot.com)
- Today, many of the people who serve on the Board of Directors and oversee the Foundation's operations have OI themselves or are parents of children with OI. (oif.org)
- Mid-term Results of Femoral and Tibial Osteotomies and Fassier-Duval Nailing in Children With Osteogenesis Imperfecta. (childrensmercy.org)
- Hunter et al recommend that children with achondroplasia remain within 1 standard deviation of the mean weight/height (W/H) curve for people with achondroplasia. (medscape.com)
Treatments1
- The Foundation's mission is to improve the quality of life for people affected by OI through research to find treatments and a cure, education, awareness, and mutual support. (oif.org)
Protecting People1
- Protecting People. (cdc.gov)
Doctors1
- In many cases, doctors can diagnose osteogenesis imperfecta before a baby is born. (upmc.com)
Clinical1
- Objective To analyze the characteristic of molecular genetics and clinical manifestations in 2 families with osteogenesis imperfecta (OI). (j-bio.net)
RESEARCH3
- The Seattle Growth Attenuation and Ethics Working Group consisted of 20 people, including Erik Parens, senior research scholar at The Hastings Center, as well as pediatricians, lawyers, and philosophers with diverse perspectives and experiences on disability issues. (blogspot.com)
- The mission of the OI Foundation is to improve the quality of life for those living with osteogenesis imperfecta through research, education, awareness, and mutual support. (oif.org)
- Research involves a particular focus on angiogenesis, endoplasmic reticulum stress, multi-potent progenitor cells and osteogenesis. (otago.ac.nz)
Benefits1
- Dr Timothy Sharp (aka Dr Happy), chief happiness officer at The Happiness Institute, says that he has 'absolutely no doubt that people can exercise their brains and enjoy benefits such as happiness… just like when we exercise our bodies we enjoy benefits such as fitness and strength. (suncorp.com.au)
Time2
- This exercise program has been designed for individuals who have osteogenesis imperfecta (OI) and spend most of their time in a wheelchair or seated. (hss.edu)
- According to the guys on BU's basketball team, Connor is considered "the least narp narp of all time" (a "narp" is a non-athlete, regular person). (bu.edu)
TOPIC2
- This graph shows the total number of publications written about "Osteogenesis Imperfecta" by people in this website by year, and whether "Osteogenesis Imperfecta" was a major or minor topic of these publications. (childrensmercy.org)
- These topic labels come from the works of this person. (lu.se)
Lives1
- He explained to me how he wouldn't be as passionate and excited to compete if it was just a regular shoot out, but the fact that he gets to be the person in charge of asking for donations and creating a difference in so many people's lives makes the experience more exciting. (bu.edu)
Specific1
- While I realize you can't give an exact number for a specific person, in your experience how long would you generally expect linear progress to last (or to what weight)? (startingstrength.com)